Cyasterone ameliorates sepsis-related acute lung injury via AKT (Ser473)/GSK3 β (Ser9)/Nrf2 pathway
Acute lung injury (ALI) is a severe disease that can lead to acute respiratory distress syndrome (ARDS), characterized by intractable hypoxemia, poor lung compliance, and respiratory failure, severely affectin... (Source: Chinese Medicine)
Source: Chinese Medicine - October 19, 2023 Category: Complementary Medicine Authors: Miao Lin, Weixi Xie, Dayan Xiong, Siyuan Tang, Xiaoting Huang, Lang Deng, Lei Huang, Xiaohua Zhang, Tingting Zhou, Rui Qian, Qian Zeng, Xiaoxue Sang, Yuyang Luo, Qingzhong Hua, Lu Ren and Wei Liu Tags: Research Source Type: research
Modulating activity of PVN neurons prevents atrial fibrillation induced circulation dysfunction by electroacupuncture at BL15
Circulation dysfunction is a major contributing factor to thrombosis in patients with atrial fibrillation (AF) for which effective interventions are lacking. Growing evidence indicates that regulating the para... (Source: Chinese Medicine)
Source: Chinese Medicine - October 17, 2023 Category: Complementary Medicine Authors: Jingya Wang, Qiumei Zhang, Lin Yao, Teng He, Xinyi Chen, Yang Su, Shengxuan Sun, Mengyue Fan, Jinglan Yan, Taiyi Wang, Meng Zhang, Feng Guo, Shiqing Mo, Manqi Lu, Meixia Zou, Liangjie Li & hellip; Tags: Research Source Type: research
Co-delivery of dimeric camptothecin and chlorin e6 via polypeptide-based micelles for chemo-photodynamic synergistic therapy
The integration of photodynamic therapy with a chemical drug-delivery system has displayed great potential in enhancing anticancer therapy. However, the solubility and non-specific biodistribution of both chem... (Source: Chinese Medicine)
Source: Chinese Medicine - October 13, 2023 Category: Complementary Medicine Authors: Zhaopei Guo, Ka Hong Wong, Enze Li, Xingzhi Zhou, Di Jiang, Jiebing Gao and Meiwan Chen Tags: Research Source Type: research
Cordycepin from Cordyceps militaris ameliorates diabetic nephropathy via the miR-193b-5p/MCL-1 axis
Diabetic nephropathy (DN) is a chronic kidney disease that develops in patients with diabetes mellitus. Cordycepin (CRD), a secondary metabolite produced by Cordyceps militaris, has a variety of bioactive propert... (Source: Chinese Medicine)
Source: Chinese Medicine - October 13, 2023 Category: Complementary Medicine Authors: Rong Zheng, Weijie Zhang, Jufang Song, Yifei Zhong and Rong Zhu Tags: Research Source Type: research
A review on the research progress of traditional Chinese medicine with anti-cancer effect targeting ferroptosis
Ferroptosis is a non-apoptotic form of regulated cell death characterized by iron-dependent lipid peroxidation. It can be triggered by various mechanisms, including the glutathione peroxidase 4 (GPX4)-glutathi... (Source: Chinese Medicine)
Source: Chinese Medicine - October 13, 2023 Category: Complementary Medicine Authors: Longyan Wang, Huiming Huang, Xingxing Li, Lishan Ouyang, Xuejiao Wei, Jinxin Xie, Dongxiao Liu, Peng Tan and Zhongdong Hu Tags: Review Source Type: research
Fermented cordyceps powder alleviates silica-induced pulmonary inflammation and fibrosis in rats by regulating the Th immune response
Silicosis is an important occupational disease caused by inhalation of free silica and is characterized by persistent pulmonary inflammation, subsequent fibrosis and lung dysfunction. Until now, there has been... (Source: Chinese Medicine)
Source: Chinese Medicine - October 12, 2023 Category: Complementary Medicine Authors: Shuangshuang Pu, Zhifeng Yang, Xiaofeng Zhang, Ming Li, Na Han, Xiaohan Yang, Jin He, Gongchang Yu, Xiangjing Meng, Qiang Jia and Hua Shao Tags: Research Source Type: research
Jin-Gui-Shen-Qi Wan ameliorates diabetic retinopathy by inhibiting apoptosis of retinal ganglion cells through the Akt/HIF-1 α pathway
Jin-Gui-Shen-Qi Wan (JGSQ) has been used in China for thousands of years to treat various ailments, including frequent urination, blurred vision, and soreness in the waist and knees. It has traditional therape... (Source: Chinese Medicine)
Source: Chinese Medicine - October 12, 2023 Category: Complementary Medicine Authors: Dan Liang, Yulin Qi, Lu Liu, Zhaoxia Chen, Shiyun Tang, Jianyuan Tang and Nianzhi Chen Tags: Research Source Type: research
Validation of the Cantonese version of the Traditional Chinese Medicine (TCM) Body constitution Questionnaire in elderly people
The Traditional Chinese Medicine (TCM) Body Constitution Questionnaire (For Elderly People) (TCMECQ) is a patient-reported outcome questionnaire developed in Mandarin in 2013 to differentiate the body constitu... (Source: Chinese Medicine)
Source: Chinese Medicine - October 11, 2023 Category: Complementary Medicine Authors: Yiu Lin Wong, Jialing Zhang, Xingyao Wu, Suet Yee Wong, Zheng Wang, Linda L. D. Zhong and Zhaoxiang Bian Tags: Research Source Type: research
Isoforskolin modulates AQP4-SPP1-PIK3C3 related pathway for chronic obstructive pulmonary disease via cAMP signaling
Cyclic adenosine monophosphate (cAMP) levels are directly activated by adenylate cyclase (AC) and play an anti-inflammatory role in chronic obstructive pulmonary disease (COPD). Previously, we have shown that ... (Source: Chinese Medicine)
Source: Chinese Medicine - October 10, 2023 Category: Complementary Medicine Authors: Haochang Lin, Sha Cheng, Songye Yang, Qian Zhang, Lueli Wang, Jiangya Li, Xinyue Zhang, Liju Liang, Xiaoqian Zhou, Furong Yang, Jingfeng Song, Xue Cao, Weimin Yang and Zhiying Weng Tags: Research Source Type: research
Thermal treatment enhances the resisting exercise fatigue effect of Phyllanthus emblica L.: novel evidence from tannin conversion in vitro, metabolomics, and gut microbiota community analysis
Polyphenols are the main component of Phyllanthus emblica (PE). However, polyphenols are so easy to transform that it is unknown that how drying methods driven by heating affect the anti-fatigue effect of PE. Thi... (Source: Chinese Medicine)
Source: Chinese Medicine - October 1, 2023 Category: Complementary Medicine Authors: Dingkun Zhang, Xuan Deng, Mengqi Li, Min Qiu, Yifan Zhang, Gefei Li, Yurou Jiang, Peng Tan, Sanhu Fan, Youde Zheng, Junzhi Lin, Li Han and Haozhou Huang Tags: Research Source Type: research
Quality evaluation methods of chinese medicine based on scientific supervision: recent research progress and prospects
Traditional Chinese medicine (TCM) is increasingly getting attention worldwide, as it has played a very satisfactory role in treating COVID-19 during these past 3 years, and the Chinese government highly suppo... (Source: Chinese Medicine)
Source: Chinese Medicine - September 30, 2023 Category: Complementary Medicine Authors: Zhangmei Chen, Chi Teng Vong, Tiejun Zhang, Chun Yao, Yitao Wang and Hua Luo Tags: Review Source Type: research
Ginsenosides: changing the basic hallmarks of cancer cells to achieve the purpose of treating breast cancer
In 2021, breast cancer accounted for a substantial proportion of cancer cases and represented the second leading cause of cancer deaths among women worldwide. Although tumor cells originate from normal cells i... (Source: Chinese Medicine)
Source: Chinese Medicine - September 25, 2023 Category: Complementary Medicine Authors: Rui-yuan Jiang, Zi-ru Fang, Huan-ping Zhang, Jun-yao Xu, Jia-yu Zhu, Ke-yu Chen, Wei Wang, Xiao Jiang and Xiao-jia Wang Tags: Review Source Type: research
Exploring the potential use of Chinese herbs in regulating the inflammatory microenvironment of tumours based on the concept of ‘state-target identification and treatment’: a scooping review
Tumours do not exist in isolation from the organism; their growth, proliferation, motility, and immunosuppressive response are intricately connected to the tumour ’s microenvironment. As tumour cells and the mi... (Source: Chinese Medicine)
Source: Chinese Medicine - September 23, 2023 Category: Complementary Medicine Authors: Jing Lian, Dongxin Lin, Yuchan Huang, Xiaohui Chen, Lian Chen, Fan Zhang, Peiling Tang, Jinling Xie, Xiaotao Hou, Zhengcai Du, Jiagang Deng, Erwei Hao and Junhui Liu Tags: Review Source Type: research
Curdione induces ferroptosis mediated by m6A methylation via METTL14 and YTHDF2 in colorectal cancer
Curdione is a sesquiterpene isolated from Curcumae Rhizoma that possesses high biological activity and extensive pharmacological effects. As a traditional Chinese medicine, Curcumae Rhizoma can inhibit the develo... (Source: Chinese Medicine)
Source: Chinese Medicine - September 21, 2023 Category: Complementary Medicine Authors: Fang Wang, Zheng Sun, Qunyao Zhang, Hao Yang, Gang Yang, Qi Yang, Yimiao Zhu, Wenya Wu, Wenwen Xu and Xiaoyu Wu Tags: Research Source Type: research
Z-ligustilide preferentially caused mitochondrial dysfunction in AML HL-60 cells by activating nuclear receptors NUR77 and NOR1
Nuclear receptors NUR77 and NOR1 were identified as critical targets in acute myeloid leukemia (AML) therapy. Previously, we showed that Z-ligustilide (Z-LIG) selectively targeted AML by restoring NUR77 and NO... (Source: Chinese Medicine)
Source: Chinese Medicine - September 21, 2023 Category: Complementary Medicine Authors: Gen Liu, Zhi-gang Chen, Li-rong Yang, Yu-xia Rong, Qin Wang, Li Li, Qian-wei Lu, Ming-dong Jiang and Hong-yi Qi Tags: Research Source Type: research
