How Does Pediatric Sj ö gren Syndrome Present?
Discussion Sjögren Syndrome (SS) is named for Swedish ophthalmologist Henrik Sjögren who published a case series in 1933 describing patients with dry eyes and arthritis. SS is a “chronic autoimmune inflammatory exocrinopathy” that is characterized by lymphocytic infiltration of the lacrimal and salivary glands and has various degrees of systematic involvement. Keratoconjunctivitis sicca and xerostomia are the main clinical symptoms. Sicca is a Latin word meaning dry. Dryness of the eyes and mouth without evidence of autoimmune disease is called Sicca syndrome or Sicca complex. SS can be primary or se...
Source: PediatricEducation.org - December 11, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Medical News Today: Henoch-Sch önlein purpura: Causes, symptoms, and treatment
What is Henoch-Sch önlein purpura, who does it affect, and what are the causes? Learn about the diagnosis of Henoch-Schönlein purpura and how it is treated. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 15, 2017 Category: Consumer Health News Tags: Dermatology Source Type: news
Henoch-Schönlein purpura following high-voltage electric burn injury: A case report and review of the literature - Duan X, Yu D, Yu C, Wang B, Guo Y.
Henoch-Schönlein Purpura (HSP) is a systemic vasculitis of unknown cause, with immune-mediated inflammation of the small vessels, which is characterized by a series of clinical symptoms, such as purpuric rash, colicky abdominal pain, arthritis and acute g... (Source: SafetyLit)
Source: SafetyLit - February 26, 2016 Category: Global & Universal Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news
Intussusception By The Numbers
Discussion Intussusception occurs when one segment of the gastrointestinal tract telescopes into an adjacent segment. The outer receiving segment of bowel is known as the intussuscipiens and the inner inverting segment is known as the intussusceptum. It occurs most often in children between 2 months to 5 years, with a peak incidence between 4-10 months. Males are more often affected than females by 3:2. It also occurs more often after abdominal operations particularly in the first 2 weeks. It is the second most common acute abdominal emergency in children after appendicitis. In adults ~80% have an underlying cause or lead ...
Source: PediatricEducation.org - September 7, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
What Are Common Drug Eruptions in Children?
Patient Presentation A 4-year-old female came to clinic because of a rash for 24 hours. The pruritic rash began the evening before with a few red spots on her trunk. She had slept well, but this morning they were spreading and enlarging in size on her trunk, neck and extremities and did not seem to come and go. She also had a fever and her mother thought that she wasn’t moving as well and seemed to be sore. The patient had been started on cefaclor 9 days earlier for an ear infection and upper respiratory tract infection symptoms. She had previously taken penicillins and cephalosporin antibiotics without any problems...
Source: PediatricEducation.org - July 27, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Gene Linked With Pediatric Vasculitis
(MedPage Today) -- HLA-DRB1 locus may harbor culprit behind Henoch-Schonlein purpura. (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - December 5, 2014 Category: Pediatrics Source Type: news
What Causes Testicular Pain?
Discussion Most inguinal hernias are indirect (i.e. the hernia passes through the internal inguinal ring and down the inguinal canal); only 2% of all hernias in children are direct hernias (i.e. the hernia directly protrudes through the floor of the inguinal canal). Indirect inguinal hernias occur in about 1-5% of infants. They occur on the right side (60%), left side (30%) and bilaterally (10%) and they are more common in premature infants of both sexes. The male : female ratio of inguinal hernias is 4-8 : 1. The chief complaint of testicular or scrotal pain always raises concerns. The acute scrotum generally has pain, ...
Source: PediatricEducation.org - September 1, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
What Causes Proteinuria?
Discussion Proteinuria occurs relatively often in pediatric practice with 5-15% of school children having transient proteinuria, the most common cause. However, proteinuria can be a sign of kidney disease. Therefore, it is important to evaluate the proteinuria in light of the clinical situation. A good history and physical examination along with a full urinalysis and/or BUN and creatinine, or urine protein/creatinine ratio may be all that is necessary. Another patient with edema, hypertension or hematuria needs a fuller evaluation and treatment. Proteinuria is usually categorized into three groups to assist with evaluation...
Source: PediatricEducation.org - August 18, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
What Causes Leg Pain?
Discussion “Growing pains” of the legs are a common complaint in children. Heterogeneous studies from 1928-2004 have found prevalence rates of 2.6-49.4% in children ages 4-19. The studies are heterogeneous because of time, location, and especially definition of growing pains. A study of 1445, 4-6 year olds in 2004 using a validated tool showed a prevalence rate of 36.9%. The definition of growing pains used by Peterson in the 2004 study is chronic “…intermittent (nonarticular) pains in both legs that generally occur late in the day or at night…” with a normal physical examination and ...
Source: PediatricEducation.org - May 19, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
What is in the Differential Diagnosis of Purpura?
Discussion Children presenting with rashes are common but certain characteristics may be concerning such as descriptions of petechiae or purpura. Purpura are characterized by non-blanching skin lesions between 3-10 mm in size that are caused by bleeding into the skin. Usually they are reddish-purplish hence the name purpura coming from the Latin word. Non-blanching lesions that are 10 mm are ecchymosis. Henoch-Schönlein purpura (HSP) is a generalized vasculitis that commonly involves the gastrointestinal tract, kidneys, skin and joints, and is especially seen in children 2-11 years old. Classically HSP presents with p...
Source: PediatricEducation.org - May 5, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
What is Acute Hemorrhagic Edema of Infancy?
Discussion The differential diagnosis for acute hemorrhagic edema of infancy (AHEI) is similar to purpura and includes: Vascultitis Henoch-Schonlein purpura (HSP) Drug induced Kawasaki disease Rocky Mountain Spotted Fever Trauma induced Infectious Disease Meningococcemia Sepsis Dermatologic Erythema multiforme Gianotti Crosti Hemorrhagic urticaria Sweet’s syndrome Child maltreatment Neonatal lupus Learning Point Acute hemorrhagic edema of infancy (AHEI, also called Seidlmayer or postinfectious cockade purpura, medallion-like purpura, or Finkelstein’s disease) is an uncommon, self-limited cutaneous leukocy...
Source: PediatricEducation.org - January 28, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news