[ASAP] Novel Regioselective Approach to Cyclize Phage-Displayed Peptides in Combination with Epitope-Directed Selection to Identify a Potent Neutralizing Macrocyclic Peptide for SARS-CoV ‑2
ACS Chemical BiologyDOI: 10.1021/acschembio.2c00565 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - September 29, 2022 Category: Chemistry Authors: J. Trae Hampton, Tyler J. Lalonde, Jeffery M. Tharp, Yadagiri Kurra, Yugendar R. Alugubelli, Christopher M. Roundy, Gabriel L. Hamer, Shiqing Xu, and Wenshe Ray Liu Source Type: research

[ASAP] Probing the KRas Switch II Groove by Fluorine NMR Spectroscopy
ACS Chemical BiologyDOI: 10.1021/acschembio.2c00566 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - September 27, 2022 Category: Chemistry Authors: D. Matthew Peacock, Mark J. S. Kelly, and Kevan M. Shokat Source Type: research

[ASAP] Anchor Residues Govern Binding and Folding of an Intrinsically Disordered Domain
ACS Chemical BiologyDOI: 10.1021/acschembio.2c00619 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - September 26, 2022 Category: Chemistry Authors: Haley I. Merritt, Nicholas Sawyer, Andrew M. Watkins, and Paramjit S. Arora Source Type: research

[ASAP] Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C ‑Type Lectin Langerin
ACS Chemical BiologyDOI: 10.1021/acschembio.2c00626 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - September 26, 2022 Category: Chemistry Authors: Hengxi Zhang, Carlos Modenutti, Yelha Phani Kumar Nekkanti, Maxime Denis, Iris A. Bermejo, Jonathan Lefe ̀bre, Kateryna Che, Dongyoon Kim, Marten Kagelmacher, Dennis Kurzbach, Marc Nazaré, and Christoph Rademacher Source Type: research

[ASAP] Method for Identifying Sequence Motifs in Pre-miRNAs for Small-Molecule Binding
ACS Chemical BiologyDOI: 10.1021/acschembio.2c00452 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - September 23, 2022 Category: Chemistry Authors: Yusuke Takashima, Asako Murata, Kei Iida, Ayako Sugai, Masatoshi Hagiwara, and Kazuhiko Nakatani Source Type: research

[ASAP] Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5
ACS Chemical BiologyDOI: 10.1021/acschembio.2c00234 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - September 23, 2022 Category: Chemistry Authors: Stefanie Kampen & , David Rodri ́guez & , Morten Jrgensen, Monika Kruszyk-Kujawa, Xinyan Huang, Michael Collins, Jr, Noel Boyle, Damien Maurel, Axel Rudling, Guillaume Lebon, and Jens Carlsson Source Type: research

[ASAP] Development of a New DHFR-Based Destabilizing Domain with Enhanced Basal Turnover and Applicability in Mammalian Systems
ACS Chemical BiologyDOI: 10.1021/acschembio.2c00518 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - September 19, 2022 Category: Chemistry Authors: Emi Nakahara, Vishruth Mullapudi, Gracen E. Collier, Lukasz A. Joachimiak, and John D. Hulleman Source Type: research

[ASAP] < italic toggle="yes" > In Vitro < /italic > Reconstitution of Fimsbactin Biosynthesis from < named-content content-type="genus-species" xlink:type="simple" > Acinetobacter baumannii < /named-content >
ACS Chemical BiologyDOI: 10.1021/acschembio.2c00573 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - September 19, 2022 Category: Chemistry Authors: Jinping Yang and Timothy A. Wencewicz Source Type: research

[ASAP] Stable Isotope-Guided Metabolomics Reveals Polar-Functionalized Fatty-Acylated RiPPs from < italic toggle="yes" > Streptomyces < /italic >
ACS Chemical BiologyDOI: 10.1021/acschembio.2c00601 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - September 16, 2022 Category: Chemistry Authors: Shumpei Asamizu, Shinta Ijichi, Shotaro Hoshino, Hansaem Jo, Hidenori Takahashi, Yuko Itoh, Sohkichi Matsumoto, and Hiroyasu Onaka Source Type: research

[ASAP] < italic toggle="yes" > In Vivo < /italic > Prenylomic Profiling in the Brain of a Transgenic Mouse Model of Alzheimer ’s Disease Reveals Increased Prenylation of a Key Set of Proteins
ACS Chemical BiologyDOI: 10.1021/acschembio.2c00486 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - September 15, 2022 Category: Chemistry Authors: Angela Jeong, Shelby A. Auger, Sanjay Maity, Kristina Fredriksen, Rui Zhong, Ling Li, and Mark D. Distefano Source Type: research

[ASAP] Covalent Catalytic Strategies for Enzymes That Modify RNA Molecules on their Tripartite Building Blocks
ACS Chemical BiologyDOI: 10.1021/acschembio.2c00584 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - September 14, 2022 Category: Chemistry Authors: Christopher T. Walsh Source Type: research

[ASAP] Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33 α and TRIM33β Bromodomains
ACS Chemical BiologyDOI: 10.1021/acschembio.2c00266 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - September 13, 2022 Category: Chemistry Authors: Angelina R. Sekirnik1, Jessica K. Reynolds1, Larissa See1, Joseph P. Bluck12, Amy R. Scorah1, Cynthia Tallant3, Bernadette Lee1, Katarzyna B. Leszczynska4, Rachel L. Grimley, R. Ian Storer, Marta Malattia6, Sara Crespillo6, Sofia Caria6, Stephanie Duclos6 Source Type: research

[ASAP] Combinatorial Anticancer Drug Screen Identifies Off-Target Effects of Epigenetic Chemical Probes
ACS Chemical BiologyDOI: 10.1021/acschembio.2c00451 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - September 9, 2022 Category: Chemistry Authors: Samir H. Barghout, Mandeep K. Mann, Ahmed Aman, Yifan Yu, Matthew G. Alteen, Aaron D. Schimmer, Matthieu Schapira, Cheryl H. Arrowsmith, and Dalia Barsyte-Lovejoy Source Type: research

[ASAP] Comparative Metabolomics Reveals a Bifunctional Antibacterial Conjugate from Combined-Culture of < named-content content-type="genus-species" xlink:type="simple" > Streptomyces hygroscopicus < /named-content > HOK021 and < named-content content-type="genus-species" xlink:type="simple" > Tsukamurella pulmonis < /named-content > TP-B0596
ACS Chemical BiologyDOI: 10.1021/acschembio.2c00585 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - September 8, 2022 Category: Chemistry Authors: Shumpei Asamizu, Abrory Agus Cahya Pramana, Sung-Jin Kawai, Yoshichika Arakawa, and Hiroyasu Onaka Source Type: research

[ASAP] Exploring the Surface of the Ectodomain of the PD-L1 Immune Checkpoint with Small-Molecule Fragments
ACS Chemical BiologyDOI: 10.1021/acschembio.2c00583 (Source: ACS Chemical Biology)
Source: ACS Chemical Biology - September 8, 2022 Category: Chemistry Authors: Radoslaw Kitel, Ismael Rodri ́guez, Xabier del Corte, Jack Atmaj, Magdalena Żarnik, Ewa Surmiak, Damian Muszak, Katarzyna Magiera-Mularz, Grzegorz M. Popowicz, Tad A. Holak, and Bogdan Musielak Source Type: research