[Mechanisms of Resistance in Antihormone Therapies of Advanced Prostate Cancer].
Abstract With the development of Abiraterone and Enzalutamide new treatment option have become available in addition to Docetaxel for first-line treatment of castration resistant prostate cancer. However, resistance and ultimately failure occurs inevitably with all available treatment options. Moreover, cross-resistance leads to considerably reduced efficacy in second-line treatment. Preclinical data suggest discriminative mechanisms of resistance development for Abiraterone and Enzalutamide. Clinical confirmation of these putative mechanisms for treatment failure might facilitate recommendations for future sequen...
Source: Aktuelle Urologie - January 27, 2016 Category: Urology & Nephrology Authors: Thelen P, Gschwend J, Wolff JM, Miller K Tags: Aktuelle Urol Source Type: research

[Partial Nephrectomy in cT1 Renal Tumours: Conventional Laparoscopic Partial Nephrectomy Compared with LESS Partial Nephrectomy in SITUS Technique].
Conclusions: LESS partial nephrectomy in SITUS technique is an attractive alternative to conventional laparoscopic and open partial nephrectomy. PMID: 26574950 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - November 17, 2015 Category: Urology & Nephrology Authors: Wolters M, Wohlatz L, Neumann T, Jutzi S, Peters I, von Klot C, Imkamp F, Lutze B, Kuczyk MA, Nagele U, Herrmann TR Tags: Aktuelle Urol Source Type: research

[Chronic Constipation: A Geriatric Syndrome with Urological Implications].
n A Abstract Chronic constipation, faecal and urinary incontinence are a geriatric syndrome. Chronic constipation is particularly important for the field of urology as it may be considered to trigger urological incontinence problems. Both chronic constipation and urinary incontinence are age-dependent symptoms, which are associated with a significant impact on quality of life. Chronic constipation must be taken into consideration during the diagnostic work-up and treatment of urinary incontinence. PMID: 26574951 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - November 17, 2015 Category: Urology & Nephrology Authors: Füsgen I, Wiedemann A Tags: Aktuelle Urol Source Type: research

[Characteristic Features of Urinary Incontinence - Diagnostic Investigation in Geriatric Patients].
Abstract Urinary incontinence is a common medical and social problem in elderly people. It leads to a massive reduction in the quality of life of affected persons and their dependants and causes an enormous socio-economic burden, which will increase significantly within the next years and decades as the age structure of the German population changes. Successful treatment of urinary incontinence in the elderly requires a good pathophysiological understanding of the underlying problem as well as individually tailored diagnostic procedures, which must be oriented at the patient's wishes, the social environment and th...
Source: Aktuelle Urologie - November 11, 2015 Category: Urology & Nephrology Authors: Kirschner-Hermanns R, Anding R Tags: Aktuelle Urol Source Type: research

[Systemic Treatment of Metastatic Renal Cell Cancer - Back to the Future?]
d V Abstract A variety of therapeutic agents are currently available for the systemic treatment of metastatic renal cell carcinoma (mRCC). It was only when targeted treatment was developed in the past decade that a significant improvement was achieved in tumour therapy. This also led to the development of sequential treatment for mRCC.7 molecular targeted agents are available today (axitinib, bevacizumab/ IFNα, everolimus, pazopanib, sorafenib, sunitinib, and temsirolimus). Due to the individualisation of treatment it remains a challenge to choose the most appropriate drug in a given setting, with the choice...
Source: Aktuelle Urologie - November 10, 2015 Category: Urology & Nephrology Authors: Ivanyi P, Grünwald V Tags: Aktuelle Urol Source Type: research

[Challenges for Urologists in the Care of Patients with Lynch Syndrome: Example of A Patient with Muir-Torre Syndrome, A Subtype of Lynch Syndrome].
We report on a patient with various types of LS-associated cancers and cancers without a known association with LS, who died from multifocal metastasis of urothelial cancer. This case report shows that close interdisciplinary cooperation is mandatory for the treatment of patients with complex diseases. PMID: 26509248 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - October 28, 2015 Category: Urology & Nephrology Authors: Löhmann C, Kächele V, Martinschek A, Sparwasser C Tags: Aktuelle Urol Source Type: research

[Molecular Concepts of Immunomodulation for the Treatment of Metastatic Renal Cell Carcinomas: Where are We Now?]
Abstract The introduction of molecular targeted agents has started to transform the treatment of metastatic renal cell carcinoma (mRCC), leading to a significant improvement of the prognosis of patients affected by that disease. However, treatment of metastatic disease still remains challenging as almost all patients will experience tumour progression and long-term survivors are very rare. This clearly warrants a continued search for improved treatment options. In recent years, the development of new substances and treatment approaches involving the targeted activation and modulation of the immune system have move...
Source: Aktuelle Urologie - October 21, 2015 Category: Urology & Nephrology Authors: Goebell PJ, Bedke J Tags: Aktuelle Urol Source Type: research

Kinderurologie - Biofeedback bei Blasenentleerungsstörungen.
Kinderurologie - Biofeedback bei Blasenentleerungsstörungen. Aktuelle Urol. 2015 Sep;46(5):345-346 Authors: PMID: 26394076 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Ausschreibung - C.E. Alken-Preis 2015.
Authors: PMID: 26394077 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Ossär metastasiertes Prostatakarzinom - Zytoreduktive radikale Prostatektomie von Vorteil?
Ossär metastasiertes Prostatakarzinom - Zytoreduktive radikale Prostatektomie von Vorteil? Aktuelle Urol. 2015 Sep;46(5):348-350 Authors: PMID: 26394078 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Interstitielle Zystitis - Behandlung mit Natriumpentosanpolysulfat.
Authors: PMID: 26394079 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

67. DGU-Kongress - Urologen wollen Psychoonkologie stärken.
67. DGU-Kongress - Urologen wollen Psychoonkologie stärken. Aktuelle Urol. 2015 Sep;46(5):353 Authors: PMID: 26394080 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Präventionsgesetz - Jungensprechstunde integrieren!
Präventionsgesetz - Jungensprechstunde integrieren! Aktuelle Urol. 2015 Sep;46(5):354 Authors: PMID: 26394081 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Buchbesprechung - Recht für Ärzte von A-Z.
Buchbesprechung - Recht für Ärzte von A-Z. Aktuelle Urol. 2015 Sep;46(5):355 Authors: Levien P PMID: 26394082 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Authors: Levien P Tags: Aktuelle Urol Source Type: research

AUO - Therapie des unbehandelten lokal fortgeschrittenen oder metastasierten RCC.
Authors: PMID: 26394083 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

"Hochkleben" der Bauchfellschürze bei extremer Adipositas.
"Hochkleben" der Bauchfellschürze bei extremer Adipositas. Aktuelle Urol. 2015 Sep;46(5):358 Authors: Wiedemann A PMID: 26394084 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Authors: Wiedemann A Tags: Aktuelle Urol Source Type: research

Medizin weltweit - In den Fußstapfen Avicennas.
Medizin weltweit - In den Fußstapfen Avicennas. Aktuelle Urol. 2015 Sep;46(5):360-361 Authors: PMID: 26394085 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

So beraten Sie Ihre Patienten - Komplementärmedizin bei Krebs.
So beraten Sie Ihre Patienten - Komplementärmedizin bei Krebs. Aktuelle Urol. 2015 Sep;46(5):363-364 Authors: PMID: 26394086 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Aktuelles aus der Community - Mein Interessensgebiet Urologie.
Authors: PMID: 26394087 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Urologie umfasst mehr - Editorial zum Themenheft.
Authors: PMID: 26394176 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Elektronische Gesundheitskarte - Bundeskabinett beschließt den E-Health-Gesetzentwurf.
Elektronische Gesundheitskarte - Bundeskabinett beschließt den E-Health-Gesetzentwurf. Aktuelle Urol. 2015 Sep;46(5):366-367 Authors: PMID: 26394177 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

[Current Shortcomings in the Treatment of Cryptorchidism - Analysis Performed by a Paediatrician].
Abstract Cryptorchidism is the most common disorder in paediatric surgery in the Western world and a major risk factor for subfertility and malignancy. In 2009, German national guidelines were changed to recommend that treatment for undescended testes should be completed by the age of 1 instead of 2. However, the share of boys undergoing orchidopexy for cryptorchidism within the first year of life has only marginally increased in response to the guideline of the Association of the Scientific Medical Societies in Germany (AWMF). The number of orchidopexies performed in children below the age of 1 is too low both in...
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Authors: Hensel KO, Wirth S Tags: Aktuelle Urol Source Type: research

[Female Urethral Obstruction and Bladder Neck Stenosis - Fact or Myth - How to Proceed].
Abstract The female urethra is probably the most neglected organ in women. Female urethral stricture and primary bladder neck obstruction are rare clinical entities. Traditional and new surgical techniques have been described for the treatment of female urethral stricture. However, they are based on limited data. There is no consensus on best management. The techniques of urethroplasty all have a higher mean success rate (80-94%) than urethral dilatation (
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Authors: Gunnemann A, Liedl B, Palma PC, Yoshimura Y, Muctar S Tags: Aktuelle Urol Source Type: research

[Chronic Pelvic Pain: Alternative Treatment Methods].
Abstract Chronic pelvic pain has a negative impact on quality of life, resulting in a tremendous cost of illness. This condition has a multifactorial etiology and its treatment is often a frustrating experience for patients and therapists alike. Therefore, patients frequently initiate alternative medical treatment methods, which are explained below. PMID: 26378389 [PubMed - in process] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Authors: Moormann O Tags: Aktuelle Urol Source Type: research

[Asymptomatic Kidney Stones: Active Surveillance vs. Treatment].
l T Abstract The prevalence of kidney stones is increasing worldwide. Asymptomatic non-obstructing kidney stones are increasingly detected as an incidental finding on radiologic imaging, which has been performed more frequently over the last decades. Beside the current interventional treatment modalities such as extracorporeal shockwave lithotripsy (ESWL), ureterorenoscopy (URS) and percutaneous nephrolithotomy (PNL), active surveillance of asymptomatic kidney stones has been a focus of discussion lately, not only for attending physicians, but even more so for patients. The current German and European guidelines r...
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Authors: Neisius A, Thomas C, Roos FC, Hampel C, Fritsche HM, Bach T, Thüroff JW, Knoll T Tags: Aktuelle Urol Source Type: research

[In Process Citation].
PMID: 26378391 [PubMed - in process] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Authors: Wille S Tags: Aktuelle Urol Source Type: research

[In Process Citation].
PMID: 26378392 [PubMed - in process] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - September 1, 2015 Category: Urology & Nephrology Authors: Gunnemann A Tags: Aktuelle Urol Source Type: research

[How Useful is a Geriatric Assessment Prior or Urological Surgery with Regard to Cognitive Changes?]
Abstract Objective: Detection of changes in cognition after transurethral resection (TURP) or 180-Watt green-light XPS laser treatment (GLL) of the prostate is required by the German "Krankenhausbedarfsplan" which demands an interdisciplinary dialogue including special aspects of the operating discipline. This has as yet not been investigated in Germany or in Europe. Methods: Assessments of the cognitive capacity were made by application of the "Mini Mental State Examination" and the "Uhrentest" preoperatively and on postoperative day 2 in addition to documentation of clinical paramet...
Source: Aktuelle Urologie - August 4, 2015 Category: Urology & Nephrology Authors: Wiedemann A, Maykan R, Pennekamp J, Heppner H Tags: Aktuelle Urol Source Type: research

[Low Capacity Bladder: Dugs and/or Toilet Training].
Conclusion: Although experimental studies about micturition control in the CNS make a positive effect of behavioral interventions in overactive bladder more than likely, the literature reports on this topic remain inhomogeneous. PMID: 26241910 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - August 4, 2015 Category: Urology & Nephrology Authors: Wiedemann A, Heppner HJ Tags: Aktuelle Urol Source Type: research

Muskelinvasives Harnblasenkarzinom - Blasenerhaltende Therapie.
Authors: PMID: 26227116 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Peniskarzinom - Neue Therapiemethoden erhalten Lebensqualität.
Peniskarzinom - Neue Therapiemethoden erhalten Lebensqualität. Aktuelle Urol. 2015 Jul;46(4):272-273 Authors: PMID: 26227117 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Transplantation - Schwangerschaftshypertonie bzw. Präeklampsie nach Lebendnierenspende.
Transplantation - Schwangerschaftshypertonie bzw. Präeklampsie nach Lebendnierenspende. Aktuelle Urol. 2015 Jul;46(4):273-274 Authors: PMID: 26227118 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Varikozele - Geringere Testosteronproduktion.
Authors: PMID: 26227119 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Hodenverletzungen - Bei jungen Sportlern häufiger als gedacht.
Hodenverletzungen - Bei jungen Sportlern häufiger als gedacht. Aktuelle Urol. 2015 Jul;46(4):277-279 Authors: PMID: 26227120 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Ausschreibung - C.E. Alken-Preis 2015.
Authors: PMID: 26227121 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

PREFERE-Studie - Urologen begrüßen Fortführung.
PREFERE-Studie - Urologen begrüßen Fortführung. Aktuelle Urol. 2015 Jul;46(4):280 Authors: PMID: 26227122 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Urolithiasis - DGU gibt neue Leitlinie heraus.
Authors: PMID: 26227123 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Teilnehmer gesucht - Studie zur Therapie beim NMIBC.
Authors: PMID: 26227124 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Modifizierte Abdeckung für Eingriffe in Steinschnittlage.
Modifizierte Abdeckung für Eingriffe in Steinschnittlage. Aktuelle Urol. 2015 Jul;46(4):284-285 Authors: Eisenblätter K, Wiedemann A PMID: 26227125 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Authors: Eisenblätter K, Wiedemann A Tags: Aktuelle Urol Source Type: research

Medizin weltweit - Ärzte am Drehkreuz zur Welt.
Medizin weltweit - Ärzte am Drehkreuz zur Welt. Aktuelle Urol. 2015 Jul;46(4):286-287 Authors: PMID: 26227126 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Ein Team zielgerichtet leiten - Der Arzt als Führungskraft.
Ein Team zielgerichtet leiten - Der Arzt als Führungskraft. Aktuelle Urol. 2015 Jul;46(4):288-290 Authors: PMID: 26227127 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Krankenhausentgeltgesetz - Ein Honorararzt ist kein Wahlarzt.
Authors: PMID: 26227128 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Uroonkologie auf einen klick.
UROONKOLOGIE AUF EINEN KLICK. Aktuelle Urol. 2015 Jul;46(4):292 Authors: PMID: 26227129 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

[Percutaneous Stone Treatment Today: Standard-, Mini-, Micro-, Ultramini-PCNL].
Conclusion: Invasiveness of PCNL can be reduced with the nowadays available miniaturised systems. The indication for PCNL has been broadened to small kidney stones> 1 cm diameter. PMID: 26227130 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Authors: Wilhelm K, Fritsche HM, Netsch C, Für die AG „Endourologie und Urolithiasis“ der GeSRU Academics Tags: Aktuelle Urol Source Type: research

[Erectile Dysfunction in Diabetic Men].
Abstract Sexual functional dysfunctions represent a multidimensional nosological entity. Apart from the directly measurable pathophysiological parameters, psychological and dynamic partnership aspects are almost always involved. These can exert a triggering and a potentiating influence. Similarly, sociocultural factors have to be taken into account. In men the problem most frequently has a physiological focus and the main symptom within the complex of sexual difficulties, especially for diabetic patients, is erectile dysfunction. Disorders of ejaculation and orgasm may also occur. Testosterone production in men ma...
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Authors: Zitzmann M, Kliesch S Tags: Aktuelle Urol Source Type: research

[Scrotal Mass as a Rare Initial Manifestation of Necrotising Pancreatitis].
Abstract A scrotal mass as initial manifestation of necrotising pancreatitis is very rare. In addition, the diagnosis is very difficult because diseases that occur more frequently produce similar symptoms. Therefore, it is very important to think about rare entities in the differential diagnosis for testicular pain. PMID: 26227132 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Authors: Winkel A, Jakschik J, Kusche D Tags: Aktuelle Urol Source Type: research

Peniskarzinom - Operation des Primärtumors.
Peniskarzinom - Operation des Primärtumors. Aktuelle Urol. 2015 Jul;46(4):312-321 Authors: Protzel C, Hakenberg OW PMID: 26227133 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Authors: Protzel C, Hakenberg OW Tags: Aktuelle Urol Source Type: research

Geringinvasive Lymphknotendiagnostik und inguinale Lymphadenektomie.
PMID: 26227134 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 1, 2015 Category: Urology & Nephrology Authors: Protzel C, Hakenberg OW Tags: Aktuelle Urol Source Type: research

[In Process Citation].
PMID: 26077289 [PubMed - in process] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - May 1, 2015 Category: Urology & Nephrology Authors: Burger M Tags: Aktuelle Urol Source Type: research

[In Process Citation].
Authors: PMID: 26077290 [PubMed - in process] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - May 1, 2015 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research