The COMFORT trial: a randomised control trial comparing group-based COMpassion-FOcussed therapy and breathing pattern ReTraining with treatment as usual on the psychological functioning of patients diagnosed with cancer recurrence during COVID
DiscussionTo our knowledge, this protocol describes the first RCT which directly examines the effect of a group-based psychological intervention on Irish patients experiencing cancer recurrence in the context of COVID-19. The outcome of this trial is likely to be twofold: It will determine if the psychological intervention achieves its primary objective of distress amelioration 3 months post-intervention and to establish the feasibility of delivering this intervention in a virtual format.Trial registrationClinicalTrials.gov NCT05518591. Registered on 25 August 2022. All items from the World Health Organization Trial Regi...
Source: Trials - February 6, 2023 Category: Research Source Type: clinical trials
Predicting and Monitoring Outcomes in Autoimmune Encephalitis
Condition: Autoimmune Encephalitis Intervention: Other: Observational study Sponsors: Royal College of Surgeons, Ireland; University of Oxford Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 3, 2023 Category: Research Source Type: clinical trials
Neoadjuvant Trastuzumab Deruxtecan (T-DXd) With Response-directed Definitive Therapy in Early Stage HER2-positive Breast Cancer (SHAMROCK Study)
Condition: HER2-positive Breast Cancer Intervention: Drug: trastuzumab deruxtecan (T-DXd) (IV) Sponsor: Cancer Trials Ireland Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 2, 2023 Category: Research Source Type: clinical trials
