The combination of Schisandrin C and Luteolin synergistically attenuates hepatitis B virus infection via repressing HBV replication and promoting cGAS-STING pathway activation in macrophages
HBV infection can result in severe liver diseases and is one of the primary causes of liver cell carcinoma-related mortality. Liuwei Wuling tablet (LWWL) is a traditional Chinese medicine formula, with a prote... (Source: Chinese Medicine)
Source: Chinese Medicine - March 18, 2024 Category: Complementary Medicine Authors: Zhixin Wu, Xiaomei Zhao, Ruisheng Li, Xinru Wen, Ye Xiu, Minjuan Long, Junjie Li, Xiuqin Huang, Jincai Wen, Xu Dong, Yingjie Xu, Zhaofang Bai, Xiaoyan Zhan and Xiaohe Xiao Tags: Research Source Type: research
Chinmedomics: a potent tool for the evaluation of traditional Chinese medicine efficacy and identification of its active components
As an important part of medical science, Traditional Chinese Medicine (TCM) attracts much public attention due to its multi-target and multi-pathway characteristics in treating diseases. However, the limitatio... (Source: Chinese Medicine)
Source: Chinese Medicine - March 13, 2024 Category: Complementary Medicine Authors: Mengmeng Wang, Fengting Yin, Ling Kong, Le Yang, Hui Sun, Ye Sun, Guangli Yan, Ying Han and Xijun Wang Tags: Review Source Type: research
Salvianolic acid C attenuates cerebral ischemic injury through inhibiting neuroinflammation via the TLR4-TREM1-NF- κB pathway
Stroke is a leading cause of mortality and disability with ischemic stroke being the most common type of stroke. Salvianolic acid C (SalC), a polyphenolic compound found in Salviae Miltiorrhizae Radix et Rhizoma,... (Source: Chinese Medicine)
Source: Chinese Medicine - March 11, 2024 Category: Complementary Medicine Authors: Wenbo Guo, Xiaojing Xu, Yulin Xiao, Jiatian Zhang, Peiqiang Shen, Xiaoyan Lu and Xiaohui Fan Tags: Research Source Type: research
Cryptotanshinone inhibits PFK-mediated aerobic glycolysis by activating AMPK pathway leading to blockade of cutaneous melanoma
Cutaneous melanoma is a kind of skin malignancy with low morbidity but high mortality. Cryptotanshinone (CPT), an important component of salvia miltiorrhiza has potent anti-tumor activity and also indicates thera... (Source: Chinese Medicine)
Source: Chinese Medicine - March 7, 2024 Category: Complementary Medicine Authors: Qiong Chen, Yang Liu, Yunxuan Zhu, Ziyan Zhu, Jueyao Zou, Yanhong Pan, Yin Lu and Wenxing Chen Tags: Research Source Type: research
A multi-center cross-sectional study of Chinese Herbal Medicine-Drug adverse reactions using active surveillance in Singapore ’s Traditional Chinese Medicine clinics
This study aimed to investigate the rates and causality of patient-reported adverse events (AEs) associated with concomitant Chinese Herbal Medicine (CHM) and Western Medicine prescription drug (WMPD) consumpt... (Source: Chinese Medicine)
Source: Chinese Medicine - March 7, 2024 Category: Complementary Medicine Authors: Chester Yan Jie Ng, Yan Zhao, Ning Wang, Kwan Leung Chia, Chun Huat Teo, William Peh, Pansy Yeo and Linda L. D. Zhong Tags: Research Source Type: research
Electroacupuncture pretreatment mediates sympathetic nerves to alleviate myocardial ischemia –reperfusion injury via CRH neurons in the paraventricular nucleus of the hypothalamus
Myocardial ischemia –reperfusion can further exacerbate myocardial injury and increase the risk of death. Our previous research found that the paraventricular nucleus (PVN) of the hypothalamus plays a crucial r... (Source: Chinese Medicine)
Source: Chinese Medicine - March 6, 2024 Category: Complementary Medicine Authors: Jie Zhou, Bin Zhang, Xiang Zhou, Fan Zhang, Qi Shu, Yan Wu, Hui-Min Chang, Ling Hu, Rong-Lin Cai and Qing Yu Tags: Research Source Type: research
Cayratia albifolia C.L.Li exerts anti-rheumatoid arthritis effect by inhibiting macrophage activation and neutrophil extracellular traps (NETs)
Cayratia albifolia C.L.Li (CAC), commonly known as “Jiao-Mei-Gu” in China, has been extensively utilized by the Dong minority for several millennia to effectively alleviate symptoms associated with autoimmune dis... (Source: Chinese Medicine)
Source: Chinese Medicine - March 5, 2024 Category: Complementary Medicine Authors: Wei Wang, Zai-Qi Zhang, Yi-Chi Zhang, Yi-Qiang Wu, Zhuo Yang, Yong-Zhe Zheng, Jia-Hong Lu, Peng-Fei Tu and Ke-Wu Zeng Tags: Research Source Type: research
Platycodon D protects human nasal epithelial cells from pyroptosis through the Nrf2/HO-1/ROS signaling cascade in chronic rhinosinusitis
Pyroptosis has been demonstrated being closely associated with the inflammatory progression in chronic rhinosinusitis (CRS). However, platycodon D (PLD) has emerged as a key anti-inflammatory mediator in the i... (Source: Chinese Medicine)
Source: Chinese Medicine - March 4, 2024 Category: Complementary Medicine Authors: Ruizhi Wang, Yongchun Wang, He Liu, Jinxiang Zhu, Caishan Fang, Weizhen Xu, Zesheng Lu, Yajie Yan, Weiping He, Yan Ruan and Min Zhou Tags: Research Source Type: research
LanGui tea, an herbal medicine formula, protects against binge alcohol-induced acute liver injury by activating AMPK-NLRP3 signaling
LanGui tea, a traditional Chinese medicine formulation comprising of Gynostemma pentaphyllum (Thunb.) Makino, Cinnamomum cassia (L.) J. Presl, and Ampelopsis grossedentata (Hand-Mazz) W.T. Wang, has yet to have i... (Source: Chinese Medicine)
Source: Chinese Medicine - March 4, 2024 Category: Complementary Medicine Authors: Ming Gu, Yu-jun Chen, Ya-ru Feng and Zhi-peng Tang Tags: Research Source Type: research
Golden bile powder prevents drunkenness and alcohol-induced liver injury in mice via the gut microbiota and metabolic modulation
Drunkenness and alcoholic liver disease (ALD) are critical public health issues associated with significant morbidity and mortality due to chronic overconsumption of alcohol. Traditional remedies, such as bear... (Source: Chinese Medicine)
Source: Chinese Medicine - March 2, 2024 Category: Complementary Medicine Authors: Yarong Wang, Zhenzhuang Zou, Sihua Wang, Airong Ren, Zhaolin Ding, Yingying Li, Yifang Wang, Zhengming Qian, Baolin Bian, Bo Huang, Guiwei Xu and Guozhen Cui Tags: Research Source Type: research
A novel network pharmacology strategy to decode mechanism of Wuling Powder in treating liver cirrhosis
Liver cirrhosis is a chronic liver disease with hepatocyte necrosis and lesion. As one of the TCM formulas Wuling Powder (WLP) is widely used in the treatment of liver cirrhosis. However, it ’s key functional c... (Source: Chinese Medicine)
Source: Chinese Medicine - March 1, 2024 Category: Complementary Medicine Authors: Qinwen Liu, Xiaowei Li, Yi Li, Qian Luo, Qiling Fan, Aiping Lu, Daogang Guan and Jiahui Li Tags: Research Source Type: research
Trachelogenin alleviates osteoarthritis by inhibiting osteoclastogenesis and enhancing chondrocyte survival
Osteoarthritis (OA) is a prevalent global health concern associated with the loss of articular cartilage and subchondral bone. The lack of disease-modifying drugs for OA necessitates the exploration of novel t... (Source: Chinese Medicine)
Source: Chinese Medicine - March 1, 2024 Category: Complementary Medicine Authors: Tao Jiang, Jiahui Zhang, Beite Ruan, Xiaobing Xi, Zhuo Yang, Jianmin Liu, Hongyan Zhao, Xing Xu and Min Jiang Tags: Research Source Type: research
Traditional Chinese Medicine Shi-Bi-Man ameliorates psoriasis via inhibiting IL-23/Th17 axis and CXCL16-mediated endothelial activation
Psoriasis is a chronic inflammatory genetic disease, mainly manifesting in the skin. Conventional therapies, such as glucocorticosteroids and corticosteroids, have adverse effects that limit drug use. Hence, i... (Source: Chinese Medicine)
Source: Chinese Medicine - March 1, 2024 Category: Complementary Medicine Authors: Chenyang Zhang, Xinran Cao, Lixin Zhao, Zitong Ni, Haojie Du, Jiao Qu, Jianxia Zhu, Haiyan Sun, Yang Sun and Zijun Ouyang Tags: Research Source Type: research
Bufei Yishen formula protects the airway epithelial barrier and ameliorates COPD by enhancing autophagy through the Sirt1/AMPK/Foxo3 signaling pathway
In this study, we determined whether BYF protects the airway epithelial barrie... (Source: Chinese Medicine)
Source: Chinese Medicine - February 28, 2024 Category: Complementary Medicine Authors: Lidan Jia, Xuefang Liu, Xinguang Liu, Qingzhou Guan, Yange Tian, Jiansheng Li and Peng Zhao Tags: Research Source Type: research
Determination of ITS1 haplotypes of Fritillariae Cirrhosae Bulbus by amplicon sequencing
Fritillariae Cirrhosae Bulbus is an antitussive and expectorant Chinese medicinal material derived from the dried bulbs of six Fritillaria species. In the 2015 edition of the Chinese Pharmacopoeia, the polymerase... (Source: Chinese Medicine)
Source: Chinese Medicine - February 28, 2024 Category: Complementary Medicine Authors: Hoi-Yan Wu, Ka-Lok Wong, Sean Tsz-Sum Law, Wenyang Nong, Kwun-Tin Chan, Jerome Ho-Lam Hui, Ge Lin, Wing-Han Chan and Pang-Chui Shaw Tags: Research Source Type: research
