Pal power: Demonstration of the functional association of the Helicobacter pylori flagellar motor with peptidoglycan-associated lipoprotein (Pal) and its preliminary crystallographic analysis
This study is an important step towards elucidation of the non-canonical role of H. pylori Pal in the regulation, or function of, the flagellar motor.PMID:38072447 | DOI:10.5582/bst.2023.01278 (Source: BioScience Trends)
Source: BioScience Trends - December 10, 2023 Category: Biomedical Science Authors: Xiaotian Zhou Mohammad M Rahman Sharmin Q Bonny Yue Xin Nikki Liddelow Mohammad F Khan Alexandra Tikhomirova Jihane Homman-Ludiye Anna Roujeinikova Source Type: research
The immune response of hepatocellular carcinoma after locoregional and systemic therapies: The available combination option for immunotherapy
Biosci Trends. 2023 Nov 19. doi: 10.5582/bst.2023.01275. Online ahead of print.ABSTRACTHepatocellular carcinoma (HCC) is associated with a highly heterogeneous immune environment that produces an immune response to various locoregional treatments (LRTs), which in turn affects the effectiveness of immunotherapy. Although LRTs still dominate HCC therapies, 50-60% of patients will ultimately be treated with systemic therapies and might receive those treatments for the rest of their life. TACE, SIRT, and thermal ablation can dramatically increase the immunosuppressive state of HCC, a condition that can be addressed by combinat...
Source: BioScience Trends - November 19, 2023 Category: Biomedical Science Authors: Yuxin Duan Hua Zhang Tao Tan Wentao Ye Kunli Yin Yanxi Yu Meiqing Kang Jian Yang Rui Liao Source Type: research
