Survival trends and patient characteristics between 2004 and 2016 for breast cancer in Japan based on the National Clinical Database-Breast Cancer Registry
Breast Cancer. 2024 Feb 6. doi: 10.1007/s12282-024-01545-x. Online ahead of print.ABSTRACTThis is a prognostic report by the Japanese Breast Cancer Society on breast cancer extracted from the National Clinical Database-Breast Cancer Registry of Japan. Here, we present a summary of 457,878 breast cancer cases registered between 2004 and 2016. The median follow-up duration was 5.6 years. The median age at the start of treatment was 59 years (5-95%: 38-82 years) and increased from 57 years between 2004 and 2008 to 60 years between 2013 and 2016. The proportion of patients with Stage 0-II disease increased from 74.5% to 78.3%....
Source: Breast Cancer - February 6, 2024 Category: Cancer & Oncology Authors: Takayuki Iwamoto Hiraku Kumamaru Naoki Niikura Yasuaki Sagara Minoru Miyashita Takaaki Konishi Naoko Sanuki Kenta Tanakura Masayuki Nagahashi Naoki Hayashi Masayuki Yoshida Chie Watanabe Naoko Kinukawa Masakazu Toi Shigehira Saji Source Type: research
Advances in the study of autophagy in breast cancer
Breast Cancer. 2024 Feb 5. doi: 10.1007/s12282-023-01541-7. Online ahead of print.ABSTRACTBreast cancer is the most prevalent malignant tumor among women, with a high incidence and mortality rate all year round, which seriously affects women's health. Autophagy, a well-conserved cellular process inherent in eukaryotic organisms, plays a pivotal role in degrading damaged proteins and organelles, recycling their breakdown products to aid cells in navigating stress and gradually restoring homeostatic equilibrium. Recent studies have unveiled the intricate connection between autophagy and breast cancer. Autophagy is a double-e...
Source: Breast Cancer - February 5, 2024 Category: Cancer & Oncology Authors: Tang Yu Liu Rui Zhao Jiumei Li Ziwei Hu Ying Source Type: research
Expression and clinical significance of hypoxia-induced long non-coding RNA TCONS_I2_00001955 in breast cancer
CONCLUSION: Hypoxia-induced lncRNA TCONS_I2_00001955 was associated with aggressive feature and poor prognosis of breast cancer.PMID:38310620 | DOI:10.1007/s12282-023-01540-8 (Source: Breast Cancer)
Source: Breast Cancer - February 4, 2024 Category: Cancer & Oncology Authors: Jie-Yin Zhuang Ze-Nan Huang Zi-Jin Weng Meng-Meng Liu Xiang-Qi Huang Dan He Chun-Kui Shao Min Dong Source Type: research
Patient-reported outcomes of mesh in minimally invasive (laparoscopic/robot-assisted) immediate subpectoral prosthesis breast reconstruction: a retrospective study
CONCLUSIONS: Mesh-assisted minimally invasive NSM-PBR has good aesthetic outcomes and high patient satisfaction. There were no significant differences in complication rates between the mesh-assisted and non-mesh-assisted groups.PMID:38306013 | DOI:10.1007/s12282-023-01529-3 (Source: Breast Cancer)
Source: Breast Cancer - February 2, 2024 Category: Cancer & Oncology Authors: Xin Wu Yu Gui Jing Liu Shichao Li Xi Yang Zhen Zeng Yi Zhang Linjun Fan Jun Jiang Li Chen Source Type: research
Neoadjuvant nivolumab plus bevacizumab therapy improves the prognosis of triple-negative breast cancer in humanized mouse models
CONCLUSION: The preclinical study has demonstrated the therapeutic efficacy and mechanism of neoadjuvant combination therapy (nivolumab plus bevacizumab) in treating early TNBC.PMID:38289410 | DOI:10.1007/s12282-024-01543-z (Source: Breast Cancer)
Source: Breast Cancer - January 30, 2024 Category: Cancer & Oncology Authors: Hongyan Zheng Lihua Wu Jianfeng Chen Na Na Ge Lou Source Type: research
Endosomal protein expression of γ1-adaptin is associated with tumor growth activity and relapse-free survival in breast cancer
CONCLUSION: These results suggest that the endosomal expression of γ1-adaptin is positively correlated with breast cancer malignancy and could be a novel prognostic marker.PMID:38265632 | DOI:10.1007/s12282-023-01539-1 (Source: Breast Cancer)
Source: Breast Cancer - January 24, 2024 Category: Cancer & Oncology Authors: Nobuhiro Hoshi Takefumi Uemura Kazunoshin Tachibana Sadahiko Abe Yuko Murakami-Nishimagi Maiko Okano Masaru Noda Katsuharu Saito Koji Kono Tohru Ohtake Satoshi Waguri Source Type: research
Clinicopathological differences and survival benefit in ER+/PR+/HER2+ vs ER+/PR-/HER2+ breast cancer subtypes
CONCLUSIONS: HER2-positive breast cancers with different HR statuses exhibit distinct clinicopathological features and survival outcomes. Patients in the ER+/PR+/HER2+ group generally experience better survival, particularly in postmenopausal and pN0 stage patients. Treatment strategies should consider HR status and specific modalities for better personalized management.PMID:38231460 | DOI:10.1007/s12282-023-01538-2 (Source: Breast Cancer)
Source: Breast Cancer - January 17, 2024 Category: Cancer & Oncology Authors: Wu Ding Dengfeng Ye Haifeng Chen Yingli Lin Zhian Li Chuanjian Tu Source Type: research
2020 Annual Report of National Clinical Database-Breast Cancer Registry: 10-year mortality of elderly breast cancer patients in Japan
Breast Cancer. 2024 Jan 5. doi: 10.1007/s12282-023-01532-8. Online ahead of print.ABSTRACTThe Japanese Breast Cancer Society initiated the breast cancer registry in 1975, which transitioned to the National Clinical Database-Breast Cancer Registry in 2012. This annual report presents data from 2020 and analyzes the ten-year mortality rates for those aged 65 and older. We analyzed data from 93,784 breast cancer (BC) cases registered in 2020 and assessed 10-year mortality rates for 36,279 elderly patients diagnosed between 2008 and 2012. In 2020, 99.4% of BC cases were females with a median age of 61. Most (65%) were diagnose...
Source: Breast Cancer - January 5, 2024 Category: Cancer & Oncology Authors: Yasuaki Sagara Hiraku Kumamaru Naoki Niikura Minoru Miyashita Takaaki Konishi Takayuki Iwamoto Naoko Sanuki Kenta Tanakura Masayuki Nagahashi Naoki Hayashi Masayuki Yoshida Naoko Kinukawa Chie Watanabe Masakazu Toi Shigehira Saji Source Type: research
2020 Annual Report of National Clinical Database-Breast Cancer Registry: 10-year mortality of elderly breast cancer patients in Japan
Breast Cancer. 2024 Jan 5. doi: 10.1007/s12282-023-01532-8. Online ahead of print.ABSTRACTThe Japanese Breast Cancer Society initiated the breast cancer registry in 1975, which transitioned to the National Clinical Database-Breast Cancer Registry in 2012. This annual report presents data from 2020 and analyzes the ten-year mortality rates for those aged 65 and older. We analyzed data from 93,784 breast cancer (BC) cases registered in 2020 and assessed 10-year mortality rates for 36,279 elderly patients diagnosed between 2008 and 2012. In 2020, 99.4% of BC cases were females with a median age of 61. Most (65%) were diagnose...
Source: Breast Cancer - January 5, 2024 Category: Cancer & Oncology Authors: Yasuaki Sagara Hiraku Kumamaru Naoki Niikura Minoru Miyashita Takaaki Konishi Takayuki Iwamoto Naoko Sanuki Kenta Tanakura Masayuki Nagahashi Naoki Hayashi Masayuki Yoshida Naoko Kinukawa Chie Watanabe Masakazu Toi Shigehira Saji Source Type: research
2020 Annual Report of National Clinical Database-Breast Cancer Registry: 10-year mortality of elderly breast cancer patients in Japan
Breast Cancer. 2024 Jan 5. doi: 10.1007/s12282-023-01532-8. Online ahead of print.ABSTRACTThe Japanese Breast Cancer Society initiated the breast cancer registry in 1975, which transitioned to the National Clinical Database-Breast Cancer Registry in 2012. This annual report presents data from 2020 and analyzes the ten-year mortality rates for those aged 65 and older. We analyzed data from 93,784 breast cancer (BC) cases registered in 2020 and assessed 10-year mortality rates for 36,279 elderly patients diagnosed between 2008 and 2012. In 2020, 99.4% of BC cases were females with a median age of 61. Most (65%) were diagnose...
Source: Breast Cancer - January 5, 2024 Category: Cancer & Oncology Authors: Yasuaki Sagara Hiraku Kumamaru Naoki Niikura Minoru Miyashita Takaaki Konishi Takayuki Iwamoto Naoko Sanuki Kenta Tanakura Masayuki Nagahashi Naoki Hayashi Masayuki Yoshida Naoko Kinukawa Chie Watanabe Masakazu Toi Shigehira Saji Source Type: research
2020 Annual Report of National Clinical Database-Breast Cancer Registry: 10-year mortality of elderly breast cancer patients in Japan
Breast Cancer. 2024 Jan 5. doi: 10.1007/s12282-023-01532-8. Online ahead of print.ABSTRACTThe Japanese Breast Cancer Society initiated the breast cancer registry in 1975, which transitioned to the National Clinical Database-Breast Cancer Registry in 2012. This annual report presents data from 2020 and analyzes the ten-year mortality rates for those aged 65 and older. We analyzed data from 93,784 breast cancer (BC) cases registered in 2020 and assessed 10-year mortality rates for 36,279 elderly patients diagnosed between 2008 and 2012. In 2020, 99.4% of BC cases were females with a median age of 61. Most (65%) were diagnose...
Source: Breast Cancer - January 5, 2024 Category: Cancer & Oncology Authors: Yasuaki Sagara Hiraku Kumamaru Naoki Niikura Minoru Miyashita Takaaki Konishi Takayuki Iwamoto Naoko Sanuki Kenta Tanakura Masayuki Nagahashi Naoki Hayashi Masayuki Yoshida Naoko Kinukawa Chie Watanabe Masakazu Toi Shigehira Saji Source Type: research
Pilot trial of an electronic patient-reported outcome monitoring system in patients with metastatic breast cancer undergoing chemotherapy
CONCLUSION: Our developed ePROM system was able to capture symptoms accurately in patients with metastatic breast cancer undergoing chemotherapy while maintaining a high response compliance.PMID:38175422 | DOI:10.1007/s12282-023-01537-3 (Source: Breast Cancer)
Source: Breast Cancer - January 4, 2024 Category: Cancer & Oncology Authors: Naruto Taira Yuichiro Kikawa Takayuki Iwamoto Yuichiro Miyoshi Kyoko Hara Seiji Yoshitomi Hajime Hikino Hirotoshi Takahashi Daisuke Takabatake Shinichiro Kubo Masahiko Ikeda Hiroyoshi Doihara Tadahiko Shien Hiromi Okuyama Yuko Tanabe Fumikata Hara Kosho Y Source Type: research
Pilot trial of an electronic patient-reported outcome monitoring system in patients with metastatic breast cancer undergoing chemotherapy
CONCLUSION: Our developed ePROM system was able to capture symptoms accurately in patients with metastatic breast cancer undergoing chemotherapy while maintaining a high response compliance.PMID:38175422 | DOI:10.1007/s12282-023-01537-3 (Source: Breast Cancer)
Source: Breast Cancer - January 4, 2024 Category: Cancer & Oncology Authors: Naruto Taira Yuichiro Kikawa Takayuki Iwamoto Yuichiro Miyoshi Kyoko Hara Seiji Yoshitomi Hajime Hikino Hirotoshi Takahashi Daisuke Takabatake Shinichiro Kubo Masahiko Ikeda Hiroyoshi Doihara Tadahiko Shien Hiromi Okuyama Yuko Tanabe Fumikata Hara Kosho Y Source Type: research
The influence of chronic renal insufficiency on multi-therapeutic modalities for breast cancer: a single-center experience
CONCLUSIONS: Breast cancer patients with late-stage CKD may receive insufficient therapeutic modalities. Although the recurrence-free survival rate did not differ significantly by the status of CKD, patients with breast cancer and late-stage CKD had shorter overall survival time but a lower breast cancer-related mortality rate, indicated that the mortality was related to underlying disease.PMID:38150135 | DOI:10.1007/s12282-023-01530-w (Source: Breast Cancer)
Source: Breast Cancer - December 27, 2023 Category: Cancer & Oncology Authors: Yi-Wen Hong I-Ming Kuo Wen-Ling Kuo Chi-Chang Yu Shih-Che Shen Hsiu-Pei Tsai Chia-Hui Chu Hui-Yu Ho Yung-Feng Lo Shin-Cheh Chen Yung-Chang Lin Chih-Ying Chien Hsu-Huan Chou Source Type: research
The influence of chronic renal insufficiency on multi-therapeutic modalities for breast cancer: a single-center experience
CONCLUSIONS: Breast cancer patients with late-stage CKD may receive insufficient therapeutic modalities. Although the recurrence-free survival rate did not differ significantly by the status of CKD, patients with breast cancer and late-stage CKD had shorter overall survival time but a lower breast cancer-related mortality rate, indicated that the mortality was related to underlying disease.PMID:38150135 | DOI:10.1007/s12282-023-01530-w (Source: Breast Cancer)
Source: Breast Cancer - December 27, 2023 Category: Cancer & Oncology Authors: Yi-Wen Hong I-Ming Kuo Wen-Ling Kuo Chi-Chang Yu Shih-Che Shen Hsiu-Pei Tsai Chia-Hui Chu Hui-Yu Ho Yung-Feng Lo Shin-Cheh Chen Yung-Chang Lin Chih-Ying Chien Hsu-Huan Chou Source Type: research
