Assessing the applications and efficacy of using helminthophagous fungi to control canine gastrointestinal parasites
Acta Trop. 2024 Mar 16:107180. doi: 10.1016/j.actatropica.2024.107180. Online ahead of print.ABSTRACTHelminths are a major challenge in dog breeding, particularly affecting young animals and posing a significant zoonotic risk. The widespread use of anthelmintics to treat gastrointestinal helminth infections in companion animals is common. However, these chemical products generate residues that can have adverse effects on animal, human and environmental health. In addition to the challenge of parasite resistance to treatment, there is an urgent need to explore and discuss complementary and sustainable methods of controlling...
Source: Acta Tropica - March 18, 2024 Category: Infectious Diseases Authors: J úlia Dos Santos Fonseca Helbert Ananias Valverde Beatriz Bacelar Barbosa Huarrisson Azevedo Santos Jackson Victor de Ara újo Source Type: research

Assessing the applications and efficacy of using helminthophagous fungi to control canine gastrointestinal parasites
Acta Trop. 2024 Mar 16:107180. doi: 10.1016/j.actatropica.2024.107180. Online ahead of print.ABSTRACTHelminths are a major challenge in dog breeding, particularly affecting young animals and posing a significant zoonotic risk. The widespread use of anthelmintics to treat gastrointestinal helminth infections in companion animals is common. However, these chemical products generate residues that can have adverse effects on animal, human and environmental health. In addition to the challenge of parasite resistance to treatment, there is an urgent need to explore and discuss complementary and sustainable methods of controlling...
Source: Acta Tropica - March 18, 2024 Category: Infectious Diseases Authors: J úlia Dos Santos Fonseca Helbert Ananias Valverde Beatriz Bacelar Barbosa Huarrisson Azevedo Santos Jackson Victor de Ara újo Source Type: research

Prophylactic activity of orally administered dry-heat-sterilized Acremonium egyptiacum against Trypanosoma congolense-induced animal African trypanosomosis
Acta Trop. 2024 Mar 15:107185. doi: 10.1016/j.actatropica.2024.107185. Online ahead of print.ABSTRACTAnimal African trypanosomosis (AAT) is an important global disease of livestock that causes economic losses of up to 4.5 billion US dollars per year. Thus, eliminating AAT in endemic countries will improve agricultural productivity and economic growth. To prevent AAT, vector control and the development of prophylactic drugs are crucial. Ascofuranone (AF) is a bioactive fungal compound with proven in vitro trypanocidal potency and in vivo treatment efficacy. However, the complex stereoselective synthesis of AF has prevented ...
Source: Acta Tropica - March 17, 2024 Category: Infectious Diseases Authors: Ai Yamazaki Yusuke Tanaka Kenichi Watanabe Mayu Sato Shin-Ichiro Kawazu Kiyoshi Kita Noboru Inoue Helena D Janse van Rensburg David D N'Da Keisuke Suganuma Source Type: research

The global prevalence of Cyclospora cayetanensis infection: A systematic review, meta-analysis, and meta-regression
Acta Trop. 2024 Mar 14:107175. doi: 10.1016/j.actatropica.2024.107175. Online ahead of print.ABSTRACTCyclospora cayetanensis (C. cayetanensis) is a significant pathogen that causes diarrheal illness and causes large foodborne diarrhea outbreaks in the USA and Canada. However, there is currently a lack of published meta-analysis on the prevalence of C. cayetanensis infection in the global population. A real estimation of a disease prevalence should always be done on the basis of studies designed for that purpose. We conducted a comprehensive search of various databases for articles pertaining to the prevalence of C. cayetan...
Source: Acta Tropica - March 16, 2024 Category: Infectious Diseases Authors: Yuancai Chen Ziyang Qin Junqiang Li Lihua Xiao Longxian Zhang Source Type: research

The global prevalence of Cyclospora cayetanensis infection: A systematic review, meta-analysis, and meta-regression
Acta Trop. 2024 Mar 14:107175. doi: 10.1016/j.actatropica.2024.107175. Online ahead of print.ABSTRACTCyclospora cayetanensis (C. cayetanensis) is a significant pathogen that causes diarrheal illness and causes large foodborne diarrhea outbreaks in the USA and Canada. However, there is currently a lack of published meta-analysis on the prevalence of C. cayetanensis infection in the global population. A real estimation of a disease prevalence should always be done on the basis of studies designed for that purpose. We conducted a comprehensive search of various databases for articles pertaining to the prevalence of C. cayetan...
Source: Acta Tropica - March 16, 2024 Category: Infectious Diseases Authors: Yuancai Chen Ziyang Qin Junqiang Li Lihua Xiao Longxian Zhang Source Type: research

Molecular Survey of Feline Immunodeficiency Virus (FIV) Infection in Namibian Cats
In this study, 279 blood samples from domestic cats in Namibia were analyzed for FIV diagnosis by PCR. The cats represented various regions and were cared for by people largely from rural areas with limited financial means. Only 1.43% of the samples tested positive, unexpectedly low given their outdoor lifestyles. The infected cats, primarily adult and unsterilized, showed no typical FIV symptoms, suggesting subclinical infections. Genetic analysis of the detected strains indicated a unique FIV strain cluster in Namibia, although with a certain within-country variability, in the absence of consistent geographical clusterin...
Source: Acta Tropica - March 13, 2024 Category: Infectious Diseases Authors: Giovanni Franzo Lourens de Villiers Lauren M Coetzee Mari de Villiers Umberto Molini Source Type: research

Diversity and genetic characterization of Chlamydia isolated from Siamese crocodiles (Crocodylus siamensis)
This study presents a whole-genome-based characterization of Siamese crocodile-isolated Chlamydia. The results showed that Siamese crocodile Chlamydia contained a single circular chromosome with a size of 1.22-1.23 Mbp and a plasmid with a size of 7.7-8.0 kbp. A plasmid containing eight coding sequences (CDSs) was grouped in a β lineage. A chromosome sequence had approximately 1,018-1,031 CDSs. Chlamydial factors involving virulence were documented in terms of the presence of cytotoxins and several virulence factors in the chromosomes of Siamese crocodile Chlamydia. The analysis of antimicrobial resistance genes in the Ch...
Source: Acta Tropica - March 13, 2024 Category: Infectious Diseases Authors: Somjit Chaiwattanarungruengpaisan Metawee Thongdee Nlin Arya Weena Paungpin Wanna Sirimanapong Ladawan Sariya Source Type: research

A Prospects Tool in Virus Research: Analyzing the Applications of Organoids in Virus Studies
This article reviews recent progress in the development of organoid and advancements in virus research. The potential applications of these models in studying virul infections, pathogenesis, and antiviral drug discovery are discussed.PMID:38479469 | DOI:10.1016/j.actatropica.2024.107182 (Source: Acta Tropica)
Source: Acta Tropica - March 13, 2024 Category: Infectious Diseases Authors: Qi Shen Yu-Han Zhou Yan-Qiu Zhou Source Type: research

Molecular Survey of Feline Immunodeficiency Virus (FIV) Infection in Namibian Cats
In this study, 279 blood samples from domestic cats in Namibia were analyzed for FIV diagnosis by PCR. The cats represented various regions and were cared for by people largely from rural areas with limited financial means. Only 1.43% of the samples tested positive, unexpectedly low given their outdoor lifestyles. The infected cats, primarily adult and unsterilized, showed no typical FIV symptoms, suggesting subclinical infections. Genetic analysis of the detected strains indicated a unique FIV strain cluster in Namibia, although with a certain within-country variability, in the absence of consistent geographical clusterin...
Source: Acta Tropica - March 13, 2024 Category: Infectious Diseases Authors: Giovanni Franzo Lourens de Villiers Lauren M Coetzee Mari de Villiers Umberto Molini Source Type: research

Diversity and genetic characterization of Chlamydia isolated from Siamese crocodiles (Crocodylus siamensis)
This study presents a whole-genome-based characterization of Siamese crocodile-isolated Chlamydia. The results showed that Siamese crocodile Chlamydia contained a single circular chromosome with a size of 1.22-1.23 Mbp and a plasmid with a size of 7.7-8.0 kbp. A plasmid containing eight coding sequences (CDSs) was grouped in a β lineage. A chromosome sequence had approximately 1,018-1,031 CDSs. Chlamydial factors involving virulence were documented in terms of the presence of cytotoxins and several virulence factors in the chromosomes of Siamese crocodile Chlamydia. The analysis of antimicrobial resistance genes in the Ch...
Source: Acta Tropica - March 13, 2024 Category: Infectious Diseases Authors: Somjit Chaiwattanarungruengpaisan Metawee Thongdee Nlin Arya Weena Paungpin Wanna Sirimanapong Ladawan Sariya Source Type: research

A Prospects Tool in Virus Research: Analyzing the Applications of Organoids in Virus Studies
This article reviews recent progress in the development of organoid and advancements in virus research. The potential applications of these models in studying virul infections, pathogenesis, and antiviral drug discovery are discussed.PMID:38479469 | DOI:10.1016/j.actatropica.2024.107182 (Source: Acta Tropica)
Source: Acta Tropica - March 13, 2024 Category: Infectious Diseases Authors: Qi Shen Yu-Han Zhou Yan-Qiu Zhou Source Type: research

Molecular Survey of Feline Immunodeficiency Virus (FIV) Infection in Namibian Cats
In this study, 279 blood samples from domestic cats in Namibia were analyzed for FIV diagnosis by PCR. The cats represented various regions and were cared for by people largely from rural areas with limited financial means. Only 1.43% of the samples tested positive, unexpectedly low given their outdoor lifestyles. The infected cats, primarily adult and unsterilized, showed no typical FIV symptoms, suggesting subclinical infections. Genetic analysis of the detected strains indicated a unique FIV strain cluster in Namibia, although with a certain within-country variability, in the absence of consistent geographical clusterin...
Source: Acta Tropica - March 13, 2024 Category: Infectious Diseases Authors: Giovanni Franzo Lourens de Villiers Lauren M Coetzee Mari de Villiers Umberto Molini Source Type: research

Diversity and genetic characterization of Chlamydia isolated from Siamese crocodiles (Crocodylus siamensis)
This study presents a whole-genome-based characterization of Siamese crocodile-isolated Chlamydia. The results showed that Siamese crocodile Chlamydia contained a single circular chromosome with a size of 1.22-1.23 Mbp and a plasmid with a size of 7.7-8.0 kbp. A plasmid containing eight coding sequences (CDSs) was grouped in a β lineage. A chromosome sequence had approximately 1,018-1,031 CDSs. Chlamydial factors involving virulence were documented in terms of the presence of cytotoxins and several virulence factors in the chromosomes of Siamese crocodile Chlamydia. The analysis of antimicrobial resistance genes in the Ch...
Source: Acta Tropica - March 13, 2024 Category: Infectious Diseases Authors: Somjit Chaiwattanarungruengpaisan Metawee Thongdee Nlin Arya Weena Paungpin Wanna Sirimanapong Ladawan Sariya Source Type: research

A Prospects Tool in Virus Research: Analyzing the Applications of Organoids in Virus Studies
This article reviews recent progress in the development of organoid and advancements in virus research. The potential applications of these models in studying virul infections, pathogenesis, and antiviral drug discovery are discussed.PMID:38479469 | DOI:10.1016/j.actatropica.2024.107182 (Source: Acta Tropica)
Source: Acta Tropica - March 13, 2024 Category: Infectious Diseases Authors: Qi Shen Yu-Han Zhou Yan-Qiu Zhou Source Type: research

Spatial analysis of food and water-borne diseases in Ahmedabad, India: Implications for urban public health planning
Acta Trop. 2024 Mar 11;253:107170. doi: 10.1016/j.actatropica.2024.107170. Online ahead of print.ABSTRACTSpatial analysis of infectious diseases can play an important role in mapping the spread of diseases and can support policy making at local level. Moreover, identification of disease clusters based on local geography and landscape forms the basis for disease control and prevention. Therefore, this study aimed to examine the spatial-temporal variations, hotspot areas, and potential risk factors of infectious diseases (including Viral Hepatitis, Typhoid and Diarrhea) in Ahmedabad city of India. We used Moran's I and Local...
Source: Acta Tropica - March 11, 2024 Category: Infectious Diseases Authors: Ayushi Sharma Bima Sakti Satria Wibawa Gerry Andhikaputra Bhavin Solanki Amir Sapkota Lin-Han Chiang Hsieh Veena Iyer Yu-Chun Wang Source Type: research