Combination of SBRT and Immunotherapy in Small Hepatocellular Carcinoma (HSBRT2402)
Conditions: Hepatocellular Carcinoma Interventions: Radiation: Stereotactic body radiotherapy; Drug: Sintilimab Sponsors: Sun Yat-sen University; Fifth Affiliated Hospital, Sun Yat-Sen University; Ningbo Medical Center Lihuili Eastern Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials
Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA
Conditions: Cancer; Solid Tumor; Colorectal Cancer; Breast Cancer; Ovarian Cancer; Lung Cancer; Targeted Therapy; Chemotherapy; Immunotherapy; Precision Therapy Interventions: Genetic: SNP; Drug: Palbociclib 125mg; Drug: Bevacizumab Sponsors: Lebanese University; Haykel Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 12, 2024 Category: Research Source Type: clinical trials
CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults
Conditions: Diffuse Midline Glioma, H3 K27M-Mutant; Recurrent High Grade Glioma Interventions: Drug: Treatment with CD200AR-L Sponsors: OX2 Therapeutics Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 12, 2024 Category: Research Source Type: clinical trials
Neoadjuvant Chemoradiotherapy Followed by Sequential Immunotherapy for Thoracic Esophageal Squamous Cell Carcinoma
Conditions: Esophageal Squamous Cell Carcinoma Interventions: Drug: paclitaxel; Drug: carboplatin; Drug: tislelizumab; Radiation: radiotherapy Sponsors: Qiu Guoqin Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials
Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases
Conditions: Colorectal Cancer Metastatic; Liver Metastases; Colorectal Cancer Interventions: Drug: Botensilimab; Drug: Balstilimab; Drug: AGEN1423; Radiation: Radiation Sponsors: Weill Medical College of Cornell University; Agenus Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials
Neoadjuvant Almonertinib Followed by Chemo-immunotherapy in II-IIIB EGFR-mutant NSCLC
Conditions: Non Small Cell Lung Cancer; EGFR Gene Mutation Interventions: Drug: almonertinib; Drug: Carboplatin; Drug: Nab paclitaxel Sponsors: Guangdong Provincial People ' s Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials
Phase I Clinical Study of Tumor-associated Lymph Node T Cell Therapy for Advanced Solid Tumors
Conditions: Advanced Solid Tumor; Tumor Associated Lymph Node T Cell; Immunotherapy Interventions: Drug: Tumor Associated Lymph node T cell; Drug: cyclophosphamide; Drug: IL-2; Drug: Serplulimab Injection Sponsors: Guangzhou FineImmune Biotechnology Co., LTD. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials
Exercise and Diet Interventions During Immunotherapy in Melanoma Patients
Conditions: Melanoma (Skin); Skin Cancer; Advanced Melanoma Interventions: Behavioral: Exercise Program; Behavioral: Diet Program Sponsors: Dana-Farber Cancer Institute; World Cancer Research Fund International Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
Postoperative Adjuvant Immunotherapy for Hepatocellular Carcinoma: Risk Factor Analysis and Prognostic Modelling
Conditions: Hepatocellular Carcinoma; Adjuvant Immunotherapy; Checkpoint Inhibitor Interventions: Drug: Anti-PD-1 monoclonal antibody Sponsors: Chen Xiaoping Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
Analysing HIgh Dose Probiotic Peanut Oral Immunotherapy (PPOIT) and High Dose Peanut Oral Immunotherapy (OIT) Versus LOw Dose Peanut OIT for Peanut Allergy
Conditions: Peanut Allergy Interventions: Drug: Peanut Oral Powder [PEANUT POWDER]; Dietary Supplement: Probiotic (LGG ®, Lactobacillus Rhamnosus) or placebo probiotic (maltodextrin) Sponsors: Murdoch Childrens Research Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 6, 2024 Category: Research Source Type: clinical trials
Relation Between Tumor-draining Lymph Nodes Metastasis Pattern and Non-small Cell Lung Cancer Neoadjuvant Immunotherapy Effectiveness
Conditions: Lung Cancer Interventions: Drug: Immunotherapy Sponsors: Sun Yat-sen University; Jiangmen Central Hospital; Henan Cancer Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2024 Category: Research Source Type: clinical trials
The Predictive Biomarkers in Patients With Locally Advanced Non-small Cell Lung Cancer
Conditions: Locally Advanced Non-small Cell Lung Cancer Interventions: Radiation: concurrent or sequential chemoradiotherapy; Drug: Immunotherapy Sponsors: Cancer Institute and Hospital, Chinese Academy of Medical Sciences Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 1, 2024 Category: Research Source Type: clinical trials
A Phase II Study Bolstering Outcomes by Optimizing Immunotherapy Strategies With Evolocumab and Nivolumab in Patients With Metastatic Renal Cell Carcinoma (BOOST-RCC)
Conditions: Metastatic Renal Cell Carcinoma Interventions: Drug: Evolocumab; Drug: Nivolumab Sponsors: M.D. Anderson Cancer Center; Bristol-Myers Squibb; Cancer Prevention Research Institute of Texas; United States Department of Defense Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 29, 2024 Category: Research Source Type: clinical trials
Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell Carcinoma
Conditions: Esophageal Squamous Cell Carcinoma; Efficacy; Toxicity Interventions: Drug: Induction Immunotherapy-Toripalimab; Drug: Induction Chemotherapy-Albumin-paclitaxel combined with cisplatin; Radiation: Radiotherapy; Drug: Apatinib; Drug: Capecitabine Sponsors: Sun Yat-sen University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials
Impact of Splenectomy on the Efficacy of Targeted Therapy and Immunotherapy in Unresectable HCC Patients With Cirrhotic Hypersplenism
Conditions: Unresectable Hepatocellular Carcinoma Interventions: Combination Product: Splenectomy+Targeted therapy+ Immunotherapy Sponsors: Zhiyong Huang; Wuhan Union Hospital, China; Wuhan University; Renmin Hospital of Wuhan University; Taihe Hospital; Hubei Cancer Hospital; Xiangyang Central Hospital of Hubei Province; Wuhan Central Hospital; The Third People ' s Hospital of Yichang City Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials
