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< em > In silico < /em > Evaluation of ACE2 Inhibition by < em > Prunus armeniaca < /em > L. and < em > in vivo < /em > Toxicity Study
CONCLUSION: Four compounds from Prunus armeniaca seem to exert an inhibitory potential of ACE2.PMID:38192214 | DOI:10.2174/011871529X265182231211103724 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - January 9, 2024 Category: Drugs & Pharmacology Authors: Ismail Bouadid Soumia Moujane Mourad Akdad Moualij Benaissa Mohamed Eddouks Source Type: research

Therapeutic Drug Monitoring of Voriconazole in Children with Hematologic Malignancy and Invasive Fungal Infections: An RCT from a Tertiary Care Centre in India
CONCLUSION: Only five out of 15 (33.3%) children had voriconazole serum levels within the therapeutic range. Alterations in dose had to be done in the remaining to achieve the recommended serum levels. Thus, we recommend TDM for all children of hematologic malignancy receiving voriconazole for better management. Our findings also revealed that children with AML had lower than recommended levels of voriconazole on TDM evaluation, whereas those with ALL had normal to elevated levels of voriconazole.PMID:38192215 | DOI:10.2174/011871529X245299231102055046 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - January 9, 2024 Category: Drugs & Pharmacology Authors: Neha Sharad Gagandeep Singh Immaculata Xess Reshu Agarwal Tulika Seth K H Reeta Sweta Kothari Source Type: research

< em > In silico < /em > Evaluation of ACE2 Inhibition by < em > Prunus armeniaca < /em > L. and < em > in vivo < /em > Toxicity Study
CONCLUSION: Four compounds from Prunus armeniaca seem to exert an inhibitory potential of ACE2.PMID:38192214 | DOI:10.2174/011871529X265182231211103724 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - January 9, 2024 Category: Drugs & Pharmacology Authors: Ismail Bouadid Soumia Moujane Mourad Akdad Moualij Benaissa Mohamed Eddouks Source Type: research

Therapeutic Drug Monitoring of Voriconazole in Children with Hematologic Malignancy and Invasive Fungal Infections: An RCT from a Tertiary Care Centre in India
CONCLUSION: Only five out of 15 (33.3%) children had voriconazole serum levels within the therapeutic range. Alterations in dose had to be done in the remaining to achieve the recommended serum levels. Thus, we recommend TDM for all children of hematologic malignancy receiving voriconazole for better management. Our findings also revealed that children with AML had lower than recommended levels of voriconazole on TDM evaluation, whereas those with ALL had normal to elevated levels of voriconazole.PMID:38192215 | DOI:10.2174/011871529X245299231102055046 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - January 9, 2024 Category: Drugs & Pharmacology Authors: Neha Sharad Gagandeep Singh Immaculata Xess Reshu Agarwal Tulika Seth K H Reeta Sweta Kothari Source Type: research

< em > In silico < /em > Evaluation of ACE2 Inhibition by < em > Prunus armeniaca < /em > L. and < em > in vivo < /em > Toxicity Study
CONCLUSION: Four compounds from Prunus armeniaca seem to exert an inhibitory potential of ACE2.PMID:38192214 | DOI:10.2174/011871529X265182231211103724 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - January 9, 2024 Category: Drugs & Pharmacology Authors: Ismail Bouadid Soumia Moujane Mourad Akdad Moualij Benaissa Mohamed Eddouks Source Type: research

Therapeutic Drug Monitoring of Voriconazole in Children with Hematologic Malignancy and Invasive Fungal Infections: An RCT from a Tertiary Care Centre in India
CONCLUSION: Only five out of 15 (33.3%) children had voriconazole serum levels within the therapeutic range. Alterations in dose had to be done in the remaining to achieve the recommended serum levels. Thus, we recommend TDM for all children of hematologic malignancy receiving voriconazole for better management. Our findings also revealed that children with AML had lower than recommended levels of voriconazole on TDM evaluation, whereas those with ALL had normal to elevated levels of voriconazole.PMID:38192215 | DOI:10.2174/011871529X245299231102055046 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - January 9, 2024 Category: Drugs & Pharmacology Authors: Neha Sharad Gagandeep Singh Immaculata Xess Reshu Agarwal Tulika Seth K H Reeta Sweta Kothari Source Type: research

< em > In silico < /em > Evaluation of ACE2 Inhibition by < em > Prunus armeniaca < /em > L. and < em > in vivo < /em > Toxicity Study
CONCLUSION: Four compounds from Prunus armeniaca seem to exert an inhibitory potential of ACE2.PMID:38192214 | DOI:10.2174/011871529X265182231211103724 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - January 9, 2024 Category: Drugs & Pharmacology Authors: Ismail Bouadid Soumia Moujane Mourad Akdad Moualij Benaissa Mohamed Eddouks Source Type: research

Therapeutic Drug Monitoring of Voriconazole in Children with Hematologic Malignancy and Invasive Fungal Infections: An RCT from a Tertiary Care Centre in India
CONCLUSION: Only five out of 15 (33.3%) children had voriconazole serum levels within the therapeutic range. Alterations in dose had to be done in the remaining to achieve the recommended serum levels. Thus, we recommend TDM for all children of hematologic malignancy receiving voriconazole for better management. Our findings also revealed that children with AML had lower than recommended levels of voriconazole on TDM evaluation, whereas those with ALL had normal to elevated levels of voriconazole.PMID:38192215 | DOI:10.2174/011871529X245299231102055046 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - January 9, 2024 Category: Drugs & Pharmacology Authors: Neha Sharad Gagandeep Singh Immaculata Xess Reshu Agarwal Tulika Seth K H Reeta Sweta Kothari Source Type: research

< em > In silico < /em > Evaluation of ACE2 Inhibition by < em > Prunus armeniaca < /em > L. and < em > in vivo < /em > Toxicity Study
CONCLUSION: Four compounds from Prunus armeniaca seem to exert an inhibitory potential of ACE2.PMID:38192214 | DOI:10.2174/011871529X265182231211103724 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - January 9, 2024 Category: Drugs & Pharmacology Authors: Ismail Bouadid Soumia Moujane Mourad Akdad Moualij Benaissa Mohamed Eddouks Source Type: research

Therapeutic Drug Monitoring of Voriconazole in Children with Hematologic Malignancy and Invasive Fungal Infections: An RCT from a Tertiary Care Centre in India
CONCLUSION: Only five out of 15 (33.3%) children had voriconazole serum levels within the therapeutic range. Alterations in dose had to be done in the remaining to achieve the recommended serum levels. Thus, we recommend TDM for all children of hematologic malignancy receiving voriconazole for better management. Our findings also revealed that children with AML had lower than recommended levels of voriconazole on TDM evaluation, whereas those with ALL had normal to elevated levels of voriconazole.PMID:38192215 | DOI:10.2174/011871529X245299231102055046 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - January 9, 2024 Category: Drugs & Pharmacology Authors: Neha Sharad Gagandeep Singh Immaculata Xess Reshu Agarwal Tulika Seth K H Reeta Sweta Kothari Source Type: research

< em > In silico < /em > Evaluation of ACE2 Inhibition by < em > Prunus armeniaca < /em > L. and < em > in vivo < /em > Toxicity Study
CONCLUSION: Four compounds from Prunus armeniaca seem to exert an inhibitory potential of ACE2.PMID:38192214 | DOI:10.2174/011871529X265182231211103724 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - January 9, 2024 Category: Drugs & Pharmacology Authors: Ismail Bouadid Soumia Moujane Mourad Akdad Moualij Benaissa Mohamed Eddouks Source Type: research

Therapeutic Drug Monitoring of Voriconazole in Children with Hematologic Malignancy and Invasive Fungal Infections: An RCT from a Tertiary Care Centre in India
CONCLUSION: Only five out of 15 (33.3%) children had voriconazole serum levels within the therapeutic range. Alterations in dose had to be done in the remaining to achieve the recommended serum levels. Thus, we recommend TDM for all children of hematologic malignancy receiving voriconazole for better management. Our findings also revealed that children with AML had lower than recommended levels of voriconazole on TDM evaluation, whereas those with ALL had normal to elevated levels of voriconazole.PMID:38192215 | DOI:10.2174/011871529X245299231102055046 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - January 9, 2024 Category: Drugs & Pharmacology Authors: Neha Sharad Gagandeep Singh Immaculata Xess Reshu Agarwal Tulika Seth K H Reeta Sweta Kothari Source Type: research

< em > In silico < /em > Evaluation of ACE2 Inhibition by < em > Prunus armeniaca < /em > L. and < em > in vivo < /em > Toxicity Study
CONCLUSION: Four compounds from Prunus armeniaca seem to exert an inhibitory potential of ACE2.PMID:38192214 | DOI:10.2174/011871529X265182231211103724 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - January 9, 2024 Category: Drugs & Pharmacology Authors: Ismail Bouadid Soumia Moujane Mourad Akdad Moualij Benaissa Mohamed Eddouks Source Type: research

Therapeutic Drug Monitoring of Voriconazole in Children with Hematologic Malignancy and Invasive Fungal Infections: An RCT from a Tertiary Care Centre in India
CONCLUSION: Only five out of 15 (33.3%) children had voriconazole serum levels within the therapeutic range. Alterations in dose had to be done in the remaining to achieve the recommended serum levels. Thus, we recommend TDM for all children of hematologic malignancy receiving voriconazole for better management. Our findings also revealed that children with AML had lower than recommended levels of voriconazole on TDM evaluation, whereas those with ALL had normal to elevated levels of voriconazole.PMID:38192215 | DOI:10.2174/011871529X245299231102055046 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - January 9, 2024 Category: Drugs & Pharmacology Authors: Neha Sharad Gagandeep Singh Immaculata Xess Reshu Agarwal Tulika Seth K H Reeta Sweta Kothari Source Type: research

< em > In silico < /em > Evaluation of ACE2 Inhibition by < em > Prunus armeniaca < /em > L. and < em > in vivo < /em > Toxicity Study
CONCLUSION: Four compounds from Prunus armeniaca seem to exert an inhibitory potential of ACE2.PMID:38192214 | DOI:10.2174/011871529X265182231211103724 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - January 9, 2024 Category: Drugs & Pharmacology Authors: Ismail Bouadid Soumia Moujane Mourad Akdad Moualij Benaissa Mohamed Eddouks Source Type: research