Viability of focal dose escalation to prostate cancer intraprostatic lesions using HDR prostate brachytherapy
This study aimed to determine the viability of focal dose escalation to prostate cancer intraprostatic lesions (IPLs) from multiparametric magnetic resonance (mpMRI) and prostate-specific membrane antigen positron emission tomography (PSMA-PET) images using high-dose-rate (HDR) prostate brachytherapy (pBT). (Source: Brachytherapy)
Source: Brachytherapy - September 23, 2023 Category: Cancer & Oncology Authors: Joel Poder, Samantha Radvan, Andrew Howie, Farshad Kasraei, Annaleise Parker, Joseph Bucci, Annette Haworth Source Type: research

Conformal 3D computed tomography planned endoluminal brachytherapy for the local control of esophageal cancer
To outline the toxicity, tolerability, and efficacy of a 3D conformal computed tomography planned endoluminal brachytherapy (ELBT) treatment for esophageal adenocarcinoma (OAC) or squamous cell carcinoma (OSCC). (Source: Brachytherapy)
Source: Brachytherapy - September 22, 2023 Category: Cancer & Oncology Authors: Christopher M. Jones, Annabel Lyles, Peter Bownes, Rebecca Goody, Mohan Hingorani, Eldho Joseph, Ganesh Radhakrishna Source Type: research

Comparison of intraluminal brachytherapy combined with and without stent placement for treatment of obstructive jaundice induced by tumor thrombus
To compare the safety and efficacy of intraluminal brachytherapy with iodine-125 (125I) seed strand implantation combined with and without stent placement to treat patients with obstructive jaundice induced by tumor thrombus. (Source: Brachytherapy)
Source: Brachytherapy - September 19, 2023 Category: Cancer & Oncology Authors: HuiYi Sun, MinJie Yang, FeiHang Wang, DanYang Zhao, XuDong Qu, ZhiPing Yan, FuYou Li, LingXiao Liu Source Type: research

Utilizing a novel hybrid brachytherapy technique FINITO (Freehand Interstitial Needles in addition to Tandem and Ovoid) for locally advanced cervical cancer
We aimed to assess the clinical feasibility and advantages of using a novel hybrid brachytherapy technique by placing Freehand Interstitial Needles in addition to the Tandem and Ovoid applicator (FINITO) for the treatment of locally advanced cervical cancer (LAC). (Source: Brachytherapy)
Source: Brachytherapy - September 16, 2023 Category: Cancer & Oncology Authors: Yue H. Zhang, Sara Martin, Han Liu, Dorin Todor, James J. Sohn, Bridget Quinn, Louise.E. Francis, Melinda Roach, Emma C. Fields Source Type: research

Surgically targeted radiation therapy (STaRT) for recurrent brain metastases: Initial clinical experience
This study evaluates the outcomes of recurrent brain metastasis treated with resection and brachytherapy using a novel Cesium-131 carrier, termed surgically targeted radiation therapy (STaRT), and compares them to the first course of external beam radiotherapy (EBRT). (Source: Brachytherapy)
Source: Brachytherapy - September 16, 2023 Category: Cancer & Oncology Authors: Tugce Kutuk, Ranjini Tolakanahalli, Vibha Chaswal, Sreenija Yarlagadda, Roberto Herrera, Haley Appel, Alonso La Rosa, Vivek Mishra, D.Jay J. Wieczorek, Michael W. McDermott, Vitaly Siomin, Minesh P. Mehta, Yazmin Odia, Alonso N. Gutierrez, Rupesh Kotecha Source Type: research

Clinical implementation of 3D transvaginal ultrasound for intraoperative guidance of needle implant in template interstitial gynecologic high-dose-rate brachytherapy
To demonstrate novel clinical implementation of a 3D transvaginal ultrasound (3DTVUS) system for intraoperative needle insertion guidance in perineal template interstitial gynecologic high-dose-rate brachytherapy and assess its impact on implant quality. (Source: Brachytherapy)
Source: Brachytherapy - September 16, 2023 Category: Cancer & Oncology Authors: Devin Van Elburg, Tyler Meyer, Kevin Martell, Sarah Quirk, Robyn Banerjee, Tien Phan, Aaron Fenster, Michael Roumeliotis Source Type: research

Novel intraocular shielding device for eye plaque brachytherapy using magnetite nanoparticles: A proof-of-concept study using radiochromic film and Monte Carlo simulations
Eye plaque brachytherapy is a mainstay treatment for uveal melanomas despite potential toxicities to normal tissues. This work proposes a nanoparticle ferrofluid as a novel intraocular shielding device. With a modified magnetic plaque, the shielding particles are drawn to the tumor surface, attenuating dose beyond the tumor while maintaining prescription dose to the target. (Source: Brachytherapy)
Source: Brachytherapy - September 15, 2023 Category: Cancer & Oncology Authors: Courtney C. Oare, James P. Dailey, Bruce Gerbi, Clara Ferreira Source Type: research

Reirradiation with advanced brachytherapy techniques in recurrent GYN cancers
To evaluate clinical outcomes of recurrent gynaecological cancers treated with reirradiation (reRT) using advanced brachytherapy (BT) technique. (Source: Brachytherapy)
Source: Brachytherapy - September 14, 2023 Category: Cancer & Oncology Authors: Umesh Mahantshetty, Sheetal R. Kashid, Gargee Mulye, Lavanya Gurram, Reena Engineer, Supriya Chopra, Jaya Ghosh, Seema Gulia, Sudeep Gupta, Yogesh Ghadi, Dheera A ., Satish Kohle, Sudarshan Kadam, Santosh Menon, Kedar Deodhar, Amita Maheswari, Shylasree Source Type: research

Improved safety and quality in intravascular brachytherapy: A multi-institutional study using failure modes and effects analysis
Highlight safety considerations in intravascular brachytherapy (IVBT) programs, provide relevant quality assurance (QA) and safety measures, and establish their effectiveness. (Source: Brachytherapy)
Source: Brachytherapy - September 14, 2023 Category: Cancer & Oncology Authors: Evan D.H. Gates, Kent Wallner, Jasleen Tiwana, Eric Ford, Mark Phillips, Lan Lu, Vishruta Dumane, Ren-Dih Sheu, Minsun Kim Source Type: research

Uncertainty in magnetic resonance imaging-based prostate postimplant dosimetry: Results of a 10-person human observer study, and comparisons with automatic postimplant dosimetry
Uncertainties in postimplant quality assessment (QA) for low-dose-rate prostate brachytherapy (LDRPBT) are introduced at two steps: seed localization and contouring. We quantified how interobserver variability (IoV) introduced in both steps impacts dose-volume-histogram (DVH) parameters for MRI-based LDRPBT, and compared it with automatically derived DVH parameters. (Source: Brachytherapy)
Source: Brachytherapy - September 14, 2023 Category: Cancer & Oncology Authors: Jeremiah W. Sanders, Chad Tang, Rajat J. Kudchadker, Aradhana M. Venkatesan, Henry Mok, Alexander N. Hanania, Howard D. Thames, Teresa L. Bruno, Christine Starks, Edwin Santiago, Mandy Cunningham, Steven J. Frank Source Type: research

The American Brachytherapy Society and Indian Brachytherapy Society consensus statement for the establishment of high-dose-rate brachytherapy programs for gynecological malignancies in low- and middle-income countries
The global cervical cancer burden is disproportionately high in low- and middle-income countries (LMICs), and outcomes can be governed by the accessibility of appropriate screening and treatment. High-dose-rate (HDR) brachytherapy plays a central role in cervical cancer treatment, improving local control and overall survival. The American Brachytherapy Society (ABS) and Indian Brachytherapy Society (IBS) collaborated to provide this succinct consensus statement guiding the establishment of brachytherapy programs for gynecological malignancies in resource-limited settings. (Source: Brachytherapy)
Source: Brachytherapy - September 11, 2023 Category: Cancer & Oncology Authors: Surbhi Grover, Katie E. Lichter, Anna Likhacheva, Joanne W. Jang, Matthew S. Ning, Tyler P. Robin, William Small, Rajat J. Kudchadker, Jamema Swamidas, Supriya Chopra, Bhavana Rai, Sunil Dutt Sharma, Daya N. Sharma, Thayalan Kuppusamy, Ruijie Yang, Daniel Source Type: research

Actinium-225 Targeted Agents: Where Are We Now?
α-particle targeted radionuclide therapy has shown promise for optimal cancer management, an exciting new era for brachytherapy. Alpha-emitting nuclides can have significant advantages over gamma- and beta-emitters due to their high linear energy transfer (LET). While their limited path length resu lts in more specific tumor 0kill with less damage to surrounding normal tissues, their high LET can produce substantially more lethal double strand DNA breaks per radiation track than beta particles. Over the last decade, the physical and chemical attributes of Actinium-225 (225Ac) including its hal f-life, decay schemes, path ...
Source: Brachytherapy - September 8, 2023 Category: Cancer & Oncology Authors: Firas Mourtada, Katsumi Tomiyoshi, Jennifer Sims-Mourtada, Yuki Mukai-Sasaki, Takayuki Yagihashi, Yuta Namiki, Taro Murai, David J. Yang, Tomio Inoue Tags: Invited Perspectives and Reviews Source Type: research

Virtual reality technology: A potential tool to enhance brachytherapy training and delivery
Virtual reality (VR), a virtual environment that is designed to be perceived as reality, has been around for many decades but recent improvements in computer processing power, battery capacity, and cost have made it more accessible and available. Current systems allow for a user to wear a headset that replaces the field of vision in both eyes with stereoscopic screens, generating imagery that the brain interprets in three dimensions and allowing the user to be immersed in an entirely virtual environment. (Source: Brachytherapy)
Source: Brachytherapy - September 5, 2023 Category: Cancer & Oncology Authors: Arpan V. Prabhu, Melissa Peterman, Anam Kesaria, Santanu Samanta, Richard Crownover, Gary D. Lewis Source Type: research

Thursday, June 22, 2023 8:20 AM - 9:20 AM PP01 Presentation Time: 8:20 AM
This study examines more recent trends in brachytherapy utilization from 2004 to 2020 to assess whether trends have begun to reverse after awareness increased into the importance of brachytherapy. (Source: Brachytherapy)
Source: Brachytherapy - September 1, 2023 Category: Cancer & Oncology Authors: Darien N. Colson-Fearon, Akila Viswanathan Tags: Scientific Session: GYN Proffered Papers I Source Type: research

PP02   Presentation Time: 8:29 AM
Cervical cancer is the most common cancer treated at Gaborone Private Hospital (GPH), the only facility offering radiotherapy services in Botswana. For curative intent, patients receive concurrent chemoradiation followed by brachytherapy boost. Brachytherapy services commenced in Botswana in 2012, and treatment began by using traditional A points for planning. A successful brachytherapy project was established with mentorship by clinicians from Massachusetts General Hospital and the University of Pennsylvania. (Source: Brachytherapy)
Source: Brachytherapy - September 1, 2023 Category: Cancer & Oncology Authors: Memory Fadziso Bvochora-Nsingo, Elliphine Gwangwavs, Rohini Bhatia, Thabiso Itshabeng, Masud Rana Khan Source Type: research