Lipidomic analysis identified potential predictive biomarkers of statin response in subjects with Familial hypercholesterolemia
In conclusion, statins extensively modulate the overall serum lipid composition of FH individuals and these findings suggest that phosphatidyl-inositol molecules are potential predictive biomarkers of statin response.PMID:37827478 | DOI:10.1016/j.chemphyslip.2023.105348 (Source: Chemistry and Physics of Lipids)
Source: Chemistry and Physics of Lipids - October 12, 2023 Category: Lipidology Authors: Alvaro Cerda Raul Hernandes Bortolin Marcos Yukio Yoshinaga Renata Caroline Costa de Freitas Carolina Dagli-Hernandez Jessica Bassani Borges Victor Fernandes de Oliveira Rodrigo Marques Gon çalves Andre Arpad Faludi Gisele Medeiros Bastos Rosario Domingu Source Type: research

Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming
Chem Phys Lipids. 2023 Sep 23;257:105339. doi: 10.1016/j.chemphyslip.2023.105339. Online ahead of print.ABSTRACTThis paper presents an approach to study biochemical changes in human normal bronchial cells (BEpiC) and human cancer lung cells (A549) by Raman spectroscopy and Raman imaging combined with chemometric methods. Based on Raman spectra and Raman imaging combined with chemometric methods we have proved that peaks at 845 cm-1, 2845 cm-1, 2936 cm-1, 1444 cm-1, 750 cm-1, 1126 cm-1, 1584 cm-1, can be treated as Raman biomarkers probing phosphorylation, lipid reprogramming, oxidative phosphorylation and changes in choles...
Source: Chemistry and Physics of Lipids - September 25, 2023 Category: Lipidology Authors: Monika Kopec Karolina Beton-Mysur Halina Abramczyk Source Type: research

Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming
Chem Phys Lipids. 2023 Sep 23;257:105339. doi: 10.1016/j.chemphyslip.2023.105339. Online ahead of print.ABSTRACTThis paper presents an approach to study biochemical changes in human normal bronchial cells (BEpiC) and human cancer lung cells (A549) by Raman spectroscopy and Raman imaging combined with chemometric methods. Based on Raman spectra and Raman imaging combined with chemometric methods we have proved that peaks at 845 cm-1, 2845 cm-1, 2936 cm-1, 1444 cm-1, 750 cm-1, 1126 cm-1, 1584 cm-1, can be treated as Raman biomarkers probing phosphorylation, lipid reprogramming, oxidative phosphorylation and changes in choles...
Source: Chemistry and Physics of Lipids - September 25, 2023 Category: Lipidology Authors: Monika Kopec Karolina Beton-Mysur Halina Abramczyk Source Type: research

Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming
Chem Phys Lipids. 2023 Sep 23;257:105339. doi: 10.1016/j.chemphyslip.2023.105339. Online ahead of print.ABSTRACTThis paper presents an approach to study biochemical changes in human normal bronchial cells (BEpiC) and human cancer lung cells (A549) by Raman spectroscopy and Raman imaging combined with chemometric methods. Based on Raman spectra and Raman imaging combined with chemometric methods we have proved that peaks at 845 cm-1, 2845 cm-1, 2936 cm-1, 1444 cm-1, 750 cm-1, 1126 cm-1, 1584 cm-1, can be treated as Raman biomarkers probing phosphorylation, lipid reprogramming, oxidative phosphorylation and changes in choles...
Source: Chemistry and Physics of Lipids - September 25, 2023 Category: Lipidology Authors: Monika Kopec Karolina Beton-Mysur Halina Abramczyk Source Type: research

Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming
Chem Phys Lipids. 2023 Sep 23;257:105339. doi: 10.1016/j.chemphyslip.2023.105339. Online ahead of print.ABSTRACTThis paper presents an approach to study biochemical changes in human normal bronchial cells (BEpiC) and human cancer lung cells (A549) by Raman spectroscopy and Raman imaging combined with chemometric methods. Based on Raman spectra and Raman imaging combined with chemometric methods we have proved that peaks at 845 cm-1, 2845 cm-1, 2936 cm-1, 1444 cm-1, 750 cm-1, 1126 cm-1, 1584 cm-1, can be treated as Raman biomarkers probing phosphorylation, lipid reprogramming, oxidative phosphorylation and changes in choles...
Source: Chemistry and Physics of Lipids - September 25, 2023 Category: Lipidology Authors: Monika Kopec Karolina Beton-Mysur Halina Abramczyk Source Type: research

Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming
Chem Phys Lipids. 2023 Sep 23;257:105339. doi: 10.1016/j.chemphyslip.2023.105339. Online ahead of print.ABSTRACTThis paper presents an approach to study biochemical changes in human normal bronchial cells (BEpiC) and human cancer lung cells (A549) by Raman spectroscopy and Raman imaging combined with chemometric methods. Based on Raman spectra and Raman imaging combined with chemometric methods we have proved that peaks at 845 cm-1, 2845 cm-1, 2936 cm-1, 1444 cm-1, 750 cm-1, 1126 cm-1, 1584 cm-1, can be treated as Raman biomarkers probing phosphorylation, lipid reprogramming, oxidative phosphorylation and changes in choles...
Source: Chemistry and Physics of Lipids - September 25, 2023 Category: Lipidology Authors: Monika Kopec Karolina Beton-Mysur Halina Abramczyk Source Type: research

Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming
Chem Phys Lipids. 2023 Sep 23;257:105339. doi: 10.1016/j.chemphyslip.2023.105339. Online ahead of print.ABSTRACTThis paper presents an approach to study biochemical changes in human normal bronchial cells (BEpiC) and human cancer lung cells (A549) by Raman spectroscopy and Raman imaging combined with chemometric methods. Based on Raman spectra and Raman imaging combined with chemometric methods we have proved that peaks at 845 cm-1, 2845 cm-1, 2936 cm-1, 1444 cm-1, 750 cm-1, 1126 cm-1, 1584 cm-1, can be treated as Raman biomarkers probing phosphorylation, lipid reprogramming, oxidative phosphorylation and changes in choles...
Source: Chemistry and Physics of Lipids - September 25, 2023 Category: Lipidology Authors: Monika Kopec Karolina Beton-Mysur Halina Abramczyk Source Type: research

Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming
Chem Phys Lipids. 2023 Sep 23;257:105339. doi: 10.1016/j.chemphyslip.2023.105339. Online ahead of print.ABSTRACTThis paper presents an approach to study biochemical changes in human normal bronchial cells (BEpiC) and human cancer lung cells (A549) by Raman spectroscopy and Raman imaging combined with chemometric methods. Based on Raman spectra and Raman imaging combined with chemometric methods we have proved that peaks at 845 cm-1, 2845 cm-1, 2936 cm-1, 1444 cm-1, 750 cm-1, 1126 cm-1, 1584 cm-1, can be treated as Raman biomarkers probing phosphorylation, lipid reprogramming, oxidative phosphorylation and changes in choles...
Source: Chemistry and Physics of Lipids - September 25, 2023 Category: Lipidology Authors: Monika Kopec Karolina Beton-Mysur Halina Abramczyk Source Type: research

Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming
Chem Phys Lipids. 2023 Sep 23;257:105339. doi: 10.1016/j.chemphyslip.2023.105339. Online ahead of print.ABSTRACTThis paper presents an approach to study biochemical changes in human normal bronchial cells (BEpiC) and human cancer lung cells (A549) by Raman spectroscopy and Raman imaging combined with chemometric methods. Based on Raman spectra and Raman imaging combined with chemometric methods we have proved that peaks at 845 cm-1, 2845 cm-1, 2936 cm-1, 1444 cm-1, 750 cm-1, 1126 cm-1, 1584 cm-1, can be treated as Raman biomarkers probing phosphorylation, lipid reprogramming, oxidative phosphorylation and changes in choles...
Source: Chemistry and Physics of Lipids - September 25, 2023 Category: Lipidology Authors: Monika Kopec Karolina Beton-Mysur Halina Abramczyk Source Type: research

Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming
Chem Phys Lipids. 2023 Sep 23;257:105339. doi: 10.1016/j.chemphyslip.2023.105339. Online ahead of print.ABSTRACTThis paper presents an approach to study biochemical changes in human normal bronchial cells (BEpiC) and human cancer lung cells (A549) by Raman spectroscopy and Raman imaging combined with chemometric methods. Based on Raman spectra and Raman imaging combined with chemometric methods we have proved that peaks at 845 cm-1, 2845 cm-1, 2936 cm-1, 1444 cm-1, 750 cm-1, 1126 cm-1, 1584 cm-1, can be treated as Raman biomarkers probing phosphorylation, lipid reprogramming, oxidative phosphorylation and changes in choles...
Source: Chemistry and Physics of Lipids - September 25, 2023 Category: Lipidology Authors: Monika Kopec Karolina Beton-Mysur Halina Abramczyk Source Type: research

Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming
Chem Phys Lipids. 2023 Sep 23;257:105339. doi: 10.1016/j.chemphyslip.2023.105339. Online ahead of print.ABSTRACTThis paper presents an approach to study biochemical changes in human normal bronchial cells (BEpiC) and human cancer lung cells (A549) by Raman spectroscopy and Raman imaging combined with chemometric methods. Based on Raman spectra and Raman imaging combined with chemometric methods we have proved that peaks at 845 cm-1, 2845 cm-1, 2936 cm-1, 1444 cm-1, 750 cm-1, 1126 cm-1, 1584 cm-1, can be treated as Raman biomarkers probing phosphorylation, lipid reprogramming, oxidative phosphorylation and changes in choles...
Source: Chemistry and Physics of Lipids - September 25, 2023 Category: Lipidology Authors: Monika Kopec Karolina Beton-Mysur Halina Abramczyk Source Type: research

Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming
Chem Phys Lipids. 2023 Sep 23;257:105339. doi: 10.1016/j.chemphyslip.2023.105339. Online ahead of print.ABSTRACTThis paper presents an approach to study biochemical changes in human normal bronchial cells (BEpiC) and human cancer lung cells (A549) by Raman spectroscopy and Raman imaging combined with chemometric methods. Based on Raman spectra and Raman imaging combined with chemometric methods we have proved that peaks at 845 cm-1, 2845 cm-1, 2936 cm-1, 1444 cm-1, 750 cm-1, 1126 cm-1, 1584 cm-1, can be treated as Raman biomarkers probing phosphorylation, lipid reprogramming, oxidative phosphorylation and changes in choles...
Source: Chemistry and Physics of Lipids - September 25, 2023 Category: Lipidology Authors: Monika Kopec Karolina Beton-Mysur Halina Abramczyk Source Type: research

Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming
Chem Phys Lipids. 2023 Sep 23:105339. doi: 10.1016/j.chemphyslip.2023.105339. Online ahead of print.ABSTRACTThis paper presents an approach to study biochemical changes in human normal bronchial cells (BEpiC) and human cancer lung cells (A549) by Raman spectroscopy and Raman imaging combined with chemometric methods. Based on Raman spectra and Raman imaging combined with chemometric methods we have proved that peaks at 845cm-1, 2845cm-1, 2936cm-1, 1444cm-1, 750cm-1, 1126cm-1, 1584cm-1, can be treated as Raman biomarkers probing phosphorylation, lipid reprogramming, oxidative phosphorylation and changes in cholesterol and c...
Source: Chemistry and Physics of Lipids - September 25, 2023 Category: Lipidology Authors: Monika Kopec Karolina Beton-Mysur Halina Abramczyk Source Type: research

Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming
Chem Phys Lipids. 2023 Sep 23:105339. doi: 10.1016/j.chemphyslip.2023.105339. Online ahead of print.ABSTRACTThis paper presents an approach to study biochemical changes in human normal bronchial cells (BEpiC) and human cancer lung cells (A549) by Raman spectroscopy and Raman imaging combined with chemometric methods. Based on Raman spectra and Raman imaging combined with chemometric methods we have proved that peaks at 845cm-1, 2845cm-1, 2936cm-1, 1444cm-1, 750cm-1, 1126cm-1, 1584cm-1, can be treated as Raman biomarkers probing phosphorylation, lipid reprogramming, oxidative phosphorylation and changes in cholesterol and c...
Source: Chemistry and Physics of Lipids - September 25, 2023 Category: Lipidology Authors: Monika Kopec Karolina Beton-Mysur Halina Abramczyk Source Type: research

The influence of Leucidal - eco-preservative from radish - on model lipid membranes and selected pathogenic bacteria
Chem Phys Lipids. 2023 Sep 14;256:105338. doi: 10.1016/j.chemphyslip.2023.105338. Online ahead of print.ABSTRACTIn this work the effect of Leucidal - a natural preservative from radish dedicated to be used in cosmetics - on bacteria cells and model bacteria membranes was investigated. To get insight into the mechanism of action of this formulation the lipid Langmuir monolayers imitating Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) membranes were prepared. Then, the influence of Leucidal on model systems was investigated by means of the surface pressure/area measurements, penetration studies and Brewster...
Source: Chemistry and Physics of Lipids - September 16, 2023 Category: Lipidology Authors: Beata Wy żga Magdalena Sk óra Katarzyna H ąc-Wydro Source Type: research