Are Limb-sparing Surgical Resections Comparable to Amputation for Patients With Pelvic Chondrosarcoma? A Case-control, Propensity Score-matched Analysis of the National Cancer Database.
Abstract BACKGROUND: Chondrosarcoma is the second most frequent primary sarcoma of bone and frequently occurs in the pelvis. Surgical resection is the primary treatment with the two main operative modalities being limb-sparing resection and amputation. Contemporary management has trended toward limb-sparing procedures; however, whether this approach has an adverse effect on long-term survival is unclear. QUESTIONS/PURPOSES: (1) What are the 5- and 10-year survival rates after limb-sparing surgery and amputation? (2) What factors are associated with survival after contemporary surgical management of pelvic cho...
Source: Clinical Orthopaedics and Related Research - February 16, 2019 Category: Orthopaedics Authors: Kim CY, Collier CD, Liu RW, Getty PJ Tags: Clin Orthop Relat Res Source Type: research

What Pain Levels Do TSA Patients Experience When Given a Long-acting Nerve Block and Multimodal Analgesia?
CONCLUSIONS: Clinicians using this protocol, which combines a long-acting, single-injection nerve block with multimodal analgesia, can inform TSA patients that their postoperative pain will likely be less than their preoperative pain, and that on average they will stop using opioids after 7 days. Future research could investigate what the individual components of this protocol contribute. Larger cohort studies or registries would document the incidence of rare complications. Randomized controlled trials could directly compare analgesic effectiveness and cost-benefits for this protocol versus alternative strategies, such as...
Source: Clinical Orthopaedics and Related Research - February 16, 2019 Category: Orthopaedics Authors: YaDeau JT, Dines DM, Liu SS, Gordon MA, Goytizolo EA, Lin Y, Schweitzer AA, Fields KG, Gulotta LV Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: What Pain Levels Do TSA Patients Experience When Given a Long-acting Nerve Block and Multimodal Analgesia?
CORR Insights®: What Pain Levels Do TSA Patients Experience When Given a Long-acting Nerve Block and Multimodal Analgesia? Clin Orthop Relat Res. 2019 Mar;477(3):633-634 Authors: Namdari S PMID: 30762695 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - February 16, 2019 Category: Orthopaedics Authors: Namdari S Tags: Clin Orthop Relat Res Source Type: research

Can Patients Forecast Their Postoperative Disability and Pain?
Abstract BACKGROUND: Forecasting is a construct in which experiences and beliefs inform a projection of future outcomes. Current efforts to predict postoperative patient-reported outcome measures such as risk-stratifying models, focus on studying patient, surgeon, or facility variables without considering the mindset of the patient. There is no evidence assessing the association of a patient's forecasted postoperative disability with realized postoperative disability. Patient-forecasted disability could potentially be used as a tool to predict postoperative disability. QUESTIONS/PURPOSES: (1) Do patient-forec...
Source: Clinical Orthopaedics and Related Research - February 16, 2019 Category: Orthopaedics Authors: Alokozai A, Eppler SL, Lu LY, Sheikholeslami N, Kamal RN Tags: Clin Orthop Relat Res Source Type: research

Erratum to: Does Surgery Reduce the Risk of Complications Among Patients with Multiple Rib Fractures? A Meta-analysis.
PMID: 30762697 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - February 16, 2019 Category: Orthopaedics Authors: Liang YS, Yu KC, Wong CS, Kao Y, Tiong TY, Tam KW Tags: Clin Orthop Relat Res Source Type: research

Erratum to: The 2018 Otto Aufranc Award: How Does Genome-wide Variation Affect Osteolysis Risk After THA?
PMID: 30762698 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - February 16, 2019 Category: Orthopaedics Authors: MacInnes SJ, Hatzikotoulas K, Fenstad AM, Shah K, Southam L, Tachmazidou I, Hallan G, Dale H, Panoutsopoulou K, Furnes O, Zeggini E, Wilkinson JM Tags: Clin Orthop Relat Res Source Type: research

Guest Editorial: Is There Value in Value-based Health Care?
PMID: 30664042 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 23, 2019 Category: Orthopaedics Authors: Manner PA Tags: Clin Orthop Relat Res Source Type: research

Editor's Spotlight/Take 5-2018 John Charnley Award: Analysis of US Hip Replacement Bundled Payments: Physician-initiated Episodes Outperform Hospital-initiated Episodes.
PMID: 30664043 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 23, 2019 Category: Orthopaedics Authors: Manner PA Tags: Clin Orthop Relat Res Source Type: research

When Do Patients Return to Previous Daily Activity After Arthroscopic Rotator Cuff Repair?
CONCLUSIONS: It took patients an average of 14 months to recover their daily motion after surgery. Tear size and retear affected only the recovery period of high-level motion activities and sports/leisure. This study was believed to serve as a guideline to inform patients about functional recovery after arthroscopic rotator cuff repair. LEVEL OF EVIDENCE: Level III, therapeutic study. PMID: 30664044 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 23, 2019 Category: Orthopaedics Authors: Kim HJ, Kim JY, Rhee YG Tags: Clin Orthop Relat Res Source Type: research

2018 John Charnley Award: Analysis of US Hip Replacement Bundled Payments: Physician-initiated Episodes Outperform Hospital-initiated Episodes.
This study seeks to quantify BPCI initiative outcomes for THA and to determine the optimal party (for example, hospital versus physician group practice [PGP]) to manage the program. QUESTIONS/PURPOSES: (1) Is BPCI associated with lower 90-day payments, readmissions, or mortality for elective THA? (2) Is there a difference in 90-day payments, readmissions, or mortality between episodes initiated by PGPs and episodes initiated by hospitals for elective THA? (3) Is BPCI associated with reduced total Elixhauser comorbidity index or age for elective THA? METHODS: We performed a retrospective analysis on the CMS Limite...
Source: Clinical Orthopaedics and Related Research - January 23, 2019 Category: Orthopaedics Authors: Murphy WS, Siddiqi A, Cheng T, Lin B, Terry D, Talmo CT, Murphy SB Tags: Clin Orthop Relat Res Source Type: research

Patients With Chronic Obstructive Pulmonary Disease Are at Higher Risk for Pneumonia, Septic Shock, and Blood Transfusions After Total Shoulder Arthroplasty.
CONCLUSIONS: In light of the increased risk of these serious complications, surgeons should have a lower threshold of suspicion for infection in patients with COPD after TSA so that adequate measures can be taken before developing severe infectious complications including pneumonia and septic shock. Surgeons may also consider administering tranexamic acid in patients with COPD undergoing TSA to reduce the amount of blood transfusions necessary. Future work through randomized control trials analyzing (1) the effectiveness of more aggressive infection prophylaxis in decreasing the risk of pneumonia/septic shock; and (2) the ...
Source: Clinical Orthopaedics and Related Research - January 23, 2019 Category: Orthopaedics Authors: Lee R, Lee D, Mamidi IS, Probasco WV, Heyer JH, Pandarinath R Tags: Clin Orthop Relat Res Source Type: research

Classifications in Brief: Sanders Classification of Intraarticular Fractures of the Calcaneus.
ian E PMID: 30664605 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 23, 2019 Category: Orthopaedics Authors: Jiménez-Almonte JH, King JD, Luo TD, Aneja A, Moghadamian E Tags: Clin Orthop Relat Res Source Type: research

Differences in Femoral Torsion Among Various Measurement Methods Increase in Hips With Excessive Femoral Torsion.
Abstract BACKGROUND: Correct quantification of femoral torsion is crucial to diagnose torsional deformities, make an indication for surgical treatment, or plan the amount of correction. However, no clear evaluation of different femoral torsion measurement methods for hips with excessive torsion has been performed to date. QUESTIONS/PURPOSES: (1) How does CT-based measurement of femoral torsion differ among five commonly used measurement methods? (2) Do differences in femoral torsion among measurement methods increase in hips with excessive femoral torsion? (3) What is the reliability and reproducibility of ea...
Source: Clinical Orthopaedics and Related Research - January 7, 2019 Category: Orthopaedics Authors: Schmaranzer F, Lerch TD, Siebenrock KA, Tannast M, Steppacher SD Tags: Clin Orthop Relat Res Source Type: research

Can Machine Learning Methods Produce Accurate and Easy-to-use Prediction Models of 30-day Complications and Mortality After Knee or Hip Arthroplasty?
CONCLUSIONS: Moderately accurate predictive models of 30-day mortality and cardiac complications after elective primary TJA were developed as well as internally and externally validated. To our knowledge, these are the most accurate and rigorously validated TJA-specific prediction models currently available (http://med.stanford.edu/s-spire/Resources/clinical-tools-.html). Methods to improve these models, including the addition of nonstandard inputs such as natural language processing of preoperative clinical progress notes or radiographs, should be pursued as should the development and validation of models to predict longe...
Source: Clinical Orthopaedics and Related Research - January 7, 2019 Category: Orthopaedics Authors: Harris AHS, Kuo AC, Weng Y, Trickey AW, Bowe T, Giori NJ Tags: Clin Orthop Relat Res Source Type: research

Outcome Selection and Methodological Quality of Major and Minor Shoulder Surgery Studies: A Scoping Review.
CONCLUSIONS: A wide range of outcome domains and outcome assessment tools are in common use in contemporary trials of patients undergoing elective surgery. Although some diversity is important to allow the assessment of patient populations that may have different goals, the large number of tools in common use may impair the ability of future meta-analyses to pool results effectively or even for systematic reviews to synthesize what is known. The limitations of methodological quality in RCTs may be improved by researchers following standard guidelines and considering the minimum clinically important differences in their tri...
Source: Clinical Orthopaedics and Related Research - January 7, 2019 Category: Orthopaedics Authors: El-Boghdadly K, Abdallah FW, Short A, Vorobeichik L, Memtsoudis SG, Chan VWS Tags: Clin Orthop Relat Res Source Type: research

Pearls: Improving Upon Minimally Invasive Transforaminal Lumbar Interbody Fusion.
PMID: 30624316 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 7, 2019 Category: Orthopaedics Authors: Qureshi S Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: What is the Natural History of the Triangular Fibrocartilage Complex Tear Without Distal Radioulnar Joint Instability?
CORR Insights®: What is the Natural History of the Triangular Fibrocartilage Complex Tear Without Distal Radioulnar Joint Instability? Clin Orthop Relat Res. 2019 Jan 07;: Authors: Huber M PMID: 30624317 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 7, 2019 Category: Orthopaedics Authors: Huber M Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Cam FAI and Smaller Neck Angles Increase Subchondral Bone Stresses During Squatting: A Finite Element Analysis.
CORR Insights®: Cam FAI and Smaller Neck Angles Increase Subchondral Bone Stresses During Squatting: A Finite Element Analysis. Clin Orthop Relat Res. 2019 Jan 07;: Authors: Tannast M PMID: 30624318 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 7, 2019 Category: Orthopaedics Authors: Tannast M Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Translation and Validation of the German New Knee Society Scoring System.
CORR Insights®: Translation and Validation of the German New Knee Society Scoring System. Clin Orthop Relat Res. 2019 Jan 07;: Authors: Kim TK PMID: 30624319 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 7, 2019 Category: Orthopaedics Authors: Kim TK Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Acetabular Labral Tears Are Common in Asymptomatic Contralateral Hips With Femoroacetabular Impingement.
CORR Insights®: Acetabular Labral Tears Are Common in Asymptomatic Contralateral Hips With Femoroacetabular Impingement. Clin Orthop Relat Res. 2019 Jan 07;: Authors: Domb BG PMID: 30624320 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 7, 2019 Category: Orthopaedics Authors: Domb BG Tags: Clin Orthop Relat Res Source Type: research

No Difference Between Low- and Regular-dose Aspirin for Venous Thromboembolism Prophylaxis After THA.
CONCLUSIONS: We found no difference in the incidence of symptomatic VTE after THA with low-dose compared with standard-dose aspirin. In the absence of compelling evidence to the contrary, low-dose aspirin appears to be a reasonable option for VTE prophylaxis in otherwise healthy patients undergoing elective THA. LEVEL OF EVIDENCE: Level III, therapeutic study. PMID: 30624322 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 4, 2019 Category: Orthopaedics Authors: Faour M, Piuzzi NS, Brigati DP, Klika AK, Mont MM, Barsoum WK, Higuera-Rueda C Tags: Clin Orthop Relat Res Source Type: research

What Factors Are Associated With Outcomes Scores After Surgical Treatment Of Ankle Fractures With a Posterior Malleolar Fragment?
Abstract BACKGROUND: Psychosocial factors, such as depression and catastrophic thinking, might account for more disability after various orthopaedic trauma pathologies than range of motion and other impairments. However, little is known about the influence of psychosocial aspects of illness on long-term symptoms and limitations of patients with rotational-type ankle fractures, including a posterior malleolar fragment. Knowledge of the psychosocial factors associated with long-term outcome after operative treatment of trimalleolar ankle fractures might improve recovery. QUESTIONS/PURPOSES: (1) Which factors re...
Source: Clinical Orthopaedics and Related Research - January 4, 2019 Category: Orthopaedics Authors: Meijer DT, Gevers Deynoot BDJ, Stufkens SA, Sierevelt IN, Goslings JC, Kerkhoffs GMMJ, Doornberg JN Tags: Clin Orthop Relat Res Source Type: research

Not the Last Word: Big Data Will Make You Confront Big Ethical Questions-Here's Why.
PMID: 30624324 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 4, 2019 Category: Orthopaedics Authors: Bernstein J Tags: Clin Orthop Relat Res Source Type: research

Editorial: Importance of Validating the Scores We Use to Assess Patients with Musculoskeletal Tumors.
PMID: 30624325 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 4, 2019 Category: Orthopaedics Authors: Leopold SS Tags: Clin Orthop Relat Res Source Type: research

Is Obesity Associated With Increased Risk of Deep Vein Thrombosis or Pulmonary Embolism After Hip and Knee Arthroplasty? A Large Database Study.
Abstract BACKGROUND: Deep venous thrombosis (DVT) and pulmonary embolus (PE) remain an important cause of morbidity and mortality after THA and TKA. Prior recommendations have advocated for more aggressive prophylaxis for patients with obesity, whereas the evidence supporting these recommendations is conflicting and often based on underpowered studies. QUESTIONS/PURPOSES: (1) What is the association between obesity and DVT and PE after primary and revision THA and TKA? (2) Is there a body mass index (BMI) threshold beyond which DVT and PE risk is elevated? METHODS: We reviewed the American College of Sur...
Source: Clinical Orthopaedics and Related Research - January 3, 2019 Category: Orthopaedics Authors: Sloan M, Sheth N, Lee GC Tags: Clin Orthop Relat Res Source Type: research

Editorial: Clinical Orthopaedics and Related Research, The Bone & Joint Journal, The Journal of Orthopaedic Research, and The Journal of Bone and Joint Surgery Will Not Accept Clinical Research Manuscripts Previously Posted to Preprint Servers.
Editorial: Clinical Orthopaedics and Related Research, The Bone & Joint Journal, The Journal of Orthopaedic Research, and The Journal of Bone and Joint Surgery Will Not Accept Clinical Research Manuscripts Previously Posted to Preprint Servers. Clin Orthop Relat Res. 2019 Jan;477(1):1-4 Authors: Leopold SS, Haddad FS, Sandell LJ, Swiontkowski M PMID: 30586061 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - December 28, 2018 Category: Orthopaedics Authors: Leopold SS, Haddad FS, Sandell LJ, Swiontkowski M Tags: Clin Orthop Relat Res Source Type: research

Cochrane in CORR ®: Strategies to Improve Recruitment to Randomised Trials.
Cochrane in CORR®: Strategies to Improve Recruitment to Randomised Trials. Clin Orthop Relat Res. 2019 Jan;477(1):22-27 Authors: Madden K, Bhandari M PMID: 30586062 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - December 28, 2018 Category: Orthopaedics Authors: Madden K, Bhandari M Tags: Clin Orthop Relat Res Source Type: research

On Patient Safety: The Importance of Vaccinations-Avoiding the Mistakes of the Past.
PMID: 30586063 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - December 28, 2018 Category: Orthopaedics Authors: Rickert J Tags: Clin Orthop Relat Res Source Type: research

CORR ® International-Asia-Pacific: Young Physicians Are Fleeing the Asia-Pacific Region.
CORR® International-Asia-Pacific: Young Physicians Are Fleeing the Asia-Pacific Region. Clin Orthop Relat Res. 2019 Jan;477(1):31-34 Authors: Meshram P PMID: 30586064 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - December 28, 2018 Category: Orthopaedics Authors: Meshram P Tags: Clin Orthop Relat Res Source Type: research

Pearls: Giving and Receiving Feedback.
PMID: 30586065 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - December 28, 2018 Category: Orthopaedics Authors: Emory CL Tags: Clin Orthop Relat Res Source Type: research

Erratum to: Socioeconomic Status Influences Functional Severity of Untreated Cerebral Palsy in Nepal: A Prospective Analysis and Systematic Review.
PMID: 30586066 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - December 28, 2018 Category: Orthopaedics Authors: LeBrun DG, Banskota B, Banskota AK, Rajbhandari T, Baldwin KD, Spiegel DA Tags: Clin Orthop Relat Res Source Type: research

Adverse Childhood Experiences Are Not Associated With Patient-reported Outcome Measures in Patients With Musculoskeletal Illness.
Abstract BACKGROUND: Adverse childhood experiences (ACEs) affect adult mental health and tend to contribute to greater symptoms of depression and more frequent suicide attempts. Given the relationship between symptoms of depression and patient-reported outcomes (PROs), adversity in childhood might be associated with PROs in patients seeking care for musculoskeletal problems, but it is not clear whether in fact there is such an association among patients seeking care in an outpatient, upper extremity orthopaedic practice. QUESTIONS/PURPOSES: (1) Are ACE scores independently associated with variation in physica...
Source: Clinical Orthopaedics and Related Research - December 28, 2018 Category: Orthopaedics Authors: Ottenhoff JSE, Kortlever JTP, Boersma EZ, Laverty DC, Ring D, Driscoll MD Tags: Clin Orthop Relat Res Source Type: research

Classifications in Brief: The Russell-Taylor Classification of Subtrochanteric Hip Fracture.
PMID: 30586343 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - December 28, 2018 Category: Orthopaedics Authors: Rizkalla JM, Nimmons SJB, Jones AL Tags: Clin Orthop Relat Res Source Type: research

A Day at the Office: Dynamic Employee Engagement Can Reduce Your Private Practice's Overhead Expenses.
PMID: 30589652 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - December 26, 2018 Category: Orthopaedics Authors: Lundy DW Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Do Postoperative Results Differ in a Randomized Trial Between a Direct Anterior and a Direct Lateral Approach in THA?
CORR Insights®: Do Postoperative Results Differ in a Randomized Trial Between a Direct Anterior and a Direct Lateral Approach in THA? Clin Orthop Relat Res. 2018 Dec 19;: Authors: Drew JM PMID: 30575615 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - December 19, 2018 Category: Orthopaedics Authors: Drew JM Tags: Clin Orthop Relat Res Source Type: research

What Is the Prevalence of Cam Deformity After Prophylactic Pinning of the Contralateral Asymptomatic Hip in Unilateral Slipped Capital Femoral Epiphysis? A 10-year Minimum Followup Study.
Abstract BACKGROUND: Prophylactic pinning of the asymptomatic and normal-appearing contralateral hip in patients with unilateral slipped capital femoral epiphysis (SCFE) remains controversial. Understanding the minimal 10-year clinical, functional, and radiographic outcomes of the contralateral asymptomatic hip in unilateral SCFE may be helpful in the decision regarding whether the benefits associated with potentially preventing a SCFE are outweighed by the risk of additional surgery. QUESTIONS/PURPOSES: Among patients with SCFE treated with prophylactic pinning of the asymptomatic and contralateral hip, we s...
Source: Clinical Orthopaedics and Related Research - December 13, 2018 Category: Orthopaedics Authors: Lerch TD, Novais EN, Schmaranzer F, Ziebarth K, Steppacher SD, Tannast M, Siebenrock KA Tags: Clin Orthop Relat Res Source Type: research

Is There a Force Target That Predicts Early Patient-reported Outcomes After Kinematically Aligned TKA?
CONCLUSIONS: Tibial compartment forces comparable to those reported for the native knee and insufficient sensitivity of the Oxford Knee and WOMAC scores might explain why mechanical alignment force targets were not useful and a force target was not identified for kinematic alignment. Intraoperative sensors may allow surgeons to measure forces very precisely in the operating room, but that level of precision is not called for to achieve a good/excellent result after calipered kinematically aligned TKA, and so its use may simply add expense and time but does not improve the results from the patient's viewpoint. LEVEL OF...
Source: Clinical Orthopaedics and Related Research - December 7, 2018 Category: Orthopaedics Authors: Shelton TJ, Howell SM, Hull ML Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Are Case Volume and Facility Complexity Level Associated With Postoperative Complications After Hip Fracture Surgery in the Veterans Affairs Healthcare System?
CORR Insights®: Are Case Volume and Facility Complexity Level Associated With Postoperative Complications After Hip Fracture Surgery in the Veterans Affairs Healthcare System? Clin Orthop Relat Res. 2018 Dec 07;: Authors: Freedman BA PMID: 30531424 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - December 7, 2018 Category: Orthopaedics Authors: Freedman BA Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: What Is the Adverse Event Profile After Prophylactic Treatment of Femoral Shaft or Distal Femur Metastases?
CORR Insights®: What Is the Adverse Event Profile After Prophylactic Treatment of Femoral Shaft or Distal Femur Metastases? Clin Orthop Relat Res. 2018 Dec;476(12):2389-2391 Authors: Damron TA PMID: 30427312 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 15, 2018 Category: Orthopaedics Authors: Damron TA Tags: Clin Orthop Relat Res Source Type: research

CORR Insights ®: Statistical Methods Dictate the Estimated Impact of Body Mass Index on Major and Minor Complications After Total Joint Arthroplasty.
CORR Insights®: Statistical Methods Dictate the Estimated Impact of Body Mass Index on Major and Minor Complications After Total Joint Arthroplasty. Clin Orthop Relat Res. 2018 Dec;476(12):2430-2431 Authors: Kurmis AP PMID: 30427313 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 15, 2018 Category: Orthopaedics Authors: Kurmis AP Tags: Clin Orthop Relat Res Source Type: research

Wear Particle-induced Priming of the NLRP3 Inflammasome Depends on Adherent Pathogen-associated Molecular Patterns and Their Cognate Toll-like Receptors: An In Vitro Study.
Abstract BACKGROUND: Orthopaedic wear particles activate the NLRP3 inflammasome to produce active interleukin 1β (IL1β). However, the NLRP3 inflammasome must be primed before it can be activated, and it is unknown whether wear particles induce priming. Toll-like receptors (TLRs) are thought to mediate particle bioactivity. It remains controversial whether pathogen-associated molecular patterns (PAMPs) and/or alarmins are responsible for TLR activation by wear particles. QUESTIONS/PURPOSES: (1) Does priming of the NLRP3 inflammasome by wear particles depend on adherent PAMPs? (2) Does priming of the ...
Source: Clinical Orthopaedics and Related Research - November 15, 2018 Category: Orthopaedics Authors: Manzano GW, Fort BP, Dubyak GR, Greenfield EM Tags: Clin Orthop Relat Res Source Type: research

Erratum to: Can a Conical Implant Successfully Address Complex Anatomy in Primary THA? Radiographs and Hip Scores at Early Followup.
PMID: 30427315 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 15, 2018 Category: Orthopaedics Authors: Zhang G, Goodman SB, Maloney WJ, Huddleston JI Tags: Clin Orthop Relat Res Source Type: research

Letter to the Editor: Is There a Cardiotoxicity Associated With Metallic Head Hip Prostheses? A Cohort Study in the French National Health Insurance Databases.
PMID: 30427316 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 15, 2018 Category: Orthopaedics Authors: Matharu GS, Whitehouse MR Tags: Clin Orthop Relat Res Source Type: research

Reply to the Letter to the Editor: Is There a Cardiotoxicity Associated With Metallic Head Hip Prostheses? A Cohort Study in the French National Health Insurance Databases.
PMID: 30427317 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 15, 2018 Category: Orthopaedics Authors: Lassalle M, Colas S, Zureik M, Dray-Spira R Tags: Clin Orthop Relat Res Source Type: research

Letter to the Editor: Editorial: The Nazi Musculoskeletal Experiments-Why Publish an Article About Them in 2018?
PMID: 30427318 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 15, 2018 Category: Orthopaedics Authors: Shi GG Tags: Clin Orthop Relat Res Source Type: research

Letter to the Editor: Nazi Medicine-Part 2: The Downfall of a Profession and Pernkopf's Anatomy Atlas.
PMID: 30427319 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 15, 2018 Category: Orthopaedics Authors: Yee A, Hildebrandt S, Seidelman WE, Mackinnon SE Tags: Clin Orthop Relat Res Source Type: research

Reply to the Letter to the Editor: Nazi Medicine-Part 2: The Downfall of a Profession and Pernkopf's Anatomy Atlas.
PMID: 30427320 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 15, 2018 Category: Orthopaedics Authors: Bagatur E Tags: Clin Orthop Relat Res Source Type: research

Letter to the Editor: Editorial: The Nazi Musculoskeletal Experiments-Why Publish an Article About Them in 2018?
PMID: 30427321 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 15, 2018 Category: Orthopaedics Authors: Winet H Tags: Clin Orthop Relat Res Source Type: research

Clinical Faceoff: Irreparable Rotator Cuff Tears in Young, Active Patients: Tendon Transfer versus Superior Capsular Reconstruction?
PMID: 30422964 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 14, 2018 Category: Orthopaedics Authors: Camp CL, Elhassan B, Dines JS Tags: Clin Orthop Relat Res Source Type: research

Value-based Healthcare: Applying Time-driven Activity-based Costing in Orthopaedics.
PMID: 30422965 [PubMed - in process] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - November 14, 2018 Category: Orthopaedics Authors: Keswani A, Sheikholeslami N, Bozic KJ Tags: Clin Orthop Relat Res Source Type: research