Structural insights into the TRPV4-RhoA complex offer clues to solve the puzzle of TRPV4 channelopathies
Cell Calcium. 2023 Oct 4;116:102814. doi: 10.1016/j.ceca.2023.102814. Online ahead of print.NO ABSTRACTPMID:37839180 | DOI:10.1016/j.ceca.2023.102814 (Source: Cell Calcium)
Source: Cell Calcium - October 15, 2023 Category: Cytology Authors: Xueming Hu Hongzhen Hu Source Type: research

Structural insights into the TRPV4-RhoA complex offer clues to solve the puzzle of TRPV4 channelopathies
Cell Calcium. 2023 Oct 4;116:102814. doi: 10.1016/j.ceca.2023.102814. Online ahead of print.NO ABSTRACTPMID:37839180 | DOI:10.1016/j.ceca.2023.102814 (Source: Cell Calcium)
Source: Cell Calcium - October 15, 2023 Category: Cytology Authors: Xueming Hu Hongzhen Hu Source Type: research

Commentary: Untangling the structural and enzymatic roles of CaMKII at the synapse
Cell Calcium. 2023 Oct 5;116:102813. doi: 10.1016/j.ceca.2023.102813. Online ahead of print.NO ABSTRACTPMID:37806033 | DOI:10.1016/j.ceca.2023.102813 (Source: Cell Calcium)
Source: Cell Calcium - October 8, 2023 Category: Cytology Authors: Daniela Anderson A J Robison Source Type: research

Commentary: Untangling the structural and enzymatic roles of CaMKII at the synapse
Cell Calcium. 2023 Oct 5;116:102813. doi: 10.1016/j.ceca.2023.102813. Online ahead of print.NO ABSTRACTPMID:37806033 | DOI:10.1016/j.ceca.2023.102813 (Source: Cell Calcium)
Source: Cell Calcium - October 8, 2023 Category: Cytology Authors: Daniela Anderson A J Robison Source Type: research

Commentary: Untangling the structural and enzymatic roles of CaMKII at the synapse
Cell Calcium. 2023 Oct 5;116:102813. doi: 10.1016/j.ceca.2023.102813. Online ahead of print.NO ABSTRACTPMID:37806033 | DOI:10.1016/j.ceca.2023.102813 (Source: Cell Calcium)
Source: Cell Calcium - October 8, 2023 Category: Cytology Authors: Daniela Anderson A J Robison Source Type: research

Commentary: Untangling the structural and enzymatic roles of CaMKII at the synapse
Cell Calcium. 2023 Oct 5;116:102813. doi: 10.1016/j.ceca.2023.102813. Online ahead of print.NO ABSTRACTPMID:37806033 | DOI:10.1016/j.ceca.2023.102813 (Source: Cell Calcium)
Source: Cell Calcium - October 8, 2023 Category: Cytology Authors: Daniela Anderson A J Robison Source Type: research

Commentary: Untangling the structural and enzymatic roles of CaMKII at the synapse
Cell Calcium. 2023 Oct 5;116:102813. doi: 10.1016/j.ceca.2023.102813. Online ahead of print.NO ABSTRACTPMID:37806033 | DOI:10.1016/j.ceca.2023.102813 (Source: Cell Calcium)
Source: Cell Calcium - October 8, 2023 Category: Cytology Authors: Daniela Anderson A J Robison Source Type: research

Commentary: Untangling the structural and enzymatic roles of CaMKII at the synapse
Cell Calcium. 2023 Oct 5;116:102813. doi: 10.1016/j.ceca.2023.102813. Online ahead of print.NO ABSTRACTPMID:37806033 | DOI:10.1016/j.ceca.2023.102813 (Source: Cell Calcium)
Source: Cell Calcium - October 8, 2023 Category: Cytology Authors: Daniela Anderson A J Robison Source Type: research

Pentameric TRPV3: An artifact or a clue to channel function?
Cell Calcium. 2023 Sep 29;116:102812. doi: 10.1016/j.ceca.2023.102812. Online ahead of print.NO ABSTRACTPMID:37804687 | DOI:10.1016/j.ceca.2023.102812 (Source: Cell Calcium)
Source: Cell Calcium - October 7, 2023 Category: Cytology Authors: Arthur Neuberger Alexander I Sobolevsky Source Type: research

Pan-cancer analysis reveals the prognostic gene CASR suppresses tumor progression and epithelial-mesenchymal transition in renal clear cell carcinoma
Cell Calcium. 2023 Sep 22;116:102803. doi: 10.1016/j.ceca.2023.102803. Online ahead of print.ABSTRACTCalcium-sensing receptor (CASR), primarily found in the parathyroid gland and other tissues, plays a crucial role in sensing and regulating extracellular calcium, which was also aberrantly expressed in human tumors. Nevertheless, a comprehensive analysis of CASR in pan-cancer has yet to be conducted. To gain a better understanding of CASR in pan-cancer, data profiles on CASR cancers were collected from TCGA database. The expression level, clinical significance, prognostic value, and potential mechanisms of CASR in pan-cance...
Source: Cell Calcium - October 7, 2023 Category: Cytology Authors: Zijian Zhou Dexiang Feng Yuanyuan Yang Peng Gao Lujia Wang Zhong Wu Source Type: research

Pentameric TRPV3: An artifact or a clue to channel function?
Cell Calcium. 2023 Sep 29;116:102812. doi: 10.1016/j.ceca.2023.102812. Online ahead of print.NO ABSTRACTPMID:37804687 | DOI:10.1016/j.ceca.2023.102812 (Source: Cell Calcium)
Source: Cell Calcium - October 7, 2023 Category: Cytology Authors: Arthur Neuberger Alexander I Sobolevsky Source Type: research

Pan-cancer analysis reveals the prognostic gene CASR suppresses tumor progression and epithelial-mesenchymal transition in renal clear cell carcinoma
Cell Calcium. 2023 Sep 22;116:102803. doi: 10.1016/j.ceca.2023.102803. Online ahead of print.ABSTRACTCalcium-sensing receptor (CASR), primarily found in the parathyroid gland and other tissues, plays a crucial role in sensing and regulating extracellular calcium, which was also aberrantly expressed in human tumors. Nevertheless, a comprehensive analysis of CASR in pan-cancer has yet to be conducted. To gain a better understanding of CASR in pan-cancer, data profiles on CASR cancers were collected from TCGA database. The expression level, clinical significance, prognostic value, and potential mechanisms of CASR in pan-cance...
Source: Cell Calcium - October 7, 2023 Category: Cytology Authors: Zijian Zhou Dexiang Feng Yuanyuan Yang Peng Gao Lujia Wang Zhong Wu Source Type: research

Dual function of the choroid plexus: Cerebrospinal fluid production and control of brain ion homeostasis
Cell Calcium. 2023 Sep 15;116:102797. doi: 10.1016/j.ceca.2023.102797. Online ahead of print.ABSTRACTThe choroid plexus is a small monolayered epithelium located in the brain ventricles and serves to secrete the cerebrospinal fluid (CSF) that envelops the brain and fills the central ventricles. The CSF secretion is sustained with a concerted effort of a range of membrane transporters located in a polarized fashion in this tissue. Prominent amongst these are the Na+/K+-ATPase, the Na+,K+,2Cl- cotransporter (NKCC1), and several HCO3- transporters, which together support the net transepithelial transport of the major electrol...
Source: Cell Calcium - October 6, 2023 Category: Cytology Authors: Nanna MacAulay Trine L Toft-Bertelsen Source Type: research

The conducting state of TRPA1 modulates channel lateral mobility
Cell Calcium. 2023 Sep 18;116:102800. doi: 10.1016/j.ceca.2023.102800. Online ahead of print.ABSTRACTWe have studied Danio rerio (Zebrafish) TRPA1 channel using a method that combines single channel electrophysiological and optical recordings to evaluate lateral mobility and channel gating simultaneously in single channels. TRPA1 channel activation by two distinct chemical ligands: allyl isothiocyanate (AITC) and TRPswitch B, results in substantial reduction of channel lateral mobility at the plasma membrane. Incubation with the cholesterol sequestering agent methyl-β-cyclodextrin (MβCD), prevents the reduction on latera...
Source: Cell Calcium - September 30, 2023 Category: Cytology Authors: Alicia Sampieri Teresa Padilla-Flores Aditya R Thawani Pui-Ying Lam Matthew J Fuchter Randall Peterson Luis Vaca Source Type: research

The conducting state of TRPA1 modulates channel lateral mobility
Cell Calcium. 2023 Sep 18;116:102800. doi: 10.1016/j.ceca.2023.102800. Online ahead of print.ABSTRACTWe have studied Danio rerio (Zebrafish) TRPA1 channel using a method that combines single channel electrophysiological and optical recordings to evaluate lateral mobility and channel gating simultaneously in single channels. TRPA1 channel activation by two distinct chemical ligands: allyl isothiocyanate (AITC) and TRPswitch B, results in substantial reduction of channel lateral mobility at the plasma membrane. Incubation with the cholesterol sequestering agent methyl-β-cyclodextrin (MβCD), prevents the reduction on latera...
Source: Cell Calcium - September 30, 2023 Category: Cytology Authors: Alicia Sampieri Teresa Padilla-Flores Aditya R Thawani Pui-Ying Lam Matthew J Fuchter Randall Peterson Luis Vaca Source Type: research