Establishing Optic Nerve Diameter Threshold Sensitive and Specific for Optic Atrophy Diagnosis
ConclusionONDs are significantly reduced in patients with OA compared with healthy nerves. A threshold OND of ≤2.3 mm is highly sensitive and specific for a diagnosis of OA. OND was not significantly correlated with RNFL thickness, VA, or VFMD. (Source: Clinical Neuroradiology)
Source: Clinical Neuroradiology - January 3, 2024 Category: Neurology Source Type: research
Comparing the Impact of Stenting vs. Medical Therapy for Intracranial Arterial Stenosis
Conclusions and Relevance: There is an increased risk of peri- and post-procedural stroke and death over best medical therapy in patients with symptomatic ICAS who undergo PTAS. Further work is required to refine patient selection and mitigate peri-procedural risks. (Source: Clinical Neuroradiology)
Source: Clinical Neuroradiology - January 3, 2024 Category: Neurology Source Type: research
How Topographic Diffusion-Weighted Imaging Patterns can Predict the Potential Embolic Source
ConclusionThe associations of DWI with different PES have their distinctive characteristics and DWI along with clinical variables may help predict PES in patients with ESUS. (Source: Clinical Neuroradiology)
Source: Clinical Neuroradiology - January 2, 2024 Category: Neurology Source Type: research
Multiparametric Analysis Combining DSC-MR Perfusion and [18F]FET-PET is Superior to a Single Parameter Approach for Differentiation of Progressive Glioma from Radiation Necrosis
ConclusionA multiparametric MRI-PWI and [18F]FET-PET model consisting of TBRmean, rCBVmean and PWI rTTP significantly outperformed the use of rTBRmean alone, which was the best single parameter approach. Secondarily, we firstly report the potential usefulness of PWI rTTP for discrimination of PD from RN in patients with glioma; however, for validation of our findings the prospective studies with larger patient samples are necessary. (Source: Clinical Neuroradiology)
Source: Clinical Neuroradiology - December 29, 2023 Category: Neurology Source Type: research
Pretreatment CTP Collateral Parameters Predict Good Outcomes in Successfully Recanalized Middle Cerebral Artery Distal Medium Vessel Occlusions
ConclusionA CBV index ≥ 0.7 may be independently associated with good clinical outcomes in our cohort of AIS caused by MCA-DMVOs that were successfully treated with MT. Furthermore, a HIR < 0.3 is also associated with good clinical outcomes. This is the first study of which we are aware to identify a CBV index threshold for MCA-DMVOs. (Source: Clinical Neuroradiology)
Source: Clinical Neuroradiology - December 28, 2023 Category: Neurology Source Type: research
Is Neuroradiology Complementary to Histopathology in Central Nervous System Tumors with an Alteration of the BCOR Gene?
(Source: Clinical Neuroradiology)
Source: Clinical Neuroradiology - December 21, 2023 Category: Neurology Source Type: research
Symptomatic Non-stenotic Carotid Disease in Embolic Stroke of Undetermined Source
ConclusionNon-stenotic carotid disease frequently occurs in patients classified as ESUS and is associated with ipsilateral ischemic stroke. Our findings support the role of non-stenotic carotid disease as stroke etiology in ESUS, but further prospective research is needed to prove a causal relationship. (Source: Clinical Neuroradiology)
Source: Clinical Neuroradiology - December 18, 2023 Category: Neurology Source Type: research
Integrity of Clinical Neuroradiological Research
ConclusionExperts in the field have overall high confidence in published clinical neuroradiology research; however, scientific integrity concerns are not negligible, publication bias is a problem and honorary authorship is common. The findings from this survey may help to increase awareness and vigilance among anyone involved in clinical neuroradiological research. (Source: Clinical Neuroradiology)
Source: Clinical Neuroradiology - December 14, 2023 Category: Neurology Source Type: research
Breath-Hold-Triggered BOLD fMRI in Drug-Resistant Nonlesional Focal Epilepsy —A Pilot Study
ConclusionThis represents the first report of bh-fMRI in individuals with epilepsy undergoing presurgical evaluation. We found bh-fMRI to be feasible and safe, with a promising agreement to electroclinical findings. Thus, bh-fMRI may represent a potential modality in the presurgical evaluation of epilepsy. Further studies are needed to establish clinical utility. (Source: Clinical Neuroradiology)
Source: Clinical Neuroradiology - December 11, 2023 Category: Neurology Source Type: research
