Comment on 'An increase in tumor-infiltrating lymphocytes after treatment is significantly associated with a poor response to neoadjuvant endocrine therapy for estrogen receptor-positive/HER2-negative breast cancers' by Fukui et al
Breast Cancer. 2023 Nov 20. doi: 10.1007/s12282-023-01527-5. Online ahead of print.ABSTRACTThis is a comment on the article by Fukui et al. investigating the relationship between tumor-infiltrating lymphocytes (TILs) and response to neoadjuvant endocrine therapy in estrogen receptor-positive/HER2-negative breast cancer. While their data are quite interesting, some information crucial for interpreting the results of this study is missing. Therefore, I would like the authors to provide additional data.PMID:37985622 | DOI:10.1007/s12282-023-01527-5 (Source: Breast Cancer)
Source: Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Yoshiya Horimoto Source Type: research
Medical care costs according to the stage and subtype of breast cancer in a municipal setting: a case study of Hachioji City, Japan
CONCLUSIONS: The results suggest that the early detection of breast cancer may reduce medical care costs at the patient level.PMID:37982959 | DOI:10.1007/s12282-023-01517-7 (Source: Breast Cancer)
Source: Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Yoshitaka Nishikawa Nobukazu Agatsuma Takahiro Utsumi Taro Funakoshi Yukiko Mori Yuki Nakamura Nobuaki Hoshino Takahiro Horimatsu Takumi Saito Soichiro Kashihara Jun Fukuyoshi Rei Goto Masakazu Toi Yoshimitsu Takahashi Takeo Nakayama Source Type: research
Comment on 'An increase in tumor-infiltrating lymphocytes after treatment is significantly associated with a poor response to neoadjuvant endocrine therapy for estrogen receptor-positive/HER2-negative breast cancers' by Fukui et al
Breast Cancer. 2023 Nov 20. doi: 10.1007/s12282-023-01527-5. Online ahead of print.ABSTRACTThis is a comment on the article by Fukui et al. investigating the relationship between tumor-infiltrating lymphocytes (TILs) and response to neoadjuvant endocrine therapy in estrogen receptor-positive/HER2-negative breast cancer. While their data are quite interesting, some information crucial for interpreting the results of this study is missing. Therefore, I would like the authors to provide additional data.PMID:37985622 | DOI:10.1007/s12282-023-01527-5 (Source: Breast Cancer)
Source: Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Yoshiya Horimoto Source Type: research
Medical care costs according to the stage and subtype of breast cancer in a municipal setting: a case study of Hachioji City, Japan
CONCLUSIONS: The results suggest that the early detection of breast cancer may reduce medical care costs at the patient level.PMID:37982959 | DOI:10.1007/s12282-023-01517-7 (Source: Breast Cancer)
Source: Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Yoshitaka Nishikawa Nobukazu Agatsuma Takahiro Utsumi Taro Funakoshi Yukiko Mori Yuki Nakamura Nobuaki Hoshino Takahiro Horimatsu Takumi Saito Soichiro Kashihara Jun Fukuyoshi Rei Goto Masakazu Toi Yoshimitsu Takahashi Takeo Nakayama Source Type: research
Comment on 'An increase in tumor-infiltrating lymphocytes after treatment is significantly associated with a poor response to neoadjuvant endocrine therapy for estrogen receptor-positive/HER2-negative breast cancers' by Fukui et al
Breast Cancer. 2023 Nov 20. doi: 10.1007/s12282-023-01527-5. Online ahead of print.ABSTRACTThis is a comment on the article by Fukui et al. investigating the relationship between tumor-infiltrating lymphocytes (TILs) and response to neoadjuvant endocrine therapy in estrogen receptor-positive/HER2-negative breast cancer. While their data are quite interesting, some information crucial for interpreting the results of this study is missing. Therefore, I would like the authors to provide additional data.PMID:37985622 | DOI:10.1007/s12282-023-01527-5 (Source: Breast Cancer)
Source: Breast Cancer - November 20, 2023 Category: Cancer & Oncology Authors: Yoshiya Horimoto Source Type: research
IDO-1 impairs antitumor immunity of natural killer cells in triple-negative breast cancer via up-regulation of HLA-G
CONCLUSION: TNBC cells induce dysfunction of NK cells through an IFN-γ/IDO-1/HLA-G pathway, which provide novel insights into the mechanisms of TNBC progression and demonstrate the applicability of IDO-1 and HLA-G targeting in the treatment of TNBC.PMID:37981615 | DOI:10.1007/s12282-023-01522-w (Source: Breast Cancer)
Source: Breast Cancer - November 19, 2023 Category: Cancer & Oncology Authors: Rui Jing Shukun Bai Peipei Zhang Hao Ren Lintao Jia Weimiao Li Guoxu Zheng Source Type: research
IDO-1 impairs antitumor immunity of natural killer cells in triple-negative breast cancer via up-regulation of HLA-G
CONCLUSION: TNBC cells induce dysfunction of NK cells through an IFN-γ/IDO-1/HLA-G pathway, which provide novel insights into the mechanisms of TNBC progression and demonstrate the applicability of IDO-1 and HLA-G targeting in the treatment of TNBC.PMID:37981615 | DOI:10.1007/s12282-023-01522-w (Source: Breast Cancer)
Source: Breast Cancer - November 19, 2023 Category: Cancer & Oncology Authors: Rui Jing Shukun Bai Peipei Zhang Hao Ren Lintao Jia Weimiao Li Guoxu Zheng Source Type: research
The Japanese breast cancer society clinical practice guidelines for breast cancer screening and diagnosis, 2022 edition
This article provides updates to readers based on the newly published Japanese Breast Cancer Society Clinical Practice Guidelines for Breast Cancer Screening and Diagnosis, 2022 Edition. These guidelines incorporate the latest evaluation of evidence from studies of diagnostic accuracy. For each clinical question, outcomes for benefits and harms were established, and qualitative or quantitative systematic reviews were conducted. Recommendations were determined through voting by a multidisciplinary group, and guidelines were documented to facilitate shared decision-making among patients and medical professionals. The guideli...
Source: Breast Cancer - November 16, 2023 Category: Cancer & Oncology Authors: Kazunori Kubota Kazutaka Nakashima Kazuaki Nakashima Masako Kataoka Kenich Inoue Mariko Goto Chizuko Kanbayashi Koichi Hirokaga Ken Yamaguchi Akihiko Suzuki Source Type: research
Hepatitis C virus may accelerate breast cancer progression by increasing mutant p53 and c-Myc oncoproteins circulating levels
CONCLUSIONS: This study concluded that HCV infection may be accompanied with BC severity behavior and this may be owing to elevated expression of mutant p53 and c-Myc oncoproteins.PMID:37973687 | DOI:10.1007/s12282-023-01519-5 (Source: Breast Cancer)
Source: Breast Cancer - November 16, 2023 Category: Cancer & Oncology Authors: Amira Fathy Mohamed A Abdelrazek Abdelfattah M Attallah Amr Abouzid Mohamed El-Far Source Type: research
The Japanese breast cancer society clinical practice guidelines for breast cancer screening and diagnosis, 2022 edition
This article provides updates to readers based on the newly published Japanese Breast Cancer Society Clinical Practice Guidelines for Breast Cancer Screening and Diagnosis, 2022 Edition. These guidelines incorporate the latest evaluation of evidence from studies of diagnostic accuracy. For each clinical question, outcomes for benefits and harms were established, and qualitative or quantitative systematic reviews were conducted. Recommendations were determined through voting by a multidisciplinary group, and guidelines were documented to facilitate shared decision-making among patients and medical professionals. The guideli...
Source: Breast Cancer - November 16, 2023 Category: Cancer & Oncology Authors: Kazunori Kubota Kazutaka Nakashima Kazuaki Nakashima Masako Kataoka Kenich Inoue Mariko Goto Chizuko Kanbayashi Koichi Hirokaga Ken Yamaguchi Akihiko Suzuki Source Type: research
Hepatitis C virus may accelerate breast cancer progression by increasing mutant p53 and c-Myc oncoproteins circulating levels
CONCLUSIONS: This study concluded that HCV infection may be accompanied with BC severity behavior and this may be owing to elevated expression of mutant p53 and c-Myc oncoproteins.PMID:37973687 | DOI:10.1007/s12282-023-01519-5 (Source: Breast Cancer)
Source: Breast Cancer - November 16, 2023 Category: Cancer & Oncology Authors: Amira Fathy Mohamed A Abdelrazek Abdelfattah M Attallah Amr Abouzid Mohamed El-Far Source Type: research
Fatigue and quality of life during neoadjuvant chemotherapy of early breast cancer: a prospective multicenter cohort study
CONCLUSIONS: Further actions to reduce fatigue and improve quality of life during neoadjuvant chemotherapy of early breast cancer are needed. Focus should be laid on the physical dimension. Future research should also investigate the impact of different chemotherapy sequences and densities on fatigue and quality of life.STUDY REGISTRATION: The study was registered in the German Clinical Trials Register in May 2019 (DRKS00016761).PMID:37966690 | DOI:10.1007/s12282-023-01520-y (Source: Breast Cancer)
Source: Breast Cancer - November 15, 2023 Category: Cancer & Oncology Authors: Florian Pelzer Wilfried Tr öger Marcus Reif Susanne Sch önberg David D Martin Cornelia M üller Isabell Utz-Billing Thorsten K ühn Stephan Baumgartner Marion Kiechle Daniela Paepke Source Type: research
Fatigue and quality of life during neoadjuvant chemotherapy of early breast cancer: a prospective multicenter cohort study
CONCLUSIONS: Further actions to reduce fatigue and improve quality of life during neoadjuvant chemotherapy of early breast cancer are needed. Focus should be laid on the physical dimension. Future research should also investigate the impact of different chemotherapy sequences and densities on fatigue and quality of life.STUDY REGISTRATION: The study was registered in the German Clinical Trials Register in May 2019 (DRKS00016761).PMID:37966690 | DOI:10.1007/s12282-023-01520-y (Source: Breast Cancer)
Source: Breast Cancer - November 15, 2023 Category: Cancer & Oncology Authors: Florian Pelzer Wilfried Tr öger Marcus Reif Susanne Sch önberg David D Martin Cornelia M üller Isabell Utz-Billing Thorsten K ühn Stephan Baumgartner Marion Kiechle Daniela Paepke Source Type: research
Fatigue and quality of life during neoadjuvant chemotherapy of early breast cancer: a prospective multicenter cohort study
CONCLUSIONS: Further actions to reduce fatigue and improve quality of life during neoadjuvant chemotherapy of early breast cancer are needed. Focus should be laid on the physical dimension. Future research should also investigate the impact of different chemotherapy sequences and densities on fatigue and quality of life.STUDY REGISTRATION: The study was registered in the German Clinical Trials Register in May 2019 (DRKS00016761).PMID:37966690 | DOI:10.1007/s12282-023-01520-y (Source: Breast Cancer)
Source: Breast Cancer - November 15, 2023 Category: Cancer & Oncology Authors: Florian Pelzer Wilfried Tr öger Marcus Reif Susanne Sch önberg David D Martin Cornelia M üller Isabell Utz-Billing Thorsten K ühn Stephan Baumgartner Marion Kiechle Daniela Paepke Source Type: research
Machine learning applied in patient-reported outcome research-exploring symptoms in adjuvant treatment of breast cancer
CONCLUSION: In conclusion, this explorative data analysis using ML methodologies in an ePRO dataset from a population of women with breast cancer treated with adjuvant chemotherapy unravels that the symptoms aching joints and numbness/tingling could be important for drop out of planned adjuvant chemotherapy.PMID:37940813 | DOI:10.1007/s12282-023-01515-9 (Source: Breast Cancer)
Source: Breast Cancer - November 8, 2023 Category: Cancer & Oncology Authors: Helle Pappot Ben óný P Björnsson Oswin Krause Christina B æksted Pernille E Bidstrup Susanne O Dalton Christoffer Johansen Ann Knoop Ivan Vogelius Cecilie Holl änder-Mieritz Source Type: research
