Rethinking screening mammography in Japan: next-generation breast cancer screening through breast awareness and supplemental ultrasonography
Breast Cancer. 2023 Oct 12. doi: 10.1007/s12282-023-01506-w. Online ahead of print.ABSTRACTBreast cancer mortality has not been reduced in Japan despite more than 20 years of population-based screening mammography. Screening mammography might not be suitable for Japanese women who often have dense breasts, thus decreasing mammography sensitivity because of masking. The J-START study showed that breast ultrasonography increases the sensitivity and the detection rate for early invasive cancers and lowers the rate of interval cancers for Japanese women in their 40 s. Breast awareness and breast cancer survival are directly co...
Source: Breast Cancer - October 12, 2023 Category: Cancer & Oncology Authors: Takayoshi Uematsu Source Type: research
Psychometric evaluation of the Chinese version of the breast cancer perception scale for community women: a translation and validation study
CONCLUSIONS: The Chinese version of the breast cancer perception scale demonstrated suitable psychometric properties among community women. By evaluating results according to the scale, medical staff can enhance breast cancer prevention awareness and care for community-dwelling women and subsequently implement corresponding modifications.PMID:37828267 | DOI:10.1007/s12282-023-01508-8 (Source: Breast Cancer)
Source: Breast Cancer - October 12, 2023 Category: Cancer & Oncology Authors: Linghui Kong Zhen Yang Chen Zheng Tingting Lu Huijun Zhang Source Type: research
Rethinking screening mammography in Japan: next-generation breast cancer screening through breast awareness and supplemental ultrasonography
Breast Cancer. 2023 Oct 12. doi: 10.1007/s12282-023-01506-w. Online ahead of print.ABSTRACTBreast cancer mortality has not been reduced in Japan despite more than 20 years of population-based screening mammography. Screening mammography might not be suitable for Japanese women who often have dense breasts, thus decreasing mammography sensitivity because of masking. The J-START study showed that breast ultrasonography increases the sensitivity and the detection rate for early invasive cancers and lowers the rate of interval cancers for Japanese women in their 40 s. Breast awareness and breast cancer survival are directly co...
Source: Breast Cancer - October 12, 2023 Category: Cancer & Oncology Authors: Takayoshi Uematsu Source Type: research
Psychometric evaluation of the Chinese version of the breast cancer perception scale for community women: a translation and validation study
CONCLUSIONS: The Chinese version of the breast cancer perception scale demonstrated suitable psychometric properties among community women. By evaluating results according to the scale, medical staff can enhance breast cancer prevention awareness and care for community-dwelling women and subsequently implement corresponding modifications.PMID:37828267 | DOI:10.1007/s12282-023-01508-8 (Source: Breast Cancer)
Source: Breast Cancer - October 12, 2023 Category: Cancer & Oncology Authors: Linghui Kong Zhen Yang Chen Zheng Tingting Lu Huijun Zhang Source Type: research
Rethinking screening mammography in Japan: next-generation breast cancer screening through breast awareness and supplemental ultrasonography
Breast Cancer. 2023 Oct 12. doi: 10.1007/s12282-023-01506-w. Online ahead of print.ABSTRACTBreast cancer mortality has not been reduced in Japan despite more than 20 years of population-based screening mammography. Screening mammography might not be suitable for Japanese women who often have dense breasts, thus decreasing mammography sensitivity because of masking. The J-START study showed that breast ultrasonography increases the sensitivity and the detection rate for early invasive cancers and lowers the rate of interval cancers for Japanese women in their 40 s. Breast awareness and breast cancer survival are directly co...
Source: Breast Cancer - October 12, 2023 Category: Cancer & Oncology Authors: Takayoshi Uematsu Source Type: research
Long-term prognostic value of the GenesWell BCT score in Asian women with hormone receptor-positive/HER2-negative early breast cancer
CONCLUSION: The BCT score can identify patients at low risk for recurrence who may not require adjuvant chemotherapy or extended endocrine therapy, regardless of age.PMID:37812303 | DOI:10.1007/s12282-023-01509-7 (Source: Breast Cancer)
Source: Breast Cancer - October 9, 2023 Category: Cancer & Oncology Authors: Yoshitaka Fujiki Masahiro Kashiwaba Mutsumi Sato Junko Kawano Megumi Teraoka Shuichi Kanemitsu Yoshiaki Rai Tetsuhiko Taira Yoshiaki Sagara Yasuyo Ohi Uiree Jo Young-Won Lee Sae Byul Lee Gyungyub Gong Young Kee Shin Mi Jeong Kwon Yasuaki Sagara Source Type: research
Long-term prognostic value of the GenesWell BCT score in Asian women with hormone receptor-positive/HER2-negative early breast cancer
CONCLUSION: The BCT score can identify patients at low risk for recurrence who may not require adjuvant chemotherapy or extended endocrine therapy, regardless of age.PMID:37812303 | DOI:10.1007/s12282-023-01509-7 (Source: Breast Cancer)
Source: Breast Cancer - October 9, 2023 Category: Cancer & Oncology Authors: Yoshitaka Fujiki Masahiro Kashiwaba Mutsumi Sato Junko Kawano Megumi Teraoka Shuichi Kanemitsu Yoshiaki Rai Tetsuhiko Taira Yoshiaki Sagara Yasuyo Ohi Uiree Jo Young-Won Lee Sae Byul Lee Gyungyub Gong Young Kee Shin Mi Jeong Kwon Yasuaki Sagara Source Type: research
Long-term prognostic value of the GenesWell BCT score in Asian women with hormone receptor-positive/HER2-negative early breast cancer
CONCLUSION: The BCT score can identify patients at low risk for recurrence who may not require adjuvant chemotherapy or extended endocrine therapy, regardless of age.PMID:37812303 | DOI:10.1007/s12282-023-01509-7 (Source: Breast Cancer)
Source: Breast Cancer - October 9, 2023 Category: Cancer & Oncology Authors: Yoshitaka Fujiki Masahiro Kashiwaba Mutsumi Sato Junko Kawano Megumi Teraoka Shuichi Kanemitsu Yoshiaki Rai Tetsuhiko Taira Yoshiaki Sagara Yasuyo Ohi Uiree Jo Young-Won Lee Sae Byul Lee Gyungyub Gong Young Kee Shin Mi Jeong Kwon Yasuaki Sagara Source Type: research
The Japanese Breast Cancer Society Clinical Practice Guidelines for systemic treatment of breast cancer, 2022 edition
Breast Cancer. 2023 Oct 7. doi: 10.1007/s12282-023-01505-x. Online ahead of print.ABSTRACTThe Japanese Breast Cancer Society (JBCS) Clinical Practice Guidelines for systemic treatment of breast cancer were updated to the 2022 edition through a process started in 2018. The updated guidelines consist of 12 background questions (BQs), 33 clinical questions (CQs), and 20 future research questions (FRQs). Multiple outcomes including efficacy and safety were selected in each CQ, and then quantitative and qualitative systematic reviews were conducted to determine the strength of evidence and strength of recommendation, which was ...
Source: Breast Cancer - October 7, 2023 Category: Cancer & Oncology Authors: Mitsuo Terada Aki Ito Yuichiro Kikawa Kei Koizumi Yoichi Naito Tatsunori Shimoi Mikiya Ishihara Takashi Yamanaka Yukinori Ozaki Fumikata Hara Rikiya Nakamura Masaya Hattori Minoru Miyashita Naoto Kondo Tetsuhiro Yoshinami Masahiro Takada Koji Matsumoto Ka Source Type: research
The Japanese Breast Cancer Society Clinical Practice Guidelines for systemic treatment of breast cancer, 2022 edition
Breast Cancer. 2023 Oct 7. doi: 10.1007/s12282-023-01505-x. Online ahead of print.ABSTRACTThe Japanese Breast Cancer Society (JBCS) Clinical Practice Guidelines for systemic treatment of breast cancer were updated to the 2022 edition through a process started in 2018. The updated guidelines consist of 12 background questions (BQs), 33 clinical questions (CQs), and 20 future research questions (FRQs). Multiple outcomes including efficacy and safety were selected in each CQ, and then quantitative and qualitative systematic reviews were conducted to determine the strength of evidence and strength of recommendation, which was ...
Source: Breast Cancer - October 7, 2023 Category: Cancer & Oncology Authors: Mitsuo Terada Aki Ito Yuichiro Kikawa Kei Koizumi Yoichi Naito Tatsunori Shimoi Mikiya Ishihara Takashi Yamanaka Yukinori Ozaki Fumikata Hara Rikiya Nakamura Masaya Hattori Minoru Miyashita Naoto Kondo Tetsuhiro Yoshinami Masahiro Takada Koji Matsumoto Ka Source Type: research
Histological spatial analysis on the induction of PD-L1 < sup > + < /sup > macrophages by CD8 < sup > + < /sup > T cells at the marginal microenvironment of triple-negative breast cancer
CONCLUSION: At the marginal microenvironment of TNBC, PD-L1 expression would be induced in MΦs by interaction with CD8+ T cells through CCL2. The interaction between PD-L1+ MΦs and TNBC cells would facilitate the growth of TNBC under antitumor immunity. These interactions would be potential targets for restoring antitumor immunity and suppressing TNBC progression.PMID:37792212 | DOI:10.1007/s12282-023-01507-9 (Source: Breast Cancer)
Source: Breast Cancer - October 4, 2023 Category: Cancer & Oncology Authors: Kazushi Suzuki Rintaro Ohe Takanobu Kabasawa Takumi Kitaoka Masaaki Kawai Fuyuhiko Motoi Mitsuru Futakuchi Source Type: research
Histological spatial analysis on the induction of PD-L1 < sup > + < /sup > macrophages by CD8 < sup > + < /sup > T cells at the marginal microenvironment of triple-negative breast cancer
CONCLUSION: At the marginal microenvironment of TNBC, PD-L1 expression would be induced in MΦs by interaction with CD8+ T cells through CCL2. The interaction between PD-L1+ MΦs and TNBC cells would facilitate the growth of TNBC under antitumor immunity. These interactions would be potential targets for restoring antitumor immunity and suppressing TNBC progression.PMID:37792212 | DOI:10.1007/s12282-023-01507-9 (Source: Breast Cancer)
Source: Breast Cancer - October 4, 2023 Category: Cancer & Oncology Authors: Kazushi Suzuki Rintaro Ohe Takanobu Kabasawa Takumi Kitaoka Masaaki Kawai Fuyuhiko Motoi Mitsuru Futakuchi Source Type: research
Histological spatial analysis on the induction of PD-L1 < sup > + < /sup > macrophages by CD8 < sup > + < /sup > T cells at the marginal microenvironment of triple-negative breast cancer
CONCLUSION: At the marginal microenvironment of TNBC, PD-L1 expression would be induced in MΦs by interaction with CD8+ T cells through CCL2. The interaction between PD-L1+ MΦs and TNBC cells would facilitate the growth of TNBC under antitumor immunity. These interactions would be potential targets for restoring antitumor immunity and suppressing TNBC progression.PMID:37792212 | DOI:10.1007/s12282-023-01507-9 (Source: Breast Cancer)
Source: Breast Cancer - October 4, 2023 Category: Cancer & Oncology Authors: Kazushi Suzuki Rintaro Ohe Takanobu Kabasawa Takumi Kitaoka Masaaki Kawai Fuyuhiko Motoi Mitsuru Futakuchi Source Type: research
Predictive factors for response to neoadjuvant chemotherapy: inflammatory and immune markers in triple-negative breast cancer
CONCLUSIONS: TILs, NLR, and PLR predicted NAC efficacy against TNBC. TIL level was associated with NLR and PLR. NLR was an independent predictive factor and may be a useful surrogate marker for TILs when predicting pCR.PMID:37782377 | DOI:10.1007/s12282-023-01504-y (Source: Breast Cancer)
Source: Breast Cancer - October 2, 2023 Category: Cancer & Oncology Authors: Hiroki Kusama Nobuyoshi Kittaka Ai Soma Azusa Taniguchi Haruka Kanaoka Satomi Nakajima Yuri Oyama Yukiko Seto Jun Okuno Noriyuki Watanabe Saki Matsui Minako Nishio Fumie Fujisawa Keiichiro Honma Yasuhiro Tamaki Takahiro Nakayama Source Type: research
Predictive factors for response to neoadjuvant chemotherapy: inflammatory and immune markers in triple-negative breast cancer
CONCLUSIONS: TILs, NLR, and PLR predicted NAC efficacy against TNBC. TIL level was associated with NLR and PLR. NLR was an independent predictive factor and may be a useful surrogate marker for TILs when predicting pCR.PMID:37782377 | DOI:10.1007/s12282-023-01504-y (Source: Breast Cancer)
Source: Breast Cancer - October 2, 2023 Category: Cancer & Oncology Authors: Hiroki Kusama Nobuyoshi Kittaka Ai Soma Azusa Taniguchi Haruka Kanaoka Satomi Nakajima Yuri Oyama Yukiko Seto Jun Okuno Noriyuki Watanabe Saki Matsui Minako Nishio Fumie Fujisawa Keiichiro Honma Yasuhiro Tamaki Takahiro Nakayama Source Type: research
