Ligand-Directed Chemistry of AMPA Receptors Confers Live-Cell Fluorescent Biosensors
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01042 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 27, 2018 Category: Chemistry Authors: Shigeki Kiyonaka, Seiji Sakamoto, Sho Wakayama, Yuma Morikawa, Muneo Tsujikawa and Itaru Hamachi Source Type: research

Inhibition of HIV Fusion by Small Molecule Agonists through Efficacy-Engineering of CXCR4
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00061 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 27, 2018 Category: Chemistry Authors: Christian Berg, Viktorija Daugvilaite, Anne Steen, Astrid Sissel J ørgensen, Jon Våbenø and Mette Marie Rosenkilde Source Type: research

[ASAP] Inhibition of HIV Fusion by Small Molecule Agonists through Efficacy-Engineering of CXCR4
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00061 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 27, 2018 Category: Chemistry Authors: Christian Berg, Viktorija Daugvilaite, Anne Steen, Astrid Sissel J ørgensen, Jon Våbenø, Mette Marie Rosenkilde Source Type: research

[ASAP] Ligand-Directed Chemistry of AMPA Receptors Confers Live-Cell Fluorescent Biosensors
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01042 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 27, 2018 Category: Chemistry Authors: Shigeki Kiyonaka, Seiji Sakamoto, Sho Wakayama, Yuma Morikawa, Muneo Tsujikawa, Itaru Hamachi Source Type: research

Biogenesis of Asparagine-Linked Glycoproteins Across Domains of Life Similarities and Differences
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00163 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 26, 2018 Category: Chemistry Authors: Jerry Eichler and Barbara Imperiali Source Type: research

[ASAP] Biogenesis of Asparagine-Linked Glycoproteins Across Domains of Life —Similarities and Differences
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00163 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 26, 2018 Category: Chemistry Authors: Jerry Eichler, Barbara Imperiali Source Type: research

Incorporation of Nonproteinogenic Amino Acids in Class I and II Lantibiotics
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01024 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 21, 2018 Category: Chemistry Authors: Nidhi Kakkar, Jessica G. Perez, Wenshe R. Liu, Michael C. Jewett and Wilfred A. van der Donk Source Type: research

In Situ Target Engagement Studies in Adherent Cells
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01079 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 21, 2018 Category: Chemistry Authors: Hanna Axelsson, Helena Almqvist, Magdalena Otrocka, Michaela Vallin, Sara Lundqvist, Pia Hansson, Ulla Karlsson, Thomas Lundba ̈ck and Brinton Seashore-Ludlow Source Type: research

[ASAP] < italic toggle="yes" > In Situ < /italic > Target Engagement Studies in Adherent Cells
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01079 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 21, 2018 Category: Chemistry Authors: Hanna Axelsson, Helena Almqvist, Magdalena Otrocka, Michaela Vallin, Sara Lundqvist, Pia Hansson, Ulla Karlsson, Thomas Lundb äck, Brinton Seashore-Ludlow Source Type: research

[ASAP] < italic > In Situ < /italic > Target Engagement Studies in Adherent Cells
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01079 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 21, 2018 Category: Chemistry Authors: Hanna Axelsson, Helena Almqvist, Magdalena Otrocka, Michaela Vallin, Sara Lundqvist, Pia Hansson, Ulla Karlsson, Thomas Lundb äck, Brinton Seashore-Ludlow Source Type: research

[ASAP] Incorporation of Nonproteinogenic Amino Acids in Class I and II Lantibiotics
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01024 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 21, 2018 Category: Chemistry Authors: Nidhi Kakkar, Jessica G. Perez, Wenshe R. Liu, Michael C. Jewett, Wilfred A. van der Donk Source Type: research

More Than a Light Switch: Engineering Unconventional Fluorescent Configurations for Biological Sensing
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01022 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 20, 2018 Category: Chemistry Authors: William J. Peveler and W. Russ Algar Source Type: research

Trifunctional High-Throughput Screen Identifies Promising Scaffold To Inhibit Grp94 and Treat Myocilin-Associated Glaucoma
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01083 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 20, 2018 Category: Chemistry Authors: Dustin J. E. Huard, Vincent M. Crowley, Yuhong Du, Ricardo A. Cordova, Zheying Sun, Moya O. Tomlin, Chad A. Dickey, John Koren, Laura Blair, Haian Fu, Brian S. J. Blagg and Raquel L. Lieberman Source Type: research

[ASAP] Trifunctional High-Throughput Screen Identifies Promising Scaffold To Inhibit Grp94 and Treat Myocilin-Associated Glaucoma
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01083 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 20, 2018 Category: Chemistry Authors: Dustin J. E. Huard, Vincent M. Crowley, Yuhong Du, Ricardo A. Cordova, Zheying Sun, Moya O. Tomlin, Chad A. Dickey, John Koren , III, Laura Blair, Haian Fu, Brian S. J. Blagg, Raquel L. Lieberman Source Type: research

[ASAP] More Than a Light Switch: Engineering Unconventional Fluorescent Configurations for Biological Sensing
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01022 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 20, 2018 Category: Chemistry Authors: William J. Peveler, W. Russ Algar Source Type: research

Thienyl-Substituted α-Ketoamide: A Less Hydrophobic Reactive Group for Photo-Affinity Labeling
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00988 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 19, 2018 Category: Chemistry Authors: Eisuke Ota, Kazuteru Usui, Kana Oonuma, Hiroyuki Koshino, Shigeru Nishiyama, Go Hirai and Mikiko Sodeoka Source Type: research

Lessons Learned from Luminous Luciferins and Latent Luciferases
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00964 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 19, 2018 Category: Chemistry Authors: Stephen C. Miller, David M. Mofford and Spencer T. Adams Source Type: research

[ASAP] Thienyl-Substituted a-Ketoamide: A Less Hydrophobic Reactive Group for Photo-Affinity Labeling
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00988 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 19, 2018 Category: Chemistry Authors: Eisuke Ota, Kazuteru Usui, Kana Oonuma, Hiroyuki Koshino, Shigeru Nishiyama, Go Hirai, Mikiko Sodeoka Source Type: research

[ASAP] Lessons Learned from Luminous Luciferins and Latent Luciferases
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00964 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 19, 2018 Category: Chemistry Authors: Stephen C. Miller, David M. Mofford, Spencer T. Adams , Jr. Source Type: research

Smart Cell Culture Systems: Integration of Sensors and Actuators into Microphysiological Systems
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01029 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 15, 2018 Category: Chemistry Authors: Mario M. Modena, Ketki Chawla, Patrick M. Misun and Andreas Hierlemann Source Type: research

Stereospecificity of Enoylreductase Domains from Modular Polyketide Synthases
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00982 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 15, 2018 Category: Chemistry Authors: Luyun Zhang, Junjie Ji, Meijuan Yuan, Yuanyuan Feng, Lei Wang, Zixin Deng, Linquan Bai and Jianting Zheng Source Type: research

[ASAP] Smart Cell Culture Systems: Integration of Sensors and Actuators into Microphysiological Systems
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01029 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 15, 2018 Category: Chemistry Authors: Mario M. Modena, Ketki Chawla, Patrick M. Misun, Andreas Hierlemann Source Type: research

[ASAP] Stereospecificity of Enoylreductase Domains from Modular Polyketide Synthases
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00982 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 15, 2018 Category: Chemistry Authors: Luyun Zhang, Junjie Ji, Meijuan Yuan, Yuanyuan Feng, Lei Wang, Zixin Deng, Linquan Bai, Jianting Zheng Source Type: research

Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01013 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 14, 2018 Category: Chemistry Authors: Noreen F. Rizvi, John A. Howe, Ali Nahvi, Daniel J. Klein, Thierry O. Fischmann, Hai-Young Kim, Mark A. McCoy, Scott S. Walker, Alan Hruza, Matthew P. Richards, Chad Chamberlin, Peter Saradjian, Margaret T. Butko, Gabriel Mercado, Julja Burchard, Corey St Source Type: research

Human Neuraminidase Isoenzymes Show Variable Activities for 9-O-Acetyl-sialoside Substrates
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00952 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 13, 2018 Category: Chemistry Authors: Carmanah D. Hunter, Neha Khanna, Michele R. Richards, Reza Rezaei Darestani, Chunxia Zou, John S. Klassen and Christopher W. Cairo Source Type: research

Antimicrobial Metallopeptides
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00989 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 13, 2018 Category: Chemistry Authors: Jessica L. Alexander, Zechariah Thompson and J. A. Cowan Source Type: research

Biosynthesis of the Klebsiella oxytoca Pathogenicity Factor Tilivalline: Heterologous Expression, in Vitro Biosynthesis, and Inhibitor Development
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00990 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 13, 2018 Category: Chemistry Authors: Alexander von Tesmar, Michael Hoffmann, Antoine Abou Fayad, Stephan Hu ̈ttel, Viktoria Schmitt, Jennifer Herrmann and Rolf Müller Source Type: research

[ASAP] Antimicrobial Metallopeptides
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00989 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 13, 2018 Category: Chemistry Authors: Jessica L. Alexander, Zechariah Thompson, J. A. Cowan Source Type: research

[ASAP] Human Neuraminidase Isoenzymes Show Variable Activities for 9- < italic > O < /italic > -Acetyl-sialoside Substrates
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00952 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 13, 2018 Category: Chemistry Authors: Carmanah D. Hunter, Neha Khanna, Michele R. Richards, Reza Rezaei Darestani, Chunxia Zou, John S. Klassen, Christopher W. Cairo Source Type: research

Characterization of the Fast and Promiscuous Macrocyclase from Plant PCY1 Enables the Use of Simple Substrates
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00050 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 12, 2018 Category: Chemistry Authors: Hannes Ludewig, Clarissa M. Czekster, Emilia Oueis, Elizabeth S. Munday, Mohammed Arshad, Silvia A. Synowsky, Andrew F. Bent and James H. Naismith Source Type: research

Understanding the Molecular Mechanisms of the CRISPR Toolbox Using Single Molecule Approaches
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00905 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 9, 2018 Category: Chemistry Authors: Digvijay Singh and Taekjip Ha Source Type: research

A Predictive Approach for the Optical Control of Carbonic Anhydrase II Activity
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00862 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 9, 2018 Category: Chemistry Authors: Kateri H. DuBay, Katharina Iwan, Laura Osorio-Planes, Phillip L. Geissler, Michael Groll, Dirk Trauner and Johannes Broichhagen Source Type: research

Site-Specific Incorporation of a Thioester Containing Amino Acid into Proteins
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00998 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 9, 2018 Category: Chemistry Authors: Weimin Xuan, Daniel Collins, Minseob Koh, Sida Shao, Anzhi Yao, Han Xiao, Philip Garner and Peter G. Schultz Source Type: research

Development of Activity-Based Chemical Probes for Human Sirtuins
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00754 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 8, 2018 Category: Chemistry Authors: Elysian Graham, Stacia Rymarchyk, Marci Wood and Yana Cen Source Type: research

Toward a Microparticle-Based System for Pooled Assays of Small Molecules in Cellular Contexts
ACS Chemical BiologyDOI: 10.1021/acschembio.8b00043 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 8, 2018 Category: Chemistry Authors: Carrie E. Yozwiak, Tal Hirschhorn and Brent R. Stockwell Source Type: research

Design and Application of Sensors for Chemical Cytometry
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01009 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 8, 2018 Category: Chemistry Authors: Brianna M. Vickerman, Matthew M. Anttila, Brae V. Petersen, Nancy L. Allbritton and David S. Lawrence Source Type: research

Cardiovascular Small Heat Shock Protein HSPB7 Is a Kinetically Privileged Reactive Electrophilic Species (RES) Sensor
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00925 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 8, 2018 Category: Chemistry Authors: Sanjna L. Surya, Marcus J. C. Long, Daniel A. Urul, Yi Zhao, Emily J. Mercer, Islam M. EIsaid, Todd Evans and Yimon Aye Source Type: research

Light-Activated Proteomic Labeling via Photocaged Bioorthogonal Non-Canonical Amino Acids
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01023 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 8, 2018 Category: Chemistry Authors: Steven M. Adelmund, Emily R. Ruskowitz, Payam E. Farahani, Julie V. Wolfe and Cole A. DeForest Source Type: research

Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00890 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 8, 2018 Category: Chemistry Authors: Fei Ye, Xiangqian Kong, Hao Zhang, Yan Liu, Zhiyuan Shao, Jia Jin, Yi Cai, Rukang Zhang, Linjuan Li, Yang W. Zhang, Yu-Chih Liu, Chenhua Zhang, Wenbing Xie, Kunqian Yu, Hong Ding, Kehao Zhao, Shijie Chen, Hualiang Jiang, Stephen B. Baylin and Cheng Luo Source Type: research

[ASAP] Design and Application of Sensors for Chemical Cytometry
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01009 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 8, 2018 Category: Chemistry Authors: Brianna M. Vickerman, Matthew M. Anttila, Brae V. Petersen, Nancy L. Allbritton, David S. Lawrence Source Type: research

[ASAP] Cardiovascular Small Heat Shock Protein HSPB7 Is a Kinetically Privileged Reactive Electrophilic Species (RES) Sensor
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00925 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 8, 2018 Category: Chemistry Authors: Sanjna L. Surya, Marcus J. C. Long, Daniel A. Urul, Yi Zhao, Emily J. Mercer, Islam M. EIsaid, Todd Evans, Yimon Aye Source Type: research

Quantitative mRNA Imaging with Dual Channel qFIT Probes to Monitor Distribution and Degree of Hybridization
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01007 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 7, 2018 Category: Chemistry Authors: Imre Gaspar, Felix Ho ̈velmann, Jasmine Chamiolo, Anne Ephrussi and Oliver Seitz Source Type: research

Heme Binding to Porphobilinogen Deaminase from Vibrio cholerae Decelerates the Formation of 1-Hydroxymethylbilane
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00934 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 7, 2018 Category: Chemistry Authors: Takeshi Uchida, Takumi Funamizu, Minghao Chen, Yoshikazu Tanaka and Koichiro Ishimori Source Type: research

Can CRISPR-Based Gene Drive Be Confined in the Wild? A Question for Molecular and Population Biology
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00923 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 7, 2018 Category: Chemistry Authors: John M. Marshall and Omar S. Akbari Source Type: research

Turning the Spotlight on Lipids in Non-Apoptotic Cell Death
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01082 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 6, 2018 Category: Chemistry Authors: Laura R. Parisi, Lauren M. Morrow, Michelle B. Visser and G. Ekin Atilla-Gokcumen Source Type: research

The Effects of Ultraviolet Radiation on Nucleoside Modifications in RNA
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00898 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 5, 2018 Category: Chemistry Authors: Congliang Sun, Manasses Jora, Beulah Solivio, Patrick A. Limbach and Balasubrahmanyam Addepalli Source Type: research

Gene Drive: Evolved and Synthetic
ACS Chemical BiologyDOI: 10.1021/acschembio.7b01031 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 5, 2018 Category: Chemistry Authors: Austin Burt and Andrea Crisanti Source Type: research

Biosynthesis and Structure –Activity Relationship Studies of Okaramines That Target Insect Glutamate-Gated Chloride Channels
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00878 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 2, 2018 Category: Chemistry Authors: Naoki Kato, Shogo Furutani, Junnosuke Otaka, Akira Noguchi, Kiyomi Kinugasa, Kenji Kai, Hideo Hayashi, Makoto Ihara, Shunji Takahashi, Kazuhiko Matsuda and Hiroyuki Osada Source Type: research

A Cleavage-Responsive Stem-Loop Hairpin for Assaying Guide RNA Activity
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00899 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 2, 2018 Category: Chemistry Authors: Tara R. deBoer, Noreen Wauford, Jing-Yi Chung, Miguel Salvador Torres Perez and Niren Murthy Source Type: research

Fe(II) Ion Release during Endocytotic Uptake of Iron Visualized by a Membrane-Anchoring Fe(II) Fluorescent Probe
ACS Chemical BiologyDOI: 10.1021/acschembio.7b00939 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - February 2, 2018 Category: Chemistry Authors: Masato Niwa, Tasuku Hirayama, Ikumi Oomoto, Dan Ohtan Wang and Hideko Nagasawa Source Type: research