Association of Interleukin-2 Gene Polymorphism with Henoch-sch önlein Purpura Nephritis
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):319-326. doi: 10.18502/ijaai.v22i3.13060.ABSTRACTHenoch-Schönlein purpura nephritis (HSPN) is a common vasculitis that mostly affects children, and previous studies have indicated that genetic factors may influence disease susceptibility. The aim of this study was to evaluate a possible association of three interleukin-2 (IL-2) gene polymorphisms (rs3136534, rs2069776, and rs2069762) with HSPN in the Chinese population. A total of 81 patients with HSPN and 200 healthy children were enrolled. The distribution of genotypes, allelic frequencies, and haplotype frequencies among...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Jiajia Cao Junfeng Zhang Hui Xu Wei Li Jianrong Shi Qing Ye Source Type: research
Association of Interleukin-2 Gene Polymorphism with Henoch-sch önlein Purpura Nephritis
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):319-326. doi: 10.18502/ijaai.v22i3.13060.ABSTRACTHenoch-Schönlein purpura nephritis (HSPN) is a common vasculitis that mostly affects children, and previous studies have indicated that genetic factors may influence disease susceptibility. The aim of this study was to evaluate a possible association of three interleukin-2 (IL-2) gene polymorphisms (rs3136534, rs2069776, and rs2069762) with HSPN in the Chinese population. A total of 81 patients with HSPN and 200 healthy children were enrolled. The distribution of genotypes, allelic frequencies, and haplotype frequencies among...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Jiajia Cao Junfeng Zhang Hui Xu Wei Li Jianrong Shi Qing Ye Source Type: research
Association of Interleukin-2 Gene Polymorphism with Henoch-sch önlein Purpura Nephritis
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):319-326. doi: 10.18502/ijaai.v22i3.13060.ABSTRACTHenoch-Schönlein purpura nephritis (HSPN) is a common vasculitis that mostly affects children, and previous studies have indicated that genetic factors may influence disease susceptibility. The aim of this study was to evaluate a possible association of three interleukin-2 (IL-2) gene polymorphisms (rs3136534, rs2069776, and rs2069762) with HSPN in the Chinese population. A total of 81 patients with HSPN and 200 healthy children were enrolled. The distribution of genotypes, allelic frequencies, and haplotype frequencies among...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Jiajia Cao Junfeng Zhang Hui Xu Wei Li Jianrong Shi Qing Ye Source Type: research
Association of Interleukin-2 Gene Polymorphism with Henoch-sch önlein Purpura Nephritis
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):319-326. doi: 10.18502/ijaai.v22i3.13060.ABSTRACTHenoch-Schönlein purpura nephritis (HSPN) is a common vasculitis that mostly affects children, and previous studies have indicated that genetic factors may influence disease susceptibility. The aim of this study was to evaluate a possible association of three interleukin-2 (IL-2) gene polymorphisms (rs3136534, rs2069776, and rs2069762) with HSPN in the Chinese population. A total of 81 patients with HSPN and 200 healthy children were enrolled. The distribution of genotypes, allelic frequencies, and haplotype frequencies among...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Jiajia Cao Junfeng Zhang Hui Xu Wei Li Jianrong Shi Qing Ye Source Type: research
Association of Interleukin-2 Gene Polymorphism with Henoch-sch önlein Purpura Nephritis
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):319-326. doi: 10.18502/ijaai.v22i3.13060.ABSTRACTHenoch-Schönlein purpura nephritis (HSPN) is a common vasculitis that mostly affects children, and previous studies have indicated that genetic factors may influence disease susceptibility. The aim of this study was to evaluate a possible association of three interleukin-2 (IL-2) gene polymorphisms (rs3136534, rs2069776, and rs2069762) with HSPN in the Chinese population. A total of 81 patients with HSPN and 200 healthy children were enrolled. The distribution of genotypes, allelic frequencies, and haplotype frequencies among...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Jiajia Cao Junfeng Zhang Hui Xu Wei Li Jianrong Shi Qing Ye Source Type: research
Association of Interleukin-2 Gene Polymorphism with Henoch-sch önlein Purpura Nephritis
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):319-326. doi: 10.18502/ijaai.v22i3.13060.ABSTRACTHenoch-Schönlein purpura nephritis (HSPN) is a common vasculitis that mostly affects children, and previous studies have indicated that genetic factors may influence disease susceptibility. The aim of this study was to evaluate a possible association of three interleukin-2 (IL-2) gene polymorphisms (rs3136534, rs2069776, and rs2069762) with HSPN in the Chinese population. A total of 81 patients with HSPN and 200 healthy children were enrolled. The distribution of genotypes, allelic frequencies, and haplotype frequencies among...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Jiajia Cao Junfeng Zhang Hui Xu Wei Li Jianrong Shi Qing Ye Source Type: research
Association of Interleukin-2 Gene Polymorphism with Henoch-sch önlein Purpura Nephritis
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):319-326. doi: 10.18502/ijaai.v22i3.13060.ABSTRACTHenoch-Schönlein purpura nephritis (HSPN) is a common vasculitis that mostly affects children, and previous studies have indicated that genetic factors may influence disease susceptibility. The aim of this study was to evaluate a possible association of three interleukin-2 (IL-2) gene polymorphisms (rs3136534, rs2069776, and rs2069762) with HSPN in the Chinese population. A total of 81 patients with HSPN and 200 healthy children were enrolled. The distribution of genotypes, allelic frequencies, and haplotype frequencies among...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Jiajia Cao Junfeng Zhang Hui Xu Wei Li Jianrong Shi Qing Ye Source Type: research
Association of Interleukin-2 Gene Polymorphism with Henoch-sch önlein Purpura Nephritis
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):319-326. doi: 10.18502/ijaai.v22i3.13060.ABSTRACTHenoch-Schönlein purpura nephritis (HSPN) is a common vasculitis that mostly affects children, and previous studies have indicated that genetic factors may influence disease susceptibility. The aim of this study was to evaluate a possible association of three interleukin-2 (IL-2) gene polymorphisms (rs3136534, rs2069776, and rs2069762) with HSPN in the Chinese population. A total of 81 patients with HSPN and 200 healthy children were enrolled. The distribution of genotypes, allelic frequencies, and haplotype frequencies among...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Jiajia Cao Junfeng Zhang Hui Xu Wei Li Jianrong Shi Qing Ye Source Type: research
Association of Interleukin-2 Gene Polymorphism with Henoch-sch önlein Purpura Nephritis
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):319-326. doi: 10.18502/ijaai.v22i3.13060.ABSTRACTHenoch-Schönlein purpura nephritis (HSPN) is a common vasculitis that mostly affects children, and previous studies have indicated that genetic factors may influence disease susceptibility. The aim of this study was to evaluate a possible association of three interleukin-2 (IL-2) gene polymorphisms (rs3136534, rs2069776, and rs2069762) with HSPN in the Chinese population. A total of 81 patients with HSPN and 200 healthy children were enrolled. The distribution of genotypes, allelic frequencies, and haplotype frequencies among...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Jiajia Cao Junfeng Zhang Hui Xu Wei Li Jianrong Shi Qing Ye Source Type: research
Association of Interleukin-2 Gene Polymorphism with Henoch-sch önlein Purpura Nephritis
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):319-326. doi: 10.18502/ijaai.v22i3.13060.ABSTRACTHenoch-Schönlein purpura nephritis (HSPN) is a common vasculitis that mostly affects children, and previous studies have indicated that genetic factors may influence disease susceptibility. The aim of this study was to evaluate a possible association of three interleukin-2 (IL-2) gene polymorphisms (rs3136534, rs2069776, and rs2069762) with HSPN in the Chinese population. A total of 81 patients with HSPN and 200 healthy children were enrolled. The distribution of genotypes, allelic frequencies, and haplotype frequencies among...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Jiajia Cao Junfeng Zhang Hui Xu Wei Li Jianrong Shi Qing Ye Source Type: research
Association of Interleukin-2 Gene Polymorphism with Henoch-sch önlein Purpura Nephritis
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):319-326. doi: 10.18502/ijaai.v22i3.13060.ABSTRACTHenoch-Schönlein purpura nephritis (HSPN) is a common vasculitis that mostly affects children, and previous studies have indicated that genetic factors may influence disease susceptibility. The aim of this study was to evaluate a possible association of three interleukin-2 (IL-2) gene polymorphisms (rs3136534, rs2069776, and rs2069762) with HSPN in the Chinese population. A total of 81 patients with HSPN and 200 healthy children were enrolled. The distribution of genotypes, allelic frequencies, and haplotype frequencies among...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Jiajia Cao Junfeng Zhang Hui Xu Wei Li Jianrong Shi Qing Ye Source Type: research
Association of Interleukin-2 Gene Polymorphism with Henoch-sch önlein Purpura Nephritis
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):319-326. doi: 10.18502/ijaai.v22i3.13060.ABSTRACTHenoch-Schönlein purpura nephritis (HSPN) is a common vasculitis that mostly affects children, and previous studies have indicated that genetic factors may influence disease susceptibility. The aim of this study was to evaluate a possible association of three interleukin-2 (IL-2) gene polymorphisms (rs3136534, rs2069776, and rs2069762) with HSPN in the Chinese population. A total of 81 patients with HSPN and 200 healthy children were enrolled. The distribution of genotypes, allelic frequencies, and haplotype frequencies among...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Jiajia Cao Junfeng Zhang Hui Xu Wei Li Jianrong Shi Qing Ye Source Type: research
Association of Interleukin-2 Gene Polymorphism with Henoch-sch önlein Purpura Nephritis
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):319-326. doi: 10.18502/ijaai.v22i3.13060.ABSTRACTHenoch-Schönlein purpura nephritis (HSPN) is a common vasculitis that mostly affects children, and previous studies have indicated that genetic factors may influence disease susceptibility. The aim of this study was to evaluate a possible association of three interleukin-2 (IL-2) gene polymorphisms (rs3136534, rs2069776, and rs2069762) with HSPN in the Chinese population. A total of 81 patients with HSPN and 200 healthy children were enrolled. The distribution of genotypes, allelic frequencies, and haplotype frequencies among...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Jiajia Cao Junfeng Zhang Hui Xu Wei Li Jianrong Shi Qing Ye Source Type: research
Henoch –schonlein purpura following exposure to SARS-CoV2 vaccine or infection: a systematic review and a case report
ConclusionsOur results suggest that the immune response elicited by SARS-CoV2 vaccine or infection could play a role in the development of HSP. Current research suggests a possible role of IgA in immune hyperactivation, highlighted by early seroconversion to IgA found in some COVID-19 patients who develop IgA vasculitis. (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - July 27, 2023 Category: Emergency Medicine Source Type: research
