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Seroprevalence and associated risk factors for Toxoplasma gondii in water buffaloes (Bubalus bubalis) in Egypt
Comp Immunol Microbiol Infect Dis. 2023 Sep 2;101:102058. doi: 10.1016/j.cimid.2023.102058. Online ahead of print.ABSTRACTToxoplasmosis is a parasitic disease caused by Toxoplasma gondii and affecting all warm-blooded animals. The available data about the epidemiological situation of T. gondii in water buffaloes in Egypt are scarce. Thus, a cross-sectional study was conducted to determine the seroprevalence of T. gondii in water buffaloes in three Egyptian governorates and to evaluate the associated risk factors for the infection. A total of 430 sera samples were examined using commercial Indirect ELISA Multi-species kit. ...
Source: Comparative immunology, microbiology and infectious diseases. - September 6, 2023 Category: Allergy & Immunology Authors: Abdelfattah Selim Ayed Alshammari Hattan S Gattan Mohammed H Alruhaili Gehan A Rashed Salma Shoulah Source Type: research

Oncogenic viral DNA related to human breast cancer found on cattle milk and meat
Comp Immunol Microbiol Infect Dis. 2023 Aug 27;101:102053. doi: 10.1016/j.cimid.2023.102053. Online ahead of print.ABSTRACTBovine leukemia virus (BLV) is a major cause of lymphoma in cattle and has been recently correlated to breast cancer in humans. How and whether BLV might reach humans remains unknown but it could be through cattle-derived milk and meat. Here our aim was to investigate whether BLV DNA could be found in fresh milk and raw meat destined to human consumption and whether anti-BLV antibodies could be detected in human blood at the same geographical region. Milk (n = 36) and meat (n = 54) samples were collect...
Source: Comparative immunology, microbiology and infectious diseases. - September 6, 2023 Category: Allergy & Immunology Authors: Daniel Lazzari de Quadros Vitoria Agnoletto Ribeiro Mariana Antunes Rezende Yasmin Ampese Mat é M árcio Alexandro Gomes Katia Secchi Daisy Maria Strottmann Rafael Frandoloso Luiz Carlos Kreutz Source Type: research

Molecular evidence of Bartonella spp. in wild lowland tapirs (Tapirus terrestris), the largest land mammals in Brazil
Comp Immunol Microbiol Infect Dis. 2023 Aug 23;101:102042. doi: 10.1016/j.cimid.2023.102042. Online ahead of print.ABSTRACTThe genus Bartonella (Hyphomicrobiales: Bartonellaceae) encompasses facultative intracellular α-proteobacteria that parasite erythrocytes and endothelial cells from a wide range of vertebrate hosts and can cause disease in animals and humans. Considering the large diversity of vertebrate species that may act as reservoirs and arthropod species that may be associated with Bartonella transmission, the exposure of animals and humans to these microorganisms is likely underestimated. The present study aime...
Source: Comparative immunology, microbiology and infectious diseases. - September 3, 2023 Category: Allergy & Immunology Authors: Anna Claudia Baumel Mongruel Em ília Patrícia Medici Ariel da Costa Canena Clara Morato Dias Rosangela Zacarias Machado Marcos Rog ério André Source Type: research

Relationship of Salmonella isolation with different serum and inflammatory intestinal parameters in natural fowl typhoid outbreaks from laying hens
Comp Immunol Microbiol Infect Dis. 2023 Aug 27;101:102055. doi: 10.1016/j.cimid.2023.102055. Online ahead of print.ABSTRACTOur study was undertaken to determine the best samples and selective-diﬀerential plating media to be used for Salmonella spp. isolation. We also compared hematological and serum biochemical values, Salmonella biovar Gallinarum (SG) detection (isolation and serological test), and inflammatory intestinal response (fecal leukocyte) in laying hens with naturally occurring fowl typhoid outbreaks. Furthermore, we looked for a biomarker of SG infection. Spleen, liver, ovarian follicle content, and bone marr...
Source: Comparative immunology, microbiology and infectious diseases. - September 1, 2023 Category: Allergy & Immunology Authors: Mario Alberto Soria Eduardo Ignacio Godano Leonardo Esteban Leiva Dante Javier Bueno Source Type: research

Genomic characterization and phylogenetic analysis of Aleutian mink disease virus identified in a sudden death mink case
This study was first to investigate the association of sudden death of adult breeding minks with AMDV infection. Our findings provide useful suggestions for evaluation of the pathogenic potential of AMDV, additional details on AMDV genome characterization were also presented. Future work should focus on the importance of AMDV-LM strain in mink infection.PMID:37651788 | DOI:10.1016/j.cimid.2023.102052 (Source: Comparative immunology, microbiology and infectious diseases.)
Source: Comparative immunology, microbiology and infectious diseases. - August 31, 2023 Category: Allergy & Immunology Authors: Xingyang Cui Yan Yang Fang Wang Jilong Luo Ping Zhang Hongyan Chen Lili Zhao Junwei Ge Source Type: research

Characterization of a gE/gI/TK gene-deleted pseudorabies virus variant expressing the Cap protein of porcine circovirus type 2d
Comp Immunol Microbiol Infect Dis. 2023 Aug 27;101:102054. doi: 10.1016/j.cimid.2023.102054. Online ahead of print.ABSTRACTPorcine circovirus type 2 (PCV2) plays a key role in the etiology of PCV2-associated disease (PCVAD), and its predominant strain is PCV2d which is not completely controlled by most commercially available vaccines against PCV2a strains. Pseudorabies (PR) caused by pseudorabies virus (PRV) variants re-emerged in Bartha-K61 vaccine-immunized swine herds in late 2011, which brought considerable losses to the global pig husbandry. Therefore, it is significantly important to develop a safe and effective vacc...
Source: Comparative immunology, microbiology and infectious diseases. - August 31, 2023 Category: Allergy & Immunology Authors: Rui-Qin Xu Lin-Qing Wang Hui-Hua Zheng Run-Bo Tian Lan-Lan Zheng Shi-Jie Ma Hong-Ying Chen Source Type: research

A preliminary study to develop a lateral flow assay using recombinant GRA1 protein for the diagnosis of toxoplasmosis in stray cats
In this study, a lateral flow assay (LFA) was designed to rapidly diagnose toxoplasmosis in cats. For this purpose, we selected GRA1 protein of T. gondii due to its high antigenicity in diagnostic and vaccine studies. We further analyzed the immunological properties of GRA1 protein using in silico tools. Then, we expressed and purified recombinant GRA1 (rGRA1) protein and used it during the development of LFA to detect toxoplasmosis in serum samples (n = 40) of cats. According to the results, rGRA1 protein has negative GRAVY value, high aliphatic index, alpha helix, random coil and 12 B cell epitopes. The in silico data su...
Source: Comparative immunology, microbiology and infectious diseases. - August 30, 2023 Category: Allergy & Immunology Authors: Aysu De ğirmenci Döşkaya H üseyin Can Ayt ül Gül Tu ğba Karakavuk Mervenur G üvendi Muhammet Karakavuk Ceren G ül Sedef Erkunt Alak Cemal Ün Adnan Y üksel Gürüz Mert D öşkaya Source Type: research

Clinical findings and prognostic factors for mortality in hospitalized dogs with leishmaniosis: aretrospective study
Comp Immunol Microbiol Infect Dis. 2023 Aug 23;101:102041. doi: 10.1016/j.cimid.2023.102041. Online ahead of print.ABSTRACTThis retrospective study evaluated factors responsible for mortality of dogs hospitalized for Canine Leishmaniosis. Medical records of 31 dogs with leishmaniosis from a Portuguese Veterinary Teaching Hospital were examined between August 2018 and January 2022. Females (n = 18) and pure breed dogs (n = 27) were overrepresented, with higher frequency of Labrador Retriever (n = 4). Median age was 7 years (interquartile range=7). Most had historical findings of lethargy (n = 26) and the commonest clinicopa...
Source: Comparative immunology, microbiology and infectious diseases. - August 27, 2023 Category: Allergy & Immunology Authors: Carlota Carvalho Molina Maria Joana Dias Tiago Dias Domingues Ryane E Englar Rodolfo Oliveira Leal Source Type: research