Assessing the Frequency of COVID-19 in Patients Undergoing Primary Percutaneous Coronary Intervention (PCI)
CONCLUSION: The high occurrence of COVID-19 among myocardial infarction (MI) patients undergoing primary percutaneous coronary intervention (PCI) is worth noting. Further investigation is recommended to explore the impact of demographic and contextual factors on the severity and outcomes of primary PCI in MI patients with COVID-19, as well as the underlying mechanisms involved.PMID:37946346 | DOI:10.2174/011871529X261360231103075012 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - November 10, 2023 Category: Drugs & Pharmacology Authors: Mahdi Zahedi Faezeh Davanloo Source Type: research

Amelioration of 5-Fluorouracil Induced Nephrotoxicity by Acacia catechu through Overcoming Oxidative Damage and Inflammation in Wistar Rats
CONCLUSION: The ethyl acetate fraction of A. catechu leaves exhibited a mitigating influence on the renal impairment caused by 5-FU, showcasing its potential as a nephroprotective agent capable of preventing and ameliorating 5-FU-induced nephrotoxicity.PMID:37946347 | DOI:10.2174/011871529X274030231102065433 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - November 10, 2023 Category: Drugs & Pharmacology Authors: Gayatri Jaising Gadekar Pranali Anandrao Bhandare Deepti Dinesh Bandawane Source Type: research

Assessing the Frequency of COVID-19 in Patients Undergoing Primary Percutaneous Coronary Intervention (PCI)
CONCLUSION: The high occurrence of COVID-19 among myocardial infarction (MI) patients undergoing primary percutaneous coronary intervention (PCI) is worth noting. Further investigation is recommended to explore the impact of demographic and contextual factors on the severity and outcomes of primary PCI in MI patients with COVID-19, as well as the underlying mechanisms involved.PMID:37946346 | DOI:10.2174/011871529X261360231103075012 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - November 10, 2023 Category: Drugs & Pharmacology Authors: Mahdi Zahedi Faezeh Davanloo Source Type: research

Amelioration of 5-Fluorouracil Induced Nephrotoxicity by Acacia catechu through Overcoming Oxidative Damage and Inflammation in Wistar Rats
CONCLUSION: The ethyl acetate fraction of A. catechu leaves exhibited a mitigating influence on the renal impairment caused by 5-FU, showcasing its potential as a nephroprotective agent capable of preventing and ameliorating 5-FU-induced nephrotoxicity.PMID:37946347 | DOI:10.2174/011871529X274030231102065433 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - November 10, 2023 Category: Drugs & Pharmacology Authors: Gayatri Jaising Gadekar Pranali Anandrao Bhandare Deepti Dinesh Bandawane Source Type: research

Assessing the Frequency of COVID-19 in Patients Undergoing Primary Percutaneous Coronary Intervention (PCI)
CONCLUSION: The high occurrence of COVID-19 among myocardial infarction (MI) patients undergoing primary percutaneous coronary intervention (PCI) is worth noting. Further investigation is recommended to explore the impact of demographic and contextual factors on the severity and outcomes of primary PCI in MI patients with COVID-19, as well as the underlying mechanisms involved.PMID:37946346 | DOI:10.2174/011871529X261360231103075012 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - November 10, 2023 Category: Drugs & Pharmacology Authors: Mahdi Zahedi Faezeh Davanloo Source Type: research

Amelioration of 5-Fluorouracil Induced Nephrotoxicity by Acacia catechu through Overcoming Oxidative Damage and Inflammation in Wistar Rats
CONCLUSION: The ethyl acetate fraction of A. catechu leaves exhibited a mitigating influence on the renal impairment caused by 5-FU, showcasing its potential as a nephroprotective agent capable of preventing and ameliorating 5-FU-induced nephrotoxicity.PMID:37946347 | DOI:10.2174/011871529X274030231102065433 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - November 10, 2023 Category: Drugs & Pharmacology Authors: Gayatri Jaising Gadekar Pranali Anandrao Bhandare Deepti Dinesh Bandawane Source Type: research

Updates in the Pharmacotherapy of Pulmonary Hypertension in Patients with Heart Failure with Preserved Ejection Fraction
Cardiovasc Hematol Disord Drug Targets. 2023 Oct 25. doi: 10.2174/011871529X258234230921112507. Online ahead of print.ABSTRACTPulmonary hypertension (PH) associated with left heart disease (LHD) is a complex cardiopulmonary condition where a variable degree of pulmonary congestion, arterial vasoconstriction and vascular remodeling can lead to PH and right heart strain. Right heart dysfunction has a significant prognostic impact on these patients. Therefore, preserving right ventricular (RV) function is an important treatment goal. However, the treatment of PH in patients with left heart disease has produced conflicting evi...
Source: Cardiovascular and Hematological Disorders Drug Targets - November 3, 2023 Category: Drugs & Pharmacology Authors: Fernando Segovia Hernando Garcia Haider Alkhateeb Debabrata Mukherjee Nils Nickel Source Type: research

Current Perspective and Mechanistic Insights on Bioactive Plant Secondary Metabolites for the Prevention and Treatment of Cardiovascular Diseases
Cardiovasc Hematol Disord Drug Targets. 2023 Oct 26. doi: 10.2174/011871529X262371231009132426. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs) are one of the most prevalent medical conditions of modern era and are one of the primary causes of adult mortality in both developing and developed countries. Conventional medications such as use of aspirin, beta-blockers, statins and angiotensin- converting enzyme inhibitors involve use of drugs with many antagonistic effects. Hence, alternative therapies which are safe, effective, and relatively cheap are increasingly being investigated for the treatment and prevent...
Source: Cardiovascular and Hematological Disorders Drug Targets - November 3, 2023 Category: Drugs & Pharmacology Authors: Jyotika Grewal Vijay Kumar Yashika Gandhi Hemant Rawat Ravindra Singh Arjun Singh Ch V Narasimhaji Rabinarayan Acharya Sujeet K Mishra Source Type: research

Assessment of the Heart's Left and Right Ventricles (EF and TAPSE) in CABG Surgery Patients before and after Cardiac Rehabilitation
CONCLUSION: Completion of a cardiac rehabilitation program leads to significant improvement in left ventricular function, while the improvement in right ventricular function is relatively modest. Moreover, a significant proportion of patients were able to resume their normal daily activities after completing the rehabilitation phase.PMID:37921164 | DOI:10.2174/011871529X250233231017043628 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - November 3, 2023 Category: Drugs & Pharmacology Authors: Mahdi Zahedi Fahime Safi Source Type: research

Decentralization and Virtualization of INR-based Anticoagulation Control During the COVID-19 Pandemic
CONCLUSION: Decentralization and virtualization of the INR clinic have similar TTR results if conducted properly.PMID:37921213 | DOI:10.2174/011871529X242935231026105854 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - November 3, 2023 Category: Drugs & Pharmacology Authors: Abdulrahman Almesned Abdullah Alqwaee Bayan Abusiryeh Ahmad Almeman Source Type: research

Updates in the Pharmacotherapy of Pulmonary Hypertension in Patients with Heart Failure with Preserved Ejection Fraction
Cardiovasc Hematol Disord Drug Targets. 2023 Oct 25. doi: 10.2174/011871529X258234230921112507. Online ahead of print.ABSTRACTPulmonary hypertension (PH) associated with left heart disease (LHD) is a complex cardiopulmonary condition where a variable degree of pulmonary congestion, arterial vasoconstriction and vascular remodeling can lead to PH and right heart strain. Right heart dysfunction has a significant prognostic impact on these patients. Therefore, preserving right ventricular (RV) function is an important treatment goal. However, the treatment of PH in patients with left heart disease has produced conflicting evi...
Source: Cardiovascular and Hematological Disorders Drug Targets - November 3, 2023 Category: Drugs & Pharmacology Authors: Fernando Segovia Hernando Garcia Haider Alkhateeb Debabrata Mukherjee Nils Nickel Source Type: research

Current Perspective and Mechanistic Insights on Bioactive Plant Secondary Metabolites for the Prevention and Treatment of Cardiovascular Diseases
Cardiovasc Hematol Disord Drug Targets. 2023 Oct 26. doi: 10.2174/011871529X262371231009132426. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs) are one of the most prevalent medical conditions of modern era and are one of the primary causes of adult mortality in both developing and developed countries. Conventional medications such as use of aspirin, beta-blockers, statins and angiotensin- converting enzyme inhibitors involve use of drugs with many antagonistic effects. Hence, alternative therapies which are safe, effective, and relatively cheap are increasingly being investigated for the treatment and prevent...
Source: Cardiovascular and Hematological Disorders Drug Targets - November 3, 2023 Category: Drugs & Pharmacology Authors: Jyotika Grewal Vijay Kumar Yashika Gandhi Hemant Rawat Ravindra Singh Arjun Singh Ch V Narasimhaji Rabinarayan Acharya Sujeet K Mishra Source Type: research

Assessment of the Heart's Left and Right Ventricles (EF and TAPSE) in CABG Surgery Patients before and after Cardiac Rehabilitation
CONCLUSION: Completion of a cardiac rehabilitation program leads to significant improvement in left ventricular function, while the improvement in right ventricular function is relatively modest. Moreover, a significant proportion of patients were able to resume their normal daily activities after completing the rehabilitation phase.PMID:37921164 | DOI:10.2174/011871529X250233231017043628 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - November 3, 2023 Category: Drugs & Pharmacology Authors: Mahdi Zahedi Fahime Safi Source Type: research

Decentralization and Virtualization of INR-based Anticoagulation Control During the COVID-19 Pandemic
CONCLUSION: Decentralization and virtualization of the INR clinic have similar TTR results if conducted properly.PMID:37921213 | DOI:10.2174/011871529X242935231026105854 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - November 3, 2023 Category: Drugs & Pharmacology Authors: Abdulrahman Almesned Abdullah Alqwaee Bayan Abusiryeh Ahmad Almeman Source Type: research

Updates in the Pharmacotherapy of Pulmonary Hypertension in Patients with Heart Failure with Preserved Ejection Fraction
Cardiovasc Hematol Disord Drug Targets. 2023 Oct 25. doi: 10.2174/011871529X258234230921112507. Online ahead of print.ABSTRACTPulmonary hypertension (PH) associated with left heart disease (LHD) is a complex cardiopulmonary condition where a variable degree of pulmonary congestion, arterial vasoconstriction and vascular remodeling can lead to PH and right heart strain. Right heart dysfunction has a significant prognostic impact on these patients. Therefore, preserving right ventricular (RV) function is an important treatment goal. However, the treatment of PH in patients with left heart disease has produced conflicting evi...
Source: Cardiovascular and Hematological Disorders Drug Targets - November 3, 2023 Category: Drugs & Pharmacology Authors: Fernando Segovia Hernando Garcia Haider Alkhateeb Debabrata Mukherjee Nils Nickel Source Type: research