The total polyphenolic glycoside extract of Lamiophlomis rotata ameliorates hepatic fibrosis through apoptosis by TGF- β/Smad signaling pathway
Hepatic fibrosis is characterized by the excessive deposition of extracellular matrix (ECM) which is mainly secreted by activated hepatic stellate cells (HSCs). Lamiophlomis rotata (L. rotata) was recorded to tre... (Source: Chinese Medicine)
Source: Chinese Medicine - February 24, 2023 Category: Complementary Medicine Authors: Guoguo Wan, Zhiwei Chen, Lei Lei, Xiaoyu Geng, Yi Zhang, Congwen Yang, Wenfu Cao and Zheng Pan Tags: Research Source Type: research

A review on the effect of garlic on diabetes, BDNF, and VEGF as a potential treatment for diabetic retinopathy
Garlic is one of the favorite herbs in traditional medicine that has been reported to have many medicinal features. The aim of the current study is to review the latest documents on the effect of garlic on dia... (Source: Chinese Medicine)
Source: Chinese Medicine - February 17, 2023 Category: Complementary Medicine Authors: Fatemeh Sanie-Jahromi, Zahra Zia and Mehrdad Afarid Tags: Review Source Type: research

Exploration of the anti-hyperuricemia effect of TongFengTangSan (TFTS) by UPLC-Q-TOF/MS-based non-targeted metabonomics
TongFengTangSan (TFTS) is a commonly used Tibetan prescription for gout treatment. Previously, TFTS (CF) was confirmed to have a significant uric acid-lowering effect. However, the anti-hyperuricemia mechanism... (Source: Chinese Medicine)
Source: Chinese Medicine - February 16, 2023 Category: Complementary Medicine Authors: Zhichao Huang, Wugang Zhang, Qiong An, Yifan Lang, Ye Liu, Huifang Fan and Haifang Chen Tags: Research Source Type: research

Advances in natural product anti-coronavirus research (2002-2022)
COVID-19 is a severe acute respiratory syndrome caused by coronavirus that has triggered acute respiratory infections in countries around the world. In the last 20 years, there have been several outbreaks of c... (Source: Chinese Medicine)
Source: Chinese Medicine - February 13, 2023 Category: Complementary Medicine Authors: Jiaxin Chen and Zuoqi Ding Tags: Review Source Type: research

Identification of histone acetyltransferase genes responsible for cannabinoid synthesis in hemp
Histone acetyltransferases (HATs) play an important role in plant growth and development, stress response, and regulation of secondary metabolite biosynthesis. Hemp (Cannabis sativa L.) is famous for its high ind... (Source: Chinese Medicine)
Source: Chinese Medicine - February 13, 2023 Category: Complementary Medicine Authors: Yufei Cheng, Kang Ning, Yongzhong Chen, Cong Hou, Haibin Yu, Huatao Yu, Shilin Chen, Xiaotong Guo and Linlin Dong Tags: Research Source Type: research

Traditional Chinese medicine for colorectal cancer treatment: potential targets and mechanisms of action
Colorectal cancer (CRC) is a disease with complex pathogenesis, it is prone to metastasis, and its development involves abnormalities in multiple signaling pathways. Surgery, chemotherapy, radiotherapy, target... (Source: Chinese Medicine)
Source: Chinese Medicine - February 13, 2023 Category: Complementary Medicine Authors: Jin-Fang Chen, Shi-Wei Wu, Zi-Man Shi and Bing Hu Tags: Review Source Type: research

Variable importance for projection (VIP) scores for analyzing the contribution of risk factors in severe adverse events to Xiyanping injection
Age and herb-drug combination are risk factors for the severity of Xiyanping injection (XYP) associated adverse events (AEs). (Source: Chinese Medicine)
Source: Chinese Medicine - February 13, 2023 Category: Complementary Medicine Authors: Rui Zheng, Zhao Chen, Zhiyue Guan, Chen Zhao, Herong Cui and Hongcai Shang Tags: Research Source Type: research

Combined with UPLC-Triple-TOF/MS-based plasma lipidomics and molecular pharmacology reveals the mechanisms of schisandrin against Alzheimer ’s disease
Alzheimer ’s disease (AD), a type of neurodegeneration disease, is characterized by Aβ deposition and tangles of nerve fibers. Schisandrin is one of the main components of Fructus Schisandrae Chinensis. Researches... (Source: Chinese Medicine)
Source: Chinese Medicine - February 6, 2023 Category: Complementary Medicine Authors: Tian-tian Zhao, Ying Zhang, Cheng-qin Zhang, Ya-fei Chang, Mei-rong Cui, Yue Sun, Wen-qian Hao, Yu-meng Yan, Shuo Gu, Yao Xie and Bin-bin Wei Tags: Research Source Type: research

Exploring the active components and potential mechanisms of Rosa roxburghii Tratt in treating type 2 diabetes mellitus based on UPLC-Q-exactive Orbitrap/MS and network pharmacology
Type 2 diabetes mellitus (T2DM) is a global disease with growing prevalence that is difficult to cure. Rosa roxburghii Tratt is an edible and medicinal plant, and modern pharmacological studies have shown that it... (Source: Chinese Medicine)
Source: Chinese Medicine - February 6, 2023 Category: Complementary Medicine Authors: Chenxiao Shen, Yu Wang, Hui Zhang, Wei Li, Wenyue Chen, Mingqing Kuang, Yuelin Song and Zhangfeng Zhong Tags: Research Source Type: research

Screening of Q-markers for the wine-steamed Schisandra chinensis decoction pieces in improving allergic asthma
Traditional Chinese medicine (TCM) posits that Chinese medicinal materials can only be clinically used after being processed and prepared into decoction pieces. Schisandra Chinensis Fructus (derived from the d... (Source: Chinese Medicine)
Source: Chinese Medicine - January 30, 2023 Category: Complementary Medicine Authors: Zhongyuan Qu, Yifan Bing, Tianlei Zhang, Yan Zheng, Shuang Wu, Chenfeng Ji, Wenlan Li and Xiang Zou Tags: Research Source Type: research

Gancao Nourishing-Yin decoction combined with methotrexate in treatment of aging CIA mice: a study based on DIA proteomic analysis
Elderly rheumatoid arthritis (ERA) population faces multiple treatment dilemma. Here we aim to investigate if Gancao Nourishing-Yin decoction (GCNY) added to methotrexate (MTX) exhibit better effects in an ERA mi... (Source: Chinese Medicine)
Source: Chinese Medicine - January 28, 2023 Category: Complementary Medicine Authors: Yong Chen, Xing-wang Zhu, Wing-Fu Lai, Yong-pu Liu, Xuan-feng Xu, Li-ming Liu, Yan-juan Chen, Chuan-fu Zhang, Guang-yi Wang, Zhi-qiang Cheng and Dong-zhou Liu Tags: Research Source Type: research

The neuroprotective and neural circuit mechanisms of acupoint stimulation for cognitive impairment
Cognitive impairment is a prevalent neurological disorder that burdens families and the healthcare system. Current conventional therapies for cognitive impairment, such as cholinesterase inhibitors and N-methy... (Source: Chinese Medicine)
Source: Chinese Medicine - January 20, 2023 Category: Complementary Medicine Authors: Zichen Zhang, Liuyi Chen, Yi Guo, Dan Li, Jingyu Zhang, Ling Liu, Wen Fan, Tao Guo, Siru Qin, Yadan Zhao, Zhifang Xu and Zelin Chen Tags: Review Source Type: research

Identification of key pharmacological components and targets for Aidi injection in the treatment of pancreatic cancer by UPLC-MS, network pharmacology, and in vivo experiments
Pancreatic cancer is one of the most lethal cancers worldwide. Aidi injection (ADI) is a representative antitumor medication based on Chinese herbal injection, but its antitumor mechanisms are still poorly und... (Source: Chinese Medicine)
Source: Chinese Medicine - January 14, 2023 Category: Complementary Medicine Authors: Haojia Wang, Zhishan Wu, Xiaotian Fan, Chao Wu, Shan Lu, Libo Geng, Antony Stalin, Yingli Zhu, Fanqin Zhang, Jiaqi Huang, Pengyun Liu, Huiying Li, Leiming You and Jiarui Wu Tags: Research Source Type: research

Two-dimensional code enables visibly mapping herbal medicine chemome: an application in Ganoderma lucidum
Chemical profile provides the pronounced evidence for herbal medicine (HM) authentication; however, the chemome is extremely sophisticated. Fortunately, two-dimensional (2D) code, as a quick response means, is... (Source: Chinese Medicine)
Source: Chinese Medicine - January 12, 2023 Category: Complementary Medicine Authors: Qian Wang, Wenjing Liu, Bo Peng, Xingcheng Gong, Jingjing Shi, Ke Zhang, Bo Li, Pengfei Tu, Jun Li, Jun Jiang, Yunfang Zhao and Yuelin Song Tags: Research Source Type: research

Genetic analysis reveals the inconsistency of amorpha-4,11-diene synthase, a key enzyme in the artemisinin synthesis pathway, in asteraceae
Amorpha-4,11-diene synthase (ADS) is a key enzyme in the artemisinin biosynthetic pathway. ADS promotes the first step of artemisinin synthesis by cyclizing faresyl pyrophosphate to synthesize the sesquiterpen... (Source: Chinese Medicine)
Source: Chinese Medicine - January 11, 2023 Category: Complementary Medicine Authors: Shiyu Chen, Baosheng Liao, Shuai Guo, Xiaofeng Shen, Ying Meng, Yu Liang, Jiang Xu and Shilin Chen Tags: Research Source Type: research