[ASAP] Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01093 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 20, 2018 Category: Chemistry Authors: Anastasia Amato, Xavier Lucas, Alessio Bortoluzzi, David Wright, Alessio Ciulli Source Type: research

Targeting of G-Quadruplex Harboring Pre-miRNA 92b by LNA Rescues PTEN Expression in NSCL Cancer Cells
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00749 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 19, 2018 Category: Chemistry Authors: Gayan Mirihana Arachchilage, Prakash Kharel, Joshua Reid and Soumitra Basu Source Type: research

A High Content Screen in Macrophages Identifies Small Molecule Modulators of STING-IRF3 and NFkB Signaling
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01060 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 19, 2018 Category: Chemistry Authors: Peter D. Koch, Howard R. Miller, Gary Yu, John A. Tallarico, Peter K. Sorger, Yuan Wang, Yan Feng, Jason R. Thomas, Nathan T. Ross and Timothy Mitchison Source Type: research

[ASAP] A High Content Screen in Macrophages Identifies Small Molecule Modulators of STING-IRF3 and NFkB Signaling
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01060 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 19, 2018 Category: Chemistry Authors: Peter D. Koch, Howard R. Miller, Gary Yu, John A. Tallarico, Peter K. Sorger, Yuan Wang, Yan Feng, Jason R. Thomas, Nathan T. Ross, Timothy Mitchison Source Type: research

[ASAP] Targeting of G-Quadruplex Harboring Pre-miRNA 92b by LNA Rescues PTEN Expression in NSCL Cancer Cells
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00749 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 19, 2018 Category: Chemistry Authors: Gayan Mirihana Arachchilage, Prakash Kharel, Joshua Reid, Soumitra Basu Source Type: research

Photochemical Control of Protein Arginine Deiminase (PAD) Activity
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00053 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 16, 2018 Category: Chemistry Authors: Santanu Mondal, Sangram S. Parelkar, Mitesh Nagar and Paul R. Thompson Source Type: research

Reading between the Lines: “ADD”-ing Histone and DNA Methylation Marks toward a New Epigenetic “Sum”
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00162 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 16, 2018 Category: Chemistry Authors: K. M. Noh, C. D. Allis and H. Li Source Type: research

[ASAP] Reading between the Lines: “ADD”-ing Histone and DNA Methylation Marks toward a New Epigenetic “Sum”
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00162 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 16, 2018 Category: Chemistry Authors: K. M. Noh, C. D. Allis, H. Li Source Type: research

[ASAP] Photochemical Control of Protein Arginine Deiminase (PAD) Activity
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00053 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 16, 2018 Category: Chemistry Authors: Santanu Mondal, Sangram S. Parelkar, Mitesh Nagar, Paul R. Thompson Source Type: research

DNA Polymerase θ Increases Mutational Rates in Mitochondrial DNA
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00072 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 15, 2018 Category: Chemistry Authors: Simon Wisnovsky, Tanja Sack, David J. Pagliarini, Rebecca R. Laposa and Shana O. Kelley Source Type: research

[ASAP] DNA Polymerase ? Increases Mutational Rates in Mitochondrial DNA
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00072 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 15, 2018 Category: Chemistry Authors: Simon Wisnovsky, Tanja Sack, David J. Pagliarini, Rebecca R. Laposa, Shana O. Kelley Source Type: research

Functionally Biased D2R Antagonists: Targeting the β-Arrestin Pathway to Improve Antipsychotic Treatment
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00168 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 14, 2018 Category: Chemistry Authors: Michel Wei ̈wer, Qihong Xu, Jennifer P. Gale, Michael Lewis, Arthur J. Campbell, Frederick A. Schroeder, Genevieve C. Van de Bittner, Michelle Walk, Aldo Amaya, Ping Su, Luka D̵ordevic, Joshua R. Sacher, Adam Skepner, David Fei, Kelly Dennehy, Shannon N Source Type: research

Acyl-CoA Oxidases Fine-Tune the Production of Ascaroside Pheromones with Specific Side Chain Lengths
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01021 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 14, 2018 Category: Chemistry Authors: Xinxing Zhang, Yuting Wang, David H. Perez, Rachel A. Jones Lipinski and Rebecca A. Butcher Source Type: research

[ASAP] Functionally Biased D2R Antagonists: Targeting the ß-Arrestin Pathway to Improve Antipsychotic Treatment
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00168 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 14, 2018 Category: Chemistry Authors: Michel We ïwer, Qihong Xu, Jennifer P. Gale, Michael Lewis, Arthur J. Campbell, Frederick A. Schroeder, Genevieve C. Van de Bittner, Michelle Walk, Aldo Amaya, Ping Su, Luka D?ordevic, Joshua R. Sacher, Adam Skepner, David Fei, Kelly Dennehy, Shannon Ngu Source Type: research

[ASAP] Acyl-CoA Oxidases Fine-Tune the Production of Ascaroside Pheromones with Specific Side Chain Lengths
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01021 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 14, 2018 Category: Chemistry Authors: Xinxing Zhang, Yuting Wang, David H. Perez, Rachel A. Jones Lipinski, Rebecca A. Butcher Source Type: research

Determination of the Subcellular Localization and Mechanism of Action of Ferrostatins in Suppressing Ferroptosis
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00199 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 13, 2018 Category: Chemistry Authors: Michael M. Gaschler, Fanghao Hu, Huizhong Feng, Andreas Linkermann, Wei Min and Brent R. Stockwell Source Type: research

Discovery of the Tyrobetaine Natural Products and Their Biosynthetic Gene Cluster via Metabologenomics
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01089 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 13, 2018 Category: Chemistry Authors: Elizabeth I. Parkinson, James H. Tryon, Anthony W. Goering, Kou-San Ju, Ryan A. McClure, Jeremy D. Kemball, Sara Zhukovsky, David P. Labeda, Regan J. Thomson, Neil L. Kelleher and William W. Metcalf Source Type: research

Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00026 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 13, 2018 Category: Chemistry Authors: Yogan Khatri, Ilona K. Jo ́źwik, Michael Ringle, Irina Alexandra Ionescu, Martin Litzenburger, Michael Christopher Hutter, Andy-Mark W. H. Thunnissen and Rita Bernhardt Source Type: research

[ASAP] Determination of the Subcellular Localization and Mechanism of Action of Ferrostatins in Suppressing Ferroptosis
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00199 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 13, 2018 Category: Chemistry Authors: Michael M. Gaschler, Fanghao Hu, Huizhong Feng, Andreas Linkermann, Wei Min, Brent R. Stockwell Source Type: research

[ASAP] Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00026 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 13, 2018 Category: Chemistry Authors: Yogan Khatri, Ilona K. J ózwik, Michael Ringle, Irina Alexandra Ionescu, Martin Litzenburger, Michael Christopher Hutter, Andy-Mark W. H. Thunnissen, Rita Bernhardt Source Type: research

[ASAP] Discovery of the Tyrobetaine Natural Products and Their Biosynthetic Gene Cluster < italic toggle="yes" > via < /italic > Metabologenomics
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01089 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 13, 2018 Category: Chemistry Authors: Elizabeth I. Parkinson, James H. Tryon, Anthony W. Goering, Kou-San Ju, Ryan A. McClure, Jeremy D. Kemball, Sara Zhukovsky, David P. Labeda, Regan J. Thomson, Neil L. Kelleher, William W. Metcalf Source Type: research

Functional and Structural Analysis of Phenazine O-Methyltransferase LaPhzM from Lysobacter antibioticus OH13 and One-Pot Enzymatic Synthesis of the Antibiotic Myxin
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00062 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 12, 2018 Category: Chemistry Authors: Jiasong Jiang, Daisy Guiza Beltran, Andrew Schacht, Stephen Wright, Limei Zhang and Liangcheng Du Source Type: research

[ASAP] Functional and Structural Analysis of Phenazine < italic toggle="yes" > O < /italic > -Methyltransferase LaPhzM from < italic toggle="yes" > Lysobacter antibioticus < /italic > OH13 and One-Pot Enzymatic Synthesis of the Antibiotic Myxin
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00062 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 12, 2018 Category: Chemistry Authors: Jiasong Jiang, Daisy Guiza Beltran, Andrew Schacht, Stephen Wright, Limei Zhang, Liangcheng Du Source Type: research

Photophysical Tuning of N-Oxide-Based Probes Enables Ratiometric Photoacoustic Imaging of Tumor Hypoxia
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00099 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 9, 2018 Category: Chemistry Authors: Hailey J. Knox, Tae Wook Kim, Zhouyang Zhu and Jefferson Chan Source Type: research

Bioluminescent Low-Affinity Ca2+ Indicator for ER with Multicolor Calcium Imaging in Single Living Cells
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01014 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 9, 2018 Category: Chemistry Authors: Md Nadim Hossain, Kazushi Suzuki, Megumi Iwano, Tomoki Matsuda and Takeharu Nagai Source Type: research

Quorum Sensing Signals Form Complexes with Ag+ and Cu2+ Cations
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01000 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 9, 2018 Category: Chemistry Authors: Eric McGivney, Kayleigh Elizabeth Jones, Bandrea Weber, Ann Margaret Valentine, Jeanne M. VanBriesen and Kelvin B. Gregory Source Type: research

[ASAP] Photophysical Tuning of < italic toggle="yes" > N < /italic > -Oxide-Based Probes Enables Ratiometric Photoacoustic Imaging of Tumor Hypoxia
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00099 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 9, 2018 Category: Chemistry Authors: Hailey J. Knox, Tae Wook Kim, Zhouyang Zhu, Jefferson Chan Source Type: research

[ASAP] Bioluminescent Low-Affinity Ca < sup > 2+ < /sup > Indicator for ER with Multicolor Calcium Imaging in Single Living Cells
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01014 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 9, 2018 Category: Chemistry Authors: Md Nadim Hossain, Kazushi Suzuki, Megumi Iwano, Tomoki Matsuda, Takeharu Nagai Source Type: research

[ASAP] Quorum Sensing Signals Form Complexes with Ag < sup > + < /sup > and Cu < sup > 2+ < /sup > Cations
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01000 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 9, 2018 Category: Chemistry Authors: Eric McGivney, Kayleigh Elizabeth Jones, Bandrea Weber, Ann Margaret Valentine, Jeanne M. VanBriesen, Kelvin B. Gregory Source Type: research

Chemiluminescent Biosensors for Detection of Second Messenger Cyclic di-GMP
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01019 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 5, 2018 Category: Chemistry Authors: Andrew B. Dippel, Wyatt A. Anderson, Robert S. Evans, Samuel Deutsch and Ming C. Hammond Source Type: research

Reversibly Switchable, pH-Dependent Peptide Ligand Binding via 3,5-Diiodotyrosine Substitutions
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00171 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 5, 2018 Category: Chemistry Authors: Chayanon Ngambenjawong, Meilyn Sylvestre, Heather H. Gustafson, Julio Marco B. Pineda and Suzie H. Pun Source Type: research

[ASAP] Reversibly Switchable, pH-Dependent Peptide Ligand Binding via 3,5-Diiodotyrosine Substitutions
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00171 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 5, 2018 Category: Chemistry Authors: Chayanon Ngambenjawong, Meilyn Sylvestre, Heather H. Gustafson, Julio Marco B. Pineda, Suzie H. Pun Source Type: research

[ASAP] Chemiluminescent Biosensors for Detection of Second Messenger Cyclic di-GMP
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01019 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 5, 2018 Category: Chemistry Authors: Andrew B. Dippel, Wyatt A. Anderson, Robert S. Evans, Samuel Deutsch, Ming C. Hammond Source Type: research

Playing with the Molecules of Life
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00974 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 2, 2018 Category: Chemistry Authors: Douglas D. Young and Peter G. Schultz Source Type: research

[ASAP] Playing with the Molecules of Life
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00974 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 2, 2018 Category: Chemistry Authors: Douglas D. Young, Peter G. Schultz Source Type: research

Structural and Functional Studies of a Pyran Synthase Domain from a trans-Acyltransferase Assembly Line
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00049 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 1, 2018 Category: Chemistry Authors: Drew T. Wagner, Zhicheng Zhang, Roy A. Meoded, Alexis J. Cepeda, Jo ̈rn Piel and Adrian T. Keatinge-Clay Source Type: research

Combined Chemical Synthesis and Tailored Enzymatic Elongation Provide Fully Synthetic and Conjugation-Ready Neisseria meningitidis Serogroup X Vaccine Antigens
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01057 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 1, 2018 Category: Chemistry Authors: Davide Oldrini, Timm Fiebig, Maria Rosaria Romano, Daniela Proietti, Monika Berger, Marta Tontini, Riccardo De Ricco, Laura Santini, Laura Morelli, Luigi Lay, Rita Gerardy-Schahn, Francesco Berti and Roberto Adamo Source Type: research

Identification of Protein Targets of 12/15-Lipoxygenase-Derived Lipid Electrophiles in Mouse Peritoneal Macrophages Using Omega-Alkynyl Fatty Acid
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01092 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 1, 2018 Category: Chemistry Authors: Yosuke Isobe, Yusuke Kawashima, Tomoaki Ishihara, Kenji Watanabe, Osamu Ohara and Makoto Arita Source Type: research

[ASAP] Structural and Functional Studies of a Pyran Synthase Domain from a < italic > trans < /italic > -Acyltransferase Assembly Line
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00049 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 1, 2018 Category: Chemistry Authors: Drew T. Wagner, Zhicheng Zhang, Roy A. Meoded, Alexis J. Cepeda, J örn Piel, Adrian T. Keatinge-Clay Source Type: research

[ASAP] Identification of Protein Targets of 12/15-Lipoxygenase-Derived Lipid Electrophiles in Mouse Peritoneal Macrophages Using Omega-Alkynyl Fatty Acid
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01092 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 1, 2018 Category: Chemistry Authors: Yosuke Isobe, Yusuke Kawashima, Tomoaki Ishihara, Kenji Watanabe, Osamu Ohara, Makoto Arita Source Type: research

[ASAP] Combined Chemical Synthesis and Tailored Enzymatic Elongation Provide Fully Synthetic and Conjugation-Ready < italic > Neisseria meningitidis < /italic > Serogroup X Vaccine Antigens
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01057 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - March 1, 2018 Category: Chemistry Authors: Davide Oldrini, Timm Fiebig, Maria Rosaria Romano, Daniela Proietti, Monika Berger, Marta Tontini, Riccardo De Ricco, Laura Santini, Laura Morelli, Luigi Lay, Rita Gerardy-Schahn, Francesco Berti, Roberto Adamo Source Type: research

Snapshots of the Catalytic Cycle of an O2, Pyridoxal Phosphate-Dependent Hydroxylase
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00039 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 28, 2018 Category: Chemistry Authors: Jason B. Hedges, Eugene Kuatsjah, Yi-Ling Du, Lindsay D. Eltis and Katherine S. Ryan Source Type: research

A Switchable Site-Specific Antibody Conjugate
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00107 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 28, 2018 Category: Chemistry Authors: Zhigang Lyu, Lei Kang, Zakey Yusuf Buuh, Dawei Jiang, Jeffrey C. McGuth, Juanjuan Du, Haley L. Wissler, Weibo Cai and Rongsheng E. Wang Source Type: research

[ASAP] A Switchable Site-Specific Antibody Conjugate
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00107 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 28, 2018 Category: Chemistry Authors: Zhigang Lyu, Lei Kang, Zakey Yusuf Buuh, Dawei Jiang, Jeffrey C. McGuth, Juanjuan Du, Haley L. Wissler, Weibo Cai, Rongsheng E. Wang Source Type: research

[ASAP] Snapshots of the Catalytic Cycle of an O < sub > 2 < /sub > , Pyridoxal Phosphate-Dependent Hydroxylase
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00039 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 28, 2018 Category: Chemistry Authors: Jason B. Hedges, Eugene Kuatsjah, Yi-Ling Du, Lindsay D. Eltis, Katherine S. Ryan Source Type: research

Ligand-Directed Chemistry of AMPA Receptors Confers Live-Cell Fluorescent Biosensors
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01042 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 27, 2018 Category: Chemistry Authors: Shigeki Kiyonaka, Seiji Sakamoto, Sho Wakayama, Yuma Morikawa, Muneo Tsujikawa and Itaru Hamachi Source Type: research

Inhibition of HIV Fusion by Small Molecule Agonists through Efficacy-Engineering of CXCR4
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00061 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 27, 2018 Category: Chemistry Authors: Christian Berg, Viktorija Daugvilaite, Anne Steen, Astrid Sissel J ørgensen, Jon Våbenø and Mette Marie Rosenkilde Source Type: research

[ASAP] Inhibition of HIV Fusion by Small Molecule Agonists through Efficacy-Engineering of CXCR4
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00061 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 27, 2018 Category: Chemistry Authors: Christian Berg, Viktorija Daugvilaite, Anne Steen, Astrid Sissel J ørgensen, Jon Våbenø, Mette Marie Rosenkilde Source Type: research

[ASAP] Ligand-Directed Chemistry of AMPA Receptors Confers Live-Cell Fluorescent Biosensors
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01042 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 27, 2018 Category: Chemistry Authors: Shigeki Kiyonaka, Seiji Sakamoto, Sho Wakayama, Yuma Morikawa, Muneo Tsujikawa, Itaru Hamachi Source Type: research

Biogenesis of Asparagine-Linked Glycoproteins Across Domains of Life Similarities and Differences
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00163 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 26, 2018 Category: Chemistry Authors: Jerry Eichler and Barbara Imperiali Source Type: research