Suprasellar masquerader: Chordoid glioma
CONCLUSION: The rare occurrence as well as the radiological and morphological overlaps in chordoid gliomas make them a true masquerader. Combination of GFAP and TTF-1 in the immunohistochemical panel can be useful in differential diagnosis. Mainstay of treatment is complete surgical excision, with adjuvant radiotherapy becoming increasingly important.PMID:37675487 | DOI:10.5414/NP301577 (Source: Clinical Neuropathology)
Source: Clinical Neuropathology - September 7, 2023 Category: Pathology Authors: Neha Bhardwaj Pravin Salunke Navneet Singla Chirag Ahuja Chandrashekhar Gendle Kirti Gupta Source Type: research

Suprasellar masquerader: Chordoid glioma
CONCLUSION: The rare occurrence as well as the radiological and morphological overlaps in chordoid gliomas make them a true masquerader. Combination of GFAP and TTF-1 in the immunohistochemical panel can be useful in differential diagnosis. Mainstay of treatment is complete surgical excision, with adjuvant radiotherapy becoming increasingly important.PMID:37675487 | DOI:10.5414/NP301577 (Source: Clinical Neuropathology)
Source: Clinical Neuropathology - September 7, 2023 Category: Pathology Authors: Neha Bhardwaj Pravin Salunke Navneet Singla Chirag Ahuja Chandrashekhar Gendle Kirti Gupta Source Type: research

Cerebral amyloid angiopathy: Neuropathological diagnosis, link to Alzheimer's disease and impact on clinics
Clin Neuropathol. 2023 Jul 25. doi: 10.5414/NP301564. Online ahead of print.ABSTRACTCerebral amyloid angiopathy (CAA) is the most frequent cause of lobar hemorrhages in the brains of elderly individuals. It is characterized by the deposition of amyloidogenic proteins in the vessel wall of leptomeningeal and/or intracerebral blood vessels. Different proteins can cause CAA. Most frequently, the amyloid β protein (Aβ) is found to be deposited in CAA and indicates a link to Alzheimer's disease, because Aβ is known to be deposited in amyloid plaques characteristic of Alzheimer's disease. Among other proteins that can also ca...
Source: Clinical Neuropathology - July 25, 2023 Category: Pathology Authors: Dietmar Rudolf Thal Klara Gawor Source Type: research

Cerebral amyloid angiopathy: Neuropathological diagnosis, link to Alzheimer's disease and impact on clinics
Clin Neuropathol. 2023 Jul 25. doi: 10.5414/NP301564. Online ahead of print.ABSTRACTCerebral amyloid angiopathy (CAA) is the most frequent cause of lobar hemorrhages in the brains of elderly individuals. It is characterized by the deposition of amyloidogenic proteins in the vessel wall of leptomeningeal and/or intracerebral blood vessels. Different proteins can cause CAA. Most frequently, the amyloid β protein (Aβ) is found to be deposited in CAA and indicates a link to Alzheimer's disease, because Aβ is known to be deposited in amyloid plaques characteristic of Alzheimer's disease. Among other proteins that can also ca...
Source: Clinical Neuropathology - July 25, 2023 Category: Pathology Authors: Dietmar Rudolf Thal Klara Gawor Source Type: research

Cerebral amyloid angiopathy: Neuropathological diagnosis, link to Alzheimer's disease and impact on clinics
Clin Neuropathol. 2023 Jul 25. doi: 10.5414/NP301564. Online ahead of print.ABSTRACTCerebral amyloid angiopathy (CAA) is the most frequent cause of lobar hemorrhages in the brains of elderly individuals. It is characterized by the deposition of amyloidogenic proteins in the vessel wall of leptomeningeal and/or intracerebral blood vessels. Different proteins can cause CAA. Most frequently, the amyloid β protein (Aβ) is found to be deposited in CAA and indicates a link to Alzheimer's disease, because Aβ is known to be deposited in amyloid plaques characteristic of Alzheimer's disease. Among other proteins that can also ca...
Source: Clinical Neuropathology - July 25, 2023 Category: Pathology Authors: Dietmar Rudolf Thal Klara Gawor Source Type: research

Cerebral amyloid angiopathy: Neuropathological diagnosis, link to Alzheimer's disease and impact on clinics
Clin Neuropathol. 2023 Jul 25. doi: 10.5414/NP301564. Online ahead of print.ABSTRACTCerebral amyloid angiopathy (CAA) is the most frequent cause of lobar hemorrhages in the brains of elderly individuals. It is characterized by the deposition of amyloidogenic proteins in the vessel wall of leptomeningeal and/or intracerebral blood vessels. Different proteins can cause CAA. Most frequently, the amyloid β protein (Aβ) is found to be deposited in CAA and indicates a link to Alzheimer's disease, because Aβ is known to be deposited in amyloid plaques characteristic of Alzheimer's disease. Among other proteins that can also ca...
Source: Clinical Neuropathology - July 25, 2023 Category: Pathology Authors: Dietmar Rudolf Thal Klara Gawor Source Type: research

Cerebral amyloid angiopathy: Neuropathological diagnosis, link to Alzheimer's disease and impact on clinics
Clin Neuropathol. 2023 Jul 25. doi: 10.5414/NP301564. Online ahead of print.ABSTRACTCerebral amyloid angiopathy (CAA) is the most frequent cause of lobar hemorrhages in the brains of elderly individuals. It is characterized by the deposition of amyloidogenic proteins in the vessel wall of leptomeningeal and/or intracerebral blood vessels. Different proteins can cause CAA. Most frequently, the amyloid β protein (Aβ) is found to be deposited in CAA and indicates a link to Alzheimer's disease, because Aβ is known to be deposited in amyloid plaques characteristic of Alzheimer's disease. Among other proteins that can also ca...
Source: Clinical Neuropathology - July 25, 2023 Category: Pathology Authors: Dietmar Rudolf Thal Klara Gawor Source Type: research

Cerebral amyloid angiopathy: Neuropathological diagnosis, link to Alzheimer's disease and impact on clinics
Clin Neuropathol. 2023 Jul 25. doi: 10.5414/NP301564. Online ahead of print.ABSTRACTCerebral amyloid angiopathy (CAA) is the most frequent cause of lobar hemorrhages in the brains of elderly individuals. It is characterized by the deposition of amyloidogenic proteins in the vessel wall of leptomeningeal and/or intracerebral blood vessels. Different proteins can cause CAA. Most frequently, the amyloid β protein (Aβ) is found to be deposited in CAA and indicates a link to Alzheimer's disease, because Aβ is known to be deposited in amyloid plaques characteristic of Alzheimer's disease. Among other proteins that can also ca...
Source: Clinical Neuropathology - July 25, 2023 Category: Pathology Authors: Dietmar Rudolf Thal Klara Gawor Source Type: research

Cerebral amyloid angiopathy: Neuropathological diagnosis, link to Alzheimer's disease and impact on clinics
Clin Neuropathol. 2023 Jul 25. doi: 10.5414/NP301564. Online ahead of print.ABSTRACTCerebral amyloid angiopathy (CAA) is the most frequent cause of lobar hemorrhages in the brains of elderly individuals. It is characterized by the deposition of amyloidogenic proteins in the vessel wall of leptomeningeal and/or intracerebral blood vessels. Different proteins can cause CAA. Most frequently, the amyloid β protein (Aβ) is found to be deposited in CAA and indicates a link to Alzheimer's disease, because Aβ is known to be deposited in amyloid plaques characteristic of Alzheimer's disease. Among other proteins that can also ca...
Source: Clinical Neuropathology - July 25, 2023 Category: Pathology Authors: Dietmar Rudolf Thal Klara Gawor Source Type: research

Cerebral amyloid angiopathy: Neuropathological diagnosis, link to Alzheimer's disease and impact on clinics
Clin Neuropathol. 2023 Jul 25. doi: 10.5414/NP301564. Online ahead of print.ABSTRACTCerebral amyloid angiopathy (CAA) is the most frequent cause of lobar hemorrhages in the brains of elderly individuals. It is characterized by the deposition of amyloidogenic proteins in the vessel wall of leptomeningeal and/or intracerebral blood vessels. Different proteins can cause CAA. Most frequently, the amyloid β protein (Aβ) is found to be deposited in CAA and indicates a link to Alzheimer's disease, because Aβ is known to be deposited in amyloid plaques characteristic of Alzheimer's disease. Among other proteins that can also ca...
Source: Clinical Neuropathology - July 25, 2023 Category: Pathology Authors: Dietmar Rudolf Thal Klara Gawor Source Type: research

Cerebral amyloid angiopathy: Neuropathological diagnosis, link to Alzheimer's disease and impact on clinics
Clin Neuropathol. 2023 Jul 25. doi: 10.5414/NP301564. Online ahead of print.ABSTRACTCerebral amyloid angiopathy (CAA) is the most frequent cause of lobar hemorrhages in the brains of elderly individuals. It is characterized by the deposition of amyloidogenic proteins in the vessel wall of leptomeningeal and/or intracerebral blood vessels. Different proteins can cause CAA. Most frequently, the amyloid β protein (Aβ) is found to be deposited in CAA and indicates a link to Alzheimer's disease, because Aβ is known to be deposited in amyloid plaques characteristic of Alzheimer's disease. Among other proteins that can also ca...
Source: Clinical Neuropathology - July 25, 2023 Category: Pathology Authors: Dietmar Rudolf Thal Klara Gawor Source Type: research

Cerebral amyloid angiopathy: Neuropathological diagnosis, link to Alzheimer's disease and impact on clinics
Clin Neuropathol. 2023 Jul 25. doi: 10.5414/NP301564. Online ahead of print.ABSTRACTCerebral amyloid angiopathy (CAA) is the most frequent cause of lobar hemorrhages in the brains of elderly individuals. It is characterized by the deposition of amyloidogenic proteins in the vessel wall of leptomeningeal and/or intracerebral blood vessels. Different proteins can cause CAA. Most frequently, the amyloid β protein (Aβ) is found to be deposited in CAA and indicates a link to Alzheimer's disease, because Aβ is known to be deposited in amyloid plaques characteristic of Alzheimer's disease. Among other proteins that can also ca...
Source: Clinical Neuropathology - July 25, 2023 Category: Pathology Authors: Dietmar Rudolf Thal Klara Gawor Source Type: research

Cerebral amyloid angiopathy: Neuropathological diagnosis, link to Alzheimer's disease and impact on clinics
Clin Neuropathol. 2023 Jul 25. doi: 10.5414/NP301564. Online ahead of print.ABSTRACTCerebral amyloid angiopathy (CAA) is the most frequent cause of lobar hemorrhages in the brains of elderly individuals. It is characterized by the deposition of amyloidogenic proteins in the vessel wall of leptomeningeal and/or intracerebral blood vessels. Different proteins can cause CAA. Most frequently, the amyloid β protein (Aβ) is found to be deposited in CAA and indicates a link to Alzheimer's disease, because Aβ is known to be deposited in amyloid plaques characteristic of Alzheimer's disease. Among other proteins that can also ca...
Source: Clinical Neuropathology - July 25, 2023 Category: Pathology Authors: Dietmar Rudolf Thal Klara Gawor Source Type: research

Cerebral amyloid angiopathy: Neuropathological diagnosis, link to Alzheimer's disease and impact on clinics
Clin Neuropathol. 2023 Jul 25. doi: 10.5414/NP301564. Online ahead of print.ABSTRACTCerebral amyloid angiopathy (CAA) is the most frequent cause of lobar hemorrhages in the brains of elderly individuals. It is characterized by the deposition of amyloidogenic proteins in the vessel wall of leptomeningeal and/or intracerebral blood vessels. Different proteins can cause CAA. Most frequently, the amyloid β protein (Aβ) is found to be deposited in CAA and indicates a link to Alzheimer's disease, because Aβ is known to be deposited in amyloid plaques characteristic of Alzheimer's disease. Among other proteins that can also ca...
Source: Clinical Neuropathology - July 25, 2023 Category: Pathology Authors: Dietmar Rudolf Thal Klara Gawor Source Type: research

Cerebral amyloid angiopathy: Neuropathological diagnosis, link to Alzheimer's disease and impact on clinics
Clin Neuropathol. 2023 Jul 25. doi: 10.5414/NP301564. Online ahead of print.ABSTRACTCerebral amyloid angiopathy (CAA) is the most frequent cause of lobar hemorrhages in the brains of elderly individuals. It is characterized by the deposition of amyloidogenic proteins in the vessel wall of leptomeningeal and/or intracerebral blood vessels. Different proteins can cause CAA. Most frequently, the amyloid β protein (Aβ) is found to be deposited in CAA and indicates a link to Alzheimer's disease, because Aβ is known to be deposited in amyloid plaques characteristic of Alzheimer's disease. Among other proteins that can also ca...
Source: Clinical Neuropathology - July 25, 2023 Category: Pathology Authors: Dietmar Rudolf Thal Klara Gawor Source Type: research