Fibrin Clots Maintain the Viability and Proliferative Capacity of Human Mesenchymal Stem Cells: An In Vitro Study.
CONCLUSION: These preliminary in vitro results show that human MSCs mixed in unclotted fresh human venous blood were nearly completely captured in fibrin clots and that seeded MSCs were capable of maintaining their viability, proliferation capacity, and osteogenic differentiation capacity in the fibrin clot for up to 7 days, independent of external sources of nutrition. CLINICAL RELEVANCE: Fresh human fibrin clots have been used clinically for more than 30 years to improve soft-tissue healing, albeit with scar tissue. Our results demonstrate that allogenic human MSCs, which reduce soft-tissue scarring, can be captured...
Source: Clinical Orthopaedics and Related Research - December 11, 2019 Category: Orthopaedics Authors: Warth RJ, Shupe PG, Gao X, Syed M, Lowe WR, Huard J, Harner CD Tags: Clin Orthop Relat Res Source Type: research

Classification in Brief: AO Thoracolumbar Classification System.
PMID: 31834162 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - December 9, 2019 Category: Orthopaedics Authors: Vu C, Gendelberg D Tags: Clin Orthop Relat Res Source Type: research

External Validation of PATHFx Version 3.0 in Patients Treated Surgically and Non-surgically for Symptomatic Skeletal Metastases.
Abstract BACKGROUND: PATHFx is a clinical decision-support tool based on machine learning capable of estimating the likelihood of survival after surgery for patients with skeletal metastases. The applicability of any machine-learning tool depends not only on successful external validation in unique patient populations but also on remaining relevant as more effective systemic treatments are introduced. With advancements in the treatment of metastatic disease, it is our responsibility to patients to ensure clinical support tools remain contemporary and accurate. QUESTION/PURPOSES: Therefore, we sought to (1) ge...
Source: Clinical Orthopaedics and Related Research - December 6, 2019 Category: Orthopaedics Authors: Anderson AB, Wedin R, Fabbri N, Boland P, Healey J, Forsberg JA Tags: Clin Orthop Relat Res Source Type: research

Does Augmented Reality-based Portable Navigation System Improve the Accuracy of Acetabular Component Orientation During THA?
CONCLUSIONS: This system yielded no differences in acetabular anteversion accuracy, and no clinically important differences in acetabular inclination. Therefore, at this time we cannot recommend this device as its costs and risks cannot be justified based on the absence of a clinically meaningful difference in cup placement accuracy. Although we detected no complications, this was a small series, and this approach adds both surgical time and pins in the ilium. LEVEL OF EVIDENCE: Level I, therapeutic study. PMID: 31834164 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - December 6, 2019 Category: Orthopaedics Authors: Ogawa H, Kurosaka K, Sato A, Hirasawa N, Matsubara M, Tsukada S Tags: Clin Orthop Relat Res Source Type: research

On Patient Safety: Orthopaedic Surgeons Must Stop Performing Arthroscopic Partial Meniscectomy on Patients with Arthritic Knees.
PMID: 31809288 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - December 5, 2019 Category: Orthopaedics Authors: Rickert J Tags: Clin Orthop Relat Res Source Type: research

Is Lower-limb Alignment Associated with Hindfoot Deformity in the Coronal Plane? A Weightbearing CT Analysis.
Abstract BACKGROUND: The goals of lower limb reconstruction are to restore alignment, to improve function, and to reduce pain. However, it remains unclear whether alignment of the lower limb and hindfoot are associated because an accurate assessment of hindfoot deformities has been limited by superposition on plain radiography. Consequently, surgeons often overlook hindfoot deformity when planning orthopaedic procedures of the lower limb. Therefore, we used weight-bearing CT to quantify hindfoot deformity related to lower limb alignment in the coronal plane. QUESTIONS/PURPOSES: (1) Is lower-limb alignment dif...
Source: Clinical Orthopaedics and Related Research - December 3, 2019 Category: Orthopaedics Authors: Burssens ABM, Buedts K, Barg A, Vluggen E, Demey P, Saltzman CL, Victor JMK Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Combined Intravenous and Intraarticular Tranexamic Acid Does Not Offer Additional Benefit Compared with Intraarticular Use Alone in Bilateral TKA: A Randomized Controlled Trial.
CORR Insights®: Combined Intravenous and Intraarticular Tranexamic Acid Does Not Offer Additional Benefit Compared with Intraarticular Use Alone in Bilateral TKA: A Randomized Controlled Trial. Clin Orthop Relat Res. 2019 Dec 03;: Authors: Grecula MJ PMID: 31809290 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - December 3, 2019 Category: Orthopaedics Authors: Grecula MJ Tags: Clin Orthop Relat Res Source Type: research

Editorial: Thanking CORR's Peer Reviewers.
PMID: 31764320 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Leopold SS Tags: Clin Orthop Relat Res Source Type: research

Editor's Spotlight/Take 5: Is Insurance Status Associated with the Likelihood of Operative Treatment of Clavicle Fractures?
PMID: 31764321 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Leopold SS Tags: Clin Orthop Relat Res Source Type: research

Is Insurance Status Associated with the Likelihood of Operative Treatment of Clavicle Fractures?
Abstract BACKGROUND: Most closed clavicle fractures are treated nonoperatively. Research during the past decade has reported differences in the treatment of clavicle fractures based on insurance status in the US and may highlight unmet needs in a vulnerable population, particularly because new data show that surgery may lead to improved outcomes in select populations. Large-scale, national data are needed to better inform this debate. QUESTIONS/PURPOSES: (1) Does the likelihood of operative fixation of closed clavicle fractures vary among patients with different types of insurance? (2) What demographic and so...
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Congiusta DV, Amer KM, Merchant AM, Vosbikian MM, Ahmed IH Tags: Clin Orthop Relat Res Source Type: research

Clinical Faceoff: Should Orthopaedic Surgeons Have Strict BMI Cutoffs for Performing Primary TKA and THA?
PMID: 31764323 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Ricciardi BF, Giori NJ, Fehring TK Tags: Clin Orthop Relat Res Source Type: research

Not the Last Word: Roll Them Bones-Selecting Orthopaedic Surgery Residents by Lottery.
PMID: 31764324 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Bernstein J Tags: Clin Orthop Relat Res Source Type: research

Virtue Ethics in a Value-driven World: Ethical Telemedicine.
PMID: 31764325 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Humbyrd CJ Tags: Clin Orthop Relat Res Source Type: research

From Bench to Bedside: Synthesizing Better Replacements and Reconstructions.
PMID: 31764326 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Potter BK Tags: Clin Orthop Relat Res Source Type: research

Your Best Life: Unlock More Time in Your Day for Rest and Relaxation-That's an Order.
PMID: 31764327 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Kelly JD Tags: Clin Orthop Relat Res Source Type: research

Giants of Orthopaedic Surgery: Henry J. Mankin MD.
PMID: 31764328 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Hornicek FJ Tags: Clin Orthop Relat Res Source Type: research

ArtiFacts: Fighting Wartime Wound Infections with the Carrel-Dakin Method.
PMID: 31764329 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Hawk AJ Tags: Clin Orthop Relat Res Source Type: research

Depression and Non-modifiable Patient Factors Associated with Patient Satisfaction in an Academic Orthopaedic Outpatient Clinic: Is it More Than a Provider Issue?
CONCLUSIONS: Given the association of depression with lower satisfaction with a single visit at the orthopaedic clinic, providers should screen for depression and address the issue during the outpatient encounter. The impact of such comprehensive care or subsequent treatment of depression on improving patient-reported satisfaction offers areas of future study. LEVEL OF EVIDENCE: Level III, therapeutic study. PMID: 31764330 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Tisano BK, Nakonezny PA, Gross BS, Martinez JR, Wells JE Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Depression and Non-modifiable Patient Factors Associated with Patient Satisfaction in an Academic Orthopaedic Outpatient Clinic: Is it More Than a Provider Issue?
CORR Insights®: Depression and Non-modifiable Patient Factors Associated with Patient Satisfaction in an Academic Orthopaedic Outpatient Clinic: Is it More Than a Provider Issue? Clin Orthop Relat Res. 2019 Dec;477(12):2662-2664 Authors: Novicoff WM PMID: 31764331 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Novicoff WM Tags: Clin Orthop Relat Res Source Type: research

What are the Implications of Excessive Internet Searches for Medical Information by Orthopaedic Patients?
Abstract BACKGROUND: Cyberchondria may be defined as heightened distress evoked through excessive searches of the internet for medical information. In healthy people, cyberchondria is associated with a greater intolerance of uncertainty and greater health anxiety. These relationships are likely bidirectional. People who have a greater intolerance of uncertainty may be more likely to search the internet for medical information and have greater health anxiety. This greater health anxiety may lead to an increased likelihood of engaging in further internet searches and greater intolerance of uncertainty. These three c...
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Blackburn J, Fischerauer SF, Talaei-Khoei M, Chen NC, Oh LS, Vranceanu AM Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: What are the Implications of Excessive Internet Searches for Medical Information by Orthopaedic Patients?
CORR Insights®: What are the Implications of Excessive Internet Searches for Medical Information by Orthopaedic Patients? Clin Orthop Relat Res. 2019 Dec;477(12):2674-2676 Authors: Crijns TJ PMID: 31764333 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Crijns TJ Tags: Clin Orthop Relat Res Source Type: research

Prediction of Autograft Hamstring Size for Anterior Cruciate Ligament Reconstruction Using MRI.
Abstract BACKGROUND: Hamstring autografts with a diameter of less than 8 mm for ACL reconstruction have an increased risk of failure, but there is no consensus regarding the best method to predict autograft size in ACL reconstruction. QUESTIONS/PURPOSES: (1) What is the relationship between hamstring cross-section on preoperative MRI and intraoperative autograft size? (2) What is the minimum hamstring tendon cross-sectional area on MRI needed to produce an autograft of at least 8 mm at its thickest point? METHODS: This was a retrospective cohort study of 68 patients. We collectively reviewed patients who...
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Hollnagel K, Johnson BM, Whitmer KK, Hanna A, Miller TK Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Prediction of Autograft Hamstring Size for Anterior Cruciate Ligament Reconstruction Using MRI.
CORR Insights®: Prediction of Autograft Hamstring Size for Anterior Cruciate Ligament Reconstruction Using MRI. Clin Orthop Relat Res. 2019 Dec;477(12):2685-2686 Authors: Nuber GW PMID: 31764335 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Nuber GW Tags: Clin Orthop Relat Res Source Type: research

The "Cough Trick" Reduces Pain During Removal of Closed-suction Drains after Total Knee Arthroplasty: A Randomized Trial.
The "Cough Trick" Reduces Pain During Removal of Closed-suction Drains after Total Knee Arthroplasty: A Randomized Trial. Clin Orthop Relat Res. 2019 Dec;477(12):2687-2691 Authors: Yuenyongviwat V, Iamthanaporn K, Tuntarattanapong P, Hongnaparak T Abstract BACKGROUND: Drain removal after TKA can be painful. Prior research suggests that the "cough trick," in which a patient coughs at the same time she or he receives an injection, effectively decreases pain. To our knowledge, this intervention has not been evaluated as a way to reduce pain during other brief but painful interventions...
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Yuenyongviwat V, Iamthanaporn K, Tuntarattanapong P, Hongnaparak T Tags: Clin Orthop Relat Res Source Type: research

Are Skin Fiducials Comparable to Bone Fiducials for Registration When Planning Navigation-assisted Musculoskeletal Tumor Resections in a Cadaveric Simulated Tumor Model?
CONCLUSIONS: In this pilot study, skin fiducial markers were easy to identify on the skin surface of the cadaver model and on CT images used to plan margins. This technique appears to be an accurate way to plan margins in this model, but it needs to be tested thoroughly in patients to determine if it may be a better clinical approach than with bone fiducials. CLINICAL RELEVANCE: The margins obtained using skin fiducials and bone fiducials for registration were similar and comparable in this pilot study with a very small effect size. Boundaries of the simulated tumors were not violated in any resections. Skin fiducials...
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Zamora R, Punt SE, Christman-Skieller C, Yildirim C, Shapton JC, Conrad EU Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Are Skin Fiducials Comparable to Bone Fiducials for Registration When Planning Navigation-assisted Musculoskeletal Tumor Resections in a Cadaveric Simulated Tumor Model?
CORR Insights®: Are Skin Fiducials Comparable to Bone Fiducials for Registration When Planning Navigation-assisted Musculoskeletal Tumor Resections in a Cadaveric Simulated Tumor Model? Clin Orthop Relat Res. 2019 Dec;477(12):2702-2704 Authors: Temple HT PMID: 31764338 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Temple HT Tags: Clin Orthop Relat Res Source Type: research

What is the Likelihood That Tumor Endoprostheses Will Experience a Second Complication After First Revision in Patients With Primary Malignant Bone Tumors And What Are Potential Risk Factors?
CONCLUSIONS: Patients who undergo revision to treat a first megaprosthetic complication must be counseled regarding the high risk of future complications. With second complications occurring relatively soon after the first revision, regular orthopaedic follow-up visits are advised. Preoperative rather than postoperative radiotherapy should be performed when possible. Future studies should evaluate the effectiveness of different approaches in treating complications considering implant survivorship free of revision for a second complication. LEVEL OF EVIDENCE: Level III, therapeutic study. PMID: 31764339 [PubMed - ...
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Theil C, Röder J, Gosheger G, Deventer N, Dieckmann R, Schorn D, Hardes J, Andreou D Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: What is the Likelihood That Tumor Endoprostheses Will Experience a Second Complication After First Revision in Patients With Primary Malignant Bone Tumors And What Are Potential Risk Factors?
CORR Insights®: What is the Likelihood That Tumor Endoprostheses Will Experience a Second Complication After First Revision in Patients With Primary Malignant Bone Tumors And What Are Potential Risk Factors? Clin Orthop Relat Res. 2019 Dec;477(12):2715-2717 Authors: Gilg MM PMID: 31764340 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Gilg MM Tags: Clin Orthop Relat Res Source Type: research

Early Mechanical Failure of a Tumoral Endoprosthesic Rotating Hinge in the Knee: Does Bumper Wear Contribute to Hyperextension Failure?
CONCLUSIONS: The Zimmer Segmental rotating-hinge tumoral prosthesis underwent revision for implant breakage at short term in three of six patients after tumor resection and reconstruction of the knee. Bumper breakage was associated with posterior instability that was related to wear of the bushing blocking system. We are unaware of reports of these issues by other observers or in other prosthetic designs, but we feel larger registries should be created to see if this failure mechanism has been observed by others. If so, this design needs to be improved or the blocking system should be avoided.Level of Evidence Level IV, th...
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Barrientos-Ruiz I, Ortiz-Cruz EJ, Peleteiro-Pensado M, Merino-Rueda R Tags: Clin Orthop Relat Res Source Type: research

What Regions of the Distal Clavicle Have the Greatest Bone Mineral Density and Cortical Thickness? A Cadaveric Study.
Abstract BACKGROUND: Osteosynthesis of distal clavicle fractures can be challenging because of comminution, poor bone quality, and deforming forces at the fracture site. A better understanding of regional differences in the bone structure of the distal clavicle is critical to refine fracture fixation strategies, but the variations in BMD and cortical thickness throughout the distal clavicle have not been previously described. PURPOSE: /questions (1) Which distal clavicular regions have the greatest BMD? (2) Which distal clavicular regions have the greatest cortical thickness values? METHODS: Ten distal c...
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Chen RE, Soin SP, El-Shaar R, Nicandri GT, Awad HA, Maloney MD, Voloshin I Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: What Regions of the Distal Clavicle Have the Greatest Bone Mineral Density and Cortical Thickness? A Cadaveric Study.
CORR Insights®: What Regions of the Distal Clavicle Have the Greatest Bone Mineral Density and Cortical Thickness? A Cadaveric Study. Clin Orthop Relat Res. 2019 Dec;477(12):2733-2734 Authors: Gutiérrez S PMID: 31764343 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Gutiérrez S Tags: Clin Orthop Relat Res Source Type: research

Patients With Thumb-base Osteoarthritis Scheduled for Surgery Have More Symptoms, Worse Psychological Profile, and Higher Expectations Than Nonsurgical Counterparts: A Large Cohort Analysis.
Abstract BACKGROUND: Psychological characteristics, such as depression, anxiety or negative illness perception are highly prevalent in patients with several types of OA. It is unclear whether there are differences in the clinical and psychological characteristics of patients with thumb carpometacarpal (CMC-1) osteoarthritis (OA) scheduled for nonsurgical treatment and those with surgical treatment. QUESTIONS/PURPOSES: (1) What are the differences in baseline sociodemographic characteristics and clinical characteristics (including pain, hand function, and health-related quality of life) between patients with t...
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Wouters RM, Vranceanu AM, Slijper HP, Vermeulen GM, van der Oest MJW, Selles RW, Porsius JT, Hand-Wrist Study Group Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Patients With Thumb-base Osteoarthritis Scheduled for Surgery Have More Symptoms, Worse Psychological Profile, and Higher Expectations Than Nonsurgical Counterparts: A Large Cohort Analysis.
CORR Insights®: Patients With Thumb-base Osteoarthritis Scheduled for Surgery Have More Symptoms, Worse Psychological Profile, and Higher Expectations Than Nonsurgical Counterparts: A Large Cohort Analysis. Clin Orthop Relat Res. 2019 Dec;477(12):2747-2749 Authors: McKee D PMID: 31764345 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: McKee D Tags: Clin Orthop Relat Res Source Type: research

Which Psychological Variables Are Associated With Pain and Function Before Surgery for de Quervain's Tenosynovitis? A Cross-sectional Study.
Abstract BACKGROUND: Depression, anxiety, and pain catastrophizing have been associated with worse pain and function in studies of patients with de Quervain's tenosynovitis. Illness perceptions are the patient's thoughts and feelings about their illness. More negative perceptions of the illness such as the illness having a long duration or serious consequences are associated with worse physical function in patients with hand osteoarthritis. It is currently unknown whether these psychological factors play a similar role in de Quervain's. We chose to study patients who have tried nonoperative management and have cho...
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Blackburn J, van der Oest MJW, Selles RW, Chen NC, Feitz R, Vranceanu AM, Porsius JT Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Which Psychological Variables Are Associated With Pain and Function Before Surgery for de Quervain's Tenosynovitis? A Cross-sectional Study.
CORR Insights®: Which Psychological Variables Are Associated With Pain and Function Before Surgery for de Quervain's Tenosynovitis? A Cross-sectional Study. Clin Orthop Relat Res. 2019 Dec;477(12):2759-2760 Authors: Ring D PMID: 31764347 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Ring D Tags: Clin Orthop Relat Res Source Type: research

Patient Position Is Related to the Risk of Neurovascular Injury in Clavicular Plating: A Cadaveric Study.
Abstract BACKGROUND: Fixation of clavicle shaft fractures with a plate and screws can endanger the neurovascular structures if proper care is not taken. Although prior studies have looked at the risk of clavicular plates and screws (for example, length and positions) to vulnerable neurovascular structures (such as the subclavian vein, subclavian artery, and brachial plexus) in the supine position, no studies to our knowledge have compared these distances in the beach chair position. QUESTIONS/PURPOSES: (1) In superior and anteroinferior plating of midclavicle fractures, which screw tips in a typical clavicular ...
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Chuaychoosakoon C, Suwanno P, Boonriong T, Suwannaphisit S, Klabklay P, Parinyakhup W, Maliwankul K, Duangnumsawang Y, Tangtrakulwanich B Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Patient Position Is Related to the Risk of Neurovascular Injury in Clavicular Plating: A Cadaveric Study.
CORR Insights®: Patient Position Is Related to the Risk of Neurovascular Injury in Clavicular Plating: A Cadaveric Study. Clin Orthop Relat Res. 2019 Dec;477(12):2769-2771 Authors: Hawi N PMID: 31764349 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Hawi N Tags: Clin Orthop Relat Res Source Type: research

Partially Melted Ti6Al4V Particles Increase Bacterial Adhesion and Inhibit Osteogenic Activity on 3D-printed Implants: An In Vitro Study.
Abstract BACKGROUND: A porous Ti6Al4V implant that is manufactured using selective laser melting (SLM) has broad potential applications in the field of orthopaedic implants. The pore structure of the SLM porous Ti6Al4V implant allows for cell migration and osteogenic differentiation, which is favorable for bone ingrowth and osseointegration. However, it is unclear whether the pore structure and partially melted Ti6Al4V particles on a SLM porous Ti6Al4V implant will increase bacterial adhesion and, perhaps, the risk of implant-related infection. QUESTIONS/PURPOSES: (1) Is there more bacterial adhesion and colo...
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Xie K, Guo Y, Zhao S, Wang L, Wu J, Tan J, Yang Y, Wu W, Jiang W, Hao Y Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Partially Melted Ti6Al4V Particles Increase Bacterial Adhesion and Inhibit Osteogenic Activity on 3D-printed Implants: An In Vitro Study.
CORR Insights®: Partially Melted Ti6Al4V Particles Increase Bacterial Adhesion and Inhibit Osteogenic Activity on 3D-printed Implants: An In Vitro Study. Clin Orthop Relat Res. 2019 Dec;477(12):2783 Authors: Garino JP PMID: 31764351 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Garino JP Tags: Clin Orthop Relat Res Source Type: research

Intra-articular Injection of Chloramphenicol Reduces Articular Cartilage Degeneration in a Rabbit Model of Osteoarthritis.
CONCLUSIONS: Chloramphenicol reduced the severity of cartilage degradation in a type II collagen-induced rabbit model of OA, which may be related to induction of autophagy and inhibition of MMP-13 and IL-6. CLINICAL RELEVANCE: Our study suggests that an intra-articular injection of chloramphenicol may reduce degeneration of articular cartilage and that induction of autophagy may be a method for treating OA. The animal model we used was type II collagen-induced OA, which was different from idiopathic OA and post-traumatic OA. Therefore, we need to use other types of OA models (idiopathic OA or a surgically induced OA m...
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Wu X, Cai Y, Lu S, Xu K, Shi X, Yang L, Huang Z, Xu P Tags: Clin Orthop Relat Res Source Type: research

Classifications in Brief: The Spinal Instability Neoplastic Score.
PMID: 31764353 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Murtaza H, Sullivan CW Tags: Clin Orthop Relat Res Source Type: research

Letter to the Editor: Not the Last Word: Prizes for Cures.
PMID: 31764354 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: O'Keefe RJ Tags: Clin Orthop Relat Res Source Type: research

Reply to the Letter to the Editor: Not the Last Word: Prizes for Cures.
PMID: 31764355 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Bernstein J Tags: Clin Orthop Relat Res Source Type: research

Letter to the Editor: Editorial: Beware of Studies Claiming that Social Factors are "Independently Associated" with Biological Complications of Surgery.
Letter to the Editor: Editorial: Beware of Studies Claiming that Social Factors are "Independently Associated" with Biological Complications of Surgery. Clin Orthop Relat Res. 2019 Dec;477(12):2807-2809 Authors: Simkin J, Bronstone A, Chapple A, Clement RC, Cohen-Rosenblum A, Czarny-Ratajczak M, Dasa V, Hilliard C, King A, Krause P, Marrero L, Maupin R, Mix K, Ronis MJ, Sammarco MC, Trapido EJ, Zura R, Steen RG PMID: 31764356 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Simkin J, Bronstone A, Chapple A, Clement RC, Cohen-Rosenblum A, Czarny-Ratajczak M, Dasa V, Hilliard C, King A, Krause P, Marrero L, Maupin R, Mix K, Ronis MJ, Sammarco MC, Trapido EJ, Zura R, Steen RG Tags: Clin Orthop Relat Res Source Type: research

Reply to the Letter to the Editor: Editorial: Beware of Studies Claiming that Social Factors are "Independently Associated" with Biological Complications of Surgery.
Reply to the Letter to the Editor: Editorial: Beware of Studies Claiming that Social Factors are "Independently Associated" with Biological Complications of Surgery. Clin Orthop Relat Res. 2019 Dec;477(12):2810-2811 Authors: Leopold SS PMID: 31764357 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Leopold SS Tags: Clin Orthop Relat Res Source Type: research

Letter to the Editor: Editorial: What Do You Say When a Patient Says Thank You?
PMID: 31764358 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 27, 2019 Category: Orthopaedics Authors: Pitto RP Tags: Clin Orthop Relat Res Source Type: research

What Proportion of Orthopaedic Surgery Residency Programs Have Accessible Parental Leave Policies, and How Generous are They?
CONCLUSIONS: Although 91% of programs meet the ACGME requirement of written parental leave policies, current parental leave policies in orthopaedic surgery are not easily accessible for prospective residents, and they do not provide clear compensation and length of leave information. Only 3% (5 of 166) of orthopaedic surgery residency programs had a clearly stated leave policy accessible on the program's website. Substantial improvements would be gained if every orthopaedic residency program clearly outlined the parental leave policy on their residency program website, including compensation and length of leave, particular...
Source: Clinical Orthopaedics and Related Research - November 21, 2019 Category: Orthopaedics Authors: Siljander BR, Van Nortwick SS, Flakne JC, Van Heest AE, Bohn DC Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: What Is the Normal Ulnar Bow in Adult Patients?
CORR Insights®: What Is the Normal Ulnar Bow in Adult Patients? Clin Orthop Relat Res. 2019 Nov 19;: Authors: Nolan BM PMID: 31764313 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 19, 2019 Category: Orthopaedics Authors: Nolan BM Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Is Delayed Time to Surgery Associated with Increased Short-term Complications in Patients with Pathologic Hip Fractures?
CORR Insights®: Is Delayed Time to Surgery Associated with Increased Short-term Complications in Patients with Pathologic Hip Fractures? Clin Orthop Relat Res. 2019 Nov 19;: Authors: Ghert M PMID: 31764314 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 19, 2019 Category: Orthopaedics Authors: Ghert M Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Women Are at Higher Risk for Concussions Due to Ball or Equipment Contact in Soccer and Lacrosse.
CORR Insights®: Women Are at Higher Risk for Concussions Due to Ball or Equipment Contact in Soccer and Lacrosse. Clin Orthop Relat Res. 2019 Nov 19;: Authors: Blasier RD PMID: 31764315 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 19, 2019 Category: Orthopaedics Authors: Blasier RD Tags: Clin Orthop Relat Res Source Type: research