Cancer's power harnessed — lymphoma mutations supercharge T cells
In this episode:0:46 Borrowing tricks from cancer could help improve immunotherapyT cell based immunotherapies have revolutionised the treatment of certain types of cancer. However these therapies — which involved taking someone’s own T cells and reprogramming them to kill cancer cells — have struggled to treat solid tumours, which put up multiple defences. To overcome these, a team has taken mutations found in cancer cells that help them thrive and put them into therapeutic T cells. Their results show these powered-up cells are more efficient at targeting solid tumours, but don’t turn cancerous themselves.Research...
Source: Nature Podcast - February 7, 2024 Category: Science Authors: Springer Nature Limited Source Type: podcasts

JAMA Oncology : Immunotherapy Initiation at the End of Life in Patients With Metastatic Cancer in the US
Interview with Sajid A. Khan, MD, author of Immunotherapy Initiation at the End of Life in Patients With Metastatic Cancer in the US. Hosted by Mary L. (Nora) Disis, MD. Related Content: Immunotherapy Initiation at the End of Life in Patients With Metastatic Cancer in the US (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - January 4, 2024 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

How mummies were prepared: Ancient Egyptian pots spill secrets
In this episode:00:47 Chemical analysis of ancient embalming materialsMummification was a significant part of ancient Egyptian culture but, despite decades of research, much is unknown about the substances and methods used during the process. Now a team have analysed the contents of ceramic vessels uncovered in an embalming workshop that dates back to around 600 BC. The results reveal that some substances assumed to be a single thing were actually mixtures, while some came from far outside Egypt, providing a clearer picture of ancient mummification practices.Research article: Rageot et al.News and Views: Recipes for ancien...
Source: Nature Podcast - February 1, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

JAMA Oncology : Adoption of Innovative Therapies Across Oncology Practices
Interview with Nancy L. Keating, MD, MPH, author of Adoption of Innovative Therapies Across Oncology Practices—Evidence From Immunotherapy. Hosted by Jack West, MD. Related Content: Adoption of Innovative Therapies Across Oncology Practices—Evidence From Immunotherapy (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - January 5, 2023 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

JAMA Otolaryngology –Head & Neck Surgery : Use of FDG-PET/CT to Predict Immunotherapy Treatment Response in Patients With OCSCC
Interview with Heather Jacene MD, and Jonathan D. Schoenfeld, MD, MPH, authors of Use of Fluoro-[F]-Deoxy-2-D-Glucose Positron Emission Tomography/Computed Tomography to Predict Immunotherapy Treatment Response in Patients With Squamous Cell Oral Cavity Cancers Hosted by Joseph P. Bradley, MD. (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - January 20, 2022 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

JAMA Oncology : Early Readout on Overall Survival of Patients With Melanoma Treated With Immunotherapy
Interview with Laurent Dercle, MD, PhD, author of Early Readout on Overall Survival of Patients With Melanoma Treated With Immunotherapy Using a Novel Imaging Analysis.  Hosted by Jack West, MD. (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - January 20, 2022 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

JAMA Oncology : Anti –PD-1 Immunotherapy in Microsatellite-Stable Tumors With 10 or More Mutations per Megabase
Interview with Luc GT Morris, MD MSc, author of Response Rates to Anti–PD-1 Immunotherapy in Microsatellite-Stable Solid Tumors With 10 or More Mutations per Megabase (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - February 18, 2021 Category: General Medicine Authors: The JAMA Network Source Type: podcasts

Asthma Guidelines Update 2020 - Diagnosis and Management
The National Asthma Education and Prevention Program (NAEPP) of the NIH has updated its guideline recommendations for diagnosis and treatment of asthma patients. Michelle M. Cloutier, MD, from UConn Health, Stephanie Lovinsky-Desir, MD, of Columbia University Irving Medical Center, and JAMA Associate Editor George O'Connor, MD, MS, from Boston Medical Center join JAMA's Q&A series to discuss what's new, including revised advice about • Use of intermittent inhaled corticosteroids (ICSs) • Use of add-on long-acting muscarinic antagonists (LAMAs) • Use of fractional exhaled nitric oxide (FeNO) measurement as a diagnosti...
Source: JAMA Author Interviews - December 10, 2020 Category: General Medicine Authors: JAMA Network Source Type: podcasts

Fighting cancer with CRISPR, and dating ancient rock art with wasp nests
On this week’s show, Staff Writer Jennifer Couzin-Frankel joins host Sarah Crespi to talk about a Science paper that combines two hot areas of research-link—CRISPR gene editing and immunotherapy for cancer—and tests it in patients.   Sarah also talks with Damien Finch, a Ph.D. candidate in the School of Earth Sciences at the University of Melbourne, about the Kimberly region of Australia and dating its ice age cave paintings using charcoal from nearby wasp nests. Episode page  This week’s episode was edited by Podigy.   Listen to previous podcasts.   About the Science Pod...
Source: Science Magazine Podcast - February 6, 2020 Category: Science Authors: Science Magazine Source Type: podcasts

Fighting cancer with CRISPR, and dating ancient rock art with wasp nests
On this week’s show, Staff Writer Jennifer Couzin-Frankel joins host Sarah Crespi to talk about a Science paper that combines two hot areas of research-link—CRISPR gene editing and immunotherapy for cancer—and tests it in patients.   Sarah also talks with Damien Finch, a Ph.D. candidate in the School of Earth Sciences at the University of Melbourne, about the Kimberly region of Australia and dating its ice age cave paintings using charcoal from nearby wasp nests. Episode page  This week’s episode was edited by Podigy.   Listen to previous podcasts.   About the Science Podcast   Download a transcript ...
Source: Science Magazine Podcast - February 6, 2020 Category: Science Authors: Science Magazine Source Type: podcasts

Fighting cancer with CRISPR, and dating ancient rock art with wasp nests
On this week ’s show, Staff Writer Jennifer Couzin-Frankel joins host Sarah Crespi to talk about a Science paper that combines two hot areas of research—CRISPR gene editing and immunotherapy for cancer—and tests it in patients. Sarah also talks with Damien Finch, a Ph.D. candidate in the School of Earth Sc iences at the University of Melbourne, about the Kimberly region of Australia and dating its ice age cave paintings using charcoal from nearby wasp nests. This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: Joseph Br adshaw; Music: ...
Source: Science Magazine Podcast - February 6, 2020 Category: Science Authors: Science Tags: Scientific Community Source Type: podcasts

Fighting cancer with CRISPR, and dating ancient rock art with wasp nests
On this week ’s show, Staff Writer Jennifer Couzin-Frankel joins host Sarah Crespi to talk about a Science paper that combines two hot areas of research—CRISPR gene editing and immunotherapy for cancer—and tests it in patients. Sarah also talks with Damien Finch, a Ph.D. candidate in the School of Earth S ciences at the University of Melbourne, about the Kimberly region of Australia and dating its ice age cave paintings using charcoal from nearby wasp nests. This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). (Source: Science Magazine Podcast)
Source: Science Magazine Podcast - February 5, 2020 Category: Science Authors: Science Tags: Scientific Community Source Type: podcasts

TWiV 565: Karolinska virology
From the Karolinska Institute in Stockholm, Vincent speaks with Niklas Björkström, Ali Mirazimi, and Matti Sällberg about their work on the impact of chronic hepatitis C virus infection on NK cells, Crimean-Congo hemorrhagic fever virus vaccines, and immunotherapy to block entry of hepatitis B and D viruses. Hosts: Vincent Racaniello Guests: Niklas Björkström, Ali Mirazimi, and Matti Sällberg Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Karolinska Huddinge CCHV experimental vaccines (J Virol) Increased NK function after antiviral cessation (J Inf Dis) I...
Source: This Week in Virology - MP3 Edition - September 15, 2019 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Alternate Dosing For Immunotherapy
John Freuhauf, M.D., PhD, discusse Lowering Toxicity through alternate dosing. Author: Annual-Meeting Added: 08/21/2019 (Source: Oncology Tube)
Source: Oncology Tube - August 22, 2019 Category: Cancer & Oncology Source Type: podcasts

Taofeek Owonikoko, MD Discusses lurbinectedin as a Potential Practice Changing in SCLC Treatment
Lurbinectedin, a potential practice changing drug if approved, will be the only agent available in SCLC tested with immunotherapy. PharmaMar to submit New Drug Application (NDA) for lurbinectedin unde... Author: PharmaMar Added: 08/21/2019 (Source: Oncology Tube)
Source: Oncology Tube - August 21, 2019 Category: Cancer & Oncology Source Type: podcasts