Comprehensive analysis of orbital lymphoma in a Turkish cohort: clinical characteristics, histological subtypes, treatment modalities, prognostic factors, and implications for management
This study contributes to our understanding of OLs and provides a foundation for further investigations in this field. Male gender, presence of B symptoms, advanced stage, secondary orbital lymphoma, aggressive histological subtype, and elevated serum lactate dehydrogenase levels were associated with poorer (either inferior or worse) progression-free survival.Graphical abstract (Source: Annals of Hematology)
Source: Annals of Hematology - December 7, 2023 Category: Hematology Source Type: research
Ropeginterferon phase 2 randomized study in low-risk polycythemia vera: 5-year drug survival and efficacy outcomes
In conclusion, to improve the effectiveness of Ropeg, we suggest increasing the dose and using it earl ier driven by high phlebotomy need in the first 6 months post-diagnosis. (Source: Annals of Hematology)
Source: Annals of Hematology - December 7, 2023 Category: Hematology Source Type: research
Comprehensive analysis of orbital lymphoma in a Turkish cohort: clinical characteristics, histological subtypes, treatment modalities, prognostic factors, and implications for management
This study contributes to our understanding of OLs and provides a foundation for further investigations in this field. Male gender, presence of B symptoms, advanced stage, secondary orbital lymphoma, aggressive histological subtype, and elevated serum lactate dehydrogenase levels were associated with poorer (either inferior or worse) progression-free survival.Graphical abstract (Source: Annals of Hematology)
Source: Annals of Hematology - December 7, 2023 Category: Hematology Source Type: research
Ropeginterferon phase 2 randomized study in low-risk polycythemia vera: 5-year drug survival and efficacy outcomes
In conclusion, to improve the effectiveness of Ropeg, we suggest increasing the dose and using it earl ier driven by high phlebotomy need in the first 6 months post-diagnosis. (Source: Annals of Hematology)
Source: Annals of Hematology - December 7, 2023 Category: Hematology Source Type: research
Immunophenotypic profile defines cytogenetic stability and unveils distinct prognoses in patients with newly-diagnosed multiple myeloma (NDMM)
AbstractPrognostic significance of multiple immune antigens in multiple myeloma has been well established. However, a level of uncertainty remains regarding the intrinsic relationship between immunophenotypes and cytogenetic stability and precise risk stratification. To address these unresolved issues, we conducted a study involving 1389 patients enrolled in the National Longitudinal Cohort of Hematological Diseases in China (NCT04645199). Our results revealed that the correlation between antigen expression and cytogenetics is more prominent than cytopenia or organ dysfunction. Most immune antigens, apart from CD38, CD138,...
Source: Annals of Hematology - December 5, 2023 Category: Hematology Source Type: research
Castleman disease- demographics, associations, and outcomes: an analysis of adult 791 cases
Conclusion: This study contributes valuable insights into CD, a rare and clinically heterogeneous disease. It underscores the importance of recognizing its associations and complications. Addit ionally, it highlights the need for further research and improved diagnostic and treatment guidelines to address the complexity of this condition. (Source: Annals of Hematology)
Source: Annals of Hematology - December 2, 2023 Category: Hematology Source Type: research
Correction to: Molecular characteristics of hereditary red blood cell membrane disorders in Thailand: a multi ‑center registry
(Source: Annals of Hematology)
Source: Annals of Hematology - December 2, 2023 Category: Hematology Source Type: research
Castleman disease- demographics, associations, and outcomes: an analysis of adult 791 cases
Conclusion: This study contributes valuable insights into CD, a rare and clinically heterogeneous disease. It underscores the importance of recognizing its associations and complications. Addit ionally, it highlights the need for further research and improved diagnostic and treatment guidelines to address the complexity of this condition. (Source: Annals of Hematology)
Source: Annals of Hematology - December 2, 2023 Category: Hematology Source Type: research
Correction to: Molecular characteristics of hereditary red blood cell membrane disorders in Thailand: a multi ‑center registry
(Source: Annals of Hematology)
Source: Annals of Hematology - December 2, 2023 Category: Hematology Source Type: research
A case of sudden hearing loss in a patient with chronic myelomonocytic leukemia
AbstractChronic myelomonocytic leukemia is a myeloid stem cell disease characterized by an abnormal production and accumulation of monocytic cells in association with other signs of myeloproliferation. Extramedullary manifestations of CMML are common and can affect the spleen, liver skin, and lymph nodes. However, otologic manifestations are extremely rare and could have occurred from either direct leukemic infiltration, hemorrhage of the cochlea, labyrinth, leukostasis, or infection. There is no standard treatment protocol for sensorineural hearing loss in CMML patients. More research is needed to improve the understandin...
Source: Annals of Hematology - December 1, 2023 Category: Hematology Source Type: research
Clonal myeloid disorders following CAR T-cell therapy
(Source: Annals of Hematology)
Source: Annals of Hematology - December 1, 2023 Category: Hematology Source Type: research
Ibrutinib plus rituximab and lenalidomide for primary intestinal diffuse large B-cell lymphoma relapsed after anti-CD19 CAR-T cell therapy: a case report
(Source: Annals of Hematology)
Source: Annals of Hematology - December 1, 2023 Category: Hematology Source Type: research
Clonal hematopoiesis with TET2 mutations spawning synchronous primary central nervous system lymphoma and myelodysplastic syndrome
(Source: Annals of Hematology)
Source: Annals of Hematology - December 1, 2023 Category: Hematology Source Type: research
