Arteriosclerosis, Thrombosis and Vascular Biology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Hepatic Inhibition of ANGPTL3 Mimics the Molecular Hallmarks of Hypothyroidism
Arterioscler Thromb Vasc Biol. 2024 Mar 7. doi: 10.1161/ATVBAHA.124.320817. Online ahead of print.NO ABSTRACTPMID:38450511 | DOI:10.1161/ATVBAHA.124.320817 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - March 7, 2024 Category: Cardiology Authors: Nayere Taebnia Volker M Lauschke Source Type: research

Prior Exposure to Experimental Preeclampsia Increases Atherosclerotic Plaque Inflammation in Atherogenic Mice
CONCLUSIONS: In atherogenic LDLR-KO mice, exposure to sFlt1-induced preeclampsia during pregnancy increases future atherosclerotic plaque inflammation, supporting the concept that preeclampsia directly exacerbates atherosclerotic inflammation independent of preexisting risk factors. This mechanism may contribute to ischemic vascular disease in women after preeclampsia pregnancy.PMID:38450510 | DOI:10.1161/ATVBAHA.123.320474 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - March 7, 2024 Category: Cardiology Authors: Lauren A Biwer Joshua J Man Nicholas D Camarda Brigett V Carvajal S Ananth Karumanchi Iris Z Jaffe Source Type: research

TF-FVIIa PAR2- β-Arrestin in Mouse Signaling Sustains Organ Dysfunction in Coxsackievirus B3 Infection
CONCLUSIONS: These data provide insights into a TF-FVIIa signaling axis through PAR2-β-arrestin coupling that is a regulator of inflammation-triggered tissue repair and hemodynamic compromise in coxsackievirus B3 infection and can potentially be targeted with selective coagulation inhibitors.PMID:38385286 | DOI:10.1161/ATVBAHA.123.320157 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - February 22, 2024 Category: Cardiology Authors: Meike Kespohl Carl Christoph Goetzke Nadine Althof Clara Bredow Nicolas Kelm Sandra Pinkert Thomas Bukur Valesca Bukur Kristin Grunz Dilraj Kaur Arnd Heuser Michael M ülleder Martina Sauter Karin Klingel Hartmut Weiler Nikolaus Berndt Matthias M Gaida Wo Source Type: research

Use of Genomics to Develop Novel Therapeutics and Personalize Hypertension Therapy
Arterioscler Thromb Vasc Biol. 2024 Feb 22. doi: 10.1161/ATVBAHA.123.319220. Online ahead of print.ABSTRACTHypertension is a prevalent public health problem, contributing to >10 million deaths annually. Though multiple therapeutics exist, many patients suffer from treatment-resistant hypertension or try several medications before achieving blood pressure control. Genomic advances offer mechanistic understanding of blood pressure variability, therapeutic targets, therapeutic response, and promise a stratified approach to treatment of primary hypertension. Cyclic guanosine monophosphate augmentation, aldosterone synthase ...
Source: Arteriosclerosis, Thrombosis and Vascular Biology - February 22, 2024 Category: Cardiology Authors: Emma F Magavern Vikas Kapil Manish Saxena Ajay Gupta Mark J Caulfield Source Type: research

Differences in Cardiometabolic Proteins in Pregnancy Prioritize Relevant Targets of Preeclampsia
CONCLUSIONS: These results demonstrate the value of performing targeted proteomics using a panel of cardiovascular biomarkers to identify biomarkers relevant to preeclampsia pathophysiology and highlight the need for larger multiomic studies to define modifiable pathways of surveillance and intervention upstream to preeclampsia diagnosis.PMID:38385288 | DOI:10.1161/ATVBAHA.124.320737 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - February 22, 2024 Category: Cardiology Authors: Kathryn J Lindley Andrew Perry Marni Jacobs Lauren Petty Kaushik Amancherla Shilin Zhao Claire Barker Victor G Davila-Roman Sadiya S Khan Sarah S Osmundson Kahraman Tanriverdi Jane E Freedman Jennifer Below Ravi V Shah Louise C Laurent Source Type: research

Inhibition of IL-1 Ameliorates Cardiac Dysfunction and Arrhythmias in a Murine Model of Kawasaki Disease
CONCLUSIONS: Our results characterize the electrophysiological abnormalities associated with L casei cell wall extract-induced KD and show that IL-1Ra is more effective in preventing KD-induced myocardial dysfunction and arrhythmias than anti-TNFα therapy. These findings support the advancement of clinical trials using IL-1Ra in patients with KD.PMID:38385289 | DOI:10.1161/ATVBAHA.123.320382 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - February 22, 2024 Category: Cardiology Authors: Thassio Mesquita Yen-Nien Lin Shuang Chen Youngho Lee Rodrigo Miguel-Dos-Santos Asli E Atici Michael C Fishbein Magali Noval Rivas Moshe Arditi Eugenio Cingolani Source Type: research