Considering traditional Chinese medicine as adjunct therapy in the management of chronic constipation by regulating intestinal flora
Biosci Trends. 2024 Mar 25. doi: 10.5582/bst.2024.01036. Online ahead of print.ABSTRACTChronic constipation is one of the most common gastrointestinal disorders worldwide. Due to changes in diet, lifestyle, and the aging population, the incidence of chronic constipation has increased year by year. It has had an impact on daily life and poses a considerable economic burden. Nowadays, many patients with chronic constipation try to seek help from complementary and alternative therapies, and traditional Chinese medicine (TCM) is often their choice. The intestinal flora play an important role in the pathogenesis of constipation...
Source: BioScience Trends - March 24, 2024 Category: Biomedical Science Authors: Ke Wang Hua Qiu Fang Chen Pingping Cai Fanghua Qi Source Type: research

Automated machine learning-based model for the prediction of pedicle screw loosening after degenerative lumbar fusion surgery
This study aimed to use machine learning algorithms to identify critical variables and predict pedicle screw loosening after degenerative lumbar fusion surgery. A total of 552 patients who underwent primary transpedicular lumbar fixation for lumbar degenerative disease were included. The LASSO method identified key features associated with pedicle screw loosening. Patient clinical characteristics, intraoperative variables, and radiographic parameters were collected and used to construct eight machine learning models, including a training set (80% of participants) and a test set (20% of participants). The XGBoost model exhi...
Source: BioScience Trends - February 28, 2024 Category: Biomedical Science Authors: Feng Jiang Xinxin Li Lei Liu Zhiyang Xie Xiaotao Wu Yuntao Wang Source Type: research