Comparison of alterations in cerebral hemoglobin oxygenation in late life depression and Alzheimer¿s disease as assessed by near-infrared spectroscopy
Conclusions:
NIRS can detect differences in brain activation between patients with late life depression and those with AD. NIRS is a promising tool for the differential diagnosis of late life depression and AD. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - March 17, 2014 Category: Neurology Authors: Hisashi KitoAkiko RyokawaYoshihiro KinoshitaDaimei SasayamaNobuhiro SugiyamaTomomi OgiharaTakehiko YasakiTetsuya HagiwaraShin InuzukaTohru TakahashiHirokazu GennoHiroshi NoseTokiji HaniharaShinsuke WashizukaNaoji Amano Source Type: research
Comparison of alterations in cerebral hemoglobin oxygenation in late life depression and Alzheimer's disease as assessed by near-infrared spectroscopy
Conclusions:
NIRS can detect differences in brain activation between patients with late life depression and those with AD. NIRS is a promising tool for the differential diagnosis of late life depression and AD. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - March 17, 2014 Category: Neurology Authors: Hisashi KitoAkiko RyokawaYoshihiro KinoshitaDaimei SasayamaNobuhiro SugiyamaTomomi OgiharaTakehiko YasakiTetsuya HagiwaraShin InuzukaTohru TakahashiHirokazu GennoHiroshi NoseTokiji HaniharaShinsuke WashizukaNaoji Amano Source Type: research
Preliminary evidence for altered motion tracking-based hyperactivity in ADHD siblings
Conclusion:
Hyperactivity assessed by a motion tracking system may be a useful intermediate phenotype in ADHD. Prospective research should use larger samples to further examine the QbTest factors, especially the motion tracking-based Hyperactivity factor which may be a candidate for an intermediate phenotype in ADHD. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - March 13, 2014 Category: Neurology Authors: Verena RehMartin SchmidtWinfried RiefHanna Christiansen Source Type: research
Hippocampal neuronal metal ion imbalance related oxidative stress in a rat model of chronic aluminum exposure and neuroprotection of meloxicam
Neurodegenerative diseases remain a significant unresolved societal burden afflicting millions of people worldwide. Neurons in the brain are highly sensitive to oxidative stress, which can be indued by metal toxicity. In this paper, a chronic aluminum overload-induced model of neurodegeneration was used to investigate whether metal ions (Al, Fe, Mn, Cu and Zn)-related oxidative stress was involved in neurodegenerative mechanism and to identify the protective action of meloxicam against rat hippocampal neuronal injury. The metal ion contents, activity of superoxide dismutase (SOD), and content of malondialdehyde (MDA) were ...
Source: Behavioral and Brain Functions - March 11, 2014 Category: Neurology Authors: Lijuan YuRong JiangQiang SuHuarong YuJunqing Yang Source Type: research
Why the processing of repeated targets are better than that of no repetition: evidence from easy-to-difficult and difficult-to-easy switching situations
Conclusions:
The present study suggests that the feature that response time in switching trials are longer than that in repeating trials are caused by the extra endeavors engaged in the switching processes. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - February 13, 2014 Category: Neurology Authors: Guangheng DongHongli ZhouXiao LinYanbo HuQilin Lu Source Type: research
IB4(+) and TRPV1(+) sensory neurons mediate pain but not proliferation in a mouse model of squamous cell carcinoma
Conclusions:
We show in a mouse model that IB4(+) neurons play an important role in cancer-induced mechanical allodynia, while TRPV1 mediates cancer-induced thermal hyperalgesia. Characterization of the sensory fiber subtypes responsible for cancer pain could lead to the development of targeted therapeutics. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - February 13, 2014 Category: Neurology Authors: Yi YeSam BaeChi VietScott TroobDaniel BernabéBrian Schmidt Source Type: research
Association between Common Genetic Variants in the Opioid Pathway and Smoking Behaviors in Chinese Men
Conclusions:
The present study indicates no significant association between common genetic variations in MOR and MOR-interacting proteins and smoking behaviors in Chinese men, and gives suggestive evidence that HINT1 rs3852209 may be related to smoking status. The findings require confirmation from further studies in additional larger samples. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - January 21, 2014 Category: Neurology Authors: Juan FangXiaohong WangBei He Source Type: research
Behavioral changes following PCB 153 exposure in the Spontaneously Hypertensive rat ¿ an animal model of Attention-Deficit/Hyperactivity disorder
Conclusions:
Exposure to PCB 153 seems to interact with several variables including strain, sex, dose, and time of testing. To the extent that the present findings can be generalized to humans, exposure effects of PCB 153 on ADHD behavior depends on amount of exposure, where high doses may aggravate ADHD symptoms in genetically vulnerable individuals. In normal controls, exposure may not constitute an environmental risk factor for developing the full range of ADHD symptoms, but can produce specific behavioral changes. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - January 9, 2014 Category: Neurology Authors: Espen JohansenFrode FonnumPer LausundS WalaasNora BærlandGrete WøienTerje Sagvolden Source Type: research
Behavioral changes following PCB 153 exposure in the Spontaneously Hypertensive rat - an animal model of Attention-Deficit/Hyperactivity disorder
Conclusions:
Exposure to PCB 153 seems to interact with several variables including strain, sex, dose, and time of testing. To the extent that the present findings can be generalized to humans, exposure effects of PCB 153 on ADHD behavior depends on amount of exposure, where high doses may aggravate ADHD symptoms in genetically vulnerable individuals. In normal controls, exposure may not constitute an environmental risk factor for developing the full range of ADHD symptoms, but can produce specific behavioral changes. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - January 9, 2014 Category: Neurology Authors: Espen JohansenFrode FonnumPer LausundS WalaasNora BærlandGrete WøienTerje Sagvolden Source Type: research
BAIAP2 exhibits association to childhood ADHD especially predominantly inattentive subtype in Chinese han subjects
Conclusions:
These above results indicated the possible involvement of BAIAP2 in the etiology of ADHD, especially ADHD-I. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - December 30, 2013 Category: Neurology Authors: Lu LiuLi SunZe-Hua LiHai-Mei LiLi-Ping WeiYu-Feng WangQiu-Jin Qian Source Type: research
Preliminary evidence about the effects of meditation on interoceptive sensitivity and social cognition
Conclusion:
Results suggest no influence of meditation practice in cardiac interoception and in most related social cognition measures. These negative results could be partially due to the fact that awareness of heartbeat sensations is not emphasized during mindfulness/vipassana meditation and may not be the best index of the awareness supported by the practice of meditation. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - December 23, 2013 Category: Neurology Authors: Margherita MelloniLucas SedeñoBlas CoutoMartin ReynosoCarlos GelorminiRoberto FavaloroAndrés Canales-JohnsonMariano SigmanFacundo ManesAgustin Ibanez Source Type: research
Experimental gastritis leads to anxiety- and depression-like behaviors in female but not male rats
We examined the effect of experimental gastritis on anxiety- and depression-like behaviors in male and female Sprague-Dawley rats, and evaluated potential mechanisms of action. Gastritis was induced by adding 0.1% (w/v) iodoacetamide (IAA) to the sterile drinking water for 7 days. Sucrose preference test assessed the depression-like behavior, open field test and elevated plus maze evaluated the anxiety-like behavior. IAA treatment induced gastric inflammation in rats of either gender. No behavioral abnormality or dysfunction of GI-brain axis was observed in male rats with IAA-induced gastritis. Anxiety- and depression-like...
Source: Behavioral and Brain Functions - December 17, 2013 Category: Neurology Authors: Jia LuoTao WangShan LiangXu HuWei LiFeng Jin Source Type: research
No association between serum cholesterol and death by suicide in patients with schizophrenia, bipolar affective disorder, or major depressive disorder
Conclusions:
Our results do not support the use of biological indicators such as serum total cholesterol to predict suicide risk among patients with a major psychiatric disorder. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - December 5, 2013 Category: Neurology Authors: Subin ParkKi Kyoung YiRiji NaAhyoung LimJin Pyo Hong Source Type: research
Differential effects of temporal regularity on auditory-evoked response amplitude: a decrease in silence and increase in noise
Conclusions:
Our results indicate that the human auditory system is able to involuntarily utilize temporal regularity in sound signals to modulate the neural activity in the auditory cortex in accordance with the surrounding acoustic environment. (Source: Behavioral and Brain Functions)
Source: Behavioral and Brain Functions - December 3, 2013 Category: Neurology Authors: Hidehiko OkamotoHenning TeismannSumru KeceliChristo PantevRyusuke Kakigi Source Type: research
Effects of the mGluR5 antagonist MPEP on ethanol withdrawal induced anxiety-like syndrome in rats
This study investigates the effects of the mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) on ethanol withdrawal induced anxiety using two behavioural paradigms. Male Wistar rats were fed a Modified Liquid Diet (MLD) containing low fat cow milk, sucrose, and maltodextrin with a gradual introduction of 2.4%, 4.8% and 7.2% ethanol for 20 days. Six hours into ethanol withdrawal, the rats were intraperitoneally injected with normal saline and MPEP (2.5, 5.0, 10, 20, 30 mg/kg) and were assessed for ethanol withdrawal induced anxiety-like syndrome using an automated elevated plus maze and an open field. MPEP at 10 m...
Source: Behavioral and Brain Functions - November 26, 2013 Category: Neurology Authors: Jaya KumarHermizi HapidinYvonne-Tee BeeZalina Ismail Source Type: research
