Table of Contents
(Source: Brachytherapy)
Source: Brachytherapy - January 1, 2024 Category: Cancer & Oncology Source Type: research

Advanced navigation technology enables endobronchial brachytherapy for peripheral lung cancer: An old technique plays a new role
To investigate the feasibility of super-selectively endobronchial brachytherapy in the treatment of peripheral lung cancer guided by advanced navigation technology. (Source: Brachytherapy)
Source: Brachytherapy - December 30, 2023 Category: Cancer & Oncology Authors: Yishi Li, Juan Jiang, Qingfeng Jiang, Wenli Lu, Haixia Cui, Yanbo Song, Wencong Li, Tao Zhang, Longhao Li Tags: Original Article Source Type: research

Safety of high-dose rate (HDR) brachytherapy for patients with prostate cancer and history of prior chemoradiation for rectal cancer: A case series
A history of prior pelvic radiation therapy (RT) for rectal cancer is a relative contraindication for definitive RT for prostate cancer. High-dose-rate (HDR) brachytherapy can significantly limit the dose to surrounding tissues compared to external beam RT. However, there is limited data surrounding its safety in patients with prior pelvic RT. (Source: Brachytherapy)
Source: Brachytherapy - December 29, 2023 Category: Cancer & Oncology Authors: Horatio Thomas, Jie Jane Chen, Hasan Abdul-Baki, Ali Sabbagh, Haitham Shaheen, Oi Wai Chau, Nauman Malik, Alan Ayoub, Comron Hassanzadeh, I-Chow Hsu, Osama Mohamad Tags: Original Article Source Type: research

Development and clinical implementation of simple needle attachment post placement interstitial template (SNAPP-IT) enabling a shorter, more direct needle path while preserving tumor visualization
Historical gynecologic interstitial brachytherapy templates block direct tumor visualization during needle placement, presenting an opportunity for clinical innovation to develop a novel interstitial template allowing direct tumor visualization during needle insertion. (Source: Brachytherapy)
Source: Brachytherapy - December 29, 2023 Category: Cancer & Oncology Authors: Claire C. Baniel, Caressa Hui, Pete A. Franco, Thomas Niedermayr, Elizabeth A. Kidd Tags: Original Article Source Type: research

Real-time definition of single seed placement sensitivity in low-dose-rate prostate brachytherapy
PURPOSE: In low-dose-rate brachytherapy, iodine-125 seeds are implanted based on a treatment plan, generated with respect to different dose constraints. The quality of the dose distribution depends on a precise seed placement, however, during treatment planning the impact on the dose parameters when certain seeds fail to be placed precisely is not clear. METHODS AND MATERIALS: We developed a method using automatic differentiation to calculate gradients of dose parameters with regard to the seeds ’ positions. (Source: Brachytherapy)
Source: Brachytherapy - December 23, 2023 Category: Cancer & Oncology Authors: Katharina I. Jerg, Ernest Chukwudi N. Okonkwo, Frank A. Giordano, Yasser Abo-Madyan, Felix Momm, J ürgen W. Hesser Tags: Original Article Source Type: research

Exploratory analysis of the cervix tumoral HPV antigen-specific T-cell repertoire during chemoradiation and after brachytherapy
Chemoradiation (CRT) may modulate the immune milieu as an in-situ vaccine. Rapid dose delivery of brachytherapy has unclear impact on T-cell repertoires. HPV-associated cancers express viral oncoproteins E6/E7, which enable tracking antigen/tumor-specific immunity during CRT. (Source: Brachytherapy)
Source: Brachytherapy - December 20, 2023 Category: Cancer & Oncology Authors: Gohar S. Manzar, Molly B. El Alam, Erica J. Lynn, Tatiana V. Karpinets, Timothy Harris, David Lo, Kyoko Yoshida-Court, Tatiana Cisneros Napravnik, Julie Sammouri, Daniel Lin, Lauren M. Andring, Julianna Bronk, Xiaogang Wu, Travis T. Sims, Geena Mathew, Ka Tags: Original Article Source Type: research

Redefining the role of pulsed-dose-rate brachytherapy in cervical cancer treatment using a preplanned approach
This study aims to determine predictive factors for cervical cancer patients who would benefit more from high-dose-rate (HDR) or pulsed-dose-rate (PDR) brachytherapy. (Source: Brachytherapy)
Source: Brachytherapy - December 17, 2023 Category: Cancer & Oncology Authors: Pierre Annede, Charlotte Robert, Sophie Espenel, Isabelle Dumas, Cyrus Chargari Tags: Original Article Source Type: research

A study on short-term efficacy and safety of Iodine-125 brachytherapy coupled with preoperative arterial chemoembolization for hypervascular spinal metastasis
This study aimed to observe the short-term efficacy and safety of Iodine-125 brachytherapy (125I BT) combined with preoperative transcatheter arterial chemoembolization (TACE) for hypervascular spinal metastasis. (Source: Brachytherapy)
Source: Brachytherapy - December 2, 2023 Category: Cancer & Oncology Authors: Menglong Zhang, Menglin Zhang, Miaoshen Yu, Yusheng Song, Yan Wang Source Type: research

Gynecological technical notes for appropriate spacer injections
Despite its efficacy, if adherence to dose constraints for surrounding normal tissues proves unattainable, the risk of late radiation-related adverse events after primary radiotherapy involving brachytherapy remains a noteworthy concern. Some studies suggest that similar to prostate radiotherapy, spacers may potentially reduce doses to surrounding healthy rectal or bladder tissues. However, guidance on spacer injections for gynecologic brachytherapy is scarce, and the optimal anatomical location for spacer placement remains undefined. (Source: Brachytherapy)
Source: Brachytherapy - November 30, 2023 Category: Cancer & Oncology Authors: Mariko Nakahara, Naoya Murakami, Takahito Chiba, Ayaka Nagao, Kae Okuma, Tairo Kashihara, Tomoya Kaneda, Kana Takahashi, Koji Inaba, Yuko Nakayama, Tomoyasu Kato, Hiroshi Igaki Tags: Technical Note Source Type: research

Safe dose escalation and reduction of the fraction number of uterine cervical brachytherapy using a gel spacer in the rectovaginal and vesicouterine septum: A planning study
To evaluate the possibility of dose escalation and reduction of fraction number in cervical brachytherapy using a gel spacer. (Source: Brachytherapy)
Source: Brachytherapy - November 30, 2023 Category: Cancer & Oncology Authors: Jun Takatsu, Naoya Murakami, Yoichi Muramoto, Tatsuki Karino, Masaki Oshima, Yasuo Kosugi, Terufumi Kawamoto, Yasuhisa Terao, Naoto Shikama Tags: Original Article Source Type: research

Heterogeneous physical phantom for I-125 dose measurements and dose-to-medium determination
In this paper we present a further step in the implementation of a physical phantom designed to generate sets of “true” independent reference data as requested by TG-186, intending to address and mitigate the scarcity of experimental studies on brachytherapy (BT) validation in heterogeneous media. To achieve this, we incorporated well-known heterogeneous materials into the phantom in order to perform measu rements of 125I dose distribution. The work aims to experimentally validate Monte Carlo (MC) calculations based on MBDCA and determine the conversion factors from LiF response to absorbed dose in different media, usi...
Source: Brachytherapy - November 27, 2023 Category: Cancer & Oncology Authors: Paula Cristina Guimar ães Antunes, Paulo de Tarso Dalledone Siqueira, Julian Marco Barbosa Shorto, Hélio Yoriyaz Source Type: research

Toward a deep learning-based magnetic resonance imaging only workflow for postimplant dosimetry in I-125 seed brachytherapy for prostate cancer
The current standard imaging-technique for creating postplans in seed prostate brachytherapy is computed tomography (CT), that is associated with additional radiation exposure and poor soft tissue contrast. To establish a magnetic resonance imaging (MRI) only workflow combining improved tissue contrast and high seed detectability, a deep learning-approach for automatic seed segmentation on MRI-scans was developed. (Source: Brachytherapy)
Source: Brachytherapy - November 25, 2023 Category: Cancer & Oncology Authors: Johanna Grigo, Andre Karius, Jannis Hanspach, Lion M ücke, Frederik B. Laun, Yixing Huang, Vratislav Strnad, Rainer Fietkau, Christoph Bert, Florian Putz Tags: Original Article Source Type: research

Dosimetric comparison of stereotactic MR-guided radiation therapy (SMART) and HDR brachytherapy boost in cervical cancer
The standard of care in locally advanced cervical cancer (LACC) is concomitant chemoradiotherapy followed by high-dose-rate brachytherapy (HDR-BT). Although previous studies compared HDR-BT with stereotactic body radiotherapy (SBRT), there is scarce data regarding the dosimetric outcomes of stereotactic MR-guided adaptive radiation therapy (SMART) boost in lieu of HDR-BT. (Source: Brachytherapy)
Source: Brachytherapy - November 23, 2023 Category: Cancer & Oncology Authors: Neris Dincer, Gamze Ugurluer, Teuta Zoto Mustafayev, Anatolia Serkizyan, Gokhan Aydin, G örkem Güngör, Bulent Yapici, Banu Atalar, Enis Özyar Source Type: research

A postimplant dosimetry simulation framework for robustness evaluation in permanent breast seed implant brachytherapy
Permanent breast seed implant (PBSI) brachytherapy is a promising treatment that has the potential to be widely utilized with increased standardization, optimization, and robustness. Excellent early efficacy and very high patient acceptance were reported, however, to further evaluate and improve planning strategies, a framework to quantify plan robustness to implant uncertainties is necessary. (Source: Brachytherapy)
Source: Brachytherapy - November 8, 2023 Category: Cancer & Oncology Authors: Claire Zhang, Jeffrey L. Andrews, Deidre Batchelar, Juanita Crook, Michelle Hilts Source Type: research

Editorial Board
(Source: Brachytherapy)
Source: Brachytherapy - November 1, 2023 Category: Cancer & Oncology Source Type: research