KIAA1429-mediated RXFP1 attenuates non-small cell lung cancer tumorigenesis via N6-methyladenosine modification
CONCLUSION: Our findings confirmed that the KIAA1429/RXFP1 axis promotes NSCLC tumorigenesis. This is the first study to reveal the inhibitory function of RXFP1 in NSCLC via KIAA1429-mediated m6A-modification. These findings may help identify new biomarkers for targeted NSCLC therapy.PMID:38427468 | DOI:10.3233/CBM-230188 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - March 1, 2024 Category: Cancer & Oncology Authors: Zhixiang Zhang Jipeng Guo Chongwen Gong Sai Wu Yanlei Sun Source Type: research
Identification of key genes and signalling pathways in clear cell renal cell carcinoma: An integrated bioinformatics approach
CONCLUSION: Among 8 hub genes, only the expression levels of VEGFA, LOX, CCND1, and EGF showed a unique expression pattern exclusively in ccRCC on compared to other type of cancers.PMID:38427469 | DOI:10.3233/CBM-230271 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - March 1, 2024 Category: Cancer & Oncology Authors: Vinoth S Satheeswaran Balasubramanian Ekambaram Perumal Kirankumar Santhakumar Source Type: research
Radiomics and artificial intelligence for risk stratification of pulmonary nodules: Ready for primetime?
Cancer Biomark. 2024 Feb 6. doi: 10.3233/CBM-230360. Online ahead of print.ABSTRACTPulmonary nodules are ubiquitously found on computed tomography (CT) imaging either incidentally or via lung cancer screening and require careful diagnostic evaluation and management to both diagnose malignancy when present and avoid unnecessary biopsy of benign lesions. To engage in this complex decision-making, clinicians must first risk stratify pulmonary nodules to determine what the best course of action should be. Recent developments in imaging technology, computer processing power, and artificial intelligence algorithms have yielded r...
Source: Cancer Biomarkers - March 1, 2024 Category: Cancer & Oncology Authors: Roger Y Kim Source Type: research
KIAA1429-mediated RXFP1 attenuates non-small cell lung cancer tumorigenesis via N6-methyladenosine modification
CONCLUSION: Our findings confirmed that the KIAA1429/RXFP1 axis promotes NSCLC tumorigenesis. This is the first study to reveal the inhibitory function of RXFP1 in NSCLC via KIAA1429-mediated m6A-modification. These findings may help identify new biomarkers for targeted NSCLC therapy.PMID:38427468 | DOI:10.3233/CBM-230188 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - March 1, 2024 Category: Cancer & Oncology Authors: Zhixiang Zhang Jipeng Guo Chongwen Gong Sai Wu Yanlei Sun Source Type: research
Identification of key genes and signalling pathways in clear cell renal cell carcinoma: An integrated bioinformatics approach
CONCLUSION: Among 8 hub genes, only the expression levels of VEGFA, LOX, CCND1, and EGF showed a unique expression pattern exclusively in ccRCC on compared to other type of cancers.PMID:38427469 | DOI:10.3233/CBM-230271 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - March 1, 2024 Category: Cancer & Oncology Authors: Vinoth S Satheeswaran Balasubramanian Ekambaram Perumal Kirankumar Santhakumar Source Type: research
Radiomics and artificial intelligence for risk stratification of pulmonary nodules: Ready for primetime?
Cancer Biomark. 2024 Feb 6. doi: 10.3233/CBM-230360. Online ahead of print.ABSTRACTPulmonary nodules are ubiquitously found on computed tomography (CT) imaging either incidentally or via lung cancer screening and require careful diagnostic evaluation and management to both diagnose malignancy when present and avoid unnecessary biopsy of benign lesions. To engage in this complex decision-making, clinicians must first risk stratify pulmonary nodules to determine what the best course of action should be. Recent developments in imaging technology, computer processing power, and artificial intelligence algorithms have yielded r...
Source: Cancer Biomarkers - March 1, 2024 Category: Cancer & Oncology Authors: Roger Y Kim Source Type: research
KIAA1429-mediated RXFP1 attenuates non-small cell lung cancer tumorigenesis via N6-methyladenosine modification
CONCLUSION: Our findings confirmed that the KIAA1429/RXFP1 axis promotes NSCLC tumorigenesis. This is the first study to reveal the inhibitory function of RXFP1 in NSCLC via KIAA1429-mediated m6A-modification. These findings may help identify new biomarkers for targeted NSCLC therapy.PMID:38427468 | DOI:10.3233/CBM-230188 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - March 1, 2024 Category: Cancer & Oncology Authors: Zhixiang Zhang Jipeng Guo Chongwen Gong Sai Wu Yanlei Sun Source Type: research
Identification of key genes and signalling pathways in clear cell renal cell carcinoma: An integrated bioinformatics approach
CONCLUSION: Among 8 hub genes, only the expression levels of VEGFA, LOX, CCND1, and EGF showed a unique expression pattern exclusively in ccRCC on compared to other type of cancers.PMID:38427469 | DOI:10.3233/CBM-230271 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - March 1, 2024 Category: Cancer & Oncology Authors: Vinoth S Satheeswaran Balasubramanian Ekambaram Perumal Kirankumar Santhakumar Source Type: research
Radiomics and artificial intelligence for risk stratification of pulmonary nodules: Ready for primetime?
Cancer Biomark. 2024 Feb 6. doi: 10.3233/CBM-230360. Online ahead of print.ABSTRACTPulmonary nodules are ubiquitously found on computed tomography (CT) imaging either incidentally or via lung cancer screening and require careful diagnostic evaluation and management to both diagnose malignancy when present and avoid unnecessary biopsy of benign lesions. To engage in this complex decision-making, clinicians must first risk stratify pulmonary nodules to determine what the best course of action should be. Recent developments in imaging technology, computer processing power, and artificial intelligence algorithms have yielded r...
Source: Cancer Biomarkers - March 1, 2024 Category: Cancer & Oncology Authors: Roger Y Kim Source Type: research
KIAA1429-mediated RXFP1 attenuates non-small cell lung cancer tumorigenesis via N6-methyladenosine modification
CONCLUSION: Our findings confirmed that the KIAA1429/RXFP1 axis promotes NSCLC tumorigenesis. This is the first study to reveal the inhibitory function of RXFP1 in NSCLC via KIAA1429-mediated m6A-modification. These findings may help identify new biomarkers for targeted NSCLC therapy.PMID:38427468 | DOI:10.3233/CBM-230188 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - March 1, 2024 Category: Cancer & Oncology Authors: Zhixiang Zhang Jipeng Guo Chongwen Gong Sai Wu Yanlei Sun Source Type: research
Identification of key genes and signalling pathways in clear cell renal cell carcinoma: An integrated bioinformatics approach
CONCLUSION: Among 8 hub genes, only the expression levels of VEGFA, LOX, CCND1, and EGF showed a unique expression pattern exclusively in ccRCC on compared to other type of cancers.PMID:38427469 | DOI:10.3233/CBM-230271 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - March 1, 2024 Category: Cancer & Oncology Authors: Vinoth S Satheeswaran Balasubramanian Ekambaram Perumal Kirankumar Santhakumar Source Type: research
Radiomics and artificial intelligence for risk stratification of pulmonary nodules: Ready for primetime?
Cancer Biomark. 2024 Feb 6. doi: 10.3233/CBM-230360. Online ahead of print.ABSTRACTPulmonary nodules are ubiquitously found on computed tomography (CT) imaging either incidentally or via lung cancer screening and require careful diagnostic evaluation and management to both diagnose malignancy when present and avoid unnecessary biopsy of benign lesions. To engage in this complex decision-making, clinicians must first risk stratify pulmonary nodules to determine what the best course of action should be. Recent developments in imaging technology, computer processing power, and artificial intelligence algorithms have yielded r...
Source: Cancer Biomarkers - March 1, 2024 Category: Cancer & Oncology Authors: Roger Y Kim Source Type: research
The prognostic and antitumor roles of key genes of ferroptosis in liver hepatocellular cancer and stomach adenocarcinoma
CONCLUSIONS: Our results indicated that ferroptosis-related genes might play an important role in LIHC and STAD and might be risk factors for overall survival in LIHC and STAD.PMID:38393890 | DOI:10.3233/CBM-230114 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - February 23, 2024 Category: Cancer & Oncology Authors: Wenceng Pei Minren Jiang Haiyan Liu Jiahong Song Jian Hu Source Type: research
Identification of Hub genes with prognostic values in colorectal cancer by integrated bioinformatics analysis
CONCLUSION: Overexpression of AURKA, CCNB1, CCNA2 and EXO1 had a better prognosis for CRC and this effect was correlation with gene mutation and infiltration of immune cells.PMID:38393891 | DOI:10.3233/CBM-230113 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - February 23, 2024 Category: Cancer & Oncology Authors: Shan Li Ting Li Yan-Qing Shi Bin-Jie Xu Yu-Yong Deng Xu-Guang Sun Source Type: research
The prognostic and antitumor roles of key genes of ferroptosis in liver hepatocellular cancer and stomach adenocarcinoma
CONCLUSIONS: Our results indicated that ferroptosis-related genes might play an important role in LIHC and STAD and might be risk factors for overall survival in LIHC and STAD.PMID:38393890 | DOI:10.3233/CBM-230114 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - February 23, 2024 Category: Cancer & Oncology Authors: Wenceng Pei Minren Jiang Haiyan Liu Jiahong Song Jian Hu Source Type: research
