Remote Monitoring for Peritoneal Dialysis: Interview with Aly ElBadry, CEO of CloudCath
CloudCath, a medtech company based in San Francisco, has created the CloudCath system, a remote monitoring technology that provides clinicians with data on the spent dialysate fluid of at-home peritoneal dialysis patients. CloudCath is incorporated into the drain line of peritoneal dialysis systems, and wirelessly transmits data to the cloud, with proprietary algorithms then highlighting issues, such as infection, to clinicians. At present, abnormalities with peritoneal dialysis patients may not be flagged in a timely manner. For instance, patients are advised to check their dialysate using the “newspaper test,...
Source: Medgadget - July 14, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Medicine cloudcath peritonealdialysis Source Type: blogs

This ECG Pattern Told the Story When the Patient Could Not
 Submitted by Spencer Lord MD, written by Alex Bracey with edits by Meyers and SmithA patient presents as a transfer from an outside facility. On arrival, he appeared air hungry, volume overloaded, and agitated. EMS was not available for a history at the time and the patient was unable to provide any details regarding his circumstances. During the initial minutes of his resuscitation the following ECG was performed:This ECG is pathognomonic. What is it?Sinus bradycardia with first degree AV blockWide, bizarre QRS complexes with STE in V1 and aVRPeaked T waves in I, II, V4-V6QRS duration is nearly 200 ms.There is a lar...
Source: Dr. Smith's ECG Blog - July 2, 2021 Category: Cardiology Authors: Bracey Source Type: blogs

Fight Aging! Newsletter, January 25th 2021
In conclusion, our studies highlight the important role of the tyrosine degradation pathway and position TAT as a link between neuromediator production, dysfunctional mitochondria, and aging. (Source: Fight Aging!)
Source: Fight Aging! - January 24, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

SENS Research Foundation on Recent Plasma Dilution Research
The SENS Research Foundation scientific staff here discuss the recent results demonstrating benefits to an aged metabolism resulting from dilution of blood plasma. Plasma dilution is a comparatively simple process, straightforward enough that self-experimenters with the support of physicians recently replicated the animal study protocol in a few human volunteers. Dilution of blood plasma also dilutes harmful signal molecules present in an aged body, such as those generated by an increased burden of lingering senescent cells. This reduces chronic inflammation and improves tissue function in older individuals. When ...
Source: Fight Aging! - January 19, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

First Dedicated Pediatric and Neonatal Acute Dialysis Machine Released U.S.
Medtronic is releasing in the United States the industry’s first and only dedicated pediatric and neonatal acute dialysis machine. The Carpediem (Cardio-Renal Pediatric Dialysis Emergency Machine) has been in development for about a decade and the first in-human use was announced back in 2014. Having now received FDA marketing authorization, Medtronic is now making it available to hospitals around the country. Cincinnati Children’s Hospital Medical Center already has these installed and in use. The continuous renal replacement therapy (CRRT) device is indicated for patients between 2.5 and 10 kilograms (5...
Source: Medgadget - December 10, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Cardiac Surgery Critical Care Medicine Pediatrics Urology medtronic Source Type: blogs

Delayed GI Symptoms and a Liver Transplant
​A 16-year-old boy presented to an emergency department in rural Pennsylvania for nausea, vomiting, and diarrhea. He reported diffuse abdominal cramping that had started two hours earlier. Shortly prior to arrival, he had multiple episodes of nonbloody diarrhea and emesis. He had no significant past medical history, and was not currently taking any medications or supplements. Initially, the history he gave was limited due to a language barrier. His sister was also being evaluated for similar symptoms.The boy's vital signs were a heart rate of 130 bpm, a blood pressure of 100/50 mm Hg, a respiratory rate of 26 bpm, an oxy...
Source: The Tox Cave - November 30, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

“ Dialysable LV dysfunction In CKD ” : Myocardial edema clearance plays a role.
In CKD, LVH is a near-constant feature with echo showing thick, bright echoes from IVS. The LV mass increases, partly due to physiological hypertrophy ,also contributed by deposits of uremic middle molecules and fluid collection in the interstitium as myocardial edema.This, is recognised as T 2 weighted MRI signals. Chronic fluid stasis may progress to myocardial fibrosis. (Kidney Blood Press Res 2018;43:134–142 )   Effect of Frusemide on myocardial edema  We know, loop diuretics cause aggressive depletion of ECF volume and to a lesser extent Interstitial fluid. The effect of diuretic on myocardial wate...
Source: Dr.S.Venkatesan MD - October 11, 2020 Category: Cardiology Authors: dr s venkatesan Tags: cardiology research topics for fellows cardiology thesis topics Uncategorized myocardial edema in ckd myocardial edema mri Source Type: blogs

Redefining Values in American Health Care
By RICHARD HOEHN, MD Experts claim we could have been better prepared when the COVID-19 pandemic struck in early 2020. With an annual budget of $400-700 million, the Strategic National Stockpile (SNS) is designed to respond to chemical, biological, and other disasters. Its $8 billion inventory included 13,000 ventilators and a limited supply of personal protective equipment, N95 masks, and medical supplies. This left state and local governments scrambling as the COVID-19 pandemic accelerated and the capacity of many hospitals was overwhelmed. Faced with immediate and visible death and suffering, leaders took drastic...
Source: The Health Care Blog - August 6, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Economics Health Policy Healthcare spending Richard Hoen Source Type: blogs

Syncope and Chest Pressure, then an Unusual Bradycardia with Shock
This case is from one of our fantastic 3rd year residents, Aaron Robinson.A woman in her 60s with SyncopeA woman in her 60s presented to a facility with syncope. She had a history of CHF, pulmonary hypertension,CAD s/pCABG, and ESRD on hemodialysis. She had a dialysis run the day prior. Prehospital VS were: BP 115/70, HR 65, RR 12. The patient did not have a 12 lead completed pre-hospital.She arrived at the ED awake, alert, and complaining only ofmild chest discomfort. A 12 lead ECG was immediately completed:Aaron showed this to me and this is what I said:Suggestive of inferior posterior MI, but not dia...
Source: Dr. Smith's ECG Blog - May 15, 2020 Category: Cardiology Authors: Steve Smith Source Type: blogs

Tablo Hemodialysis System Receives FDA Clearance for Home Use
Outset Medical announced that it received FDA 510(k) clearance for its Tablo Hemodialysis System to be used in the home, expanding its existing labeled indication for use in acute and chronic care facilities. Touted by Outset as a “dialysis clinic on wheels,” Tablo is designed to reduce dialysis cost and complexity. The device needs only an electrical outlet and tap water to operate, as it includes water purification and dialysate production on demand. A touchscreen tablet guides the user through setup and treatment, and it can also upload data to the cloud for clinician access. Tablo features automated self-cleanin...
Source: Medgadget - April 6, 2020 Category: Medical Devices Authors: Cici Zhou Tags: Medicine Source Type: blogs

Fist Assist Helps Prep Vein for Dialysis Surgery, Lead to Healthy Fistula
Fist Assist Devices, a small Silicon Valley firm, won the European CE Mark for its eponymous wearable device. The Fist Assist works to widen the vein diameter in preparation for fistula placement and to help with fistula vein dilation in patients requiring hemodialysis. It is worn on the arm twice a day starting at about three months prior to fistula creation surgery. Each session lasts about an hour, during which intermittent compression is applied which tends to slowly increase the cephalic vein size. This is the vein that is typically linked to an artery to create a fistula. After surgery, the Fist Assist is ...
Source: Medgadget - February 26, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Medicine Surgery Vascular Surgery Source Type: blogs

Surfacer FDA Cleared for Unusual Dialysis Central Venous Access
The right internal jugular vein is typically the ideal access point for performing hemodialysis via a central venous catheter. Yet, in close to half of patients there’s an obstruction that makes this either a serious challenge or an impossibility. Now, a device called the Surfacer Inside-Out Access Catheter System has been cleared via the FDA De Novo classification, and can penetrate the obstruction and actually use it to its advantage to restore access to the vein. The device is delivered through the right femoral vein and up into the right internal jugular so it rests within the obstruction. From there, the Sur...
Source: Medgadget - February 19, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Medicine Surgery Vascular Surgery Source Type: blogs

Interview with Medtronic ’s Mark Pacyna on Approval of IN.PACT AV DCB for Failing AV Fistulae
End-stage renal disease (ESRD) patients experiencing kidney failure typically require hemodialysis in order to artificially remove fluid and waste from blood and maintain appropriate electrolyte concentrations. For many patients on hemodialysis, an arteriovenous (AV) fistula is created to link an artery to a vein. Veins are too fragile for frequent access, but arteries are too deep. Creating an AV fistula makes the vein that is linked to an artery more resilient and capable of providing regular vascular access for dialysis. While effective, and a standard of care for ESRD patients, vessel restenosis can occur over time ...
Source: Medgadget - December 5, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Exclusive Medicine Vascular Surgery Source Type: blogs

Sonavex Secures NIH Grant to Pursue New Vascular Surgery Applications
Last week, Sonavex, a Baltimore-based medical device company, announced receipt of a $3M Phase IIB Small Business Innovation Research (SBIR) grant for prospective clinical studies and ongoing research and development of its EchoMark and EchoSure devices. This grant funding from the National Institutes of Health (NIH) will specifically allow Sonavex to validate its technology’s application to arteriovenous (AV) fistula maturation and viability for patients with end-stage renal disease (ESRD). Earlier this year, Sonavex received FDA clearance for its EchoSure 3D ultrasound system. EchoSure, in combination with ...
Source: Medgadget - September 3, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Cardiology Surgery Vascular Surgery Source Type: blogs

New Device Supports Dialysis Fistulas
Vascular Graft Solutions, a company based in Tel Aviv, Israel, has won the European CE Mark for its FRAME FR device for repair and support of high flow and aneurysmal arteriovenous fistulas. These are created in hemodialysis patients to allow for more blood to flow through a vein and give easy access for dialysis needles. Although a properly performed fistula can work for many years, in many patients they tend to dilate and create all kinds of problems, including increased toxicity for the heart. These so-called high flow fistulas are difficult to maintain. The FRAME FR device keeps blood flow within a reasonable...
Source: Medgadget - August 7, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Medicine Source Type: blogs