Gromwell ameliorates glucocorticoid-induced muscle atrophy through the regulation of Akt/mTOR pathway
Muscle atrophy is characterized by decreased muscle mass, function, and strength. Synthetic glucocorticoids, including dexamethasone (Dexa), are commonly used to treat autoimmune diseases. However, prolonged e... (Source: Chinese Medicine)
Source: Chinese Medicine - January 29, 2024 Category: Complementary Medicine Authors: Ahyoung Yoo, Jung-In Kim, Hyunjung Lee, Farida S. Nirmala, Jeong-Hoon Hahm, Hyo Deok Seo, Chang Hwa Jung, Tae Youl Ha and Jiyun Ahn Tags: Research Source Type: research

Decoction regulating phytochemicals ’ micromorphology changes and anti-inflammation activity enhancements originated from herb medicine supermolecules
Mahuang Fuzi decoction (MGF) is composed of three herb medicines that has been clinically used to treat inflammatory diseases for a long history. At present, more and more active phytochemicals ’ aggregations h... (Source: Chinese Medicine)
Source: Chinese Medicine - January 26, 2024 Category: Complementary Medicine Authors: Luping Yang, Xiang Zhang, Zhijia Wang, Xiaoyu Lin, Yaozhi Zhang, Jihui Lu, Linying Wu, Shuchang Yao, Wenguang Jing, Xuemei Huang and Penglong Wang Tags: Research Source Type: research

Zhuifeng Tougu capsules in the treatment of knee osteoarthritis (cold dampness obstruction syndrome): a randomized, double blind, multicenter clinical study
In Traditional Chinese Medicine (TCM) theory, cold dampness obstruction is one of the common syndromes of osteoarthritis. Therefore, in clinical practice, the main treatment methods are to dispel wind, remove ... (Source: Chinese Medicine)
Source: Chinese Medicine - January 25, 2024 Category: Complementary Medicine Authors: Longmei Zhao, Shasha Zhou, SiWei Wang, Rui Wu, Qingliang Meng, Zhenbin Li, Jiangyun Peng, Ying Liu, Min Lu, Ming Li, Caifeng Zhu, Yue Sun, Yanlin He, Yue Jin, Jingyue Gao, Shumin Zhang & hellip; Tags: Research Source Type: research

Ganoderma lucidum polysaccharide ameliorates cholesterol gallstone formation by modulating cholesterol and bile acid metabolism in an FXR-dependent manner
Cholesterol gallstone (CG) disease is a worldwide common disease characterized by cholesterol supersaturation in gallbladder bile. Ganoderma lucidum polysaccharide (GLP) has been shown to possess various benefici... (Source: Chinese Medicine)
Source: Chinese Medicine - January 24, 2024 Category: Complementary Medicine Authors: Dan Huang, Shuang Shen, Qian Zhuang, Xin Ye, Yueqin Qian, Zhixia Dong and Xinjian Wan Tags: Research Source Type: research

Comprehensive review of dibenzocyclooctadiene lignans from the Schisandra genus: anticancer potential, mechanistic insights and future prospects in oncology
Cancer remains one of the leading causes of mortality worldwide. The search for novel and effective anticancer agents has been a significant area of research. Dibenzocyclooctadiene lignans (DBCLS), derived fro... (Source: Chinese Medicine)
Source: Chinese Medicine - January 24, 2024 Category: Complementary Medicine Authors: Karolina Jafernik, Sara Motyka, Daniela Calina, Javad Sharifi-Rad and Agnieszka Szopa Tags: Review Source Type: research

The effects of Chinese proprietary medicine and vaccination on patients with COVID-19: a retrospective study in Macao
COVID-19 is continuing to ravage globally and has resulted in a huge health and financial burden. Chinese proprietary medicines, such as Lianhua Qingwen (LHQW) and Huoxiang Zhengqi (HXZQ) capsules, have been r... (Source: Chinese Medicine)
Source: Chinese Medicine - January 23, 2024 Category: Complementary Medicine Authors: Hui Mo, Man-Fei Zhou, Edmundo Patricio Lopes Lao, Ka-Kei Chan, On-Na Lai, Man-In Ho, Kin-Wa Wong, Ka-Meng Ho, Kin-Tim Sio, Keng-Lam Fong, Yong-Hua Zhao, Seng-Ip Cheang and Iek-Long Lo Tags: Research Source Type: research

Interpreting the efficacy enhancement mechanism of Chinese medicine processing from a biopharmaceutic perspective
Chinese medicine processing (CMP) is a unique pharmaceutical technology that distinguishes it from natural medicines. Current research primarily focuses on changes in chemical components to understand the mech... (Source: Chinese Medicine)
Source: Chinese Medicine - January 18, 2024 Category: Complementary Medicine Authors: Bing Yang, Zhubin Zhang, Jinjing Song, Tianhao Qi, Jingqi Zeng, Liang Feng and Xiaobin Jia Tags: Review Source Type: research

The SIRT1/Nrf2 signaling pathway mediates the anti-pulmonary fibrosis effect of liquiritigenin
At present, the treatment options available for idiopathic pulmonary fibrosis are both limited and often come with severe side effects, emphasizing the pressing requirement for innovative therapeutic alternati... (Source: Chinese Medicine)
Source: Chinese Medicine - January 18, 2024 Category: Complementary Medicine Authors: Qingzhong Hua and Lu Ren Tags: Research Source Type: research

Osteoking promotes bone formation and bone defect repair through ZBP1 –STAT1–PKR–MLKL-mediated necroptosis
Osteoking has been used for fracture therapy with a satisfying clinical efficacy. However, its therapeutic properties and the underlying mechanisms remain elusive. (Source: Chinese Medicine)
Source: Chinese Medicine - January 18, 2024 Category: Complementary Medicine Authors: Suya Zhang, Yudong Liu, Zhaochen Ma, Shuangrong Gao, Lin Chen, Honggang Zhong, Chu Zhang, Tao Li, Weiheng Chen, Yanqiong Zhang and Na Lin Tags: Research Source Type: research

Modified Qing-Zao-Jiu-Fei decoction attenuated pulmonary fibrosis induced by bleomycin in rats via modulating Nrf2/NF- κB and MAPKs pathways
Qing-Zao-Jiu-Fei Decoction (QZJFD) is a famous herbal formula commonly prescribed for the treatment of lung-related diseases in the ancient and modern times. Trichosanthis Fructus (TF) and Fritillariae Thunbergii... (Source: Chinese Medicine)
Source: Chinese Medicine - January 16, 2024 Category: Complementary Medicine Authors: Jia-Qian Zhu, Yuan-Yang Tian, Kam Leung Chan, Zhen Hu, Qing-Qing Xu, Zhi-Xiu Lin and Yan-Fang Xian Tags: Research Source Type: research

Quercetin inhibits caspase-1-dependent macrophage pyroptosis in experimental folic acid nephropathy
The role of pyroptosis in kidney disease is limited and incomplete. Quercetin, a flavonoid compound present in a variety of fruits, vegetables, and plants, has shown antioxidant and anti-inflammatory propertie... (Source: Chinese Medicine)
Source: Chinese Medicine - January 16, 2024 Category: Complementary Medicine Authors: Xianli Gao, Caiyun Guo, Wenjun Li, Yingdong Deng, Wenjun Ning, Jiaqi Xie, Xiaoying Zhan, Youling Fan, Hongtao Chen, Zengping Huang and Jun Zhou Tags: Research Source Type: research

Regulation of polysaccharide in Wu ‐tou decoction on intestinal microflora and pharmacokinetics of small molecular compounds in AIA rats
Wu-tou decoction (WTD), a traditional Chinese medicine prescription, is used to treat rheumatoid arthritis (RA). It works by controlling intestinal flora and its metabolites, which in turn modulates the inflam... (Source: Chinese Medicine)
Source: Chinese Medicine - January 13, 2024 Category: Complementary Medicine Authors: Di Yang, Xiaoxu Cheng, Meiling Fan, Dong Xie, Zhiqiang Liu, Fei Zheng, Yulin Dai, Zifeng Pi and Hao Yue Tags: Research Source Type: research

Effects and mechanisms of Zhizi Chuanxiong herb pair against atherosclerosis: an integration of network pharmacology, molecular docking, and experimental validation
The Zhizi Chuanxiong herb pair (ZCHP) can delay pathological progression of atherosclerosis (AS); however, its pharmacological mechanism remains unclear because of its complex components. The purpose of curren... (Source: Chinese Medicine)
Source: Chinese Medicine - January 11, 2024 Category: Complementary Medicine Authors: Yan Zhang, Yifei Qi, Zijun Jia, Yiming Li, Liqi Wu, Qingbing Zhou and Fengqin Xu Tags: Research Source Type: research

Sanguinarine chloride induces ferroptosis by regulating ROS/BACH1/HMOX1 signaling pathway in prostate cancer
Sanguinarine chloride (S.C) is a benzophenanthrine alkaloid derived from the root of sanguinaria canadensis and other poppy-fumaria species. Studies have reported that S.C exhibits antioxidant, anti-inflammato... (Source: Chinese Medicine)
Source: Chinese Medicine - January 9, 2024 Category: Complementary Medicine Authors: Shanhui Liu, Yan Tao, Shan Wu, Jiawei Lin, Shengjun Fu, Jianzhong Lu, Jing Zhang, Beitang Fu, Erdong Zhang, Jing Xu, Jiaxuan Wang, Lanlan Li, Lei Zhang and Zhiping Wang Tags: Research Source Type: research

Prunella vulgaris polysaccharide inhibits herpes simplex virus infection by blocking TLR-mediated NF- κB activation
Prunella vulgaris polysaccharide extracted by hot water and 30% ethanol precipitation (PVE30) was reported to possess potent antiviral effects against herpes simplex virus (HSV) infection. However, its anti-HSV m... (Source: Chinese Medicine)
Source: Chinese Medicine - January 8, 2024 Category: Complementary Medicine Authors: Xuanlei Zhong, Yibo Zhang, Man Yuan, Lin Xu, Xiaomei Luo, Rong Wu, Zhichao Xi, Yang Li and Hongxi Xu Tags: Research Source Type: research