Sonavex Secures NIH Grant to Pursue New Vascular Surgery Applications

Last week, Sonavex, a Baltimore-based medical device company, announced receipt of a $3M Phase IIB Small Business Innovation Research (SBIR) grant for prospective clinical studies and ongoing research and development of its EchoMark and EchoSure devi...
Source: Medgadget - Category: Medical Devices Authors: Tags: Cardiology Surgery Vascular Surgery Source Type: blogs

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AbstractCOVID-19 is a viral disease due to the infection of the novel Corona virus SARS-CoV-2, that has rapidly spread in many countries until the World Health Organization declared the pandemic from March 11, 2020. Elderly patients and those affected by hypertension, diabetes mellitus, and chronic pulmonary and cardiovascular conditions are more susceptible to present more severe forms of COVID-19. These conditions are often represented in dialytic renal end-stage patients. Moreover, dialysis patients are more vulnerable to infection due to suppression of the immune system. Growing evidences, although still supported by f...
Source: Critical Ultrasound Journal - Category: Radiology Source Type: research
Authors: Mo YW, Sun CY, Song L, Zhou LF, Zhuang TT, Zhong M, Zheng SQ, Chen YG, Chen YH, Liu SX, Liang XL, Fu X Abstract BACKGROUND: The important effect of regular blood flow surveillance on arteriovenous fistula maintenance is emphasized. The ultrasonic dilution technique for blood flow surveillance can be performed during hemodialysis, but there are some limitations. Blood flow is traditionally measured by duplex Doppler ultrasound during the nondialysis period. However, the surveillance workload for arteriovenous fistula has increased with the rapid increase in the hemodialysis population size. Efficient method...
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
ConclusionSerum sclerostin increases with declining renal function in patients with CKD 3 –5ND. Sclerostin is an independent risk factor for carotid atherosclerosis.
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research
This study examines the effect of dry-weight reduction with a standardized lung-ultrasound-guided strategy on ambulatory aortic blood pressure (BP) and arterial stiffness parameters in hemodialysis. METHODS: Seventy-one clinically euvolemic hemodialysis patients with hypertension, were included in this single-blind randomized clinical-trial. Patients were randomized in the active group (n = 35), following dry-weight reduction guided by the total number of US-B lines before a mid-week dialysis session and the control group (n = 36), following standard treatment. Patients underwent office eva...
Source: Journal of Nephrology - Category: Urology & Nephrology Authors: Tags: J Nephrol Source Type: research
A 9-year-old boy with nephropathic cystinosis received intraperitoneal deceased donor renal transplant with steroid-free immunosuppression. Intraoperatively 20 ml of urine was noted; renal scan showed poor perfusion with acceptable renal Doppler ultrasound. Intermittent hemodialysis was reinstated on postoperative day 1 because of fluid overload with anuria. On day 5 abdominal distention, new onset fever (101.1 °F), and hypotension developed. Vancomycin, piperacillin/tazobactam, and fluconazole were initiated.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Nephrology Image Source Type: research
This case is from one of our fantastic 3rd year residents, Aaron Robinson.A woman in her 60s with SyncopeA woman in her 60s presented to a facility with syncope. She had a history of CHF, pulmonary hypertension,CAD s/pCABG, and ESRD on hemodialysis. She had a dialysis run the day prior. Prehospital VS were: BP 115/70, HR 65, RR 12. The patient did not have a 12 lead completed pre-hospital.She arrived at the ED awake, alert, and complaining only ofmild chest discomfort. A 12 lead ECG was immediately completed:Aaron showed this to me and this is what I said:Suggestive of inferior posterior MI, but not dia...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
This study enrolled a total of 16 patients, with 63% being male, 75% with lower-arm arterio-venous fistula and around 43% with previously done angioplasty. 59-Qa measurements were done, and 6 patients underwent angioplasty (one patient for severe upper limb edema, one for access thrombosis, and four for access dysfunction). Qa determination by the urea method had non-significantly lower Qa, (745 mL/min (interquartile range: 509-1143) and 779 mL/min (interquartile range: 530-1160), (p = 0.58)) and high correlation (r = 0.83, p
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
Authors: Cyrek AE, Bernheim J, Juntermanns B, Husen P, Pacha A, Hoffmann JN Abstract BACKGROUND: The autologous arteriovenous fistula is the primary choice to establish hemodialysis access without high failure rates. Intraoperative ultrasound flow measurements of newly created autologous arteriovenous fistulas represent a possibility of quality control and may therefore be a tool to assess their functionality. The aim of our study was to correlate intraoperative blood flow with access patency. METHODS: Between March 2012 and March 2015, intraoperative transit time flow measurements were collected on 89 patients...
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
Abstract BACKGROUND: Muscle wasting, prevalent in hemodialysis (HD) patients diagnosed with protein energy wasting, represents an assessment challenge in the outpatient HD setting. Quadriceps muscle thickness (QMT) and cross-sectional area (CSA) assessment by ultrasound (US) is a potential surrogate measure for muscle wasting. We aimed to determine the validity of US to measure QMT and CSA against the gold standard, computed tomography (CT). METHODS: Twenty-six HD patients underwent US and CT scans on the same day, post-dialysis session. QMT for rectus femoris (RF) and vastus intermedius (VI) muscles was take...
Source: JPEN Journal Of Parenteral And Enteral Nutrition - Category: Nutrition Authors: Tags: JPEN J Parenter Enteral Nutr Source Type: research
Carotid artery flow time corrected for heart rate (CFTc) correlates with intravascular volume changes in adults but has not been studied adequately in the pediatric population. We studied how fluid status changes correlate with CFTc in pediatric patients undergoing hemodialysis. This prospective observational study involved pediatric patients aged 5 –18 y undergoing chronic hemodialysis at a tertiary care children’s hospital in the United States. We measured CFTc by point-of-care ultrasound before and after each hemodialysis session, including passive leg raise.
Source: Ultrasound in Medicine and Biology - Category: Radiology Authors: Tags: Original Contribution Source Type: research
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