Differences in learning rates for item and associative memories between amnestic mild cognitive impairment and healthy controls
Conclusions: Due to more deficits in learning rate of associative memory than that of item memory, the discriminative power for aMCI tended to be larger in associative memory than in item memory when the number of learning-test trials increased. It is suggested that associative memory tests with multiple trials may be particularly useful for early detection of aMCI. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - July 25, 2013 Category: Neurology Authors: Pengyun WangJuan LiHuijie LiShouzi Zhang Source Type: research

Individual differences in solving arithmetic word problems
Conclusions: Our results indicate that cognitive styles or preferences play an important role in understanding brain activation. Our results confirm, that strong visualizers use mental imagery more strongly than weak visualizers during calculation. Moreover, our results suggest that the left AG shows a specific affinity to the verbal domain and subserves number processing in a modality-specific way. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - July 24, 2013 Category: Neurology Authors: Sabrina ZarnhoferVerena BraunsteinFranz EbnerKarl KoschutnigChrista NeuperManuel NinausGernot ReishoferAnja Ischebeck Source Type: research

Effects of ziprasidone and olanzapine on body composition and metabolic parameters: an open-label comparative pilot study
Conclusions: Ziprasidone was associated with a lower propensity for weight gain and central fat deposition than olanzapine. Studies in larger patient samples are required to confirm these results. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - July 19, 2013 Category: Neurology Authors: Subin ParkKi YiMin-Seon KimJin Hong Source Type: research

Individual differences in non-symbolic numerical abilities predict mathematical achievements but contradict ATOM
Conclusions: Our study supports the idea that mathematical abilities rely on rudimentary numerical skills that predate verbal language. By contrast, the lack of correlation among non-symbolic estimations of time, space, and number is incompatible with the idea that these magnitudes are entirely processed by the same cognitive system. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - July 1, 2013 Category: Neurology Authors: Christian AgrilloLaura PifferAndrea Adriano Source Type: research

Long-term ¿-3 fatty acid supplementation induces anti-stress effects and improves learning in rats
Chronic stress leads to secretion of the adrenal steroid hormone corticosterone, inducing hippocampal atrophy and dendritic hypertrophy in the rat amygdala. Both alterations have been correlated with memory impairment and increased anxiety. Supplementation with ω-3 fatty acids improves memory and learning in rats. The aim of this study was to evaluate the effects of ω-3 supplementation on learning and major biological and behavioral stress markers. Male Sprague–Dawley rats were randomly assigned to three experimental groups: 1) Control, 2) Vehicle, animals supplemented with water, and 3) ω-3, rats supplemented with ω...
Source: Behavioral and Brain Functions - June 14, 2013 Category: Neurology Authors: Miguel PérezGonzalo TerrerosAlexies Dagnino-Subiabre Source Type: research

Long-term omega-3 fatty acid supplementation induces anti-stress effects and improves learning in rats
Chronic stress leads to secretion of the adrenal steroid hormone corticosterone, inducing hippocampal atrophy and dendritic hypertrophy in the rat amygdala. Both alterations have been correlated with memory impairment and increased anxiety. Supplementation with omega-3 fatty acids improves memory and learning in rats. The aim of this study was to evaluate the effects of omega-3 supplementation on learning and major biological and behavioral stress markers. Male Sprague--Dawley rats were randomly assigned to three experimental groups: 1) Control, 2) Vehicle, animals supplemented with water, and 3) omega-3, rats supplemented...
Source: Behavioral and Brain Functions - June 14, 2013 Category: Neurology Authors: Miguel PérezGonzalo TerrerosAlexies Dagnino-Subiabre Source Type: research

Fatigue sensation induced by the sounds associated with mental fatigue and its related neural activities: revealed by magnetoencephalography
Conclusions: We demonstrated that the metronome sounds can cause mental fatigue sensation as a result of repeated pairings of the sounds with mental fatigue and that the insular cortex is involved in the neural substrates of this phenomenon. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - June 13, 2013 Category: Neurology Authors: Akira IshiiMasaaki TanakaMasayoshi IwamaeChongsoo KimEmi YamanoYasuyoshi Watanabe Source Type: research

Alleviation of chronic neuropathic pain by environmental enrichment in mice well after the establishment of chronic pain
Conclusions: These results suggest that environmental factors could play an important role in the rehabilitation of chronic pain patients well after the establishment of chronic pain. Enrichment is a potentially inexpensive, safe and easily implemented non-pharmacological intervention for the treatment of chronic pain. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - June 7, 2013 Category: Neurology Authors: Pascal VachonMagali MillecampsLucie LowScott ThompsosnFloriane PailleuxFrancis BeaudryCatherine BushnellLaura Stone Source Type: research

Effects of painful stimulation and acupuncture on attention networks in healthy subjects
In conclusion, (1) painful stimulation can selectively impact attention; (2) acupuncture can also selectively impact attention; i.e., both have selective influences on the alerting and executive control networks, but not on the orienting network; (3) the effects of acupuncture and painful stimulation are not identical. The mechanisms by which painful stimulation and acupuncture influence attention warrant further research. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - June 7, 2013 Category: Neurology Authors: Gang LiuHui-juan MaPan-pan HuYang-hua TianShen HuJin FanKai Wang Source Type: research

Behavioral phenotype in five individuals with de novo mutations within the GRIN2B gene
Conclusion: Our observations provide an initial delineation of the behavioral phenotype of GRIN2B mutation carriers. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - May 29, 2013 Category: Neurology Authors: Inga FreunschtBernt PoppRainer BlankSabine EndeleUte MoogHolger PetriEva-Christina ProttAndre ReisJochen RüboBernhard ZabelMartin ZenkerJohannes HebebrandDagmar Wieczorek Source Type: research

Reduced brain activation during imitation and observation of others in children with pervasive developmental disorder: a pilot study
Conclusions: Dysfunction in the MNS in children with PDD was suggested by the reduced activation in key MNS regions during tasks involving observations and imitations of others. These preliminary results suggest that further studies are needed to verify MNS dysfunction in children with PDD. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - May 29, 2013 Category: Neurology Authors: Aiko KajiumeShiori Aoyama-SetoyamaYuri Saito-HoriNobutsune IshikawaMasao Kobayashi Source Type: research

P268S in NOD2 associates with susceptibility to Parkinson¿s disease in Chinese population
Conclusions: Our results suggested that the P268S variant in NOD2 might be a risk factor for susceptibility to sporadic Parkinson’s disease in Chinese populations. It also implied that the inflammatory response may play a role in PD. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - May 7, 2013 Category: Neurology Authors: Qilin MaXingkai AnZhiming LiHuanjing ZhangWenqing HuangLiangliang CaiPeng HuQing LinChi-Meng Tzeng Source Type: research

P268S in NOD2 associates with susceptibility to Parkinson's disease in Chinese population
Conclusions: Our results suggested that the P268S variant in NOD2 might be a risk factor for susceptibility to sporadic Parkinson's disease in Chinese populations. It also implied that the inflammatory response may play a role in PD. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - May 7, 2013 Category: Neurology Authors: Qilin MaXingkai AnZhiming LiHuanjing ZhangWenqing HuangLiangliang CaiPeng HuQing LinChi-Meng Tzeng Source Type: research

Baclofen into the lateral parabrachial nucleus induces hypertonic sodium chloride intake during cell dehydration
Conclusions: Thus, injection of baclofen into the LPBN in cell-dehydrated rats induced ingestion of 0.3 M NaCl and inhibition of water intake, suggesting that even in a hyperosmotic situation, the blockade of LPBN inhibitory mechanisms with baclofen is enough to drive rats to drink hypertonic NaCl, an effect independent of changes in blood pressure. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - May 3, 2013 Category: Neurology Authors: Everton KimuraLisandra De OliveiraJosé MenaniJoão Callera Source Type: research

Motor regulation problems and pain in adults diagnosed with ADHD
Conclusions: These findings suggest that similar to children with ADHD, adults diagnosed with ADHD also have motor inhibition problems and heightened muscle tone. The presence of significantly higher pain levels and more widespread pain in the ADHD group compared to non-ADHD controls might indicate that pain is a long-term secondary effect of heightened muscle tone and restricted movement that can be demonstrated in children and adults by the MFNU battery. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - May 3, 2013 Category: Neurology Authors: Liv StrayØistein KristensenMartha LomelandMette SkorstadTorstein StrayFinn Tønnessen Source Type: research