Uncertainty in magnetic resonance imaging-based prostate postimplant dosimetry: Results of a 10-person human observer study, and comparisons with automatic postimplant dosimetry

Uncertainties in postimplant quality assessment (QA) for low-dose-rate prostate brachytherapy (LDRPBT) are introduced at two steps: seed localization and contouring. We quantified how interobserver variability (IoV) introduced in both steps impacts dose-volume-histogram (DVH) parameters for MRI-based LDRPBT, and compared it with automatically derived DVH parameters.

Source: Brachytherapy - September 14, 2023 Category: Cancer & Oncology Authors: Jeremiah W. Sanders, Chad Tang, Rajat J. Kudchadker, Aradhana M. Venkatesan, Henry Mok, Alexander N. Hanania, Howard D. Thames, Teresa L. Bruno, Christine Starks, Edwin Santiago, Mandy Cunningham, Steven J. Frank Source Type: research