Challenges of Carbapenem-resistant < em > Pseudomonas aeruginosa < /em > in Infection Control and Antibiotic Management
Ann Lab Med. 2024 Jan 1;44(1):1-2. doi: 10.3343/alm.2024.44.1.1. Epub 2023 Sep 4.NO ABSTRACTPMID:37665279 | PMC:PMC10485858 | DOI:10.3343/alm.2024.44.1.1 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - September 4, 2023 Category: Laboratory Medicine Authors: Young Jin Kim Hee Jae Huh Heungsup Sung Source Type: research

New Insights Into SARS-CoV-2-specific Antibody Levels in Kidney Transplantation Recipients After Three Vaccination Doses
Ann Lab Med. 2024 Jan 1;44(1):3-5. doi: 10.3343/alm.2024.44.1.3. Epub 2023 Sep 4.NO ABSTRACTPMID:37665280 | PMC:PMC10485850 | DOI:10.3343/alm.2024.44.1.3 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - September 4, 2023 Category: Laboratory Medicine Authors: Hyunhye Kang Eun-Jee Oh Source Type: research

Bias in Laboratory Medicine: The Dark Side of the Moon
Ann Lab Med. 2024 Jan 1;44(1):6-20. doi: 10.3343/alm.2024.44.1.6. Epub 2023 Sep 4.ABSTRACTPhysicians increasingly use laboratory-produced information for disease diagnosis, patient monitoring, treatment planning, and evaluations of treatment effectiveness. Bias is the systematic deviation of laboratory test results from the actual value, which can cause misdiagnosis or misestimation of disease prognosis and increase healthcare costs. Properly estimating and treating bias can help to reduce laboratory errors, improve patient safety, and considerably reduce healthcare costs. A bias that is statistically and medically signifi...
Source: Annals of Laboratory Medicine - September 4, 2023 Category: Laboratory Medicine Authors: Abdurrahman Coskun Source Type: research

Ionized Magnesium Correlates With Total Blood Magnesium in Pediatric Patients Following Kidney Transplant
CONCLUSIONS: tMg and iMg exhibited strong correlation following kidney transplantation. However, iCa may not be an accurate surrogate for iMg. Determining the effect of Mg supplementation and the Mg concentration where supplementation is clinically necessary are important next steps.PMID:37665282 | PMC:PMC10485856 | DOI:10.3343/alm.2024.44.1.21 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - September 4, 2023 Category: Laboratory Medicine Authors: Denise C Hasson Shruthi Mohan James E Rose Kyle A Merrill Stuart L Goldstein Stefanie W Benoit Charles D Varnell Source Type: research

Comparison of Direct and Extraction Immunoassay Methods With Liquid Chromatography-Tandem Mass Spectrometry Measurement of Urinary Free Cortisol for the Diagnosis of Cushing's Syndrome
CONCLUSIONS: Commercially available immunoassays for measuring UFC show different levels of analytical consistency compared to LC-MS/MS. Abbott-D, Siemens-E, and Beckman-E have high diagnostic accuracy for CS.PMID:37665283 | PMC:PMC10485861 | DOI:10.3343/alm.2024.44.1.29 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - September 4, 2023 Category: Laboratory Medicine Authors: Danni Mu Jiadan Fang Songlin Yu Yichen Ma Jin Cheng Yingying Hu Ailing Song Fang Zhao Qi Zhang Zhihong Qi Kui Zhang Liangyu Xia Ling Qiu Huijuan Zhu Xinqi Cheng Source Type: research

Changing Genotypic Distribution, Antimicrobial Susceptibilities, and Risk Factors of Urinary Tract Infection Caused by Carbapenemase-Producing < em > Pseudomonas aeruginosa < /em >
CONCLUSIONS: The changing trend and genetic distribution of CPPA isolates emphasize the need for relentless monitoring to control further dissemination. The use of carbapenems, ICU stay, and WBC count should be considered risk factors, and aggressive antibiotic stewardship programs and monitoring may serve to prevent worse outcomes.PMID:37665284 | PMC:PMC10485864 | DOI:10.3343/alm.2024.44.1.38 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - September 4, 2023 Category: Laboratory Medicine Authors: Seri Jeong Kibum Jeon Nuri Lee Min-Jeong Park Wonkeun Song Source Type: research

Comparative Genomic Analysis of Staphylococcal Cassette Chromosome < em > mec < /em > Type V < em > Staphylococcus aureus < /em > Strains and Estimation of the Emergence of SCC < em > mec < /em > V Clinical Isolates in Korea
CONCLUSIONS: Most Korean SCCmec V strains may have emerged during 2000-2010. A unique MRSA SCCmec V strain, ST72 (a Korean common type of community-associated MRSA), was also identified. The genomic dynamics of this clone with a zoonotic background should be monitored to accurately understand MRSA evolution.PMID:37665285 | PMC:PMC10485862 | DOI:10.3343/alm.2024.44.1.47 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - September 4, 2023 Category: Laboratory Medicine Authors: Takashi Takahashi Hyaekang Kim Han-Sung Kim Hyun Soo Kim Wonkeun Song Jae-Seok Kim Source Type: research

Clinical Usefulness of a Cell-based Assay for Detecting Myelin Oligodendrocyte Glycoprotein Antibodies in Central Nervous System Inflammatory Disorders
CONCLUSIONS: The in-house CBA for MOG-Abs demonstrated reliable results and can potentially be used to evaluate CNS inflammatory disorders. A comprehensive, long-term study with a large patient population would clarify the clinical significance of MOG-Abs.PMID:37665286 | PMC:PMC10485852 | DOI:10.3343/alm.2024.44.1.56 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - September 4, 2023 Category: Laboratory Medicine Authors: Jin Myoung Seok Patrick Waters Mi Young Jeon Hye Lim Lee Seol-Hee Baek Jin-Sung Park Sa-Yoon Kang Ohyun Kwon Jeeyoung Oh Byung-Jo Kim Kyung-Ah Park Sei Yeul Oh Byoung Joon Kim Ju-Hong Min Source Type: research

Association Between Low Anti-spike Antibody Levels After the Third Dose of SARS-CoV-2 Vaccination and Hospitalization due to Symptomatic Breakthrough Infection in Kidney Transplant Recipients
CONCLUSIONS: Low anti-spike IgG levels after third vaccination in kidney transplant recipients were associated with symptomatic breakthrough infection and, particularly, with hospitalization during the Omicron surge. These data can be used to identify patients requiring additional protective measures, such as passive immunization using monoclonal antibodies.PMID:37665287 | PMC:PMC10485855 | DOI:10.3343/alm.2024.44.1.64 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - September 4, 2023 Category: Laboratory Medicine Authors: Ahram Han Sangil Min Eun-Ah Jo Hajeong Lee Yong Chul Kim Seung Seok Han Hee Gyung Kang Yo Han Ahn Inseong Oh Eun Young Song Jongwon Ha Source Type: research

Prediction of Mid-term Platelet Transfusion in Stable Trauma Patients Using Rotational Thromboelastometry
CONCLUSIONS: FIBTEM and EXTEM can reliably predict mid-term platelet transfusion in trauma patients. FIBTEM, EXTEM, and PLTEM parameters correlate with conventional coagulation tests (platelets and fibrinogen).PMID:37665288 | PMC:PMC10485857 | DOI:10.3343/alm.2024.44.1.74 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - September 4, 2023 Category: Laboratory Medicine Authors: Ha Jin Lim Hyunseok Jang Naa Lee Euisung Jeong Yunchul Park Younggoun Jo Jungchul Kim Young Eun Lee Hyun-Jung Choi Seung-Jung Kee Jong Hee Shin Myung Geun Shin Source Type: research

Evaluation of Group Genetic Counseling Sessions via a Metaverse-based Application
CONCLUSIONS: The metaverse platform would be acceptable as an alternative group genetic counseling service. More studies are needed to investigate how, for whom, and in what circumstances metaverse can be effectively utilized.PMID:37665289 | PMC:PMC10485865 | DOI:10.3343/alm.2024.44.1.82 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - September 4, 2023 Category: Laboratory Medicine Authors: Boeun Yoo Arang Kim Hye Sung Moon Min-Kyung So Tae-Dong Jeong Kyoung Eun Lee Byung-In Moon Jungwon Huh Source Type: research

< em > In Vitro < /em > Activity of Benzimidazole (SPR719) Against Clinical Isolates of Nontuberculous Mycobacteria With and Without Clarithromycin or Amikacin Resistance
Ann Lab Med. 2024 Jan 1;44(1):92-96. doi: 10.3343/alm.2024.44.1.92. Epub 2023 Sep 4.ABSTRACTLimited data are available regarding the in vitro activity of SPR719, a derivative of benzimidazole, against diverse nontuberculous mycobacteria (NTM) species. We investigated the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of SPR719 against clinical NTM isolates, including clarithromycin- and amikacin-resistant strains. NTM isolates were obtained from patients with NTM-pulmonary disease caused by various NTM species, including Mycobacterium avium complex, M. abscessus (subspecies abscessus an...
Source: Annals of Laboratory Medicine - September 4, 2023 Category: Laboratory Medicine Authors: Dae Hun Kim Sungmin Zo Su-Young Kim Byung Woo Jhun Source Type: research

The First Korean Hemoglobinopathy With Unique Hemoglobin Electrophoresis Results Diagnosed as Hemoglobin Boras
Ann Lab Med. 2024 Jan 1;44(1):97-99. doi: 10.3343/alm.2024.44.1.97. Epub 2023 Sep 4.NO ABSTRACTPMID:37665291 | PMC:PMC10485859 | DOI:10.3343/alm.2024.44.1.97 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - September 4, 2023 Category: Laboratory Medicine Authors: Jeongyun Bae Won Kee Ahn Jaehyeok Jang Hanmil Jang Hyein Kang John Hoon Rim Seung Min Hahn Jung Woo Han Chuhl Joo Lyu Jong-Baeck Lim Source Type: research

Skeletal Muscle Mass Measurement via Bioelectrical Impedance Analysis as an Aid to Screen for Chronic Kidney Disease in Routine Health Checkups
Ann Lab Med. 2024 Jan 1;44(1):100-102. doi: 10.3343/alm.2024.44.1.100. Epub 2023 Sep 4.NO ABSTRACTPMID:37665292 | PMC:PMC10485860 | DOI:10.3343/alm.2024.44.1.100 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - September 4, 2023 Category: Laboratory Medicine Authors: Seunghoo Lee Sangpil Yoon Sollip Kim Woochang Lee Sail Chun Won-Ki Min Source Type: research

Effectiveness of Unified Computerized Reporting of Point-of-Care Glucose Meter Test
Ann Lab Med. 2024 Jan 1;44(1):103-106. doi: 10.3343/alm.2024.44.1.103. Epub 2023 Sep 4.NO ABSTRACTPMID:37665293 | PMC:PMC10485851 | DOI:10.3343/alm.2024.44.1.103 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - September 4, 2023 Category: Laboratory Medicine Authors: Sooin Choi Dughyun Choi Soo Jeong Choi Jin Kuk Kim You Kyoung Lee Yong-Wha Lee Source Type: research