SWI/SNF-deficient tumors of the central nervous system: An update
Clin Neuropathol. 2023 Nov 16. doi: 10.5414/NP301594. Online ahead of print.ABSTRACTAtypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant tumor of the central nervous system characterized by biallelic inactivation of SWI/SNF chromatin remodeling complex members SMARCB1/INI1 or (rarely) SMARCA4/BRG1. Most high-grade central nervous system lesions showing loss of nuclear SMARCB1 or SMARCA4 protein expression can indeed be categorized as AT/RT. However, some high-grade lesions have been identified, whose clinical and/or molecular features justify separation from AT/RT. Furthermore, other recently described tumor type...
Source: Clinical Neuropathology - November 16, 2023 Category: Pathology Authors: Martin Hasselblatt Marcel Kool Michael C Fr ühwald Source Type: research
SWI/SNF-deficient tumors of the central nervous system: An update
Clin Neuropathol. 2023 Nov 16. doi: 10.5414/NP301594. Online ahead of print.ABSTRACTAtypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant tumor of the central nervous system characterized by biallelic inactivation of SWI/SNF chromatin remodeling complex members SMARCB1/INI1 or (rarely) SMARCA4/BRG1. Most high-grade central nervous system lesions showing loss of nuclear SMARCB1 or SMARCA4 protein expression can indeed be categorized as AT/RT. However, some high-grade lesions have been identified, whose clinical and/or molecular features justify separation from AT/RT. Furthermore, other recently described tumor type...
Source: Clinical Neuropathology - November 16, 2023 Category: Pathology Authors: Martin Hasselblatt Marcel Kool Michael C Fr ühwald Source Type: research
SWI/SNF-deficient tumors of the central nervous system: An update
Clin Neuropathol. 2023 Nov 16. doi: 10.5414/NP301594. Online ahead of print.ABSTRACTAtypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant tumor of the central nervous system characterized by biallelic inactivation of SWI/SNF chromatin remodeling complex members SMARCB1/INI1 or (rarely) SMARCA4/BRG1. Most high-grade central nervous system lesions showing loss of nuclear SMARCB1 or SMARCA4 protein expression can indeed be categorized as AT/RT. However, some high-grade lesions have been identified, whose clinical and/or molecular features justify separation from AT/RT. Furthermore, other recently described tumor type...
Source: Clinical Neuropathology - November 16, 2023 Category: Pathology Authors: Martin Hasselblatt Marcel Kool Michael C Fr ühwald Source Type: research
SWI/SNF-deficient tumors of the central nervous system: An update
Clin Neuropathol. 2023 Nov 16. doi: 10.5414/NP301594. Online ahead of print.ABSTRACTAtypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant tumor of the central nervous system characterized by biallelic inactivation of SWI/SNF chromatin remodeling complex members SMARCB1/INI1 or (rarely) SMARCA4/BRG1. Most high-grade central nervous system lesions showing loss of nuclear SMARCB1 or SMARCA4 protein expression can indeed be categorized as AT/RT. However, some high-grade lesions have been identified, whose clinical and/or molecular features justify separation from AT/RT. Furthermore, other recently described tumor type...
Source: Clinical Neuropathology - November 16, 2023 Category: Pathology Authors: Martin Hasselblatt Marcel Kool Michael C Fr ühwald Source Type: research
SWI/SNF-deficient tumors of the central nervous system: An update
Clin Neuropathol. 2023 Nov 16. doi: 10.5414/NP301594. Online ahead of print.ABSTRACTAtypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant tumor of the central nervous system characterized by biallelic inactivation of SWI/SNF chromatin remodeling complex members SMARCB1/INI1 or (rarely) SMARCA4/BRG1. Most high-grade central nervous system lesions showing loss of nuclear SMARCB1 or SMARCA4 protein expression can indeed be categorized as AT/RT. However, some high-grade lesions have been identified, whose clinical and/or molecular features justify separation from AT/RT. Furthermore, other recently described tumor type...
Source: Clinical Neuropathology - November 16, 2023 Category: Pathology Authors: Martin Hasselblatt Marcel Kool Michael C Fr ühwald Source Type: research
SWI/SNF-deficient tumors of the central nervous system: An update
Clin Neuropathol. 2023 Nov 16. doi: 10.5414/NP301594. Online ahead of print.ABSTRACTAtypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant tumor of the central nervous system characterized by biallelic inactivation of SWI/SNF chromatin remodeling complex members SMARCB1/INI1 or (rarely) SMARCA4/BRG1. Most high-grade central nervous system lesions showing loss of nuclear SMARCB1 or SMARCA4 protein expression can indeed be categorized as AT/RT. However, some high-grade lesions have been identified, whose clinical and/or molecular features justify separation from AT/RT. Furthermore, other recently described tumor type...
Source: Clinical Neuropathology - November 16, 2023 Category: Pathology Authors: Martin Hasselblatt Marcel Kool Michael C Fr ühwald Source Type: research
SWI/SNF-deficient tumors of the central nervous system: An update
Clin Neuropathol. 2023 Nov 16. doi: 10.5414/NP301594. Online ahead of print.ABSTRACTAtypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant tumor of the central nervous system characterized by biallelic inactivation of SWI/SNF chromatin remodeling complex members SMARCB1/INI1 or (rarely) SMARCA4/BRG1. Most high-grade central nervous system lesions showing loss of nuclear SMARCB1 or SMARCA4 protein expression can indeed be categorized as AT/RT. However, some high-grade lesions have been identified, whose clinical and/or molecular features justify separation from AT/RT. Furthermore, other recently described tumor type...
Source: Clinical Neuropathology - November 16, 2023 Category: Pathology Authors: Martin Hasselblatt Marcel Kool Michael C Fr ühwald Source Type: research
SWI/SNF-deficient tumors of the central nervous system: An update
Clin Neuropathol. 2023 Nov 16. doi: 10.5414/NP301594. Online ahead of print.ABSTRACTAtypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant tumor of the central nervous system characterized by biallelic inactivation of SWI/SNF chromatin remodeling complex members SMARCB1/INI1 or (rarely) SMARCA4/BRG1. Most high-grade central nervous system lesions showing loss of nuclear SMARCB1 or SMARCA4 protein expression can indeed be categorized as AT/RT. However, some high-grade lesions have been identified, whose clinical and/or molecular features justify separation from AT/RT. Furthermore, other recently described tumor type...
Source: Clinical Neuropathology - November 16, 2023 Category: Pathology Authors: Martin Hasselblatt Marcel Kool Michael C Fr ühwald Source Type: research
SWI/SNF-deficient tumors of the central nervous system: An update
Clin Neuropathol. 2023 Nov 16. doi: 10.5414/NP301594. Online ahead of print.ABSTRACTAtypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant tumor of the central nervous system characterized by biallelic inactivation of SWI/SNF chromatin remodeling complex members SMARCB1/INI1 or (rarely) SMARCA4/BRG1. Most high-grade central nervous system lesions showing loss of nuclear SMARCB1 or SMARCA4 protein expression can indeed be categorized as AT/RT. However, some high-grade lesions have been identified, whose clinical and/or molecular features justify separation from AT/RT. Furthermore, other recently described tumor type...
Source: Clinical Neuropathology - November 16, 2023 Category: Pathology Authors: Martin Hasselblatt Marcel Kool Michael C Fr ühwald Source Type: research
SWI/SNF-deficient tumors of the central nervous system: An update
Clin Neuropathol. 2023 Nov 16. doi: 10.5414/NP301594. Online ahead of print.ABSTRACTAtypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant tumor of the central nervous system characterized by biallelic inactivation of SWI/SNF chromatin remodeling complex members SMARCB1/INI1 or (rarely) SMARCA4/BRG1. Most high-grade central nervous system lesions showing loss of nuclear SMARCB1 or SMARCA4 protein expression can indeed be categorized as AT/RT. However, some high-grade lesions have been identified, whose clinical and/or molecular features justify separation from AT/RT. Furthermore, other recently described tumor type...
Source: Clinical Neuropathology - November 16, 2023 Category: Pathology Authors: Martin Hasselblatt Marcel Kool Michael C Fr ühwald Source Type: research
SWI/SNF-deficient tumors of the central nervous system: An update
Clin Neuropathol. 2023 Nov 16. doi: 10.5414/NP301594. Online ahead of print.ABSTRACTAtypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant tumor of the central nervous system characterized by biallelic inactivation of SWI/SNF chromatin remodeling complex members SMARCB1/INI1 or (rarely) SMARCA4/BRG1. Most high-grade central nervous system lesions showing loss of nuclear SMARCB1 or SMARCA4 protein expression can indeed be categorized as AT/RT. However, some high-grade lesions have been identified, whose clinical and/or molecular features justify separation from AT/RT. Furthermore, other recently described tumor type...
Source: Clinical Neuropathology - November 16, 2023 Category: Pathology Authors: Martin Hasselblatt Marcel Kool Michael C Fr ühwald Source Type: research
SWI/SNF-deficient tumors of the central nervous system: An update
Clin Neuropathol. 2023 Nov 16. doi: 10.5414/NP301594. Online ahead of print.ABSTRACTAtypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant tumor of the central nervous system characterized by biallelic inactivation of SWI/SNF chromatin remodeling complex members SMARCB1/INI1 or (rarely) SMARCA4/BRG1. Most high-grade central nervous system lesions showing loss of nuclear SMARCB1 or SMARCA4 protein expression can indeed be categorized as AT/RT. However, some high-grade lesions have been identified, whose clinical and/or molecular features justify separation from AT/RT. Furthermore, other recently described tumor type...
Source: Clinical Neuropathology - November 16, 2023 Category: Pathology Authors: Martin Hasselblatt Marcel Kool Michael C Fr ühwald Source Type: research
SWI/SNF-deficient tumors of the central nervous system: An update
Clin Neuropathol. 2023 Nov 16. doi: 10.5414/NP301594. Online ahead of print.ABSTRACTAtypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant tumor of the central nervous system characterized by biallelic inactivation of SWI/SNF chromatin remodeling complex members SMARCB1/INI1 or (rarely) SMARCA4/BRG1. Most high-grade central nervous system lesions showing loss of nuclear SMARCB1 or SMARCA4 protein expression can indeed be categorized as AT/RT. However, some high-grade lesions have been identified, whose clinical and/or molecular features justify separation from AT/RT. Furthermore, other recently described tumor type...
Source: Clinical Neuropathology - November 16, 2023 Category: Pathology Authors: Martin Hasselblatt Marcel Kool Michael C Fr ühwald Source Type: research
Clinical Neuropathology 5 & amp; 6, 2023
Clin Neuropathol. 2023 Sep-Oct;42(5):173. doi: 10.5414/NPP42173.NO ABSTRACTPMID:37901951 | DOI:10.5414/NPP42173 (Source: Clinical Neuropathology)
Source: Clinical Neuropathology - October 30, 2023 Category: Pathology Authors: Christian Mawrin Source Type: research
Clinical Neuropathology 5 & amp; 6, 2023
Clin Neuropathol. 2023 Sep-Oct;42(5):173. doi: 10.5414/NPP42173.NO ABSTRACTPMID:37901951 | DOI:10.5414/NPP42173 (Source: Clinical Neuropathology)
Source: Clinical Neuropathology - October 30, 2023 Category: Pathology Authors: Christian Mawrin Source Type: research
