Expanding potential targets of herbal chemicals by node2vec based on herb –drug interactions
The identification of chemical –target interaction is key to pharmaceutical research and development, but the unclear materials basis and complex mechanisms of traditional medicine (TM) make it difficult, espec... (Source: Chinese Medicine)
Source: Chinese Medicine - June 1, 2023 Category: Complementary Medicine Authors: Dai-yan Zhang, Wen-qing Cui, Ling Hou, Jing Yang, Li-yang Lyu, Ze-yu Wang, Ke-Gang Linghu, Wen-bin He, Hua Yu and Yuan-jia Hu Tags: Research Source Type: research
UPLC-QTOF-MS with a chemical profiling approach for holistic quality evaluation between a material reference of Wen Dan decoction and its commercial preparations
Wen Dan decoction (WDD) has been a famous classic formula for resolving phlegm since ancient times in China. Currently, there are many types of WDD commercial preparations produced through modern technology. H... (Source: Chinese Medicine)
Source: Chinese Medicine - May 30, 2023 Category: Complementary Medicine Authors: Siyu Yang, Gan Chen, Man Yuan, Yan Zou, Hongmei Zhang and Hongxi Xu Tags: Research Source Type: research
Citrus alkaline extracts improve LPS-induced pulmonary fibrosis via epithelial mesenchymal transition signals
Acute respiratory distress syndrome (ARDS) is a serious life threatening clinical critical illness. ARDS-related pulmonary fibrosis is a common complication of ARDS. The occurrence of early pulmonary fibrosis ... (Source: Chinese Medicine)
Source: Chinese Medicine - May 29, 2023 Category: Complementary Medicine Authors: Li Junjie, Gu Cheng, Luo Kangkang, Li Yu, Yuan Zhiyao, Wu Xudong, Zhou Xianmei and Lu Xiaomin Tags: Research Source Type: research
Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer
Pancreatic cancer (PAC), a malignancy that is fatal and commonly diagnosed at a late stage. Despite considerable advancements in cancer treatment, the survival rate of PAC remains largely consistent for the pa... (Source: Chinese Medicine)
Source: Chinese Medicine - May 28, 2023 Category: Complementary Medicine Authors: Rong Wu, Zhichao Xi, Mengfan Liu, Hangui Ren, Rongchen Dai, Xue Jiang, Wan Najbah Nik Nabil, Yalin Wang, Jiling Feng, Qiong Chai, Qihan Dong and Hongxi Xu Tags: Research Source Type: research
TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea
Pulmonary fibrosis (PF) is a chronic and potentially fatal lung disease and disorder. Although the active ingredients of ginseng honeysuckle superfine powdered tea (GHSPT) have been proven to have anti-inflamm... (Source: Chinese Medicine)
Source: Chinese Medicine - May 24, 2023 Category: Complementary Medicine Authors: Xiaoli Li, Xin Yu, Yuan Gao, Wenqian Zhao, Yajuan Wang, Fei Yu, Chunli Fu, Haiqing Gao, Mei Cheng and Baoying Li Tags: Research Source Type: research
Traditional Chinese medicine in the era of immune checkpoint inhibitor: theory, development, and future directions
Immune checkpoint inhibitors (ICIs) have revolutionized cancer management and have been widely applied; however, they still have some limitations in terms of efficacy and toxicity. There are multiple treatment... (Source: Chinese Medicine)
Source: Chinese Medicine - May 20, 2023 Category: Complementary Medicine Authors: Yi-xuan Yu, Shuo Wang, Zhe-ning Liu, Xu Zhang, Zi-xin Hu, Hui-jing Dong, Xing-yu Lu, Jia-bin Zheng and Hui-juan Cui Tags: Review Source Type: research
Systematic analysis of randomised controlled trials of Chinese herb medicine for non-alcoholic steatohepatitis (NASH): implications for future drug development and trial design
Non-alcoholic steatohepatitis (NASH) is a liver disease currently lacking an approved therapy, resulting in significant clinical demand. Traditional Chinese medicines (TCMs) have been commonly used to manage N... (Source: Chinese Medicine)
Source: Chinese Medicine - May 19, 2023 Category: Complementary Medicine Authors: Xianwen Chen, Junnan Shi, Yunfeng Lai, Yan Xue, Carolina Oi Lam Ung and Hao Hu Tags: Review Source Type: research
Therapeutic mechanisms of the medicine and food homology formula Xiao-Ke-Yin on glucolipid metabolic dysfunction revealed by transcriptomics, metabolomics and microbiomics in mice
In recent decades, the prevalence of metabolic diseases, particularly diabetes, hyperlipidemia, obesity, and non-alcoholic fatty liver disease (NAFLD), has increased dramatically, causing great public health a... (Source: Chinese Medicine)
Source: Chinese Medicine - May 18, 2023 Category: Complementary Medicine Authors: Mei Li, Ding Cheng, Chuan Peng, Yujiao Huang, Jie Geng, Guangrui Huang, Ting Wang and Anlong Xu Tags: Research Source Type: research
Identification of the Main Chemical constituents and mechanism of Renshen Guben oral liquid against Renal Fibrosis
Renal fibrosis is the late stage of many chronic kidney diseases (CKD). Clinically, there is almost no effective treatment for renal fibrosis except dialysis. Renshen Guben oral liquid (RSGB) is a Chinese pate... (Source: Chinese Medicine)
Source: Chinese Medicine - May 17, 2023 Category: Complementary Medicine Authors: Junhong Zhang, Juqin Peng, Tong Zhang, Hong Jiang, Yuewen Qin, Hong Chen, Xiaofang Deng, Junguo Ren, Ping Wang and Haiyu Xu Tags: Research Source Type: research
Tanshinone IIA inhibits osteoclastogenesis in rheumatoid arthritis via LDHC-regulated ROS generation
Rheumatoid arthritis (RA) is characterized by bone destruction in the afflicted joints, and during the process of bone destruction, osteoclasts play a crucial role. Tanshinone IIA (Tan IIA) has shown anti-infl... (Source: Chinese Medicine)
Source: Chinese Medicine - May 15, 2023 Category: Complementary Medicine Authors: Qiuwei Peng, Jian Wang, Man Han, Minghong Zhao, Kesong Li, Tianming Lu, Qiuyan Guo and Quan Jiang Tags: Research Source Type: research
Correction: Shengjiang San alleviated sepsis-induced lung injury through its bidirectional regulatory effect
(Source: Chinese Medicine)
Source: Chinese Medicine - May 15, 2023 Category: Complementary Medicine Authors: Shifan Yan, Yu Jiang, Ting Yu, Changmiao Hou, Wen Xiao, Jing Xu, Huili Wen, Jingjing Wang, Shutong Li, Fang Chen, Shentang Li, Xiehong Liu, Hao Tan, Lianhong Zou, Yanjuan Liu and Yimin Zhu Tags: Correction Source Type: research
Exploring the effect of Yinzhihuang granules on alcoholic liver disease based on pharmacodynamics, network pharmacology and molecular docking
Yinzhihuang granules (YZHG) is a commonly used Chinese patent medicine for the treatment of liver disease. However, the mechanism of YZHG in alcoholic liver disease (ALD) is still unclear. (Source: Chinese Medicine)
Source: Chinese Medicine - May 11, 2023 Category: Complementary Medicine Authors: Yingying Tan, Fanqin Zhang, Xiaotian Fan, Shan Lu, Yingying Liu, Zhishan Wu, Zhihong Huang, Chao Wu, Guoliang Cheng, Bing Li, Jiaqi Huang, Antony Stalin, Wei Zhou and Jiarui Wu Tags: Research Source Type: research
Bushen-Yizhi formula ameliorates mitochondrial dysfunction and oxidative stress via AMPK/Sirt1 signaling pathway in D-gal-induced aging rats
As a major risk factor for neurodegenerative diseases, aging has become a heavy health care burden worldwide. Age-related decline in mitochondrial function and oxidative stress is strongly associated with neur... (Source: Chinese Medicine)
Source: Chinese Medicine - May 11, 2023 Category: Complementary Medicine Authors: Yanfang Liao, Yiyi Lai, Huilin Xu, Li Gao, Xiaomei Fu, Xue Wang, Qi Wang, Jiangang Shen, Jiansong Fang and Shuhuan Fang Tags: Research Source Type: research
Cyp4a12-mediated retinol metabolism in stellate cells is the antihepatic fibrosis mechanism of the Chinese medicine Fuzheng Huayu recipe
Hepatic stellate cells (HSCs), which contain multiple retinol-containing lipid droplets, are important profibrotic cells in liver fibrosis. Under Cyp4a12a/b oxidation, HSC activation was accompanied by the dow... (Source: Chinese Medicine)
Source: Chinese Medicine - May 9, 2023 Category: Complementary Medicine Authors: Da-bing Ping, Xin Sun, Yuan Peng and Cheng-hai Liu Tags: Research Source Type: research
Panax notoginseng saponins inhibits NLRP3 inflammasome-mediated pyroptosis by downregulating lncRNA-ANRIL in cardiorenal syndrome type 4
Cardiorenal syndrome type 4 (CRS4) is a complication of chronic kidney disease. Panax notoginseng saponins (PNS) have been confirmed to be efficient in cardiovascular diseases. Our study aimed to explore the ther... (Source: Chinese Medicine)
Source: Chinese Medicine - May 8, 2023 Category: Complementary Medicine Authors: Ying Xu, Luxi Cao, Wenli Zou, Rizhen Yu and Wei Shen Tags: Research Source Type: research
