Is Limb Salvage With Microwave-induced Hyperthermia Better Than Amputation for Osteosarcoma of the Distal Tibia?
CONCLUSIONS: We were encouraged to find no early differences in survival, local recurrence, or serious complications between microwave-induced hyperthermia and amputation, and a functional advantage in favor of microwave-induced hyperthermia. However, these findings should be replicated in larger studies with longer mean duration of followup, and in studies that compare microwave-induced hyperthermia with conventional limb-sparing approaches. LEVEL OF EVIDENCE: Level III, therapeutic study. PMID: 28194714 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - February 13, 2017 Category: Orthopaedics Authors: Han K, Dang P, Bian N, Chen X, Yang T, Fan Q, Zhou Y, Zhao T, Wang P Tags: Clin Orthop Relat Res Source Type: research

Does Extracellular DNA Production Vary in Staphylococcal Biofilms Isolated From Infected Implants versus Controls?
Abstract BACKGROUND: Prosthetic implant infections caused by Staphylococcus aureus and epidermidis are major challenges for early diagnosis and treatment owing to biofilm formation on the implant surface. Extracellular DNA (eDNA) is actively excreted from bacterial cells in biofilms, contributing to biofilm stability, and may offer promise in the detection or treatment of such infections. QUESTIONS/PURPOSES: (1) Does DNA structure change during biofilm formation? (2) Are there time-dependent differences in eDNA production during biofilm formation? (3) Is there differential eDNA production between clinical and...
Source: Clinical Orthopaedics and Related Research - February 13, 2017 Category: Orthopaedics Authors: Zatorska B, Groger M, Moser D, Diab-Elschahawi M, Lusignani LS, Presterl E Tags: Clin Orthop Relat Res Source Type: research

Not the Last Word: Unnecessary Surgery Can Never Be Done Well.
PMID: 28181160 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - February 8, 2017 Category: Orthopaedics Authors: Bernstein J Tags: Clin Orthop Relat Res Source Type: research

From Bench to Bedside: Ischemia is Bad … Right?
From Bench to Bedside: Ischemia is Bad … Right? Clin Orthop Relat Res. 2017 Feb 03;: Authors: Potter BK PMID: 28160255 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - February 3, 2017 Category: Orthopaedics Authors: Potter BK Tags: Clin Orthop Relat Res Source Type: research

Matrix Metalloproteases 1 and 3 Promoter Gene Polymorphism Is Associated With Rotator Cuff Tear.
ira Neto AA Abstract BACKGROUND: Studies suggest that the collagen degeneration and disordered arrangement of collagen fibers in rotator cuff tears are associated with an increase in activity of matrix metalloproteases 1 and 3 (MMP-1 and MMP-3), and that MMP activity may be in part genetically mediated. The degree to which this might be clinically relevant in patients with rotator cuff tears has not been well characterized. QUESTIONS/PURPOSES: (1) Is genetic polymorphism of MMP-1 and MMP-3 associated with rotator cuff tears? (2) Are there haplotypes of MMP-1 and MMP-3 correlated with rotator cuff tears? (3) C...
Source: Clinical Orthopaedics and Related Research - February 3, 2017 Category: Orthopaedics Authors: Assunção JH, Godoy-Santos AL, Dos Santos MC, Malavolta EA, Gracitelli ME, Ferreira Neto AA Tags: Clin Orthop Relat Res Source Type: research

Do Mesenchymal Stem Cells Derived From Atypical Lipomatous Tumors Have Greater Differentiation Potency Than Cells From Normal Adipose Tissues?
CONCLUSIONS: MSCs derived from ALT/WDL had higher osteogenic differentiation potency based on ALP staining, which disappeared as Nutlin-3 concentration increased, suggesting that could be caused by amplified MDM2 in ALT/WDL. Future laboratory studies might mechanistically confirm the gene and protein expression, and based on the mechanism of the gap of differentiation potency, if p53 contrast between MSCs in tumor and normal tissue could be stimulated, less-toxic and more-effective differentiation therapy to MSCs in malignancies might be developed. PMID: 28155209 [PubMed - as supplied by publisher] (Source: Clinical O...
Source: Clinical Orthopaedics and Related Research - February 2, 2017 Category: Orthopaedics Authors: Inatani H, Yamamoto N, Hayashi K, Kimura H, Takeuchi A, Miwa S, Higuchi T, Abe K, Taniguchi Y, Yamada S, Asai K, Otsuka T, Tsuchiya H Tags: Clin Orthop Relat Res Source Type: research

CORR Insights( ®): What is the Accuracy of Nuclear Imaging in the Assessment of Periprosthetic Knee Infection? A Meta-analysis.
CORR Insights(®): What is the Accuracy of Nuclear Imaging in the Assessment of Periprosthetic Knee Infection? A Meta-analysis. Clin Orthop Relat Res. 2017 Feb 02;: Authors: Ilchmann T PMID: 28155210 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - February 2, 2017 Category: Orthopaedics Authors: Ilchmann T Tags: Clin Orthop Relat Res Source Type: research

A Day at the Office: Smooth Transitions-Setting Up the Next Phase of a Professional Life.
PMID: 28155211 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - February 2, 2017 Category: Orthopaedics Authors: Lundy DW Tags: Clin Orthop Relat Res Source Type: research

Can Spatiotemporal Fluoride ((18)F(-)) Uptake be Used to Assess Bone Formation in the Tibia? A Longitudinal Study Using PET/CT.
CONCLUSIONS: Observation of the spatiotemporal uptake of (18)F(-) appears to be a promising method to enable the clinician to assess the progress of bone formation in different parts of the bone. Bone uptake which is uneven across the ends of bone that were supposed to heal or very low bone uptake might indicate impaired bone healing where early intervention may then be needed. However, semiquantification of (18)F(-) uptake (SUVmaxDPD), SUVmeanDPD) was ambiguous in showing consistency with the bone-healing progress. LEVEL OF EVIDENCE: Level III, diagnostic study. PMID: 28150226 [PubMed - as supplied by publi...
Source: Clinical Orthopaedics and Related Research - February 1, 2017 Category: Orthopaedics Authors: Lundblad H, Karlsson-Thur C, Maguire GQ, Jonsson C, Noz ME, Zeleznik MP, Weidenhielm L Tags: Clin Orthop Relat Res Source Type: research

Obituary: A Remembrance of Nas S. Eftekhar (1935-2016).
PMID: 28144924 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 31, 2017 Category: Orthopaedics Authors: Macaulay W Tags: Clin Orthop Relat Res Source Type: research

CORR Insights( ®): Does N-terminal Pro-brain Type Natriuretic Peptide Predict Cardiac Complications After Hip Fracture Surgery?
CORR Insights(®): Does N-terminal Pro-brain Type Natriuretic Peptide Predict Cardiac Complications After Hip Fracture Surgery? Clin Orthop Relat Res. 2017 Jan 31;: Authors: Cornell CN PMID: 28144925 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 31, 2017 Category: Orthopaedics Authors: Cornell CN Tags: Clin Orthop Relat Res Source Type: research

Cochrane in CORR ( ®): Decision Aids for People Facing Health Treatment or Screening Decisions.
Cochrane in CORR (®): Decision Aids for People Facing Health Treatment or Screening Decisions. Clin Orthop Relat Res. 2017 Jan 31;: Authors: Madden K, Kleinlugtenbelt YV PMID: 28144926 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 31, 2017 Category: Orthopaedics Authors: Madden K, Kleinlugtenbelt YV Tags: Clin Orthop Relat Res Source Type: research

CORR Insights( ®): No Clinically Important Difference in Knee Scores or Instability Between Transtibial and Inlay Techniques for PCL Reconstruction: A Systematic Review.
CORR Insights(®): No Clinically Important Difference in Knee Scores or Instability Between Transtibial and Inlay Techniques for PCL Reconstruction: A Systematic Review. Clin Orthop Relat Res. 2017 Jan 30;: Authors: Fu FH PMID: 28138919 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 30, 2017 Category: Orthopaedics Authors: Fu FH Tags: Clin Orthop Relat Res Source Type: research

Editorial: The Minimum Clinically Important Difference-The Least We Can Do.
PMID: 28124297 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 25, 2017 Category: Orthopaedics Authors: Leopold SS, Porcher R Tags: Clin Orthop Relat Res Source Type: research

Reply to the Letter to the Editor: Not the Last Word: Safety Alert: One in 200 Knee Replacement Patients Die Within 90 Days of Surgery.
PMID: 28120292 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 24, 2017 Category: Orthopaedics Authors: Bernstein J Tags: Clin Orthop Relat Res Source Type: research

Does the Critical Shoulder Angle Correlate With Rotator Cuff Tear Progression?
CONCLUSIONS: Even with a longitudinal protocol, most radiographs are of insufficient quality for CSA measurement. Although patients with a history of degenerative cuff disease have higher CSA values than control subjects, the difference is small enough that it could be influenced by measurement error in practice; in any case, a difference of the magnitude we observed is likely to be clinically unimportant. The CSA is not correlated with tear size or tear progression, and does not seem to change with time. These results suggest that the CSA is unlikely to be related to rotator cuff disease. LEVEL OF EVIDENCE: Level II,...
Source: Clinical Orthopaedics and Related Research - January 24, 2017 Category: Orthopaedics Authors: Chalmers PN, Salazar D, Steger-May K, Chamberlain AM, Yamaguchi K, Keener JD Tags: Clin Orthop Relat Res Source Type: research

Letter to the Editor: Not the Last Word: Safety Alert: One in 200 Knee Replacement Patients Die Within 90 Days of Surgery.
PMID: 28120294 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 24, 2017 Category: Orthopaedics Authors: Berstock JR, Whitehouse M Tags: Clin Orthop Relat Res Source Type: research

Is There an Association Between Hemoglobin A1C and Deep Postoperative Infection After TKA?
CONCLUSIONS: The risk of deep postoperative infection requiring surgical intervention after TKA in patients with diabetes mellitus increases as the perioperative HbA1c increases. While a threshold HbA1c level of 8.0 mg/dL was identified, it cannot by itself serve as an independent predictor of postoperative infection in patients with diabetes mellitus because its sensitivity is so low. Future studies should determine what other confounders other than an elevated HbA1c level contribute to increased infection risk and whether decreasing HbA1c levels before TKA will decrease the subsequent risk of infection after surgery. ...
Source: Clinical Orthopaedics and Related Research - January 23, 2017 Category: Orthopaedics Authors: Cancienne JM, Werner BC, Browne JA Tags: Clin Orthop Relat Res Source Type: research

Which Clinical and Patient Factors Influence the National Economic Burden of Hospital Readmissions After Total Joint Arthroplasty?
Abstract BACKGROUND: The Affordable Care Act of 2010 advanced the economic model of bundled payments for total joint arthroplasty (TJA), in which hospitals will be financially responsible for readmissions, typically at 90 days after surgery. However, little is known about the financial burden of readmissions and what patient, clinical, and hospital factors drive readmission costs. QUESTIONS/PURPOSES: (1) What is the incidence, payer mix, and demographics of THA and TKA readmissions in the United States? (2) What patient, clinical, and hospital factors are associated with the cost of 30- and 90-day readmi...
Source: Clinical Orthopaedics and Related Research - January 20, 2017 Category: Orthopaedics Authors: Kurtz SM, Lau EC, Ong KL, Adler EM, Kolisek FR, Manley MT Tags: Clin Orthop Relat Res Source Type: research

ArtiFacts: Corporal Robert O. Burkhardt's Right Leg.
PMID: 28105562 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 19, 2017 Category: Orthopaedics Authors: Hawk AJ Tags: Clin Orthop Relat Res Source Type: research

CORR Insights( ®): "Knuckle Cracking": Can Blinded Observers Detect Changes with Physical Examination and Sonography?
CORR Insights(®): "Knuckle Cracking": Can Blinded Observers Detect Changes with Physical Examination and Sonography? Clin Orthop Relat Res. 2017 Jan 19;: Authors: Ebramzadeh E PMID: 28105563 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 19, 2017 Category: Orthopaedics Authors: Ebramzadeh E Tags: Clin Orthop Relat Res Source Type: research

Editor's Spotlight/Take 5: What Does a Shoulder MRI Cost the Consumer?
PMID: 28101754 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 18, 2017 Category: Orthopaedics Authors: Manner PA Tags: Clin Orthop Relat Res Source Type: research

Does N-terminal Pro-brain Type Natriuretic Peptide Predict Cardiac Complications After Hip Fracture Surgery?
Abstract BACKGROUND: Elderly patients with hip fracture are at risk for cardiac complications. N-terminal pro-brain type natriuretic peptide (NT-proBNP) has been shown to predict cardiac complications in surgical patients; however, to our knowledge, only two studies have evaluated the utility of this test in patients with hip fracture. We believe it is important to assess a more accurate cutoff value of NT-proBNP with exclusion of patients with renal failure. QUESTIONS/PURPOSES: To assess the association between preoperative NT-proBNP and cardiac complications after hip fracture surgery. METHODS: We perf...
Source: Clinical Orthopaedics and Related Research - January 18, 2017 Category: Orthopaedics Authors: Ushirozako H, Ohishi T, Fujita T, Suzuki D, Yamamoto K, Banno T, Takase H, Matsuyama Y Tags: Clin Orthop Relat Res Source Type: research

Your Best Life: Dealing with Loss.
PMID: 28101756 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 18, 2017 Category: Orthopaedics Authors: Donegan DJ, Pasternack BG, Kelly JD Tags: Clin Orthop Relat Res Source Type: research

Blended Chitosan Paste for Infection Prevention: Preliminary and Preclinical Evaluations.
Abstract BACKGROUND: Local drug delivery devices offer a promising method for delivering vancomycin and amikacin for musculoskeletal wounds. However, current local delivery devices such as beads and sponges do not necessarily allow for full coverage of a wound surface with eluted antibiotics and do not address the need for reducing the antibiotic diffusion distance to help prevent contamination by bacteria or other microorganisms. We blended chitosan/polyethylene glycol (PEG) pastes/sponges to increase biocompatibility and improve antibiotic coverage within the wound. QUESTIONS/PURPOSES: (1) Are blended chito...
Source: Clinical Orthopaedics and Related Research - January 17, 2017 Category: Orthopaedics Authors: Berretta JM, Jennings JA, Courtney HS, Beenken KE, Smeltzer MS, Haggard WO Tags: Clin Orthop Relat Res Source Type: research

Residency Diary: My Second Year: September and October 2016.
PMID: 28091801 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 13, 2017 Category: Orthopaedics Authors: Friedman LG Tags: Clin Orthop Relat Res Source Type: research

Increased Risk of Revision, Reoperation, and Implant Constraint in TKA After Multiligament Knee Surgery.
Abstract BACKGROUND: The risk of major complications and revision arthroplasty after TKA in patients who previously underwent multiligament knee surgery have been poorly characterized. QUESTIONS/PURPOSES: Is multiligament knee surgery before TKA associated with (1) worse implant survival, (2) increased use of TKA design constraint, (3) a greater risk for major complications, and (4) poorer scores for pain and function compared with similar patients receiving TKA for primary osteoarthritis? METHODS: Fifty-nine TKAs were performed at our institution between 1985 and 2014 in 59 patients (36 men, 23 women; m...
Source: Clinical Orthopaedics and Related Research - January 13, 2017 Category: Orthopaedics Authors: Pancio SI, Sousa PL, Krych AJ, Abdel MP, Levy BA, Dahm DL, Stuart MJ Tags: Clin Orthop Relat Res Source Type: research

Can Multistate Modeling of Local Recurrence, Distant Metastasis, and Death Improve the Prediction of Outcome in Patients With Soft Tissue Sarcomas?
a J Abstract BACKGROUND: Exploration of the complex relationship between prognostic indicators such as tumor grade and size and clinical outcomes such as local recurrence and distant metastasis in patients with cancer is crucial to guide treatment decisions. However, in patients with soft tissue sarcoma, there are many gaps in our understanding of this relationship. Multistate analysis may help us in gaining a comprehensive understanding of risk factor-outcome relationships in soft tissue sarcoma, because this methodology can integrate multiple risk factors and clinical endpoints into a single statistical model. T...
Source: Clinical Orthopaedics and Related Research - January 12, 2017 Category: Orthopaedics Authors: Posch F, Leitner L, Bergovec M, Bezan A, Stotz M, Gerger A, Pichler M, Stöger H, Liegl-Atzwanger B, Leithner A, Szkandera J Tags: Clin Orthop Relat Res Source Type: research

Definitional Differences of 'Outpatient' Versus 'Inpatient' THA and TKA Can Affect Study Outcomes.
CONCLUSIONS: Future THA, TKA, or other investigations on this topic should consistently quantify the term "outpatient" because different definitions, stated status or actual LOS, may lead to different assignments of risk factors for postoperative complications. Accurate data regarding risk factors for complications after total joint arthroplasty are crucial for efforts to reduce length of hospital stay and minimize complications. LEVEL OF EVIDENCE: Level III, therapeutic study. PMID: 28083753 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 12, 2017 Category: Orthopaedics Authors: Bovonratwet P, Webb ML, Ondeck NT, Lukasiewicz AM, Cui JJ, McLynn RP, Grauer JN Tags: Clin Orthop Relat Res Source Type: research

CORR Insights( ®): Phosphatidylcholine Coatings Deliver Local Antimicrobials and Reduce Infection in a Murine Model: A Preliminary Study.
CORR Insights(®): Phosphatidylcholine Coatings Deliver Local Antimicrobials and Reduce Infection in a Murine Model: A Preliminary Study. Clin Orthop Relat Res. 2017 Jan 12;: Authors: Suda AJ PMID: 28083754 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 12, 2017 Category: Orthopaedics Authors: Suda AJ Tags: Clin Orthop Relat Res Source Type: research

High Risk of Readmission in Octogenarians Undergoing Primary Hip Arthroplasty.
Abstract BACKGROUND: As life expectancy increases, more elderly patients with end-stage hip arthritis are electing to undergo primary THA. Octogenarians undergoing THA have more comorbidities than younger patients, but this is not reflected in risk adjustment models for bundled care programs. The burden of care associated with THA in octogenarians has not been well characterized, and doing so may help these value-based programs make adjustments so that this vulnerable patient population does not risk losing access under accountable care models. QUESTIONS/PURPOSES: The purpose of this study was to describe car...
Source: Clinical Orthopaedics and Related Research - January 12, 2017 Category: Orthopaedics Authors: Malkani AL, Dilworth B, Ong K, Baykal D, Lau E, Mackin TN, Lee GC Tags: Clin Orthop Relat Res Source Type: research

CORR Insights( ®): Is There Benefit to Free Over Pedicled Vascularized Grafts in Augmenting Tibial Intercalary Allograft Constructs?
CORR Insights(®): Is There Benefit to Free Over Pedicled Vascularized Grafts in Augmenting Tibial Intercalary Allograft Constructs? Clin Orthop Relat Res. 2017 Jan 11;: Authors: Nicholas RW PMID: 28078635 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 11, 2017 Category: Orthopaedics Authors: Nicholas RW Tags: Clin Orthop Relat Res Source Type: research

CORR Insights( ®): False-positive Cultures After Native Knee Aspiration: True or False.
CORR Insights(®): False-positive Cultures After Native Knee Aspiration: True or False. Clin Orthop Relat Res. 2017 Jan 11;: Authors: Schlatterer D PMID: 28078636 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 11, 2017 Category: Orthopaedics Authors: Schlatterer D Tags: Clin Orthop Relat Res Source Type: research

Editor's Spotlight/Take 5: Lawnmowers Versus Children: The Devastation Continues.
PMID: 28078637 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 11, 2017 Category: Orthopaedics Authors: Dobbs MB Tags: Clin Orthop Relat Res Source Type: research

Is There Variation in Procedural Utilization for Lumbar Spine Disorders Between a Fee-for-Service and Salaried Healthcare System?
Abstract BACKGROUND: Whether compensation for professional services drives the use of those services is an important question that has not been answered in a robust manner. Specifically, there is a growing concern that spine care practitioners may preferentially choose more costly or invasive procedures in a fee-for-service system, irrespective of the underlying lumbar disorder being treated. QUESTIONS/PURPOSES: (1) Were proportions of interbody fusions higher in the fee-for-service setting as opposed to the salaried Department of Defense setting? (2) Were the odds of interbody fusion increased in a fee-for-s...
Source: Clinical Orthopaedics and Related Research - January 10, 2017 Category: Orthopaedics Authors: Schoenfeld AJ, Makanji H, Jiang W, Koehlmoos T, Bono CM, Haider AH Tags: Clin Orthop Relat Res Source Type: research

CORR Insights( ®): Racial Disparities in Above-knee Amputations after TKA: A National Database Study.
CORR Insights(®): Racial Disparities in Above-knee Amputations after TKA: A National Database Study. Clin Orthop Relat Res. 2017 Jan 10;: Authors: Dougherty PJ PMID: 28074439 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 10, 2017 Category: Orthopaedics Authors: Dougherty PJ Tags: Clin Orthop Relat Res Source Type: research

Erratum to: Reoperation After Cervical Disc Arthroplasty Versus Anterior Cervical Discectomy and Fusion: A Meta-analysis.
PMID: 28058626 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 5, 2017 Category: Orthopaedics Authors: Zhong ZM, Zhu SY, Zhuang JS, Wu Q, Chen JT Tags: Clin Orthop Relat Res Source Type: research

Classifications in Brief: R üedi-Allgöwer Classification of Tibial Plafond Fractures.
Classifications in Brief: Rüedi-Allgöwer Classification of Tibial Plafond Fractures. Clin Orthop Relat Res. 2017 Jan 04;: Authors: Luo TD, Eady JM, Aneja A, Miller AN PMID: 28054323 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 4, 2017 Category: Orthopaedics Authors: Luo TD, Eady JM, Aneja A, Miller AN Tags: Clin Orthop Relat Res Source Type: research

CORR Insights( ®): The Femoro-Epiphyseal Acetabular Roof (FEAR) Index: A New Measurement Associated With Instability in Borderline Hip Dysplasia?
CORR Insights(®): The Femoro-Epiphyseal Acetabular Roof (FEAR) Index: A New Measurement Associated With Instability in Borderline Hip Dysplasia? Clin Orthop Relat Res. 2017 Jan 04;: Authors: Martin HD PMID: 28054324 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 4, 2017 Category: Orthopaedics Authors: Martin HD Tags: Clin Orthop Relat Res Source Type: research

Art in Science: Mondino de' Liuzzi: The Restorer of Anatomy.
cci M PMID: 28054325 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 4, 2017 Category: Orthopaedics Authors: Di Matteo B, Tarabella V, Filardo G, Mosca M, Lo Presti M, Viganò A, Tomba P, Marcacci M Tags: Clin Orthop Relat Res Source Type: research

What Is the Timing of General Health Adverse Events That Occur After Total Joint Arthroplasty?
Abstract BACKGROUND: Despite extensive research regarding risk factors for adverse events after total joint arthroplasty (TJA), there are few publications describing the timing at which such adverse events occur. QUESTIONS/PURPOSES: (1) On which postoperative day do certain adverse events occur? (2) What adverse events occur earlier after TKA than after THA? (3) For each adverse event, what proportion occurred after hospital discharge? METHODS: We screened the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) to identify all patients undergoing primary THA and primary...
Source: Clinical Orthopaedics and Related Research - January 4, 2017 Category: Orthopaedics Authors: Bohl DD, Ondeck NT, Basques BA, Levine BR, Grauer JN Tags: Clin Orthop Relat Res Source Type: research

Obesity Epidemic: Is Its Impact on Total Joint Arthroplasty Underestimated? An Analysis of National Trends.
Abstract BACKGROUND: Obesity is a well-established risk factor for total joint arthroplasty (TJA) and a number of complications including prosthetic joint infection. The annual changes in the prevalence of obesity among primary, revision, and infected TJA has not been studied at a national level. Given the higher costs of complications of TJA, it is important to understand the association of obesity with the annual trends of revision and infected TJA. QUESTIONS/PURPOSES: (1) Is the prevalence of obesity increasing among patients undergoing THA/TKA? (2) Is the prevalence of obesity increasing among patients un...
Source: Clinical Orthopaedics and Related Research - January 4, 2017 Category: Orthopaedics Authors: George J, Klika AK, Navale SM, Newman JM, Barsoum WK, Higuera CA Tags: Clin Orthop Relat Res Source Type: research

Erratum to: Role of Interleukin-6 as an Early Marker of Fat Embolism Syndrome: A Clinical Study.
PMID: 28050810 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 3, 2017 Category: Orthopaedics Authors: Prakash S, Sen RK, Tripathy SK, Sen IM, Sharma RR, Sharma S Tags: Clin Orthop Relat Res Source Type: research

CORR Insights( ®): What is the Incidence of Suicide in Patients with Bone and Soft Tissue Cancer?
CORR Insights(®): What is the Incidence of Suicide in Patients with Bone and Soft Tissue Cancer? Clin Orthop Relat Res. 2017 Jan 03;: Authors: Gundle KR PMID: 28050811 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 3, 2017 Category: Orthopaedics Authors: Gundle KR Tags: Clin Orthop Relat Res Source Type: research

Statistics In Brief: Minimum Clinically Important Difference-Availability of Reliable Estimates.
zma C PMID: 28050812 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 3, 2017 Category: Orthopaedics Authors: Maltenfort M, Díaz-Ledezma C Tags: Clin Orthop Relat Res Source Type: research

Editorial: Bringing CORR's Global Readers the Best in Orthopaedic Research from China and Latin America.
PMID: 28050813 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 3, 2017 Category: Orthopaedics Authors: Leopold SS Tags: Clin Orthop Relat Res Source Type: research

What Orthopaedic Operating Room Surfaces Are Contaminated With Bioburden? A Study Using the ATP Bioluminescence Assay.
CONCLUSIONS: ATP bioluminescence is a novel method to measure cleanliness within the orthopaedic OR and can help identify environmental trouble spots that can potentially lead to increased infection rates. Future studies correlating ATP bioluminescence findings with microbiology cultures could add to the clinical utility of this technology. CLINICAL RELEVANCE: Surfaces such as the undersurface of the OR table headboard, Bair Hugger™ buttons, and tourniquet machine buttons should be routinely cleansed as part of an institutional protocol. Although correlation between ATP bioluminescence and clinical infection was...
Source: Clinical Orthopaedics and Related Research - January 3, 2017 Category: Orthopaedics Authors: Richard RD, Bowen TR Tags: Clin Orthop Relat Res Source Type: research

Erratum to: Editorial: CORR ( ®) Will Change to Double-blind Peer Review-What Took Us So Long to Get There?
Erratum to: Editorial: CORR (®) Will Change to Double-blind Peer Review-What Took Us So Long to Get There? Clin Orthop Relat Res. 2017 Jan 03;: Authors: Leopold SS PMID: 28050815 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - January 3, 2017 Category: Orthopaedics Authors: Leopold SS Tags: Clin Orthop Relat Res Source Type: research

"Knuckle Cracking": Can Blinded Observers Detect Changes with Physical Examination and Sonography?
"Knuckle Cracking": Can Blinded Observers Detect Changes with Physical Examination and Sonography? Clin Orthop Relat Res. 2017 Jan 03;: Authors: Boutin RD, Netto AP, Nakamura D, Bateni C, Szabo RM, Cronan M, Foster B, Barfield WR, Seibert JA, Chaudhari AJ Abstract BACKGROUND: Voluntary knuckle cracking is a common habit, with a reported prevalence of 25% to 45%. Habitual knuckle cracking also is a frequent source of questions for physicians, and the largest study to date reported an association with functional hand impairments. QUESTIONS/PURPOSES: (1) When compared with subjects who are...
Source: Clinical Orthopaedics and Related Research - January 3, 2017 Category: Orthopaedics Authors: Boutin RD, Netto AP, Nakamura D, Bateni C, Szabo RM, Cronan M, Foster B, Barfield WR, Seibert JA, Chaudhari AJ Tags: Clin Orthop Relat Res Source Type: research

Phosphatidylcholine Coatings Deliver Local Antimicrobials and Reduce Infection in a Murine Model: A Preliminary Study.
CONCLUSIONS: Phosphatidylcholine coatings elute antimicrobials in vitro under infinite sink conditions for up to 4 days in phosphate-buffered saline and were able to reduce bacterial colonies in a preliminary in vivo model. Turbidity testing with eluate samples containing varying amounts of C2DA and amikacin agrees with previous studies showing synergy between them. CLINICAL RELEVANCE: Used as an adjunctive to systemic therapy, C2DA-loaded phosphatidylcholine coatings have potential value as a prophylactic infection prevention measure. Future studies may include different antibiotics, animal studies with larger sample...
Source: Clinical Orthopaedics and Related Research - January 3, 2017 Category: Orthopaedics Authors: Harris MA, Beenken KE, Smeltzer MS, Haggard WO, Jennings JA Tags: Clin Orthop Relat Res Source Type: research