SIRT1 mediates breast cancer development and tumorigenesis controlled by estrogen-related receptor β
Breast Cancer. 2024 Feb 29. doi: 10.1007/s12282-024-01555-9. Online ahead of print.ABSTRACTSilent mating type information regulation 2 homolog 1 (SIRT1) is a class III histone deacetylase (HDAC) that is NAD + dependent and essential for metabolism, senescence, and cell survival. SIRT1 is overexpressed in several cancers, including breast cancer. SIRT1 is a well-known target gene of the estrogen receptor alpha (ER alpha) and is closely related to ER alpha deacetylation. Transcription factor Estrogen-related receptors (ERRs) share sequence homology with ERs in the DNA-binding domain, therefore, the possibility of sharing tar...
Source: Breast Cancer - February 29, 2024 Category: Cancer & Oncology Authors: Monalisa Parija Surya Prakash B Madhu Krishna Sanghamitra Dash Sandip K Mishra Source Type: research
SIRT1 mediates breast cancer development and tumorigenesis controlled by estrogen-related receptor β
Breast Cancer. 2024 Feb 29. doi: 10.1007/s12282-024-01555-9. Online ahead of print.ABSTRACTSilent mating type information regulation 2 homolog 1 (SIRT1) is a class III histone deacetylase (HDAC) that is NAD + dependent and essential for metabolism, senescence, and cell survival. SIRT1 is overexpressed in several cancers, including breast cancer. SIRT1 is a well-known target gene of the estrogen receptor alpha (ER alpha) and is closely related to ER alpha deacetylation. Transcription factor Estrogen-related receptors (ERRs) share sequence homology with ERs in the DNA-binding domain, therefore, the possibility of sharing tar...
Source: Breast Cancer - February 29, 2024 Category: Cancer & Oncology Authors: Monalisa Parija Surya Prakash B Madhu Krishna Sanghamitra Dash Sandip K Mishra Source Type: research
Outcomes of whole breast radiation therapy in Asian breast cancer patients with prior cosmetic implants
CONCLUSIONS: This study demonstrated a favorable safety profile of WB-RT for treatment of breast cancer in Asian women with prior-CBI. The integration of HF-RT following BCS was thought to be a feasible approach.PMID:38368487 | DOI:10.1007/s12282-024-01547-9 (Source: Breast Cancer)
Source: Breast Cancer - February 17, 2024 Category: Cancer & Oncology Authors: Nalee Kim Won Kyung Cho Won Park Jeong Eon Lee Seok Jin Nam Seok Won Kim Jonghan Yu Byung Joo Chae Sei Kyung Lee Jai-Min Ryu Eun Sook Ko Haeyoung Kim Source Type: research
Outcomes of whole breast radiation therapy in Asian breast cancer patients with prior cosmetic implants
CONCLUSIONS: This study demonstrated a favorable safety profile of WB-RT for treatment of breast cancer in Asian women with prior-CBI. The integration of HF-RT following BCS was thought to be a feasible approach.PMID:38368487 | DOI:10.1007/s12282-024-01547-9 (Source: Breast Cancer)
Source: Breast Cancer - February 17, 2024 Category: Cancer & Oncology Authors: Nalee Kim Won Kyung Cho Won Park Jeong Eon Lee Seok Jin Nam Seok Won Kim Jonghan Yu Byung Joo Chae Sei Kyung Lee Jai-Min Ryu Eun Sook Ko Haeyoung Kim Source Type: research
Outcomes of whole breast radiation therapy in Asian breast cancer patients with prior cosmetic implants
CONCLUSIONS: This study demonstrated a favorable safety profile of WB-RT for treatment of breast cancer in Asian women with prior-CBI. The integration of HF-RT following BCS was thought to be a feasible approach.PMID:38368487 | DOI:10.1007/s12282-024-01547-9 (Source: Breast Cancer)
Source: Breast Cancer - February 17, 2024 Category: Cancer & Oncology Authors: Nalee Kim Won Kyung Cho Won Park Jeong Eon Lee Seok Jin Nam Seok Won Kim Jonghan Yu Byung Joo Chae Sei Kyung Lee Jai-Min Ryu Eun Sook Ko Haeyoung Kim Source Type: research
Outcomes of whole breast radiation therapy in Asian breast cancer patients with prior cosmetic implants
CONCLUSIONS: This study demonstrated a favorable safety profile of WB-RT for treatment of breast cancer in Asian women with prior-CBI. The integration of HF-RT following BCS was thought to be a feasible approach.PMID:38368487 | DOI:10.1007/s12282-024-01547-9 (Source: Breast Cancer)
Source: Breast Cancer - February 17, 2024 Category: Cancer & Oncology Authors: Nalee Kim Won Kyung Cho Won Park Jeong Eon Lee Seok Jin Nam Seok Won Kim Jonghan Yu Byung Joo Chae Sei Kyung Lee Jai-Min Ryu Eun Sook Ko Haeyoung Kim Source Type: research
Outcomes of whole breast radiation therapy in Asian breast cancer patients with prior cosmetic implants
CONCLUSIONS: This study demonstrated a favorable safety profile of WB-RT for treatment of breast cancer in Asian women with prior-CBI. The integration of HF-RT following BCS was thought to be a feasible approach.PMID:38368487 | DOI:10.1007/s12282-024-01547-9 (Source: Breast Cancer)
Source: Breast Cancer - February 17, 2024 Category: Cancer & Oncology Authors: Nalee Kim Won Kyung Cho Won Park Jeong Eon Lee Seok Jin Nam Seok Won Kim Jonghan Yu Byung Joo Chae Sei Kyung Lee Jai-Min Ryu Eun Sook Ko Haeyoung Kim Source Type: research
Outcomes of whole breast radiation therapy in Asian breast cancer patients with prior cosmetic implants
CONCLUSIONS: This study demonstrated a favorable safety profile of WB-RT for treatment of breast cancer in Asian women with prior-CBI. The integration of HF-RT following BCS was thought to be a feasible approach.PMID:38368487 | DOI:10.1007/s12282-024-01547-9 (Source: Breast Cancer)
Source: Breast Cancer - February 17, 2024 Category: Cancer & Oncology Authors: Nalee Kim Won Kyung Cho Won Park Jeong Eon Lee Seok Jin Nam Seok Won Kim Jonghan Yu Byung Joo Chae Sei Kyung Lee Jai-Min Ryu Eun Sook Ko Haeyoung Kim Source Type: research
Outcomes of whole breast radiation therapy in Asian breast cancer patients with prior cosmetic implants
CONCLUSIONS: This study demonstrated a favorable safety profile of WB-RT for treatment of breast cancer in Asian women with prior-CBI. The integration of HF-RT following BCS was thought to be a feasible approach.PMID:38368487 | DOI:10.1007/s12282-024-01547-9 (Source: Breast Cancer)
Source: Breast Cancer - February 17, 2024 Category: Cancer & Oncology Authors: Nalee Kim Won Kyung Cho Won Park Jeong Eon Lee Seok Jin Nam Seok Won Kim Jonghan Yu Byung Joo Chae Sei Kyung Lee Jai-Min Ryu Eun Sook Ko Haeyoung Kim Source Type: research
Outcomes of whole breast radiation therapy in Asian breast cancer patients with prior cosmetic implants
CONCLUSIONS: This study demonstrated a favorable safety profile of WB-RT for treatment of breast cancer in Asian women with prior-CBI. The integration of HF-RT following BCS was thought to be a feasible approach.PMID:38368487 | DOI:10.1007/s12282-024-01547-9 (Source: Breast Cancer)
Source: Breast Cancer - February 17, 2024 Category: Cancer & Oncology Authors: Nalee Kim Won Kyung Cho Won Park Jeong Eon Lee Seok Jin Nam Seok Won Kim Jonghan Yu Byung Joo Chae Sei Kyung Lee Jai-Min Ryu Eun Sook Ko Haeyoung Kim Source Type: research
Outcomes of whole breast radiation therapy in Asian breast cancer patients with prior cosmetic implants
CONCLUSIONS: This study demonstrated a favorable safety profile of WB-RT for treatment of breast cancer in Asian women with prior-CBI. The integration of HF-RT following BCS was thought to be a feasible approach.PMID:38368487 | DOI:10.1007/s12282-024-01547-9 (Source: Breast Cancer)
Source: Breast Cancer - February 17, 2024 Category: Cancer & Oncology Authors: Nalee Kim Won Kyung Cho Won Park Jeong Eon Lee Seok Jin Nam Seok Won Kim Jonghan Yu Byung Joo Chae Sei Kyung Lee Jai-Min Ryu Eun Sook Ko Haeyoung Kim Source Type: research
Preliminary report on ultrashort perioperative partial-breast irradiation with multicatheter interstitial brachytherapy for early-stage breast cancer
CONCLUSIONS: Although this preliminary report included a small sample size and had a short follow-up period, the local control and toxicity rates were similar between the uPBI and cPBI groups. Further research is warranted to investigate the ideal dose schedule of MIB-PBI.PMID:38363473 | DOI:10.1007/s12282-024-01546-w (Source: Breast Cancer)
Source: Breast Cancer - February 16, 2024 Category: Cancer & Oncology Authors: Kazuhiko Sato Hiromi Fuchikami Naoko Takeda Nana Natsume Masahiro Kato Source Type: research
Preliminary report on ultrashort perioperative partial-breast irradiation with multicatheter interstitial brachytherapy for early-stage breast cancer
CONCLUSIONS: Although this preliminary report included a small sample size and had a short follow-up period, the local control and toxicity rates were similar between the uPBI and cPBI groups. Further research is warranted to investigate the ideal dose schedule of MIB-PBI.PMID:38363473 | DOI:10.1007/s12282-024-01546-w (Source: Breast Cancer)
Source: Breast Cancer - February 16, 2024 Category: Cancer & Oncology Authors: Kazuhiko Sato Hiromi Fuchikami Naoko Takeda Nana Natsume Masahiro Kato Source Type: research
A novel approach correlating pathologic complete response with digital pathology and radiomics in triple-negative breast cancer
Breast Cancer. 2024 Feb 13. doi: 10.1007/s12282-024-01544-y. Online ahead of print.ABSTRACTThis rapid communication highlights the correlations between digital pathology-whole slide imaging (WSI) and radiomics-magnetic resonance imaging (MRI) features in triple-negative breast cancer (TNBC) patients. The research collected 12 patients who had both core needle biopsy and MRI performed to evaluate pathologic complete response (pCR). The results showed that higher collagenous values in pathology data were correlated with more homogeneity, whereas higher tumor expression values in pathology data correlated with less homogeneit...
Source: Breast Cancer - February 13, 2024 Category: Cancer & Oncology Authors: Sean M Hacking Gabrielle Windsor Robert Cooper Zhicheng Jiao Ana Lourenco Yihong Wang Source Type: research
Clinical benefits of tomosynthesis-guided vacuum assisted breast biopsy: a comparison with stereotactic vacuum assisted biopsy
CONCLUSION: Our study demonstrated that the clinical effectiveness of 3D-VAB is superior to that of 2D-VAB and that the significant reduction in examination time with 3D-VAB is expected to benefit patients.PMID:38324059 | DOI:10.1007/s12282-024-01542-0 (Source: Breast Cancer)
Source: Breast Cancer - February 7, 2024 Category: Cancer & Oncology Authors: Mikiko Kasahara Sayaka Kanematsu Yoshihito Tanaka Satoshi Okazaki Masahiro Watatani Source Type: research
