Impact of neoadjuvant chemotherapy on the safety and long-term outcomes of patients undergoing immediate breast reconstruction after mastectomy
CONCLUSION: IBR after NAC is a safe procedure with an acceptable postoperative complication profile.PMID:38573438 | DOI:10.1007/s12282-024-01570-w (Source: Breast Cancer)
Source: Breast Cancer - April 4, 2024 Category: Cancer & Oncology Authors: Hiroko Nogi Akiko Ogiya Makoto Ishitobi Chikako Yamauchi Hiroki Mori Ayaka Shimo Kazutaka Narui Naomi Nagura Hirohito Seki Shinsuke Sasada Teruhisa Sakurai Tadahiko Shien Collaborative Study Group of Scientific Research of The Japanese Breast Cancer Socie Source Type: research
The Japanese Breast Cancer Society Clinical Practice Guidelines for Breast Cancer, 2022 Edition: changes from the 2018 edition and general statements on breast cancer treatment
Breast Cancer. 2024 Apr 3. doi: 10.1007/s12282-024-01566-6. Online ahead of print.ABSTRACTThe Japanese Breast Cancer Society Clinical Practice Guidelines for Breast Cancer, 2022 Edition was published in June 2022. The guidelines were prepared while conforming as much as possible to the "Minds Manual for Guideline Development 2020 ver. 3.0." edited by the Minds Manual Development Committee of the Japan Council for Quality Health Care in 2021. In addition, a survey of Japanese Breast Cancer Society members on the 2018 edition of the guidelines was conducted from February 19 to March 4, 2021. Based on the responses from over ...
Source: Breast Cancer - April 3, 2024 Category: Cancer & Oncology Authors: Yutaka Yamamoto Chikako Yamauchi Tatsuya Toyama Shigenori Nagai Takehiko Sakai Goro Kutomi Michio Yoshimura Masaaki Kawai Shoichiro Ohtani Kazunori Kubota Kazutaka Nakashima Naoko Honma Masayuki Yoshida Eriko Tokunaga Naruto Taira Hiroji Iwata Shigehira S Source Type: research
Associations of pre-diagnosis physical activity with treatment tolerance and treatment efficacy in breast cancer patients with neoadjuvant chemotherapy
CONCLUSIONS: Although small sample size and limited information on exercise closer to time of diagnosis limit interpretation, pre-diagnosis PA was not convincingly associated with treatment tolerance or treatment efficacy in BCa patients receiving NACT. Future investigations are needed to better understand the impact of pre-diagnosis PA on BCa treatment.PMID:38564089 | DOI:10.1007/s12282-024-01569-3 (Source: Breast Cancer)
Source: Breast Cancer - April 2, 2024 Category: Cancer & Oncology Authors: Dan Lin Kathleen M Sturgeon Joshua E Muscat Shouhao Zhou Andrea L Hobkirk Katie M O'Brien Dale P Sandler Cheryl L Thompson Source Type: research
Associations of pre-diagnosis physical activity with treatment tolerance and treatment efficacy in breast cancer patients with neoadjuvant chemotherapy
CONCLUSIONS: Although small sample size and limited information on exercise closer to time of diagnosis limit interpretation, pre-diagnosis PA was not convincingly associated with treatment tolerance or treatment efficacy in BCa patients receiving NACT. Future investigations are needed to better understand the impact of pre-diagnosis PA on BCa treatment.PMID:38564089 | DOI:10.1007/s12282-024-01569-3 (Source: Breast Cancer)
Source: Breast Cancer - April 2, 2024 Category: Cancer & Oncology Authors: Dan Lin Kathleen M Sturgeon Joshua E Muscat Shouhao Zhou Andrea L Hobkirk Katie M O'Brien Dale P Sandler Cheryl L Thompson Source Type: research
The correlation study between TOP2A gene expression in circulating tumor cells and chemotherapeutic drug resistance of patients with breast cancer
CONCLUSIONS: High TCTC, HCTCs, and positive TOP2A gene expression on CTCs were critical biomarkers for predicting outcomes of BC patients. Positive hormone receptor expression in BC patients has significant favor PFS.PMID:38561479 | DOI:10.1007/s12282-024-01553-x (Source: Breast Cancer)
Source: Breast Cancer - April 1, 2024 Category: Cancer & Oncology Authors: Jin-Hui Ye Jian Yu Ming-Ying Huang Yue-Mei Mo Source Type: research
The correlation study between TOP2A gene expression in circulating tumor cells and chemotherapeutic drug resistance of patients with breast cancer
CONCLUSIONS: High TCTC, HCTCs, and positive TOP2A gene expression on CTCs were critical biomarkers for predicting outcomes of BC patients. Positive hormone receptor expression in BC patients has significant favor PFS.PMID:38561479 | DOI:10.1007/s12282-024-01553-x (Source: Breast Cancer)
Source: Breast Cancer - April 1, 2024 Category: Cancer & Oncology Authors: Jin-Hui Ye Jian Yu Ming-Ying Huang Yue-Mei Mo Source Type: research
Prospects for liquid biopsy using microRNA and extracellular vesicles in breast cancer
Breast Cancer. 2024 Mar 30. doi: 10.1007/s12282-024-01563-9. Online ahead of print.ABSTRACTAmong the analytes circulating in body fluids, microRNAs, a type of non-coding RNA and known to exist 2655 in primates, have attracted attention as a novel biomarker for cancer screening. MicroRNAs are signaling molecules with important gene expression regulatory functions that can simultaneously control many gene functions and multiple different pathways in living organisms. These microRNAs are transported in extracellular vesicles (EVs), which are lipid bilayers with 50-150 nm in diameter, and are used as communication tools betwee...
Source: Breast Cancer - March 30, 2024 Category: Cancer & Oncology Authors: Takahiro Ochiya Kazuki Hashimoto Akihiko Shimomura Source Type: research
Prospects for liquid biopsy using microRNA and extracellular vesicles in breast cancer
Breast Cancer. 2024 Mar 30. doi: 10.1007/s12282-024-01563-9. Online ahead of print.ABSTRACTAmong the analytes circulating in body fluids, microRNAs, a type of non-coding RNA and known to exist 2655 in primates, have attracted attention as a novel biomarker for cancer screening. MicroRNAs are signaling molecules with important gene expression regulatory functions that can simultaneously control many gene functions and multiple different pathways in living organisms. These microRNAs are transported in extracellular vesicles (EVs), which are lipid bilayers with 50-150 nm in diameter, and are used as communication tools betwee...
Source: Breast Cancer - March 30, 2024 Category: Cancer & Oncology Authors: Takahiro Ochiya Kazuki Hashimoto Akihiko Shimomura Source Type: research
Prognosis of primary breast salivary gland-type carcinoma: a propensity score-matching analysis with invasive carcinoma of no special type based on the SEER database for years 2010-2020
CONCLUSIONS: This study suggests that when managing primary breast salivary gland-type carcinoma, greater emphasis should be given to the tumor grade and AJCC stage group in addition to acinic cell carcinoma histological type and HER2 overexpression. Conventional prognostic factors are important as salivary gland-type carcinoma had similar prognosis as invasive carcinoma, NST, following adjustment for confounding variables.PMID:38546966 | DOI:10.1007/s12282-024-01564-8 (Source: Breast Cancer)
Source: Breast Cancer - March 28, 2024 Category: Cancer & Oncology Authors: Ewe Seng Ch'ng Source Type: research
Prognosis of primary breast salivary gland-type carcinoma: a propensity score-matching analysis with invasive carcinoma of no special type based on the SEER database for years 2010-2020
CONCLUSIONS: This study suggests that when managing primary breast salivary gland-type carcinoma, greater emphasis should be given to the tumor grade and AJCC stage group in addition to acinic cell carcinoma histological type and HER2 overexpression. Conventional prognostic factors are important as salivary gland-type carcinoma had similar prognosis as invasive carcinoma, NST, following adjustment for confounding variables.PMID:38546966 | DOI:10.1007/s12282-024-01564-8 (Source: Breast Cancer)
Source: Breast Cancer - March 28, 2024 Category: Cancer & Oncology Authors: Ewe Seng Ch'ng Source Type: research
Prognosis of primary breast salivary gland-type carcinoma: a propensity score-matching analysis with invasive carcinoma of no special type based on the SEER database for years 2010-2020
CONCLUSIONS: This study suggests that when managing primary breast salivary gland-type carcinoma, greater emphasis should be given to the tumor grade and AJCC stage group in addition to acinic cell carcinoma histological type and HER2 overexpression. Conventional prognostic factors are important as salivary gland-type carcinoma had similar prognosis as invasive carcinoma, NST, following adjustment for confounding variables.PMID:38546966 | DOI:10.1007/s12282-024-01564-8 (Source: Breast Cancer)
Source: Breast Cancer - March 28, 2024 Category: Cancer & Oncology Authors: Ewe Seng Ch'ng Source Type: research
Liquid biopsy using non-coding RNAs and extracellular vesicles for breast cancer management
This article examines liquid biopsy using non-coding RNAs and extracellular vesicles in detail. Liquid biopsy is emerging as a prominent non-invasive diagnostic tool in the treatment of breast cancer. We will elucidate the roles of these molecules in early detection, monitoring treatment effectiveness, and prognostic assessment of breast cancer. Additionally, the clinical significance of these molecules will be discussed. We aim to delve into the distinct characteristics of these molecules and their possible roles in breast cancer management, with an anticipation of their contribution to future diagnostic and therapeutic a...
Source: Breast Cancer - March 21, 2024 Category: Cancer & Oncology Authors: Kazuki Hashimoto Takahiro Ochiya Akihiko Shimomura Source Type: research
Endoscopic mastectomy followed by immediate breast reconstruction with fat grafting for breast cancer
CONCLUSION: To the best of our knowledge, this is the first report of endoscopic mastectomy with immediate FG for reconstruction. When compared with other immediate autologous reconstructions, our strategy could minimize the skin incision and procedure duration, as well as limit complications. Further prospective investigations are needed to evaluate oncological safety, surgical outcomes, and patient satisfaction.PMID:38512534 | DOI:10.1007/s12282-024-01561-x (Source: Breast Cancer)
Source: Breast Cancer - March 21, 2024 Category: Cancer & Oncology Authors: Kazutaka Narui Toshihiko Satake Takashi Ishikawa Mayu Muto Yui Tsunoda Akimitsu Yamada Kei Kawashima Natsuki Uenaka Yoshie Fujiwara Masanori Oshi Shoko Adachi Chiho Suzuki Tomoko Wada Shinya Yamamoto Mikiko Tanabe Jiro Maegawa Itaru Endo Source Type: research
Liquid biopsy using non-coding RNAs and extracellular vesicles for breast cancer management
This article examines liquid biopsy using non-coding RNAs and extracellular vesicles in detail. Liquid biopsy is emerging as a prominent non-invasive diagnostic tool in the treatment of breast cancer. We will elucidate the roles of these molecules in early detection, monitoring treatment effectiveness, and prognostic assessment of breast cancer. Additionally, the clinical significance of these molecules will be discussed. We aim to delve into the distinct characteristics of these molecules and their possible roles in breast cancer management, with an anticipation of their contribution to future diagnostic and therapeutic a...
Source: Breast Cancer - March 21, 2024 Category: Cancer & Oncology Authors: Kazuki Hashimoto Takahiro Ochiya Akihiko Shimomura Source Type: research
Endoscopic mastectomy followed by immediate breast reconstruction with fat grafting for breast cancer
CONCLUSION: To the best of our knowledge, this is the first report of endoscopic mastectomy with immediate FG for reconstruction. When compared with other immediate autologous reconstructions, our strategy could minimize the skin incision and procedure duration, as well as limit complications. Further prospective investigations are needed to evaluate oncological safety, surgical outcomes, and patient satisfaction.PMID:38512534 | DOI:10.1007/s12282-024-01561-x (Source: Breast Cancer)
Source: Breast Cancer - March 21, 2024 Category: Cancer & Oncology Authors: Kazutaka Narui Toshihiko Satake Takashi Ishikawa Mayu Muto Yui Tsunoda Akimitsu Yamada Kei Kawashima Natsuki Uenaka Yoshie Fujiwara Masanori Oshi Shoko Adachi Chiho Suzuki Tomoko Wada Shinya Yamamoto Mikiko Tanabe Jiro Maegawa Itaru Endo Source Type: research
