CCR Grand Rounds: Learning the Molecular Logic of Cancer
CCR Grand Rounds “ Learning the Molecular Logic of Cancer ” Eliezer Van Allen, M.D.Associate Professor, Medicine, Harvard Medical SchoolChief, Division of Population Sciences, Dana-Farber Cancer InstituteFriday, April 26, 202412:00 – 1:00 p.m.Lipsett AmphitheaterDr. Eliezer (Eli) Van Allen is an Associate Professor of Medicine at Harvard Medical School, Chief of the Division of Population Sciences at the Dana-Farber Cancer Institute, an Institute Member at the Broad Institute of MIT and Harvard, and a Member Researcher in The Parker Institute for Cancer Immunotherapy at the Dana-Farber Cancer Institute. As both ...
Source: Videocast - All Events - April 16, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video
CCR Grand Rounds: Glypicans as Cancer Targets for CAR-T Immunotherapy
CCR Grand Rounds “ Glypicans as Cancer Targets for CAR-T Immunotherapy ” Mitchell Ho, Ph.D.Senior Investigator& Deputy ChiefLaboratory of Molecular BiologyCenter for Cancer Research, NCIFriday, April 19, 202412:00 – 1:00 p.m.Lipsett AmphitheaterAlso available to view via NIH Videocast.Dr. Mitchell Ho is a Senior Investigator and Deputy Chief of the Laboratory of Molecular Biology and Director of the Antibody Engineering Program at the Center for Cancer Research, NCI. Dr. Ho's research encompasses investigating molecular mechanisms by which glypicans such as GPC1, GPC2 and GPC3 regulate Wnt signaling, as well as d...
Source: Videocast - All Events - April 15, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video
IOTN Capstone Meeting
One of the original Blue Ribbon Panel Recommendations was for NCI to create a translational science network devoted exclusively to immunotherapy. To achieve these goals, the Immuno-Oncology Translational Network (IOTN) was established to foster collaborative team science approaches to accelerate the discovery of new immune targets and evaluate novel immune-based therapies and combination approaches that eliminate established cancers in adults or to prevent cancers before they occur.This IOTN Capstone Meeting will highlight scientific accomplishments and inter-Network collaborations across the IOTN. The IOTN will be ending ...
Source: Videocast - All Events - April 1, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video
IOTN Capstone Meeting
One of the original Blue Ribbon Panel Recommendations was for NCI to create a translational science network devoted exclusively to immunotherapy. To achieve these goals, the Immuno-Oncology Translational Network (IOTN) was established to foster collaborative team science approaches to accelerate the discovery of new immune targets and evaluate novel immune-based therapies and combination approaches that eliminate established cancers in adults or to prevent cancers before they occur.This IOTN Capstone Meeting will highlight scientific accomplishments and inter-Network collaborations across the IOTN. The IOTN will be ending ...
Source: Videocast - All Events - March 28, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH ProtIG seminar: Immunopeptidomics Frontier: Practical Deployments Today, Revolutionary Visions Tomorrow
The science that investigates the ensembles of all peptides associated with human leukocyte antigen (HLA) molecules is termed " immunopeptidomics " and is typically driven by mass spectrometry (MS) technologies. Recent advances in MS technologies, neoantigen discovery, and cancer immunotherapy have catalyzed the launch of the Human Immunopeptidome Project with the goal of providing a complete map of the human immunopeptidome and making the technology so robust that it will be available in every clinic. In this presentation, I will describe our latest progress in the field for the discovery of tumor-specific antigens and vi...
Source: Videocast - All Events - March 20, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video
CCR Grand Rounds: Biomaterials to Promote T Cell Immunity
CCR Grand Rounds “ Biomaterials to Promote T Cell Immunity ” David J. Mooney, Ph.D.Founding Core Faculty& Lead, Immuno-MaterialsWyss Institute at Harvard UniversityRobert P. Pinkas Family Professor of BioengineeringHarvard John A. Paulson School of Engineering and Applied SciencesFriday, March 22, 202412:00 – 1:00 p.m.Lipsett AmphitheaterDr. David J. Mooney is the Pinkas Family Professor of Bioengineering in the Harvard School of Engineering and Applied Sciences and a Core Faculty Member of the Wyss Institute. His laboratory designs biomaterials to promote regeneration and immunotherapy. He is a member o...
Source: Videocast - All Events - February 28, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video
Biomaterials to Promote T Cell Immunity
CCR Grand Rounds “ Biomaterials to Promote T Cell Immunity ” David J. Mooney, Ph.D.Founding Core Faculty& Lead, Immuno-MaterialsWyss Institute at Harvard UniversityRobert P. Pinkas Family Professor of BioengineeringHarvard John A. Paulson School of Engineering and Applied SciencesFriday, March 22, 202412:00 – 1:00 p.m.Lipsett AmphitheaterAlso available to view via NIH Videocast.Dr. David Mooney is the Pinkas Family Professor of Bioengineering in the Harvard School of Engineering and Applied Sciences and a Core Faculty Member of the Wyss Institute. His laboratory designs biomaterials to promote regeneration and im...
Source: Videocast - All Events - February 21, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video
Microbiome, metabolites and mucosal immunity
Dr. Kathy McCoy is a Professor in the Department of Physiology and Pharmacology, Cumming School of Medicine, member of the Snyder Institute, Scientific Director of the International Microbiome Center, and holds the Killam Memorial Chair at the University of Calgary, Canada. Her research group uses germ-free and gnotobiotic models to investigate the cellular and molecular mechanisms by which the microbiome regulates host immunity and physiology. She is particularly interested in the dynamic interplay between the gut microbiota and the innate and adaptive immune systems. Her research aims to understand how exposure to intest...
Source: Videocast - All Events - February 16, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video
Designing Nanoparticles to Probe and Cross Biological Barriers to Immunotherapy
The Mucosal Associated Immune System Engineering and Lymphatics (MAISEL) Lab ’ s research integrates nanotechnology, materials science, and tissue engineering with physiology, medicine, and immunology to probe lymphatics and extracellular barriers via novel ex vivo and in vitro models and nanoparticles. We are particularly focused on studying mucosal barriers to the therapeutic path from the mucosal lumen to the downstream lymph nodes and integrating the newly created knowledge to design immune modulatory therapeutic interventions. We have made significant progress in understanding how nanoparticle material properties li...
Source: Videocast - All Events - November 14, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Immune evasion of stem cells in health and cancer
The Agudo lab is focused on the study of immune evasion of stem cells in both autoimmunity and cancer. Our goal is to identify targets to protect tissues for regeneration as well as mechanisms to ensure effective responses to immunotherapy in cancer patients. Dr. Agudo has recently discovered a population of quiescent cancer stem cells in breast cancer that survive during T cell attack and lead to resistance to immunotherapy.Air date: 11/29/2023 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - November 14, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
CCR Grand Rounds: Biomaterials to Promote T Cell Immunity
CCR Grand Rounds “ Biomaterials to Promote T Cell Immunity ” David J. Mooney, Ph.D. Founding Core Faculty& Lead, Immuno-Materials Wyss Institute at Harvard University Robert P. Pinkas Family Professor of Bioengineering Harvard John A. Paulson School of Engineering and Applied Sciences Friday, November 3, 202312:00 – 1:00 p.m.Lipsett Amphitheater Dr. David Mooney is the Pinkas Family Professor of Bioengineering in the Harvard School of Engineering and Applied Sciences and a Core Faculty Member of the Wyss Institute. His laboratory designs biomaterials to promote regeneration and immunotherapy. He is a member of th...
Source: Videocast - All Events - October 30, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
CCR Grand Rounds: Big Data Approaches to Study Intercellular Signaling During Tumor Immune Evasion
CCR Grand Rounds “ Big Data Approaches to Study Intercellular Signaling During Tumor Immune Evasion ”
Peng Jiang, Ph.D.
Stadtman Investigator
Cancer Data Science Laboratory
Center for Cancer Research, NCI
Friday, September 29, 2023
12:00 – 1:00 p.m.
Lipsett Amphitheater
Dr. Peng Jiang started his research program at the National Cancer Institute (NCI) in July 2019. His lab focuses on developing big data and artificial intelligence frameworks to identify biomarkers and new therapeutic approaches for cancer immunotherapies in solid tumors. Before joining NCI, he fi nished his postdoctoral training at the Dana Far...
Source: Videocast - All Events - September 19, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
CCR Grand Rounds: Immunotherapy of Liver Cancer: From Bench to Bedside and Back to the Bench
CCR Grand Rounds“ Immunotherapy of Liver Cancer: From Bench to Bedside and Back to the Bench ”
Tim F. Greten, M.D.
Deputy Chief, Thoracic and GI Malignancies Branch
Co-Director, NCI CCR Liver Cancer Program
Center for Cancer Research, NCI
Dr. Greten is a physician-scientist who uses his medical expertise in gastroenterology, hepatology and medical oncology along with his research expertise in tumor immunology to develop novel treatments for patients with cancer. He heads a research team to study the tumor microenvironment in the li ver in the context of hepatocellular carcinoma, cholangiocarcinoma and liver metasta...
Source: Videocast - All Events - September 13, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
SOX9 is a key component of RUNX2-regulated transcriptional circuitry in osteosarcoma
Osteosarcoma (OS) is the most common bone cancer in children and adolescents. Although the 5-year survival rate of most OS is more than 70%, it drops to 25% for those with recurrent or metastasized tumors. Furthermore, the standard care of OS has not changed in the past three or more decades, and there is no FDA-approved targeted therapy and immunotherapy for OS. Therefore, there is a great need to develop new therapeutic targets to reduce side effects and improve the prognosis for OS patients. The lack of targetable genetic alterations in OS suggests that transcriptional and epigenetic events are involved in the etiology ...
Source: Videocast - All Events - September 5, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Anti-Beta-Amyloid Passive Immunotherapy for Alzheimer ’ s Dementia and Amyloid Related Imaging Abnormalities (ARIA): What ’ s Next? (Day 2)
This workshop brings together leading experts and researchers from around the world to discuss the latest advancements and challenges in the field of anti-beta amyloid passive immunotherapy. Goals of this workshop are to identify scientific gaps and opportunities, discuss potential animal models, learn how to identify patients at risk for serious adverse events, understand the role for comorbidities and their treatments, and identify potential biomarkers or targets to protect patients at risk.Air date: 9/29/2023 8:30:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - August 29, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
