Insights from metagenome-assembled genomes on the genetic stability and safety of over-the-counter probiotic products
Curr Genet. 2023 May 26. doi: 10.1007/s00294-023-01271-5. Online ahead of print.ABSTRACTThe demand for and acceptance of probiotics is determined by their quality and safety. Illumina NGS sequencing and analytics were used to examine eight marketed probiotics. Up to the species level, sequenced DNA was taxonomically identified, and relative abundances were determined using Kaiju. The genomes were constructed using GTDB and validated through PATRICK and TYGS. A FastTree 2 phylogenetic tree was constructed using several type strain sequences from relevant species. Bacteriocin and ribosomally synthesized polypeptide (RiPP) ge...
Source: Current Genetics - May 26, 2023 Category: Genetics & Stem Cells Authors: Ghazal Aziz Arsalan Zaidi Daniel J O ' Sullivan Source Type: research
Insights from metagenome-assembled genomes on the genetic stability and safety of over-the-counter probiotic products
Curr Genet. 2023 May 26. doi: 10.1007/s00294-023-01271-5. Online ahead of print.ABSTRACTThe demand for and acceptance of probiotics is determined by their quality and safety. Illumina NGS sequencing and analytics were used to examine eight marketed probiotics. Up to the species level, sequenced DNA was taxonomically identified, and relative abundances were determined using Kaiju. The genomes were constructed using GTDB and validated through PATRICK and TYGS. A FastTree 2 phylogenetic tree was constructed using several type strain sequences from relevant species. Bacteriocin and ribosomally synthesized polypeptide (RiPP) ge...
Source: Current Genetics - May 26, 2023 Category: Genetics & Stem Cells Authors: Ghazal Aziz Arsalan Zaidi Daniel J O ' Sullivan Source Type: research
Amyloids and prions in the light of evolution
Curr Genet. 2023 May 10. doi: 10.1007/s00294-023-01270-6. Online ahead of print.ABSTRACTFunctional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates. Intracellular and extracellular amyloid fibrils of different proteins perform storage, protective, structural, and regulatory functions. The structural organization of amyloid fibrils determines their unique physical and biochemical properties. The formation of these fibrillar structures can provide adaptive advantages that are picked up by natural selection. Despite the great interest in functional and pathologica...
Source: Current Genetics - May 10, 2023 Category: Genetics & Stem Cells Authors: Alexey P Galkin Evgeniy I Sysoev Anna A Valina Source Type: research
Amyloids and prions in the light of evolution
Curr Genet. 2023 May 10. doi: 10.1007/s00294-023-01270-6. Online ahead of print.ABSTRACTFunctional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates. Intracellular and extracellular amyloid fibrils of different proteins perform storage, protective, structural, and regulatory functions. The structural organization of amyloid fibrils determines their unique physical and biochemical properties. The formation of these fibrillar structures can provide adaptive advantages that are picked up by natural selection. Despite the great interest in functional and pathologica...
Source: Current Genetics - May 10, 2023 Category: Genetics & Stem Cells Authors: Alexey P Galkin Evgeniy I Sysoev Anna A Valina Source Type: research
Amyloids and prions in the light of evolution
Curr Genet. 2023 May 10. doi: 10.1007/s00294-023-01270-6. Online ahead of print.ABSTRACTFunctional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates. Intracellular and extracellular amyloid fibrils of different proteins perform storage, protective, structural, and regulatory functions. The structural organization of amyloid fibrils determines their unique physical and biochemical properties. The formation of these fibrillar structures can provide adaptive advantages that are picked up by natural selection. Despite the great interest in functional and pathologica...
Source: Current Genetics - May 10, 2023 Category: Genetics & Stem Cells Authors: Alexey P Galkin Evgeniy I Sysoev Anna A Valina Source Type: research
Amyloids and prions in the light of evolution
Curr Genet. 2023 May 10. doi: 10.1007/s00294-023-01270-6. Online ahead of print.ABSTRACTFunctional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates. Intracellular and extracellular amyloid fibrils of different proteins perform storage, protective, structural, and regulatory functions. The structural organization of amyloid fibrils determines their unique physical and biochemical properties. The formation of these fibrillar structures can provide adaptive advantages that are picked up by natural selection. Despite the great interest in functional and pathologica...
Source: Current Genetics - May 10, 2023 Category: Genetics & Stem Cells Authors: Alexey P Galkin Evgeniy I Sysoev Anna A Valina Source Type: research
Amyloids and prions in the light of evolution
Curr Genet. 2023 May 10. doi: 10.1007/s00294-023-01270-6. Online ahead of print.ABSTRACTFunctional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates. Intracellular and extracellular amyloid fibrils of different proteins perform storage, protective, structural, and regulatory functions. The structural organization of amyloid fibrils determines their unique physical and biochemical properties. The formation of these fibrillar structures can provide adaptive advantages that are picked up by natural selection. Despite the great interest in functional and pathologica...
Source: Current Genetics - May 10, 2023 Category: Genetics & Stem Cells Authors: Alexey P Galkin Evgeniy I Sysoev Anna A Valina Source Type: research
Amyloids and prions in the light of evolution
Curr Genet. 2023 May 10. doi: 10.1007/s00294-023-01270-6. Online ahead of print.ABSTRACTFunctional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates. Intracellular and extracellular amyloid fibrils of different proteins perform storage, protective, structural, and regulatory functions. The structural organization of amyloid fibrils determines their unique physical and biochemical properties. The formation of these fibrillar structures can provide adaptive advantages that are picked up by natural selection. Despite the great interest in functional and pathologica...
Source: Current Genetics - May 10, 2023 Category: Genetics & Stem Cells Authors: Alexey P Galkin Evgeniy I Sysoev Anna A Valina Source Type: research
Amyloids and prions in the light of evolution
Curr Genet. 2023 May 10. doi: 10.1007/s00294-023-01270-6. Online ahead of print.ABSTRACTFunctional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates. Intracellular and extracellular amyloid fibrils of different proteins perform storage, protective, structural, and regulatory functions. The structural organization of amyloid fibrils determines their unique physical and biochemical properties. The formation of these fibrillar structures can provide adaptive advantages that are picked up by natural selection. Despite the great interest in functional and pathologica...
Source: Current Genetics - May 10, 2023 Category: Genetics & Stem Cells Authors: Alexey P Galkin Evgeniy I Sysoev Anna A Valina Source Type: research
Amyloids and prions in the light of evolution
Curr Genet. 2023 May 10. doi: 10.1007/s00294-023-01270-6. Online ahead of print.ABSTRACTFunctional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates. Intracellular and extracellular amyloid fibrils of different proteins perform storage, protective, structural, and regulatory functions. The structural organization of amyloid fibrils determines their unique physical and biochemical properties. The formation of these fibrillar structures can provide adaptive advantages that are picked up by natural selection. Despite the great interest in functional and pathologica...
Source: Current Genetics - May 10, 2023 Category: Genetics & Stem Cells Authors: Alexey P Galkin Evgeniy I Sysoev Anna A Valina Source Type: research
Amyloids and prions in the light of evolution
Curr Genet. 2023 May 10. doi: 10.1007/s00294-023-01270-6. Online ahead of print.ABSTRACTFunctional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates. Intracellular and extracellular amyloid fibrils of different proteins perform storage, protective, structural, and regulatory functions. The structural organization of amyloid fibrils determines their unique physical and biochemical properties. The formation of these fibrillar structures can provide adaptive advantages that are picked up by natural selection. Despite the great interest in functional and pathologica...
Source: Current Genetics - May 10, 2023 Category: Genetics & Stem Cells Authors: Alexey P Galkin Evgeniy I Sysoev Anna A Valina Source Type: research
Amyloids and prions in the light of evolution
Curr Genet. 2023 May 10. doi: 10.1007/s00294-023-01270-6. Online ahead of print.ABSTRACTFunctional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates. Intracellular and extracellular amyloid fibrils of different proteins perform storage, protective, structural, and regulatory functions. The structural organization of amyloid fibrils determines their unique physical and biochemical properties. The formation of these fibrillar structures can provide adaptive advantages that are picked up by natural selection. Despite the great interest in functional and pathologica...
Source: Current Genetics - May 10, 2023 Category: Genetics & Stem Cells Authors: Alexey P Galkin Evgeniy I Sysoev Anna A Valina Source Type: research
Amyloids and prions in the light of evolution
Curr Genet. 2023 May 10. doi: 10.1007/s00294-023-01270-6. Online ahead of print.ABSTRACTFunctional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates. Intracellular and extracellular amyloid fibrils of different proteins perform storage, protective, structural, and regulatory functions. The structural organization of amyloid fibrils determines their unique physical and biochemical properties. The formation of these fibrillar structures can provide adaptive advantages that are picked up by natural selection. Despite the great interest in functional and pathologica...
Source: Current Genetics - May 10, 2023 Category: Genetics & Stem Cells Authors: Alexey P Galkin Evgeniy I Sysoev Anna A Valina Source Type: research
Amyloids and prions in the light of evolution
Curr Genet. 2023 May 10. doi: 10.1007/s00294-023-01270-6. Online ahead of print.ABSTRACTFunctional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates. Intracellular and extracellular amyloid fibrils of different proteins perform storage, protective, structural, and regulatory functions. The structural organization of amyloid fibrils determines their unique physical and biochemical properties. The formation of these fibrillar structures can provide adaptive advantages that are picked up by natural selection. Despite the great interest in functional and pathologica...
Source: Current Genetics - May 10, 2023 Category: Genetics & Stem Cells Authors: Alexey P Galkin Evgeniy I Sysoev Anna A Valina Source Type: research
Amyloids and prions in the light of evolution
Curr Genet. 2023 May 10. doi: 10.1007/s00294-023-01270-6. Online ahead of print.ABSTRACTFunctional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates. Intracellular and extracellular amyloid fibrils of different proteins perform storage, protective, structural, and regulatory functions. The structural organization of amyloid fibrils determines their unique physical and biochemical properties. The formation of these fibrillar structures can provide adaptive advantages that are picked up by natural selection. Despite the great interest in functional and pathologica...
Source: Current Genetics - May 10, 2023 Category: Genetics & Stem Cells Authors: Alexey P Galkin Evgeniy I Sysoev Anna A Valina Source Type: research
