TWiV 949: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses progress toward poliomyelitis eradication in Pakistan, polio by the numbers , influenza and COVID-19 vaccination coverage among health care personnel, phase 1/2a safety and immunogenicity of an adenovirus 26 vector RSV vaccine encoding prefusion F in adults 18–50 years and RSV seropositive children 12–24 months, receipt of first and second doses of JYNNEOS vaccine for prevention of Monkeypox, distinguishing SARS-CoV-2 persistence and reinfection, Novavax NVX-COV2373 triggers potent neutralization of Omicron sub-lineages, association between regular physical activity a...
Source: This Week in Virology - MP3 Edition - October 29, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 947: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the prediction of upcoming global infection burden of influenza seasons after relaxation of public health and social measures during the COVID-19 pandemic, severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters, and how successful immunomodulators for treatment of COVID-19 have opened the pathway for comparative trials. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt at Vaccinated.US Prediction of upcoming global infection burden...
Source: This Week in Virology - MP3 Edition - October 22, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 946: Poo versus flu
Angela Mingarelli joins TWiV to discuss whether the gut microbiota of bats confers tolerance to influenza virus infection in mice, and primate hemorrhagic fever-causing arteriviruses that can reproduce in human cells and might be capable of infecting humans. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Guest: Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Research assistant position at FDA (pdf) Support MicrobeTV with a Spike t-shirt (Vaccinated.us) Bat gut microbiota and flu infection in ...
Source: This Week in Virology - MP3 Edition - October 16, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 938: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin reviews the public health response to poliovirus in New York, impact of mandatory influenza vaccination, monkeypox in a young infant, health care worker exposure to monkeypox virus, monkeypox testing delays, transmission potential of monkeypox virus, TPOXX trial for monkeypox, detection of SARS-CoV-2 subgenomic mRNA, mucosal IgA against SARS-CoV-2, BNT262b2 against Omicron, awareness and use of SARS-CoV-2 antivirals, comparable outcomes for Bebtelovimab and Nirmatrelvir, and COVID-19 and Alzheimer's disease. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a...
Source: This Week in Virology - MP3 Edition - September 24, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 934: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses variant influenza virus infections: recommendations for identification, treatment, and prevention for summer and fall 2022, low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals, using the right tools at the right time for SARS-COV-2 infection, onset and window of SARS-COV-2 infectiousness and temporal correlation with symptom onset, transmission of SARS-COV-2: a review of viral, host, and environmental factors, antibody persistence and safety through 6 months after heterologous orally aerosolized Ad5-nCoV in individuals...
Source: This Week in Virology - MP3 Edition - September 10, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 932: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses vaccine effectiveness against influenza illness in children, clinical manifestations of infection with poliovirus, spike protein-independent attenuation of SARS-CoV-2 Omicron variant in laboratory mice, concordance of SARS-CoV-2 results in self-collected nasal swabs vs swabs collected by health care workers in children and adolescents, probable animal-to-human transmission of SARS-CoV-2 causing a pet shop-related outbreak, laboratory-confirmed COVID-19–associated hospitalizations among adults during BA.2 variant, SARS-CoV-2 specific T-cells and antibodies, Nirmatr...
Source: This Week in Virology - MP3 Edition - September 3, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 931: Driven to immunodistraction
TWiV reviews the genetic characterization of a new strain of type 2 oral polio vaccine and its implications for eradication, and how a polymorphism in humans comprising a single amino acid change in an antibody molecule regulates vaccine elicitation of broadly neutralizing antibodies against influenza virus HA. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Characterization of novel OPV2 from humans (MMWR) Engineering nOPV2 (TWiV 756) Genome sequence of Rockland...
Source: This Week in Virology - MP3 Edition - August 28, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 892: COVID-19 clinical update #111 with Dr. Daniel Griffin
In COVID-19 clinical update #111, Dr. Griffin discusses vaccine coverage and mortality in Hong Kong, immune response to boosters in kids, hospitalization of kids, breath based diagnostic test, viral co-infections, bivalent mRNA vaccine, intramuscular Evusheld, and global long COVID. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Vaccine coverage and mortality, Hong Kong (MMWR) Kids behind on routine vaccinations (Politico) Immune response to booster, 5-11 year olds (Pfizer) Children and vaccination (AAP) Hospitalization of 5-11 year olds (MMWR) Test usin...
Source: This Week in Virology - MP3 Edition - April 23, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 887: Bonfire of the monocytes
TWiV explains why this season’s influenza vaccine is not protecting against mild to moderate disease caused by H3N2 virus, and that antibody-dependent entry of SARS-CoV-2 into monocytes is a major contributor to severe COVID-19. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Amy Rosenfeld Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Seasonal influenza vaccine effectiveness (MMWR) Properties of a dominant H3N2 variant (bioRxiv) Scott Henley on influenza vaccine growth in eggs (TWiV 480) Fc receptor dependent entry of SARS-CoV-2 into ...
Source: This Week in Virology - MP3 Edition - April 10, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 878: Shape matters sometimes
TWiV revisits chronic wasting disease of cervids and the ability of the prions to infect meadow voles and raccoons, and the suggestion that stochastic assembly of influenza virus particles may play a role in phenotypic diversity. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Amy Rosenfeld Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode CWD in meadow voles and raccoons (Emerg Inf Dis) Unusual infectious agents (Virology Live) Low fidelity influenza virus assembly (Cell) Shape-shifting viruses (TWiV 743) From variolous effluvia to VLPs (T...
Source: This Week in Virology - MP3 Edition - March 20, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 832: Heavy metal flu fighters
TWiV reviews the vials labeled smallpox that were not, re-emergence of enterovirus D68 in Europe, efficacy of inactivated SARS-CoV-2 vaccine, and cellular correlates of protection for an oral influenza virus vaccine. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Amy Rosenfeld Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Smallpox vials contain vaccinia virus (6abc.com) European re-emergence of enterovirus D68 (Eurosurveill) Efficacy of inactivated SARS-CoV-2 vaccine (Lancet) Cellular correlates of protection for oral flu vaccine (Cell Host M...
Source: This Week in Virology - MP3 Edition - November 21, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 824: Immunogoblins in the nose and lungs
TWiV explores the properties of the spike glycoproteins of an influenza B virus discovered in the Wuhan spiny eel, and protection against SARS-CoV-2 infection one year after mRNA-1273 vaccination of nonhuman primates. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode HA and NA of Wuhan spiny eel influenza virus (Nat Comm) Protection one year after mRNA-1273 vaccination (bioRxiv) Letters read on TWiV 824 Timestamps by Jolene. Thanks! Weekly Picks Dickson – Best of Gilda Radner Brianne ...
Source: This Week in Virology - MP3 Edition - October 31, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 769: MIS-C and leaky gut
On this episode of TWiV, Novavax COVID-19 vaccine demonstrates 90% overall efficacy, preventing an antigenically disruptive change during growth of influenza virus vaccine in chicken eggs, and MIS-C is driven by loss of the gut mucosal barrier. Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker Click arrow to play Download TWiV 769 (68 MB .mp3, 114 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ASV Vaccine Town Hall 2:05 Novavax vaccine efficacy reported (Novavax) H3N2 glycosylation in eggs (TWiV 480) Preventing antigenically disruptive HA chan...
Source: This Week in Virology - MP3 Edition - June 17, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
