Correction to: efficacy and safety of the switch of Triumeq ® to generic (abacavir + lamivudine) + Tivicay®: data at 24 weeks
BMC Pharmacol Toxicol. 2023 Oct 6;24(1):49. doi: 10.1186/s40360-023-00693-8.NO ABSTRACTPMID:37803423 | PMC:PMC10557315 | DOI:10.1186/s40360-023-00693-8 (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - October 6, 2023 Category: Drugs & Pharmacology Authors: Juli án Olalla Javier P érez-Stachowski Bego ña Tortajada Alfonso Del Arco Efr én Márquez Javier De la Torre Miriam Nieto Jos é María García de Lomas Jos é Luis Prada Javier Garc ía-Alegría Source Type: research
Correction to: efficacy and safety of the switch of Triumeq ® to generic (abacavir + lamivudine) + Tivicay®: data at 24 weeks
BMC Pharmacol Toxicol. 2023 Oct 6;24(1):49. doi: 10.1186/s40360-023-00693-8.NO ABSTRACTPMID:37803423 | DOI:10.1186/s40360-023-00693-8 (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - October 6, 2023 Category: Drugs & Pharmacology Authors: Juli án Olalla Javier P érez-Stachowski Bego ña Tortajada Alfonso Del Arco Efr én Márquez Javier De la Torre Miriam Nieto Jos é María García de Lomas Jos é Luis Prada Javier Garc ía-Alegría Source Type: research
Butyrate alleviates renal inflammation and fibrosis in a rat model of polycystic ovarian syndrome by suppression of SDF-1
CONCLUSION: The present investigation demonstrates that PCOS declines renal function, which is accompanied by renal inflammation, apoptosis and fibrosis. The study further suggests that butyrate, an HDAC2i restores renal function by suppressing renal SDF-1 with subsequent attenuation of renal inflammation, apoptosis and fibrosis.PMID:37789355 | PMC:PMC10548736 | DOI:10.1186/s40360-023-00692-9 (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - October 3, 2023 Category: Drugs & Pharmacology Authors: Al-Amin M Bashir Kehinde S Olaniyi Source Type: research
Butyrate alleviates renal inflammation and fibrosis in a rat model of polycystic ovarian syndrome by suppression of SDF-1
CONCLUSION: The present investigation demonstrates that PCOS declines renal function, which is accompanied by renal inflammation, apoptosis and fibrosis. The study further suggests that butyrate, an HDAC2i restores renal function by suppressing renal SDF-1 with subsequent attenuation of renal inflammation, apoptosis and fibrosis.PMID:37789355 | DOI:10.1186/s40360-023-00692-9 (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - October 3, 2023 Category: Drugs & Pharmacology Authors: Al-Amin M Bashir Kehinde S Olaniyi Source Type: research
Population pharmacokinetic analysis of lopinavir in HIV negative individuals exposed to SARS-CoV-2: a COPEP (COronavirus Post-Exposure Prophylaxis) sub-study
CONCLUSION: Our analysis indicated that LPV circulating concentrations were similar between COPEP participants and PLWH, and that published popPK models described our data in a comparable way.PMID:37759315 | PMC:PMC10536696 | DOI:10.1186/s40360-023-00687-6 (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - September 27, 2023 Category: Drugs & Pharmacology Authors: Paul Thoueille Margot Delfraysse Pascal Andre Thierry Buclin Laurent A Decosterd Chiara Fedeli Pilar Ustero Alexandra Calmy Monia Guidi Swiss HIV Cohort Study Source Type: research
Population pharmacokinetic analysis of lopinavir in HIV negative individuals exposed to SARS-CoV-2: a COPEP (COronavirus Post-Exposure Prophylaxis) sub-study
CONCLUSION: Our analysis indicated that LPV circulating concentrations were similar between COPEP participants and PLWH, and that published popPK models described our data in a comparable way.PMID:37759315 | DOI:10.1186/s40360-023-00687-6 (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - September 27, 2023 Category: Drugs & Pharmacology Authors: Paul Thoueille Margot Delfraysse Pascal Andre Thierry Buclin Laurent A Decosterd Chiara Fedeli Pilar Ustero Alexandra Calmy Monia Guidi Swiss HIV Cohort Study Source Type: research
Panobinostat (LBH589) combined with AM1241 induces cervical cancer cell apoptosis through autophagy pathway
CONCLUSION: LBH589 combined with AM1241 activated the endoplasmic reticulum emergency pathway, DNA damage repair signaling pathway, oxidative stress and autophagy pathway, ultimately promoting the apoptosis of cervical cancer cells. These findings suggest that the co-administration of LBH589 and AM1241 may be a new treatment plan for the treatment of cervical cancer.PMID:37740231 | PMC:PMC10517494 | DOI:10.1186/s40360-023-00686-7 (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - September 22, 2023 Category: Drugs & Pharmacology Authors: Bo Sheng Wenwen Wang Dongyue Xia Xiangdong Qu Source Type: research
Bilirubin potentiates etomidate-induced sedation by enhancing GABA-induced currents after bile duct ligation
CONCLUSIONS: Our results demonstrated that pathologic bilirubin in CSF could enhance etomidate induced sedation. The mechanism may be that bilirubin increase the GABA-induced currents of rat pyramidal neurons.PMID:37740245 | PMC:PMC10517516 | DOI:10.1186/s40360-023-00675-w (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - September 22, 2023 Category: Drugs & Pharmacology Authors: Hao Gao Qian Zhao Jian-Gang Song Guo-Xia Hu Wei-Feng Yu Ying-Fu Jiao Jin-Chao Song Source Type: research
