Facing frailty: Are you ready?
Biosci Trends. 2023 Aug 23. doi: 10.5582/bst.2023.01191. Online ahead of print.ABSTRACTBy far, there is no general consensus concerning the definition of frailty even though it may be a global public health concern with aging of the population. It is regarded as a pathophysiological state before development of a severe illness that is associated with many adverse outcomes. Although previous studies attempted to verify its clinical value to prevent the development of serious illness, robust evidence is lacking. Based on previous studies of frailty, the current study analyzed the problems with existing investigations of frai...
Source: BioScience Trends - August 23, 2023 Category: Biomedical Science Authors: Tetsuya Asakawa Takashi Karako Source Type: research
Geriatric syndromes, chronic inflammation, and advances in the management of frailty: A review with new insights
Biosci Trends. 2023 Aug 23. doi: 10.5582/bst.2023.01184. Online ahead of print.ABSTRACTAs people age, geriatric syndromes characterized by frailty significantly impact both clinical practice and public health. Aging weakens people's immune functions, leading to chronic low-grade inflammation that ultimately contributes to the development of frailty. Effectively managing geriatric syndromes and frailty can help alleviate the economic burden of an aging population. This review delves into the intricate relationship among aging, infection-induced inflammation, chronic inflammation, and frailty. In addition, it analyzes variou...
Source: BioScience Trends - August 23, 2023 Category: Biomedical Science Authors: Niuniu Li Gaolin Liu Hong Gao Qiang Wu Juan Meng Fei Wang Siwei Jiang Meixia Chen Wenhui Xu Yifan Zhang Yanjun Wang Yingqian Feng Juncai Liu Cheng Xu Hongzhou Lu Source Type: research
The framework for modern community medicine in Japan
Biosci Trends. 2023 Aug 24. doi: 10.5582/bst.2023.01199. Online ahead of print.ABSTRACTAlong with the transition to depopulation and an aging society in Japan, the modification of community medicine and its related systems is required. With this in mind, the Japanese government has recently advocated two major plans: 'Community Healthcare Vision' and 'Community-based Integrated Care System'. This paper proposes a theoretical framework to understand modern community medicine based on the ongoing government plans. The key viewpoints consisting of the framework are 'community and/or region', 'care systematization,' and 'cowor...
Source: BioScience Trends - August 23, 2023 Category: Biomedical Science Authors: Kazuhiko Kotani Source Type: research
Surgical indications for solid hepatic benign tumors: An updated literature review
This article examines recent literature and it discusses the surgical indications for hepatic hemangioma, focal nodular hyperplasia, and hepatic adenoma while summarizing modifications in clinical management.PMID:37599079 | DOI:10.5582/bst.2023.01152 (Source: BioScience Trends)
Source: BioScience Trends - August 20, 2023 Category: Biomedical Science Authors: Zhihong Zhang Jun Ji Guoteng Qiu Ziqi Hou Shizheng Mi Zhaoxing Jin Yunlong Dai Qingyun Xie Yong Zeng Jiwei Huang Source Type: research
Association between sarcopenia with incident cardio-cerebrovascular disease: A systematic review and meta-analysis
In conclusion, sarcopenia and sarcopenic obesity are significantly associated with an elevated risk of developing CCVD. However, further prospective cohort studies are warranted to validate this relationship while controlling for confounding factors.PMID:37574268 | DOI:10.5582/bst.2023.01130 (Source: BioScience Trends)
Source: BioScience Trends - August 13, 2023 Category: Biomedical Science Authors: Miao Fang Chunhua Liu Yuan Liu Guo Tang Chunling Li Lei Guo Source Type: research
An expanded view of infertility: The challenge of the changing profiling of major birth defects in China
Biosci Trends. 2023 Jul 20. doi: 10.5582/bst.2023.01160. Online ahead of print.ABSTRACTOver the past two decades, China has experienced a significant decline in birth rates, accompanied by a decrease in fertility and changes in major congenital defects. The development of assisted reproductive technology (ART) has brought hope to individuals facing infertility. However, some issues related to reproductive health and congenital defects have arisen. The reasons for the changing profiling of birth defects and the relationship between the decline in fertility and ART need to be further investigated. Lifestyle factors such as n...
Source: BioScience Trends - July 19, 2023 Category: Biomedical Science Authors: Zhongzhong Chen Yanlin Wang Fuying Lan Shen Li Jianhua Wang Source Type: research
