Neuro-urological diagnostics and treatment of non-traumatic/degenerative neurogenic lower urinary tract dysfunction exemplified by multiple sclerosis
This article presents the current diagnostic and therapeutic options of neurogenic lower urinary tract dysfunction in multiple sclerosis. A crucial issue is the initial delay in diagnosis, not least due to a lack of communication between neurologists and urologists. Initial indicators of the presence of neurogenic lower urinary tract dysfunction can be obtained by actively asking about the subjective presence of symptoms such as urinary incontinence or the occurrence of urinary tract infections. However, a subjective lack of symptoms does not rule out a neurogenic lower urinary tract dysfunction. Regardless of the stage of...
Source: Aktuelle Urologie - April 23, 2024 Category: Urology & Nephrology Authors: Ines Kurze Anke K Jaekel Source Type: research

The 1-cm lower calyx calculus: SWT, URS or Mini-PCNL? Guidelines vs. reality.
Aktuelle Urol. 2024 Apr 23. doi: 10.1055/a-2290-7250. Online ahead of print.ABSTRACTUrinary stones of the upper urinary tract can be considered a widespread public health concern due to their high incidence and prevalence and their health policy-related and financial implications. A significant proportion of newly diagnosed kidney stones are lower-pole stones, i.e., stones affecting the lower calyx group of the renal pelvicalyceal system. These are often diagnosed by chance, i.e., as incidental findings during ultrasound or CT scans performed for other reasons, or as "secondary stones" detected during the diagnostic work-u...
Source: Aktuelle Urologie - April 23, 2024 Category: Urology & Nephrology Authors: Peter Jochen Olbert Source Type: research

"Pressure kills kidneys": protection of the upper urinary tract through neuro-urological management
This article is intended to provide information about the epidemiology and complex pathogenetic mechanisms as well as the necessary diagnostic steps. Various medical, interventional and surgical treatment strategies are evaluated on the basis of current scientific findings, thus supporting the reader in the care of this complex patient group.PMID:38653468 | DOI:10.1055/a-2287-4933 (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - April 23, 2024 Category: Urology & Nephrology Authors: Fabian Quei ßert Andres Jan Schrader Source Type: research

How good are we really? Incidence of postoperative bleeding requiring intervention and intraoperative electrocoagulation during Thulium laser enucleation of the prostate
This study aimed to retrospectively analyse this complication in the treatment of benign prostatic enlargement. This study focuses on investigating potential causative factors for postoperative bleeding requiring intervention as well as the use of intraoperative electrocoagulation. A total of 503 ThuLEP procedures performed between 08/2021 and 07/2022 were examined. Postoperatively, 4.2% (n=21) of patients experienced bleeding requiring intervention. Study data revealed a significant association between these instances of bleeding and a high prostate volume (p=0.004), high enucleation weight (p=0.004), and intraoperative e...
Source: Aktuelle Urologie - April 17, 2024 Category: Urology & Nephrology Authors: Simon Filmar Jakob Schaefer Andreas J Gross Sophia Hook Fabio Mehrer Benedikt Becker Clemens Rosenbaum Christopher Netsch Source Type: research

Invasive neurostimulation in neuro-urology: state of the art
Aktuelle Urol. 2024 Apr 17. doi: 10.1055/a-2261-4792. Online ahead of print.ABSTRACTModulation or stimulation of the nerves supplying the lower urinary tract is a possible treatment option for dysfunction of the lower urinary tract, pelvic floor and rectum if conservative or minimally invasive treatment approaches fail. This overview shows the possibilities and limitations of sacral neuromodulation, sacral deafferentation with sacral anterior root stimulation and conus deafferentation.Sacral neuromodulation (SNM) is a procedure for the treatment of refractory pelvic floor dysfunction of various origins (idiopathic, neuroge...
Source: Aktuelle Urologie - April 17, 2024 Category: Urology & Nephrology Authors: Ines Kurze Ralf B öthig Arndt van Ophoven Source Type: research

How good are we really? Incidence of postoperative bleeding requiring intervention and intraoperative electrocoagulation during Thulium laser enucleation of the prostate
This study aimed to retrospectively analyse this complication in the treatment of benign prostatic enlargement. This study focuses on investigating potential causative factors for postoperative bleeding requiring intervention as well as the use of intraoperative electrocoagulation. A total of 503 ThuLEP procedures performed between 08/2021 and 07/2022 were examined. Postoperatively, 4.2% (n=21) of patients experienced bleeding requiring intervention. Study data revealed a significant association between these instances of bleeding and a high prostate volume (p=0.004), high enucleation weight (p=0.004), and intraoperative e...
Source: Aktuelle Urologie - April 17, 2024 Category: Urology & Nephrology Authors: Simon Filmar Jakob Schaefer Andreas J Gross Sophia Hook Fabio Mehrer Benedikt Becker Clemens Rosenbaum Christopher Netsch Source Type: research

Invasive neurostimulation in neuro-urology: state of the art
Aktuelle Urol. 2024 Apr 17. doi: 10.1055/a-2261-4792. Online ahead of print.ABSTRACTModulation or stimulation of the nerves supplying the lower urinary tract is a possible treatment option for dysfunction of the lower urinary tract, pelvic floor and rectum if conservative or minimally invasive treatment approaches fail. This overview shows the possibilities and limitations of sacral neuromodulation, sacral deafferentation with sacral anterior root stimulation and conus deafferentation.Sacral neuromodulation (SNM) is a procedure for the treatment of refractory pelvic floor dysfunction of various origins (idiopathic, neuroge...
Source: Aktuelle Urologie - April 17, 2024 Category: Urology & Nephrology Authors: Ines Kurze Ralf B öthig Arndt van Ophoven Source Type: research

Thulium or holmium laser or both: where will the journey take us?
This article aims to review the key technological differences between Ho:YAG lasers and pulsed thulium lasers and compare/discuss the initial clinical results for stone lithotripsy and laser enucleation.In-vitro studies have demonstrated the technical superiority of TFL compared with Ho:YAG lasers. However, as TFL is still a new technology, only limited studies are available to date, and optimal settings for lithotripsy have not been established. For enucleation, the differences of TFL compared with a high-power Ho:YAG laser seem to be clinically irrelevant. Initial studies on pulsed Tm:YAG lasers show good results, but th...
Source: Aktuelle Urologie - April 11, 2024 Category: Urology & Nephrology Authors: Benedikt Becker Sophia Hook Andreas J Gross Clemens Rosenbaum Simon Filmar Jonas Herrmann Christopher Netsch Source Type: research

Thulium or holmium laser or both: where will the journey take us?
This article aims to review the key technological differences between Ho:YAG lasers and pulsed thulium lasers and compare/discuss the initial clinical results for stone lithotripsy and laser enucleation.In-vitro studies have demonstrated the technical superiority of TFL compared with Ho:YAG lasers. However, as TFL is still a new technology, only limited studies are available to date, and optimal settings for lithotripsy have not been established. For enucleation, the differences of TFL compared with a high-power Ho:YAG laser seem to be clinically irrelevant. Initial studies on pulsed Tm:YAG lasers show good results, but th...
Source: Aktuelle Urologie - April 11, 2024 Category: Urology & Nephrology Authors: Benedikt Becker Sophia Hook Andreas J Gross Clemens Rosenbaum Simon Filmar Jonas Herrmann Christopher Netsch Source Type: research

Thulium or holmium laser or both: where will the journey take us?
This article aims to review the key technological differences between Ho:YAG lasers and pulsed thulium lasers and compare/discuss the initial clinical results for stone lithotripsy and laser enucleation.In-vitro studies have demonstrated the technical superiority of TFL compared with Ho:YAG lasers. However, as TFL is still a new technology, only limited studies are available to date, and optimal settings for lithotripsy have not been established. For enucleation, the differences of TFL compared with a high-power Ho:YAG laser seem to be clinically irrelevant. Initial studies on pulsed Tm:YAG lasers show good results, but th...
Source: Aktuelle Urologie - April 11, 2024 Category: Urology & Nephrology Authors: Benedikt Becker Sophia Hook Andreas J Gross Clemens Rosenbaum Simon Filmar Jonas Herrmann Christopher Netsch Source Type: research

Thulium or holmium laser or both: where will the journey take us?
This article aims to review the key technological differences between Ho:YAG lasers and pulsed thulium lasers and compare/discuss the initial clinical results for stone lithotripsy and laser enucleation.In-vitro studies have demonstrated the technical superiority of TFL compared with Ho:YAG lasers. However, as TFL is still a new technology, only limited studies are available to date, and optimal settings for lithotripsy have not been established. For enucleation, the differences of TFL compared with a high-power Ho:YAG laser seem to be clinically irrelevant. Initial studies on pulsed Tm:YAG lasers show good results, but th...
Source: Aktuelle Urologie - April 11, 2024 Category: Urology & Nephrology Authors: Benedikt Becker Sophia Hook Andreas J Gross Clemens Rosenbaum Simon Filmar Jonas Herrmann Christopher Netsch Source Type: research

Oncological relevance of neuro-urological diseases
Aktuelle Urol. 2024 Apr 10. doi: 10.1055/a-2269-1222. Online ahead of print.ABSTRACTApart from a few exceptions, there is currently little scientific evidence on the oncological relevance of neuro-urological diseases. Most research has been conducted into the association between long-term spinal cord injury with its consequences for the lower urinary tract and the occurrence of bladder cancer. These cancers differ in many ways from bladder cancers in patients without spinal cord injury: patients are 20 years younger on average, tumours are very often already muscle-invasive and poorly differentiated with a high proportion ...
Source: Aktuelle Urologie - April 10, 2024 Category: Urology & Nephrology Authors: Ralf B öthig Wolfgang Sch öps Birgitt Kowald Klaus Golka Source Type: research

Large Language Models for Rapid Simplification of Quality Assurance Data Input: Field Trial with Real Data in the Context of Tumour Documentation in Urology
CONCLUSION: The use of generative AI in the context of search, transfer, and interpretation tasks in the creation of tumor documentation is a promising approach. However, its implementation in practical applications must be closely monitored, and the optimal interaction between man and machine should continue to be evaluated and must be accompanied by tools and task-specific prompts.PMID:38599593 | DOI:10.1055/a-2281-8015 (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - April 10, 2024 Category: Urology & Nephrology Authors: Johannes Frank Axel S Merseburger Johannes Landmesser Silvia Brozat-Essen Peter Schramm Laura Freimann Alexander Kleehaus Christian Elsner Source Type: research

Development of endoscopic enucleation of the prostate
This article deals with lasers from their initial description to the most advanced applications in the treatment of benign prostate enlargement.PMID:38599594 | DOI:10.1055/a-2286-1243 (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - April 10, 2024 Category: Urology & Nephrology Authors: Andreas J Gross Clemens Rosenbaum Benedikt Becker Christopher Netsch Source Type: research

Oncological relevance of neuro-urological diseases
Aktuelle Urol. 2024 Apr 10. doi: 10.1055/a-2269-1222. Online ahead of print.ABSTRACTApart from a few exceptions, there is currently little scientific evidence on the oncological relevance of neuro-urological diseases. Most research has been conducted into the association between long-term spinal cord injury with its consequences for the lower urinary tract and the occurrence of bladder cancer. These cancers differ in many ways from bladder cancers in patients without spinal cord injury: patients are 20 years younger on average, tumours are very often already muscle-invasive and poorly differentiated with a high proportion ...
Source: Aktuelle Urologie - April 10, 2024 Category: Urology & Nephrology Authors: Ralf B öthig Wolfgang Sch öps Birgitt Kowald Klaus Golka Source Type: research